Stress-Related and Circadian Secretion and Target Tissue Actions of Glucocorticoids: Impact on Health

Separating the Contribution of Glucocorticoids and Wakefulness to the Molecular and Electrophysiological Correlates of Sleep Homeostasis

(2017) Valérie Mongrain et al.   SLEEP

Dynamic transitions in a model of the hypothalamic-pituitary-adrenal axis

(2016) Željko Čupić et al.   CHAOS

The functional and clinical significance of the 24-h rhythm of circulating glucocorticoids

(2016) Henrik Oster et al.   ENDOCRINE REVIEWS

Glucocorticoid receptor beta increases migration of human bladder cancer cells

(2016) Lucien McBeth et al.   Oncotarget

Human Glucocorticoid Receptor β Regulates Gluconeogenesis and Inflammation in Mouse Liver

(2015) Bo He et al.   MOLECULAR AND CELLULAR BIOLOGY

Stress, the Stress System and the Role of Glucocorticoids

(2015) Nicolas C. Nicolaides et al.   NEUROIMMUNOMODULATION

Circadian endocrine rhythms: the hypothalamic-pituitary-adrenal axis and its actions

(2014) Nicolas C. Nicolaides et al.   Annals of the New York Academy of Sciences

Glucocorticoids mediate circadian timing in peripheral osteoclasts resulting in the circadian expression rhythm of osteoclast-related genes

(2014) Yuko Fujihara et al.   BONE

Repeated psychosocial stress at night, but not day, affects the central molecular clock

(2014) Manuela S. Bartlang et al.   CHRONOBIOLOGY INTERNATIONAL

Effects of adrenalectomy on daily gene expression rhythms in the rat suprachiasmatic and paraventricular hypothalamic nuclei and in white adipose tissue

(2014) Yan Su et al.   CHRONOBIOLOGY INTERNATIONAL

Prospective evaluation of long-term safety of dual-release hydrocortisone replacement administered once daily in patients with adrenal insufficiency

(2014) A G Nilsson et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Gene Model 129 (Gm129) Encodes a Novel Transcriptional Repressor That Modulates Circadian Gene Expression

(2014) Yunus Annayev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glucocorticoid Receptor β Stimulates Akt1 Growth Pathway by Attenuation of PTEN

(2014) Lance A. Stechschulte et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adrenal Clocks and the Role of Adrenal Hormones in the Regulation of Circadian Physiology

(2014) Alexei Leliavski et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Rapid intra-adrenal feedback regulation of glucocorticoid synthesis

(2014) J. J. Walker et al.   Journal of the Royal Society Interface

Modulation of glucocorticoid receptor induction properties by core circadian clock proteins

(2014) Dong-Hee Han et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Glucocorticoid Receptor β Acts as a Co-activator of T-Cell Factor 4 and Enhances Glioma Cell Proliferation

(2014) Qian Wang et al.   MOLECULAR NEUROBIOLOGY

Circadian Clock and Stress Interactions in the Molecular Biology of Psychiatric Disorders

(2014) Dominic Landgraf et al.   Current Psychiatry Reports

Chronos: Stress Makes the Clock Tick

(2014) Richard Robinson   PLOS BIOLOGY

Machine Learning Helps Identify CHRONO as a Circadian Clock Component

(2014) Ron C. Anafi et al.   PLOS BIOLOGY

A Novel Protein, CHRONO, Functions as a Core Component of the Mammalian Circadian Clock

(2014) Akihiro Goriki et al.   PLOS BIOLOGY

Overweight and obese children have lower cortisol levels than normal weight children

(2013) E Allansson Kjölhede et al.   ACTA PAEDIATRICA

High-fat diet-induced hyperinsulinemia and tissue-specific insulin resistance in Cry-deficient mice

(2013) Johanna L. Barclay et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Dysregulated diurnal cortisol pattern is associated with glucocorticoid resistance in women with major depressive disorder

(2013) Michael R. Jarcho et al.   BIOLOGICAL PSYCHOLOGY

Dexamethasone induces high-amplitude rhythms in preadipocytes, But hinders circadian expression in differentiated adipocytes

