Article
Immunology
Pei-Ying Wu, Hsin-Yun Sun, Mao-Yuan Chen, Wang-Huei Sheng, Szu-Min Hsieh, Yu-Chung Chuang, Hsi-Yen Chang, Yu-Zhen Luo, Jun-Yu Zhang, Chien-Ching Hung
Summary: Between March and October 2018, a total of 1248 people living with HIV completed questionnaire interviews for cancer screening. Among them, 46.9% (n=585) received free-of-charge cancer screening. The most common reason for refusal to participate in cancer screening was time constraint (50.1%). None of the participants were diagnosed with any of the four cancers.
JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION
(2022)
Article
Multidisciplinary Sciences
Toshio Naito, Hirotake Mori, Kazutoshi Fujibayashi, Shinichi Fukushima, Mayumi Yuda, Nobuyuki Fukui, Shotaro Tsukamoto, Mai Suzuki, Keiko Goto-Hirano, Ryohei Kuwatsuru
Summary: This study reports the status of switch rates and time-to-switch of antiretroviral therapy regimens in Japanese PLWH. The switch rates for NNRTIs and PIs increased continuously over 8 years, while INSTIs had a low switch rate. Most patients initially treated with NNRTIs and PIs switched to INSTIs regardless of switching times.
SCIENTIFIC REPORTS
(2022)
Article
Multidisciplinary Sciences
Juwon Park, Logan S. Dean, Jack Heckl, Louie Mar Gangcuangco, Te-Kie Pedro, Michelle D. Tallquist, Todd B. Seto, Bruce Shiramizu, Dominic C. Chow, Cecilia M. Shikuma
Summary: This study provides evidence that LDGs from PLWH on ART display an immature and altered phenotype with increased NET formation. Plasma NET levels and LDG parameters correlate with blood markers for inflammation and coagulation, suggesting that neutrophil activation and NETs may exert proinflammatory and coagulation effects in PLWH.
SCIENTIFIC REPORTS
(2023)
Article
Substance Abuse
Martin St-Jean, Xinzhe Dong, Hiwot Tafessu, David Moore, William G. Honer, Fidel Vila-Rodriguez, Paul Sereda, Robert S. Hogg, Thomas L. Patterson, Kate Salters, Rolando Barrios, Julio S. G. Montaner, Viviane D. Lima
Summary: The widespread use of triple combination antiretroviral therapy has significantly increased the survival rate of people living with HIV, but in North America, drug overdoses have become a major threat to the life expectancy of HIV-infected individuals. Particularly in British Columbia, drug overdoses have become the leading cause of unintentional death, posing significant challenges to the survival of people living with HIV.
INTERNATIONAL JOURNAL OF DRUG POLICY
(2021)
Review
Medicine, General & Internal
Astri Parawita Ayu, Arie Rahadi, Kevin Kristian, Tara Puspitarini Sani, Aditya Putra, Glenardi Halim, Ghea Mangkuliguna, Theresia Puspoarum Kusumoputri, Yuda Turana
Summary: This planned systematic review aims to investigate potential disparities in the excess burden of neurocognitive impairment (NCI) among people living with HIV (PLWH), and evaluate the impact of psychosocial conditions on NCI.
SYSTEMATIC REVIEWS
(2023)
Article
Multidisciplinary Sciences
Amos Buh, Raywat Deonandan, James Gomes, Alison Krentel, Olanrewaju Oladimeji, Sanni Yaya
Summary: This study aims to assess the prevalence and predictors of antiretroviral therapy (ART) non-adherence among people living with HIV (PLWH) in Cameroon. The results showed that age, education, and alcohol consumption were significantly associated with ART non-adherence. Overall, a high proportion of participants exhibited non-adherence to antiretroviral therapy.
Article
Development Studies
Dylan S. Connor, Aleksander K. Berg, Tom Kemeny, Peter J. Kedron
Summary: The study documents that children growing up in economically left behind places have lower social mobility as adults. Exposure to left behind places is associated with a decline in adult income rank, while exposure to improving conditions leads to better outcomes. These effects are compounded when nearby places also experience economic hardship.
CAMBRIDGE JOURNAL OF REGIONS ECONOMY AND SOCIETY
(2023)
Article
Multidisciplinary Sciences
Amos Buh, Raywat Deonandan, James Gomes, Alison Krentel, Olanrewaju Oladimeji, Sanni Yaya
Summary: This study aimed to assess the factors influencing ART adherence among PLWH in Cameroon. The study identified various barriers to adherence, including patient-related factors, medication-related factors, health service-related factors, stigma, use of alternative treatment, resource limitation, environmental/social factors, and political instability. On the other hand, facilitators of adherence included social support, aligning treatment with daily routines, use of reminders, health sector/caregiver support, and patient's awareness of HIV status/ART knowledge.
