Article
Chemistry, Multidisciplinary
Chenwen Lin, Zijian Du, Nongjian Tao, Di Wang
Summary: The gradient-based colorimetric array sensor (GCAS) overcomes the limitations of traditional colorimetric sensors by inkjet-printing different colorimetric sensing elements on a porous substrate in parallel straight lines. By tracking color gradients and converting them into analyte concentrations in real time, GCAS can detect multiple air pollutants and continuously monitor ambient ozone.
Article
Biophysics
Xueying Zhu, Tian Li, Xin Hai, Sai Bi
Summary: In this study, a nanozyme-based colorimetric sensor array has been proposed as an electronic tongue for the discrimination and quantification of thiols. By integrating modified graphene quantum dots with transition metal ions, different catalytic activities in metal ion-graphene quantum dot ensembles were achieved. Linear discriminant analysis was used to accurately discriminate six thiol analytes. The sensor array was also able to identify thiol-associated diseases using a machine learning algorithm.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Chemistry, Analytical
Jiang Liu, Xiaoxue Liu, Lu Zhang, Liang Zhu, Xuecui Mei, Jun Wei, Yingchun Li
Summary: The TTLS is a novel electrochemical sensor platform with a closed detection chamber and adjustable electrochemical interface area, featuring fast and simple operation, good portability, and high compatibility.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Applied
Guannan Wang, Shaoyun Huang, Hui He, Jiawei Cheng, Tao Zhang, Zhiqiang Fu, Shasha Zhang, Yuzhi Zhou, Houbin Li, Xinghai Liu
Summary: Colorimetric sensing technology was used to monitor food freshness, showing that the sensor accurately reflects ammonia concentration and the freshness of Cod. Using a progress bar indicator can achieve non-destructive, more accurate, and commercially available food quality monitoring.
Article
Chemistry, Analytical
Haiying Shen, Lianhua Dong, Yunhua Gao, Xia Wang, Xinhua Dai
Summary: In this study, a highly integrated microfluidic chip for nucleic acid extraction, amplification, and detection was designed. A hand-held device with precise temperature control and high-quality imaging was developed for experiment and data analysis. The chip allows for mobile point-of-care testing via wireless communication with a smartphone. The results show the potential of this platform for nucleic acid detection.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Yuxiang Pan, Xin Liu, Libin Qian, Yaoxuan Cui, Xubin Zheng, Yuran Kang, Xiang Fu, Shipeng Wang, Ping Wang, Di Wang
Summary: A portable and cost-effective smartphone-integrated analysis platform was developed for fast identification of heavy-metal ions pollution caused by industrial wastewater discharge, utilizing a colorimetric sensor array and pattern recognition algorithms for detection and classification purposes. Achieved accurate identification of common heavy-metal ions and industrial wastewater models, demonstrating the potential for pollution traceability and water quality analysis with the use of smartphones and IoT technology.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Agronomy
Miguel Noguera, Borja Millan, Jose Manuel Andujar
Summary: This study presents a low-cost, handheld multispectral device for assessing crop ripeness. The device, based on a development board, demonstrates good performance in predicting the indicators of soluble solid content and titratable acidity, as validated through experiments with 80 grape samples.
Article
Chemistry, Inorganic & Nuclear
Anthonisamy Roniboss, Ramdas Nishanth Rao, Kaushik Chanda, M. M. Balamurali
Summary: Three model hydrazide derivatives were synthesized and studied for their ability to sense various anions, with benzohydrazide showing the ability to detect both CN- and F- ions. The sensing mechanism may involve deprotonation of the N-H moiety in the hydrazides.
INORGANIC CHEMISTRY COMMUNICATIONS
(2021)
Review
Chemistry, Analytical
Mohammad Amin Rashidi, Rezvan Zendehdel, Shahab Falahi, Soudabeh Ghodsi, Hori Ghaneialvar, Sajad Najafi
Summary: Ammonia has diverse applications but also poses harm to human health and the ecosystem. Colorimetric sensors, particularly those using green synthesized nanoparticles, offer a promising method for ammonia detection and analysis, with advantages such as high accuracy and low power consumption.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Rongbing Li, Jiangtao Ren, Jinxing Chen, Ling Yang, Zhixuan Yu, Yunhui Li, Dengbin Yu, Youxing Fang, Shaojun Dong
Summary: A high-efficiency colorimetric sensor was developed for water toxicity assessment using visual analysis and high-throughput measurement. Photobacterium phoshoreum T3 spp. and Prussian blue were used as the model bacterium and indicator, respectively. The sensor accurately detected acute toxicities of wastewater through optimized experimental conditions. It showed potential in detecting single and joint toxicities of multi-pollutants in water, with IC50 values obtained for various pollutants.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Analytical
Kawin Khachornsakkul, Kuen-Hau Hung, Jung-Jung Chang, Wijitar Dungchai, Chih-Hsin Chen
Summary: A rapid and highly sensitive paper-based colorimetric device for on-site detection of ammonia gas is developed in this study, which operates by detecting the change of color on a paper that has been immobilized with a pH indicator in the presence of NH3 gas. The device can detect NH3 gas concentration within 3 minutes, with a linear relationship between concentration and color signal, showing high selectivity and accuracy.
