SGLT1 and SGLT1 Inhibitors: A Role to Be Assessed in the Current Clinical Practice

Discovery of LX2761, a Sodium-Dependent Glucose Cotransporter 1 (SGLT1) Inhibitor Restricted to the Intestinal Lumen, for the Treatment of Diabetes

(2017) Nicole C. Goodwin et al.   JOURNAL OF MEDICINAL CHEMISTRY

Selective sodium-dependent glucose transporter 1 inhibitors block glucose absorption and impair glucose-dependent insulinotropic peptide release

(2015) Robert L. Dobbins et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Localizations of Na+-d-glucose cotransporters SGLT1 and SGLT2 in human kidney and of SGLT1 in human small intestine, liver, lung, and heart

(2014) Ivana Vrhovac et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Efficacy and safety of canagliflozin in subjects with type 2 diabetes and chronic kidney disease

(2013) J.-F. Yale et al.   DIABETES OBESITY & METABOLISM

SGLT inhibitors in management of diabetes

(2013) Abd A Tahrani et al.   Lancet Diabetes & Endocrinology

LX4211, a Dual SGLT1/SGLT2 Inhibitor, Improved Glycemic Control in Patients With Type 2 Diabetes in a Randomized, Placebo-Controlled Trial

(2012) B Zambrowicz et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Why Do SGLT2 Inhibitors Inhibit Only 30-50% of Renal Glucose Reabsorption in Humans?

(2012) J. Liu et al.   DIABETES

Na+-D-glucose Cotransporter SGLT1 is Pivotal for Intestinal Glucose Absorption and Glucose-Dependent Incretin Secretion

(2011) V. Gorboulev et al.   DIABETES

Glucose transport by human renal Na+/d-glucose cotransporters SGLT1 and SGLT2

(2010) Charles S. Hummel et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Enhanced expressions of sodium–glucose cotransporters in the kidneys of diabetic Zucker rats

(2008) Niloofar M. Tabatabai et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Na+-Glucose Transporter-2 Messenger Ribonucleic Acid Expression in Kidney of Diabetic Rats Correlates with Glycemic Levels: Involvement of Hepatocyte Nuclear Factor-1α Expression and Activity

(2007) H. S. Freitas et al.   ENDOCRINOLOGY