Review
Clinical Neurology
Patricia Soblechero-Martin, Andrea Lopez-Martinez, Laura de la Puente-Ovejero, Ainara Vallejo-Illarramendi, Virginia Arechavala-Gomeza
Summary: Utrophin is a paralogue of dystrophin that can be overexpressed in the absence of dystrophin and may act as a surrogate to compensate for its deficiency. Various strategies to overexpress utrophin are being investigated, with many compounds showing promising results in preclinical studies by modulating utrophin expression and ameliorating the disease phenotype in animal models.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Stephanie Hilton, Matthias Christen, Thomas Bilzer, Vidhya Jagannathan, Tosso Leeb, Urs Giger
Summary: This study describes a clinically mild and slowly progressive muscular dystrophy in a family of Maine Coon crossbred cats. The cats exhibit marked structural changes in their muscles, but protein modeling suggests that the identified gene variant may not have a major impact on protein function.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Clinical Neurology
Carlos Pascual-Morena, Vicente Martinez-Vizcaino, Alicia Saz-Lara, Jose Francisco Lopez-Gil, Jaime Fernandez-Bravo-Rodrigo, Ivan Cavero-Redondo
Summary: Dystrophin alterations in Becker and Duchenne muscular dystrophies are associated with an increased risk of epilepsy. This study aimed to estimate the prevalence of epilepsy in BMD and DMD populations and explore the association between dystrophin gene mutation site and epilepsy risk. The results showed a higher prevalence of epilepsy in BMD and DMD populations compared to the general population, but no significant association was found between mutation site and epilepsy risk.
JOURNAL OF NEUROLOGY
(2022)
Article
Geriatrics & Gerontology
Christopher R. Heier, Nikki M. McCormack, Christopher B. Tully, James S. Novak, Breanne L. Newell-Stamper, Alan J. Russell, Alyson A. Fiorillo
Summary: Becker muscular dystrophy (BMD) is a genetic neuromuscular disease caused by mutations in the dystrophin gene. Unlike Duchenne muscular dystrophy, BMD is less severe. However, there is a lack of research and treatment options for BMD, partly due to the absence of a mouse model.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2023)
Article
Public, Environmental & Occupational Health
Yanan Zhang, Joshua R. Mann, Katherine A. James, Suzanne McDermott, Kristin M. Conway, Pangaja Paramsothy, Tiffany Smith, Bo Cai
Summary: This study examined the prevalence of Duchenne and Becker muscular dystrophies (DBMD) among males aged 5-9 years by race/ethnicity and compared the performance of three prevalence estimation methods. Results showed variability in prevalence among different racial/ethnic groups, with different methods producing similar estimates but varying confidence intervals and zero prevalence estimates.
Review
Rehabilitation
Carlos Pascual-Morena, Ivan Cavero-Redondo, Sara Reina-Gutierrez, Alicia Saz-Lara, Jose Francisco Lopez-Gil, Vicente Martinez-Vizcaino
Summary: This study aimed to estimate the prevalence of neuropsychiatric disorders among patients with Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD). The results showed that the prevalence of autism spectrum disorders (ASDs), attention-deficit hyperactivity disorder (ADHD), depression, anxiety disorders, and obsessive-compulsive disorder (OCD) was higher in DMD and BMD patients compared to the general population. The presence of these disorders may have a negative impact on optimal medical management.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2022)
Article
Clinical Neurology
Rieza H. Soelaeman, Michael G. Smith, Kashika Sahay, J. Mick Tilford, Dana Goodenough, Pangaja Paramsothy, Lijing Ouyang, Joyce Oleszek, Scott D. Grosse
Summary: This study estimated the productivity costs of caregivers of boys with Duchenne and Becker muscular dystrophies, finding that female caregivers, especially those caring for non-ambulatory boys with Duchenne muscular dystrophy, face significant financial burdens, leading to household budget constraints. Failure to include informal care costs in economic studies may underestimate the societal cost-effectiveness of strategies for managing DMD.
Review
Cardiac & Cardiovascular Systems
Chrysanthos Grigoratos, Alberto Aimo, Andrea Barison, Vincenzo Castiglione, Giancarlo Todiere, Giulia Ricci, Gabriele Siciliano, Michele Emdin
Summary: Muscular dystrophies are a group of inherited disorders with Duchenne muscular dystrophy as the most common form in childhood. Although cardiac magnetic resonance studies have largely been conducted at single centers and with small patient populations, they have provided detailed insights into cardiac involvement patterns in muscular dystrophy, leading to practical recommendations for patient management and diagnosis.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2021)
Article
Geriatrics & Gerontology
Brenda L. Wong, Suzanne Summer, Paul S. Horn, Meilan M. Rutter, Irina Rybalsky, Cuixia Tian, Karen C. Shellenbarger, Heidi J. Kalkwarf
Summary: Mutations in the dystrophin gene result in varying clinical severity of DMD, and certain indices such as ALM and ALMI may serve as potential markers for evaluating the severity of the disease and informing clinical care decisions and trial designs.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2023)
Review
Genetics & Heredity
Elizabeth A. Ulm, Chinmayee B. Nagaraj, Cuixia Tian, Teresa A. Smolarek
Summary: This study reported a rare case of biallelic DMD variants in a female and discussed the characteristics of the mild BMD phenotype caused by DMD exon 49-51 deletion, as well as the importance of genetic counseling.
