Journal
SEMINARS IN INTERVENTIONAL RADIOLOGY
Volume 34, Issue 2, Pages 187-200Publisher
THIEME MEDICAL PUBL INC
DOI: 10.1055/s-0037-1602710
Keywords
high-intensity focused ultrasound; prostate cancer; therapeutic ultrasound; high-intensity directional ultrasound
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Therapeutic ultrasound approaches including high-intensity focused ultrasound (HIFU) are emerging as popular minimally invasive alternative treatments for localized, low-to intermediate risk prostate cancer. FDA approval was recently granted for two ultrasound-guided HIFU devices. Clinical trials for devices using MRI guidance are ongoing. The current level of evidence for whole-gland ultrasound ablation suggests that its clinical efficacy and adverse event rates including erectile dysfunction and urinary incontinence are similar to current definitive therapies such as radical prostatectomy and external-beam radiotherapy. Short-term data suggest that more focal therapy could reduce the rates of adverse events.
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