Article
Immunology
Kirthana Sharma, Dorothy A. Machalek, Zheng Q. Toh, Demisew Amenu, Mazvita Muchengeti, Andrew K. Ndlovu, Alex Mremi, Bariki Mchome, Andrew J. Vallely, Lynette Denny, Helen Rees, Suzanne M. Garland
Summary: Cervical cancer is a major concern for women globally, particularly in low-income and middle-income countries and among women with HIV. Eliminating cervical cancer among women with HIV requires addressing both biological and social factors. There is a lack of research and evidence on cervical cancer elimination in this population, particularly in terms of HPV vaccination and its long-term effectiveness. Social and structural factors such as poverty, stigma, and gender discrimination pose challenges to the elimination strategy for cervical cancer.
Review
Pharmacology & Pharmacy
Thaina Toledo, Thales Castro, Vanessa G. Oliveira, Valdilea Goncalves Veloso, Beatriz Grinsztejn, Sandra Wagner Cardoso, Thiago S. Torres, Rita Estrela
Summary: This study aimed to systematically review the effect of aging on antiretroviral (ARV) pharmacokinetics. A total of 97 studies were included, with 20 studies involving individuals aged 50 years and older. The results showed that exposure to DRV modestly increases with age, while exposure to BIC, DOR, and RAL appears to be unaffected by age. Further studies are necessary due to the limited available evidence.
CLINICAL PHARMACOKINETICS
(2023)
Article
Health Care Sciences & Services
Angel B. Algarin, Yancheng Li, Ronald A. Cohen, Christa L. Cook, Babette Brumback, Robert L. Cook, Gladys E. Ibanez
Summary: This study found an association between HIV-related stigma and goal characteristics among people living with HIV, suggesting the need to develop interventions tailored to improve goal characteristics in the face of HIV-related stigma to enhance overall quality of life.
QUALITY OF LIFE RESEARCH
(2021)
Article
Public, Environmental & Occupational Health
Barbara N. Harding, Tigran Avoundjian, Susan R. Heckbert, Bridget M. Whitney, Robin M. Nance, Stephanie A. Ruderman, Rizwan Kalani, David L. Tirschwell, Emily L. Ho, Kyra J. Becker, Joseph Zunt, Felicia Chow, Andrew Huffer, W. Christopher Mathews, Joseph Eron, Richard D. Moore, Christina M. Marra, Greer Burkholder, Michael S. Saag, Mari M. Kitahata, Heidi M. Crane, Joseph C. Delaney
Summary: Recent findings suggest that elevated HIV viral load may be associated with an increased risk of stroke among individuals living with HIV. Particularly, high baseline viral load is significantly associated with increased risk of both ischemic and hemorrhagic stroke, while cumulative viral load shows no association with stroke risk.
Article
Multidisciplinary Sciences
Ewa Gruszczynska, Marcin Rzeszutek
Summary: The study examines the relationship between sociodemographic factors and HIV/AIDS stigma among people living with HIV. A total of 663 adults with HIV infection and undergoing antiretroviral treatment were surveyed. The findings show that heterosexual individuals have higher levels of overall stigma compared to those with other sexual orientations. Significant results were found only for disclosure concerns. Heterosexual women reported the highest level of disclosure stigma, while this relationship was not observed for men.
SCIENTIFIC REPORTS
(2023)
Article
Virology
Binita Basukala, Sarah Rossi, Sally Bendiks, Natalia Gnatienko, Gregory Patts, Evgeny Krupitsky, Dmitry Lioznov, Kaku So-Armah, Manish Sagar, Christine Cheng, Andrew J. Henderson
Summary: Among 12 million people worldwide who inject drugs, 13% are living with HIV. The impact of opioid use on HIV pathogenesis and latency remains a question. This study found no differences in intact and defective HIV proviral genomes between HIV-positive individuals with and without opioid use. However, opioid use was associated with a smaller reversible reservoir of latently infected cells, suggesting an indirect modulation of the HIV reservoir by opioids on general immune functions.
Article
Cardiac & Cardiovascular Systems
Lan Gao, Dieu Nguyen, Marj Moodie, Angela Brennan, Diem Dinh, Christopher Reid, Stephen J. Duffy, David J. Clark, Chin Hiew, Ernesto Qqueli, Dion Stub, Andrew Ajani
Summary: The long-term impact of percutaneous coronary intervention (PCI) on survival in an Australian PCI cohort remains unclear. A study found that the remaining life expectancy of PCI patients remained relatively stable over the past decade, except for the period from 2014 to 2016. Improved disease management after PCI is recommended to reduce residual mortality risk and extend the survival of patients with coronary heart disease.
