N-Acetylcysteine’s Role in Sepsis and Potential Benefit in Patients With Microcirculatory Derangements

Emerging drugs for the treatment of sepsis

(2016) Nicholas Heming et al.   EXPERT OPINION ON EMERGING DRUGS

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

(2016) Mervyn Singer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Hemodynamic Management of Septic Shock

(2015) Bernd Saugel et al.   SHOCK

Rethinking Antioxidants in the Intensive Care Unit

(2013) Manu Jain et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Heme Oxygenase-1: A Metabolic Nike

(2013) Barbara Wegiel et al.   ANTIOXIDANTS & REDOX SIGNALING

The chemistry and biological activities of N-acetylcysteine

(2013) Yuval Samuni et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Microcirculatory Alterations in Patients With Severe Sepsis

(2013) Daniel De Backer et al.   CRITICAL CARE MEDICINE

Severe abnormalities in microvascular perfused vessel density are associated to organ dysfunctions and mortality and can be predicted by hyperlactatemia and norepinephrine requirements in septic shock patients

(2013) Glenn Hernandez et al.   JOURNAL OF CRITICAL CARE

N-acetylcysteine prevents pulmonary edema and acute kidney injury in rats with sepsis submitted to mechanical ventilation

(2012) Renata Campos et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Effect of N-acetylcysteine (NAC) on acute lung injury and acute kidney injury in hemorrhagic shock

(2012) Jin Hee Lee et al.   RESUSCITATION

Effect of N-acetylcysteine treatment on oxidative stress and inflammation after severe burn

(2011) C. Csontos et al.   BURNS

The Effects of N-Acetylcysteine and Deferoxamine on Plasma Cytokine and Oxidative Damage Parameters in Critically Ill Patients With Prolonged Hypotension: A Randomized Controlled Trial

(2011) Cassiana Mazon Fraga et al.   JOURNAL OF CLINICAL PHARMACOLOGY

The effect of N-acetyl cysteine on serum glutathione, TNF-α and tissue malondialdehyde levels in the treatment of sepsis

(2011) Mehmet Gul et al.   Ulusal Travma ve Acil Cerrahi Dergisi-Turkish Journal of Trauma & Emergency Surgery

Effect of N-Acetylcysteine and Fructose-1,6-Bisphosphate in the Treatment of Experimental Sepsis

(2010) Ricardo Obalski de Mello et al.   INFLAMMATION

Pivotal role of glutathione depletion in plasma-induced endothelial oxidative stress during sepsis

(2009) Olivier Huet et al.   CRITICAL CARE MEDICINE

Protective Effects ofN-Acetylcysteine and β -Glucan Pretreatment on Oxidative Stress in Cecal Ligation and Puncture Model of Sepsis

(2009) N. Senoglu et al.   JOURNAL OF INVESTIGATIVE SURGERY

N-acetylcysteine for antioxidant therapy: pharmacology and clinical utility

(2008) Seetal Dodd et al.   EXPERT OPINION ON BIOLOGICAL THERAPY