(2013) Maayan Barnea et al.   CHRONOBIOLOGY INTERNATIONAL

Crosstalk between the circadian clock circuitry and the immune system

(2013) Nicolas Cermakian et al.   CHRONOBIOLOGY INTERNATIONAL

The biology of the glucocorticoid receptor: New signaling mechanisms in health and disease

(2013) Robert H. Oakley et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Consensus statement on the diagnosis, treatment and follow-up of patients with primary adrenal insufficiency

(2013) E. S. Husebye et al.   JOURNAL OF INTERNAL MEDICINE

The circadian clock and glucocorticoids – Interactions across many time scales

(2013) Thomas Dickmeis et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Glucocorticoid receptor β regulates injury-mediated astrocyte activation and contributes to glioma pathogenesis via modulation of β-catenin/TCF transcriptional activity

(2013) Ying Yin et al.   NEUROBIOLOGY OF DISEASE

Glucocorticoid-mediated Period2 induction delays the phase of circadian rhythm

(2013) Solmi Cheon et al.   NUCLEIC ACIDS RESEARCH

Circadian patterns of gene expression in the human brain and disruption in major depressive disorder

(2013) J. Z. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diurnal alterations in circadian genes and peptides in major depressive disorder before and after escitalopram treatment

(2013) Su-Xia Li et al.   PSYCHONEUROENDOCRINOLOGY

The five Rs of glucocorticoid action during inflammation: ready, reinforce, repress, resolve, and restore

(2013) John M. Busillo et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Glucocorticoids as Entraining Signals for Peripheral Circadian Oscillators

(2012) Pınar Pezük et al.   ENDOCRINOLOGY

Ultradian corticosterone secretion is maintained in the absence of circadian cues

(2012) Eleanor J. Waite et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Mechanisms of the anti-inflammatory effects of glucocorticoids: genomic and nongenomic interference with MAPK signaling pathways

(2012) Emira Ayroldi et al.   FASEB JOURNAL

AMPK at the crossroads of circadian clocks and metabolism

(2012) Sabine D. Jordan et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Aberrant light directly impairs mood and learning through melanopsin-expressing neurons

(2012) Tara A. LeGates et al.   NATURE

Non-genomic effect of glucocorticoids on cardiovascular system

(2012) Sung Ryul Lee et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Cardiac Atrial Circadian Rhythms in PERIOD2::LUCIFERASE and per1:luc Mice: Amplitude and Phase Responses to Glucocorticoid Signaling and Medium Treatment

(2012) Daan R. van der Veen et al.   PLoS One

Feedback Regulation of Transcriptional Termination by the Mammalian Circadian Clock PERIOD Complex

(2012) K. Padmanabhan et al.   SCIENCE

Shift work at young age is associated with increased risk for multiple sclerosis

(2011) Anna Karin Hedström et al.   ANNALS OF NEUROLOGY

Circadian rhythm of adrenal glucocorticoid: Its regulation and clinical implications

(2011) Sooyoung Chung et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Chronic unpredictable stress induces a reversible change of PER2 rhythm in the suprachiasmatic nucleus

(2011) Wen-Gao Jiang et al.   BRAIN RESEARCH

Predictive modeling of the hypothalamic-pituitary-adrenal (HPA) axis response to acute and chronic stress

(2011) Vladimir M. Markovic et al.   ENDOCRINE JOURNAL

Minireview: Stress-Related Psychiatric Disorders with Low Cortisol Levels: A Metabolic Hypothesis

(2011) Rachel Yehuda et al.   ENDOCRINOLOGY

Flattened Circadian Cortisol Rhythm in Type 2 Diabetes

(2011) F. Lederbogen et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

The adrenal peripheral clock: Glucocorticoid and the circadian timing system

(2011) Gi Hoon Son et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Improved Cortisol Exposure-Time Profile and Outcome in Patients with Adrenal Insufficiency: A Prospective Randomized Trial of a Novel Hydrocortisone Dual-Release Formulation