Article
Chemistry, Analytical
Ying Wang, Jingwen Li, Hongyu Liu, Xu Du, Limin Yang, Jingbin Zeng
Summary: Developed a sensor array with colorimetric and photothermal modes for the identification of multiple pathogenic bacteria. This array based on functionalized nanoparticles can differentiate each bacterium using linear discriminant analysis and show better differentiation compared to other sensing arrays. It can not only distinguish different bacteria but also perform preliminary discrimination of unknown samples.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Yi-Da Zhang, Chen Ma, Yan-Ping Shi
Summary: We have developed a simple and portable device for detecting cholesterol in whole blood, which can be used for early clinical diagnosis and home self-inspection of chronic patients. The device utilizes molecularly imprinted membranes to specifically separate cholesterol from blood and quantifies it based on color change. It is easy to operate, low-cost, and suitable for home self-inspection.
ANALYTICA CHIMICA ACTA
(2022)
Review
Biochemistry & Molecular Biology
Hayati Filik, Asiye Aslihan Avan
Summary: Fast and inexpensive virus identification protocols are crucial in preventing the spread of pandemics, reducing economic and social damages, and expediting clinical recovery. Nanotechnology enables real-time direct identification of pathogenic species, and the use of nanomaterial-based colorimetric sensing approach has gained significant attention due to its simplicity, speed, and cost-effectiveness.
CURRENT MEDICINAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Vedran Budinski, Denis Donlagic
Summary: This paper introduces a miniature all-silica flow-injection sensor with optical fiber-coupled microcell for spectral absorption measurements and microfluidic reagent injection system, allowing for colorimetric chemical sensing in compact spaces and at very low flow rates.
Article
Chemistry, Multidisciplinary
Zheng Li, Zhiwei Wang, Javid Khan, Maria K. LaGasse, Kenneth S. Suslick
Review
Chemistry, Multidisciplinary
Xuan Zhou, Yurun Miao, Kenneth S. Suslick, Dana D. Dlott
ACCOUNTS OF CHEMICAL RESEARCH
(2020)
Review
Chemistry, Multidisciplinary
Zheng Li, Kenneth S. Suslick
Summary: Chemical sensing aims to detect the physical or chemical properties of molecules or ionic species and convert that information into distinguishable output. The olfactory system of animals serves as the prototype for chemical sensing, while the human sense of smell is a fundamental and powerful ability. Olfaction's chemical specificity does not come from specific receptors, but from pattern recognition of combined responses of olfactory receptors.
ACCOUNTS OF CHEMICAL RESEARCH
(2021)
Article
Chemistry, Organic
Hyo Na Kim, Kenneth S. Suslick
Summary: This study quantitatively investigated the fragmentation of organic molecular crystals under ultrasonic irradiation, finding a strong correlation between fragmentation rates and material strength. It was discovered that the rates of sonofragmentation are correlated with the types and densities of imperfections in the crystals. Sonocrystallization processes for pharmaceutical agents were also found to be influenced by sonofragmentation rates, furthering the understanding of mechanochemistry at the interface of the chemical and mechanical worlds.
JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Analytical
Zheng Li, Ruohan Zhang, Xiaohui Lu, Luoyu Hu, Xinyu Wang, Wei Liu, Chen Cui, Xuefeng Liu
Summary: Researchers have developed a colorimetric sensor array based on gold nanoparticles that can accurately identify and quantify various gas-phase oxidants in a cost-effective manner, with high sensitivity and ease of fabrication.
