Umbilical cord blood CD34+ progenitor-derived NK cells efficiently kill ovarian cancer spheroids and intraperitoneal tumors in NOD/SCID/IL2Rgnull mice

Novel strategies to target cancer stem cells by NK cells studies in humanized mice

(2017) Anahid Jewett   Frontiers in Bioscience-Landmark

Natural killer cell-based adoptive immunotherapy eradicates and drives differentiation of chemoresistant bladder cancer stem-like cells

(2016) Margarida Ferreira-Teixeira et al.   BMC Medicine

A novel three-dimensional heterotypic spheroid model for the assessment of the activity of cancer immunotherapy agents

(2016) Sylvia Herter et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Cytotoxicity and infiltration of human NK cells in in vivo-like tumor spheroids

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Cancer statistics, 2015

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Natural Killer Cell Adoptive Transfer Therapy

(2015) Zachary B. Davis et al.   CANCER JOURNAL

The IL-15-Based ALT-803 Complex Enhances Fc RIIIa-Triggered NK Cell Responses and In Vivo Clearance of B Cell Lymphomas

(2015) M. Rosario et al.   CLINICAL CANCER RESEARCH

NK Cells Preferentially Target Tumor Cells with a Cancer Stem Cell Phenotype

(2015) Erik Ames et al.   JOURNAL OF IMMUNOLOGY

NK cells play a significant role in immunosurveillance at the early stage of MLL-AF9 acute myeloid leukemia via CD226/CD155 interactions

(2015) YaJie Wang et al.   Science China-Life Sciences

Induced Pluripotent Stem Cell-Derived Natural Killer Cells for Treatment of Ovarian Cancer

(2015) David L. Hermanson et al.   STEM CELLS

The Aryl Hydrocarbon Receptor Antagonist StemRegenin1 Improves In Vitro Generation of Highly Functional Natural Killer Cells from CD34+Hematopoietic Stem and Progenitor Cells

(2015) Mieke W.H. Roeven et al.   STEM CELLS AND DEVELOPMENT

Cetuximab Reconstitutes Pro-Inflammatory Cytokine Secretions and Tumor-Infiltrating Capabilities of sMICA-Inhibited NK Cells in HNSCC Tumor Spheroids

(2015) Stephan Klöss et al.   Frontiers in Immunology

Utilizing Chimeric Antigen Receptors to Direct Natural Killer Cell Activity

(2015) David L. Hermanson et al.   Frontiers in Immunology

Combined IL-15 and IL-12 drives the generation of CD34+-derived natural killer cells with superior maturation and alloreactivity potential following adoptive transfer

(2015) Jeannette Cany et al.   OncoImmunology

Clearance of acute myeloid leukemia by haploidentical natural killer cells is improved using IL-2 diphtheria toxin fusion protein

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Induced Pluripotent Stem Cells: Challenges and Opportunities for Cancer Immunotherapy

(2014) Patty Sachamitr et al.   Frontiers in Immunology

Intraperitoneal delivery of human natural killer cells for treatment of ovarian cancer in a mouse xenograft model

(2013) Melissa A. Geller et al.   CYTOTHERAPY

Natural Killer Cells Generated from Cord Blood Hematopoietic Progenitor Cells Efficiently Target Bone Marrow-Residing Human Leukemia Cells in NOD/SCID/IL2Rgnull Mice

(2013) Jeannette Cany et al.   PLoS One

Imaging burst kinetics and spatial coordination during serial killing by single natural killer cells

(2013) P. J. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dual Functions of Natural Killer Cells in Selection and Differentiation of Stem Cells; Role in Regulation of Inflammation and Regeneration of Tissues

(2013) Anahid Jewett et al.   Journal of Cancer

Susceptibility of CD24+ ovarian cancer cells to anti-cancer drugs and natural killer cells

(2012) Jiae Koh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

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(2012) Johannes Schindelin et al.   NATURE METHODS

Establishment, Characterization, and Successful Adaptive Therapy against Human Tumors of NKG Cell, a New Human NK Cell Line

(2011) Min Cheng et al.   CELL TRANSPLANTATION

Use of allogeneic NK cells for cancer immunotherapy

(2011) Melissa A Geller et al.   Immunotherapy

Clinical-Grade Generation of Active NK Cells from Cord Blood Hematopoietic Progenitor Cells for Immunotherapy Using a Closed-System Culture Process

(2011) Jan Spanholtz et al.   PLoS One

HLA-E expression by gynecological cancers restrains tumor-infiltrating CD8+ T lymphocytes

(2011) M. Gooden et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ex vivo Expansion of CD56+ NK and NKT-like Lymphocytes from Peripheral Blood Mononuclear Cells of Patients with Ovarian Neoplasia

(2011) P. C. M. Alves et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

A phase II study of allogeneic natural killer cell therapy to treat patients with recurrent ovarian and breast cancer

(2010) Melissa A. Geller et al.   CYTOTHERAPY

Intravital Imaging Reveals Distinct Dynamics for Natural Killer and CD8+ T Cells during Tumor Regression

(2010) Jacques Deguine et al.   IMMUNITY

A Human NK Cell Activation/Inhibition Threshold Allows Small Changes in the Target Cell Surface Phenotype To Dramatically Alter Susceptibility to NK Cells

(2010) T. D. Holmes et al.   JOURNAL OF IMMUNOLOGY

High Log-Scale Expansion of Functional Human Natural Killer Cells from Umbilical Cord Blood CD34-Positive Cells for Adoptive Cancer Immunotherapy

(2010) Jan Spanholtz et al.   PLoS One

Spheroid-based drug screen: considerations and practical approach

(2009) Juergen Friedrich et al.   Nature Protocols