Glioma-induced SIRT1-dependent activation of hMOF histone H4 lysine 16 acetyltransferase in microglia promotes a tumor supporting phenotype

Structural and Functional Role of Acetyltransferase hMOF K274 Autoacetylation

(2016) Cheryl E. McCullough et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glioma-induced inhibition of caspase-3 in microglia promotes a tumor-supportive phenotype

(2016) Xianli Shen et al.   NATURE IMMUNOLOGY

The role of microglia and macrophages in glioma maintenance and progression

(2016) Dolores Hambardzumyan et al.   NATURE NEUROSCIENCE

TET1 modulates H4K16 acetylation by controlling auto-acetylation of hMOF to affect gene regulation and DNA repair function

(2016) Jianing Zhong et al.   NUCLEIC ACIDS RESEARCH

The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas

(2016) D. F. Quail et al.   SCIENCE

Resident microglia rather than peripheral macrophages promote vascularization in brain tumors and are source of alternative pro-angiogenic factors

(2015) Susan Brandenburg et al.   ACTA NEUROPATHOLOGICA

Formaldehyde Crosslinking: A Tool for the Study of Chromatin Complexes

(2015) Elizabeth A. Hoffman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glioma-Associated Microglia/Macrophages Display an Expression Profile Different from M1 and M2 Polarization and Highly Express Gpnmb and Spp1

(2015) Frank Szulzewsky et al.   PLoS One

Resident microglia, and not peripheral macrophages, are the main source of brain tumor mononuclear cells

(2014) Annett Müller et al.   INTERNATIONAL JOURNAL OF CANCER

Histone acetyltransferase hMOF promotes S phase entry and tumorigenesis in lung cancer

(2013) Lei Zhao et al.   CELLULAR SIGNALLING

H4K16 acetylation marks active genes and enhancers of embryonic stem cells, but does not alter chromatin compaction

(2013) G. C. A. Taylor et al.   GENOME RESEARCH

The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy

(2013) Jens Füllgrabe et al.   NATURE

CSF-1R inhibition alters macrophage polarization and blocks glioma progression

(2013) Stephanie M Pyonteck et al.   NATURE MEDICINE

Epigenetics and the Modulation of Neuroinflammation

(2013) Gwenn A. Garden   Neurotherapeutics

Heparan sulfate sulfatase SULF2 regulates PDGFRα signaling and growth in human and mouse malignant glioma

(2012) Joanna J. Phillips et al.   JOURNAL OF CLINICAL INVESTIGATION

SIRT1 Negatively Regulates the Activities, Functions, and Protein Levels of hMOF and TIP60

(2012) L. Peng et al.   MOLECULAR AND CELLULAR BIOLOGY

The neurobiology of sirtuins and their role in neurodegeneration

(2012) Gizem Donmez   TRENDS IN PHARMACOLOGICAL SCIENCES

A dialog between glioma and microglia that promotes tumor invasiveness through the CCL2/CCR2/interleukin-6 axis

(2011) J. Zhang et al.   CARCINOGENESIS

Modulations of hMOF autoacetylation by SIRT1 regulate hMOF recruitment and activities on the chromatin

(2011) Lu Lu et al.   CELL RESEARCH

A dual role of H4K16 acetylation in the establishment of yeast silent chromatin

(2011) Mariano Oppikofer et al.   EMBO JOURNAL

MYST protein acetyltransferase activity requires active site lysine autoacetylation

(2011) Hua Yuan et al.   EMBO JOURNAL

Caspase signalling controls microglia activation and neurotoxicity

(2011) Miguel A. Burguillos et al.   NATURE

Experimental immunotherapy for malignant glioma: lessons from two decades of research in the GL261 model

(2010) Wim Maes et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Opposing effects of hMOF and SIRT1 on H4K16 acetylation and the sensitivity to the topoisomerase II inhibitor etoposide

(2010) N Hajji et al.   ONCOGENE

hMOF, a KAT(8) with Many Lives

(2009) Hestia S. Mellert et al.   MOLECULAR CELL

JNK1 Phosphorylates SIRT1 and Promotes Its Enzymatic Activity

(2009) Nargis Nasrin et al.   PLoS One

Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion

(2009) D. S. Markovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting Interleukin 6 Signaling Suppresses Glioma Stem Cell Survival and Tumor Growth

(2009) Hui Wang et al.   STEM CELLS

Role of hMOF-Dependent Histone H4 Lysine 16 Acetylation in the Maintenance of TMS1/ASC Gene Activity

(2008) P. Kapoor-Vazirani et al.   CANCER RESEARCH

Dynamic Regulation of Nucleosome Positioning in the Human Genome

(2008) Dustin E. Schones et al.   CELL

Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation

(2008) S. Hisahara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The ups and downs of SIRT1

(2008) Hye-Sook Kwon et al.   TRENDS IN BIOCHEMICAL SCIENCES