ANALYTICAL CHEMISTRY
(2021)
Article
Nanoscience & Nanotechnology
Linlin Sun, Ruohan Zhang, Luoyu Hu, Xiaofeng Chen, Xiaohui Lu, Zheng Li
Summary: A solid-state colorimetric sensor array was developed to accurately discriminate fragrance bases and detect counterfeit perfumes. The sensor array showed optimized physiochemical robustness and gas response kinetics, enabling fast and accurate detection of perfumes through fingerprinting. Commercial perfume products were successfully distinguished and categorized using chemometric methods, and the sensor array also showed potential for quality assurance of perfumes and cosmetics.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Biophysics
Xiaohui Lu, Chanyu Yao, Linlin Sun, Zheng Li
Summary: MicroRNAs are reliable biomarkers for noninvasive detection of diseases, including cancers. Plasmon-enhanced biosensors are promising tools for miRNA analysis, using enhanced optical output to detect and analyze miRNA.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Chemistry, Multidisciplinary
Sanjun Fan, Xinyu Wang, Yingling Li, Xiofeng Chen, Haotian Chen, Zachary Schultz, Zheng Li
Summary: A high-throughput SERS imaging strategy is demonstrated for screening chemical sensors with sub-nanomolar sensitivities. This method allows for the rapid and cost-effective fabrication of transitional nanostructures and the screening of SERS responsive sites. It has the potential to serve as an alternative tool for ultrasensitive chemical sensing on a wide range of bimetallic substrates.
Review
Chemistry, Analytical
Xiaofeng Chen, Chanyu Yao, Zheng Li
Summary: The development of chemical sensors and biosensors has gained significant attention in the field of food quality inspection. Array-based sensors have the advantage of integrating multiple recognition elements on a single microdetector and can identify diverse molecular targets from complex samples. Microfluidic-based techniques, facilitated by lab-on-a-chip technology, enable rapid and portable monitoring of nutritional or harmful substances with high sensitivity, throughput, and low sample consumption. This article provides a comprehensive review of the latest advancements in array-based chemical sensors and biosensors, with a focus on their applications in detecting foodborne hazardous species or contaminants. Additionally, it highlights the development of miniaturized, sensitive, and selective sensors as the next generation of point-of-care tools.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Xiaofeng Chen, Dongdong Zhang, Qingmei Liu, Sihui Liu, Houlin Li, Zheng Li
Summary: Food allergy is a growing health concern that can impact life quality and even be life-threatening. Exposure to allergenic bioaerosols has a negative effect on respiratory health. Traditional methods for food allergen detection are limited in low-resource settings. This study developed a fluorescent sensor array based on enzyme-linked immunosorbent assay on a herringbone-shaped microfluidic chip for sensitive and multiplexed quantification of foodborne allergens in aerosols. The platform showed excellent field-deployable capacity for allergen determination in aerosols from spiked buffer solutions, making it practical for food safety screening in cooking or food processing sites.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Linlin Sun, Xueliang Liu, Sihui Liu, Xiaofeng Chen, Zheng Li
Summary: The on-chip strategy combining conductive nanosensors with a chaotic gas micromixer enables real-time monitoring of volatile metabolites from urine for accurate diagnosis and classification of urinary tract cancers.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Xiaohui Lu, Kenneth S. Suslick, Zheng Li
Summary: Chemical sensor arrays using optically responsive nanoparticles provide a powerful and versatile method for real-time, sensitive, cost-effective, and portable detection of biochemical analytes, with promising applications in various fields.
ANALYSIS & SENSING
(2023)
Article
Chemistry, Analytical
Xiaohui Lu, Dongdong Zhang, Xiaofeng Chen, Chanyu Yao, Zheng Li
Summary: A versatile microfluidic-SERS barcoding system is developed for sensitive and multiplexed imaging of circulating microRNAs. The system achieves ideal sensitivities at subfemtomolar levels for four miRNAs and has the capability for an integrated liquid biopsy. The on-chip digital profiling of serum miRNAs enables clear discrimination of untreated cancer patients from the healthy cohort and precise classification of tumor stages, metastatic conditions, and subtypes, with an overall accuracy of 94%.
ANALYTICAL CHEMISTRY
(2023)
Article
Materials Science, Multidisciplinary
Zheng Li, Yuxuan Liu, Oindrila Hossain, Rajesh Paul, Shanshan Yao, Shuang Wu, Jean B. Ristaino, Yong Zhu, Qingshan Wei
Summary: An innovative leaf-attachable sensor array has been developed for real-time diagnosis of plant diseases, achieving 97% classification accuracy of 13 individual plant volatiles. The sensor patch allows for rapid profiling of plant volatiles and early diagnosis of diseases like late blight within less than a week post inoculation.