AMERICAN JOURNAL OF CARDIOLOGY
(2023)
Letter
Medicine, General & Internal
Ingrid T. Katz, David E. Shapiro, Ruth Tuomala
ANNALS OF INTERNAL MEDICINE
(2015)
Article
Medicine, General & Internal
Ingrid T. Katz, Erin Leister, Deborah Kacanek, Michael D. Hughes, Arlene Bardeguez, Elizabeth Livingston, Alice Stek, David E. Shapiro, Ruth Tuomala
ANNALS OF INTERNAL MEDICINE
(2015)
Article
Public, Environmental & Occupational Health
Ingrid T. Katz, Laura M. Bogart, Chong Min Fu, Yingna Liu, Joanne E. Cox, Ronald C. Samuels, Tami Chase, Pamela Schubert, Mark A. Schuster
Article
Infectious Diseases
Ingrid T. Katz, David R. Bangsberg
CURRENT HIV/AIDS REPORTS
(2016)
Editorial Material
Medicine, General & Internal
Ingrid T. Katz, Alexi A. Wright
NEW ENGLAND JOURNAL OF MEDICINE
(2017)
Article
Multidisciplinary Sciences
Jacob Bor, Shahira Ahmed, Matthew P. Fox, Sydney Rosen, Gesine Meyer-Rath, Ingrid T. Katz, Frank Tanser, Deenan Pillay, Till Baernighausen
Article
Medicine, General & Internal
Ingrid T. Katz, Richard Kaplan, Garrett Fitzmaurice, Dominick Leone, David R. Bangsberg, Linda-Gail Bekker, Catherine Orrell
Review
Immunology
Maria F. Nardell, Oluwatomi Adeoti, Carson Peters, Bernard Kakuhikire, Caroline Govathson-Mandimika, Lawrence Long, Sophie Pascoe, Alexander C. Tsai, Ingrid T. Katz
Summary: Men are missing along the HIV care continuum in sub-Saharan Africa, with varying proportions meeting the UNAIDS 95-95-95 goals. This study estimated the proportions of men meeting each goal, described the heterogeneity, and summarized qualitative evidence on factors influencing care engagement.
JOURNAL OF THE INTERNATIONAL AIDS SOCIETY
(2022)
Article
Public, Environmental & Occupational Health
Ingrid T. Katz, Kenneth Ngure, Kevin Kamolloh, Vallery Ogello, Moses Okombo, Nicholas B. Thuo, Esther Owino, Lindsey E. Garrison, Yeonsoo S. Lee, Maria F. Nardell, Chiemelie Anyacheblu, Elizabeth Bukusi, Nelly Mugo, Jared M. Baeten, Jessica E. Haberer
Summary: This study aimed to understand why young, high-risk women in Kenya chose not to enroll in a PrEP adherence trial. The findings suggest that social norms and moral beliefs are the main barriers preventing women from accepting PrEP. To increase PrEP uptake among young Kenyan women, approaches addressing social norms and de-medicalizing HIV prevention services are needed.
Article
Public, Environmental & Occupational Health
Ingrid T. Katz, Laura M. Bogart, Garrett M. Fitzmaurice, Vincent S. Staggs, Marya V. Gwadz, Ingrid V. Bassett, Anna Cross, Ingrid Courtney, Lungiswa Tsolekile, Regina Panda, Sonja Steck, David R. Bangsberg, Catherine Orrell, Kathy Goggin
Summary: The novel pilot randomized controlled trial of the Treatment Ambassador Program (TAP) in South Africa showed high acceptability and feasibility among people with HIV not on antiretroviral therapy (ART). Results indicated a significantly higher ART initiation rate in the intervention group compared to the control group at 3 months, suggesting the effectiveness of TAP in supporting ART initiation among PWH.
Article
Psychology, Clinical
Valerie A. Earnshaw, Laura M. Bogart, Michael Klompas, Ingrid T. Katz
JOURNAL OF HEALTH PSYCHOLOGY
(2019)
Article
Psychology, Clinical
Jessica F. Magidson, Janan Dietrich, Kennedy N. Otwombe, Kathleen J. Sikkema, Ingrid T. Katz, Glenda E. Gray
JOURNAL OF HEALTH PSYCHOLOGY
(2017)
Article
Health Policy & Services
Kristin L. Johnson, Meng-Yun Lin, Howard Cabral, Lewis E. Kazis, Ingrid T. Katz
JOURNAL OF COMMUNITY HEALTH
(2017)
Article
Public, Environmental & Occupational Health
Brian C. Zanoni, Moherndran Archary, Sarah Buchan, Ingrid T. Katz, Jessica E. Haberer