(2011) G. Johannsson et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Circadian rhythms in the hypothalamo–pituitary–adrenal (HPA) axis

(2011) A. Kalsbeek et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Circadian clock signals in the adrenal cortex

(2011) Takumi Ota et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Cryptochromes mediate rhythmic repression of the glucocorticoid receptor

(2011) Katja A. Lamia et al.   NATURE

Hypothalamic–pituitary–adrenal axis dysfunction in chronic fatigue syndrome

(2011) Andrew S. Papadopoulos et al.   Nature Reviews Endocrinology

Chronic stress affects PERIOD2 expression through glycogen synthase kinase-3β phosphorylation in the central clock

(2011) Chisato Kinoshita et al.   NEUROREPORT

Peripheral CLOCK Regulates Target-Tissue Glucocorticoid Receptor Transcriptional Activity in a Circadian Fashion in Man

(2011) Evangelia Charmandari et al.   PLoS One

Adrenal glucocorticoids have a key role in circadian resynchronization in a mouse model of jet lag

(2010) Silke Kiessling et al.   JOURNAL OF CLINICAL INVESTIGATION

Glucocorticoid Ultradian Rhythmicity Directs Cyclical Gene Pulsing of the Clock Gene Period 1 in Rat Hippocampus

(2010) B. L . Conway-Campbell et al.   JOURNAL OF NEUROENDOCRINOLOGY

Acetylation-mediated epigenetic regulation of glucocorticoid receptor activity: Circadian rhythm-associated alterations of glucocorticoid actions in target tissues

(2010) Tomoshige Kino et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Glucocorticoids and circadian clock control of cell proliferation: At the interface between three dynamic systems

(2010) Thomas Dickmeis et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Considerations of circadian impact for defining 'shift work' in cancer studies: IARC Working Group Report

(2010) R. G. Stevens et al.   OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

Interactions of the circadian CLOCK system and the HPA axis

(2010) Nancy Nader et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Impact of Sleep and Its Disturbances on Hypothalamo-Pituitary-Adrenal Axis Activity

(2010) Marcella Balbo et al.   International Journal of Endocrinology

Glucocorticoid receptor (GR) β has intrinsic, GRα-independent transcriptional activity

(2009) Tomoshige Kino et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Human glucocorticoid receptor isoform β: recent understanding of its potential implications in physiology and pathophysiology

(2009) Tomoshige Kino et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Circadian rhythm transcription factor CLOCK regulates the transcriptional activity of the glucocorticoid receptor by acetylating its hinge region lysine cluster: potential physiological implications

(2009) Nancy Nader et al.   FASEB JOURNAL

Circadian disruption accelerates liver carcinogenesis in mice

(2009) Elisabeth Filipski et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Stress and disorders of the stress system

(2009) George P. Chrousos   Nature Reviews Endocrinology

Glucocorticoid regulation of the circadian clock modulates glucose homeostasis

(2009) A. Y.-L. So et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circadian Control of the NAD+ Salvage Pathway by CLOCK-SIRT1

(2009) Y. Nakahata et al.   SCIENCE

AMPK Regulates the Circadian Clock by Cryptochrome Phosphorylation and Degradation

(2009) K. A. Lamia et al.   SCIENCE

The human glucocorticoid receptor: Molecular basis of biologic function

(2009) Nicolas C. Nicolaides et al.   STEROIDS

The NAD+-Dependent Deacetylase SIRT1 Modulates CLOCK-Mediated Chromatin Remodeling and Circadian Control

(2008) Yasukazu Nakahata et al.   CELL

SIRT1 Regulates Circadian Clock Gene Expression through PER2 Deacetylation

(2008) Gad Asher et al.   CELL

Glucocorticoids and the circadian clock

(2008) Thomas Dickmeis   JOURNAL OF ENDOCRINOLOGY

The genetics of mammalian circadian order and disorder: implications for physiology and disease

(2008) Joseph S. Takahashi et al.   NATURE REVIEWS GENETICS

Adrenal peripheral clock controls the autonomous circadian rhythm of glucocorticoid by causing rhythmic steroid production

(2008) G. H. Son et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA