Computational integration of nanoscale physical biomarkers and cognitive assessments for Alzheimer’s disease diagnosis and prognosis

Plasma amyloid-β and risk of Alzheimer's disease in the Framingham Heart Study

(2015) Vincent Chouraki et al.   Alzheimers & Dementia

Influence of the β-Sheet Content on the Mechanical Properties of Aggregates during Amyloid Fibrillization

(2015) Francesco Simone Ruggeri et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

New criteria for Alzheimer’s disease: which, when and why?

(2015) Jonathan M. Schott et al.   BRAIN

Quantitative detection of amyloid-β peptides by mass spectrometry: state of the art and clinical applications

(2015) Pauline Bros et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Unbinding forces and energies between a siRNA molecule and a dendrimer measured by force spectroscopy

(2015) Andra C. Dumitru et al.   Nanoscale

Amyloid biomarkers in Alzheimer's disease

(2015) Kaj Blennow et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Autoregulated paracellular clearance of amyloid-  across the blood-brain barrier

(2015) J. Keaney et al.   Science Advances

Cognitive Performance and Cerebrospinal Fluid Biomarkers of Neurodegeneration: A Study of Patients with Bipolar Disorder and Healthy Controls

(2015) Sindre Rolstad et al.   PLoS One

Community Cognitive Screening Using the Self-Administered Gerocognitive Examination (SAGE)

(2014) Douglas W. Scharre et al.   JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES

Cerebrospinal fluid biomarkers in trials for Alzheimer and Parkinson diseases

(2014) Alberto Lleó et al.   Nature Reviews Neurology

Ultrasonic force microscopy for nanomechanical characterization of early and late-stage amyloid-β peptide aggregation

(2014) Claire Tinker-Mill et al.   Scientific Reports

Systems Approach to Neurodegenerative Disease Biomarker Discovery

(2013) Christopher Lausted et al.   Annual Review of Pharmacology and Toxicology

Amyloid-Forming Proteins Alter the Local Mechanical Properties of Lipid Membranes

(2013) Kathleen A. Burke et al.   BIOCHEMISTRY

Quantifying fibronectin adhesion with nanoscale spatial resolution on glycosaminoglycan doped polypyrrole using Atomic Force Microscopy

(2013) Amy Gelmi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Association Study of Clusterin Polymorphism rs11136000 With Late Onset Alzheimer’s Disease in Chinese Han Population

(2012) Jian-Fang Ma et al.   American Journal of Alzheimers Disease and Other Dementias

The Amyloid State of Proteins in Human Diseases

(2012) David Eisenberg et al.   CELL

Nanomechanical properties of single amyloid fibrils

(2012) K K M Sweers et al.   JOURNAL OF PHYSICS-CONDENSED MATTER

Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease

(2012) Randall J. Bateman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cell Stiffness Is a Biomarker of the Metastatic Potential of Ovarian Cancer Cells

(2012) Wenwei Xu et al.   PLoS One

Mechanical Stiffness Grades Metastatic Potential in Patient Tumor Cells and in Cancer Cell Lines

(2011) V. Swaminathan et al.   CANCER RESEARCH

Alzheimer's disease

(2011) Clive Ballard et al.   LANCET

Comparative analysis of nanomechanics of protein filaments under lateral loading

(2011) Max Solar et al.   Nanoscale

Multimodal classification of Alzheimer's disease and mild cognitive impairment

(2011) Daoqiang Zhang et al.   NEUROIMAGE

Alzheimer's Disease: The Challenge of the Second Century

(2011) D. M. Holtzman et al.   Science Translational Medicine

Self-administered Gerocognitive Examination (SAGE)

(2010) Douglas W. Scharre et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Size-dependent neurotoxicity of β-amyloid oligomers

(2010) Paulius Cizas et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Alzheimer's Aβ(1-40) Amyloid Fibrils Feature Size-Dependent Mechanical Properties

(2010) Zhiping Xu et al.   BIOPHYSICAL JOURNAL

A causative link between the structure of aberrant protein oligomers and their toxicity

(2010) Silvia Campioni et al.   Nature Chemical Biology

Biomarkers for Alzheimer's disease: academic, industry and regulatory perspectives

(2010) Harald Hampel et al.   NATURE REVIEWS DRUG DISCOVERY

Cerebrospinal fluid and plasma biomarkers in Alzheimer disease

(2010) Kaj Blennow et al.   Nature Reviews Neurology

Identifying and validating biomarkers for Alzheimer's disease

(2010) Christian Humpel   TRENDS IN BIOTECHNOLOGY

Correlation of mRNA and protein in complex biological samples

(2009) Tobias Maier et al.   FEBS LETTERS

Atomistic simulation of nanomechanical properties of Alzheimer’s Aβ(1–40) amyloid fibrils under compressive and tensile loading

(2009) Raffaella Paparcone et al.   JOURNAL OF BIOMECHANICS

Alzheimer's disease: progress in prediction

(2009) Ronald C Petersen   LANCET NEUROLOGY

Unique Cellular Interaction of Silver Nanoparticles: Size-Dependent Generation of Reactive Oxygen Species

(2008) C. Carlson et al.   JOURNAL OF PHYSICAL CHEMISTRY B