MOLECULAR GENETICS & GENOMIC MEDICINE
(2023)
Article
Multidisciplinary Sciences
Nikki M. Mccormack, Nhu Y. Nguyen, Christopher B. Tully, Trinitee Oliver, Alyson A. Fiorillo, Christopher R. Heier
Summary: There is no approved therapy for Becker muscular dystrophy (BMD), a genetic muscle disease caused by in-frame dystrophin deletions. Vamorolone, a dissociative corticosteroid, shows efficacy in improving grip strength and muscle phenotypes in the BMD mouse model, with improved safety compared to prednisolone. Vamorolone also increases dystrophin protein levels in both heart and skeletal muscle, suggesting its potential as a treatment for BMD.
Review
Biochemistry & Molecular Biology
Krzysztof Zablocki, Dariusz C. Gorecki
Summary: Muscular dystrophies are inherited neuromuscular diseases that cause progressive disability and can reduce life expectancy. Loss of dystrophin or mutations in sarcoglycan-encoding genes lead to the loss of a-sarcoglycan ecto-ATPase activity, disrupting purinergic signaling and causing chronic inflammation in dystrophic muscles. Over-activation of P2X7 purinoceptors exacerbates pathology in dystrophic muscle cells. Blocking P2X7 receptors has shown promising results in mouse models and should be considered for the treatment of muscular dystrophies.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Biochemistry & Molecular Biology
Martina Sandona, Giorgia Cavioli, Alessandra Renzini, Alessia Cedola, Giuseppe Gigli, Dario Coletti, Timothy A. McKinsey, Viviana Moresi, Valentina Saccone
Summary: Histone deacetylases (HDACs) regulate the deacetylation of proteins, affecting cellular processes. Abnormal HDAC expression or activity is associated with various pathologies, making them potential therapeutic targets. For example, HDAC inhibitors have shown positive effects in preclinical and clinical studies for Duchenne Muscular Dystrophy (DMD). Understanding the cellular functions of HDACs in dystrophic muscles provides new insights for the development of effective therapeutic approaches.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Behavioral Sciences
Amanda Ferrero, Marta Rossi
Summary: This article reviews the research on cognitive, behavioral and psychosocial functioning of BMD patients. It found that BMD patients commonly experience cognitive impairment and emotional/behavioral disorders, and the lack of specific proteins can lead to intellectual disability and other brain-related comorbidities.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2022)
Review
Clinical Neurology
Mengyuan Chang, Yong Cai, Zihui Gao, Xin Chen, Boya Liu, Cheng Zhang, Weiran Yu, Qianqian Cao, Yuntian Shen, Xinlei Yao, Xiaoyang Chen, Hualin Sun
Summary: Duchenne muscular dystrophy (DMD) is a severe and progressive muscle-wasting disease, characterized by deterioration of skeletal muscle and loss of mobility. The failure of respiratory and cardiac muscles is the main cause of premature death in most DMD patients. Dystrophin deficiency, caused by mutations in the dystrophin gene, plays a crucial role in the pathogenesis of DMD, leading to muscle cell damage and dysfunction.
JOURNAL OF NEUROLOGY
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Chet R. Villa, David L. S. Morales
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Andrea Girnius, Dominica Zentner, Anne Marie Valente, Petronella G. Pieper, Katherine E. Economy, Magalie Ladouceur, Jolien W. Roos-Hesselink, Carri Warshak, Sara L. Partington, Zhiqian Gao, Nicholas Ollberding, Michelle Faust, Saulius Girnius, Harald Kaemmerer, Nicole Nagdyman, Scott Cohen, Mary Canobbio, Teiji Akagi, Jasmine Grewal, Elisa Bradley, Yonathan Buber, Joseph Palumbo, Niki Walker, Jamil Aboulhosn, Erwin Oechslin, Helmut Baumgartner, Wesam Kurdi, Wendy M. Book, Barbara J. M. Mulder, Gruschen R. Veldtman
Summary: This study evaluated thrombosis and bleeding risk in pregnant women with Fontan. Current antithrombotic strategies effectively attenuate thrombotic risk, but come with a high (>30%) bleeding risk, especially 13% being severe. Achieving haemostatic balance is challenging in pregnant women with Fontan.
Article
Critical Care Medicine
David Cooper, Ravi Thiagarajan, Brandon Michael Henry, Jonathan W. Byrnes, Andrew Misfeldt, Jason Frischer, Eileen King, Zhiqian Gao, Peter Rycus, Bradley S. Marino
Summary: This study found that the outcomes of multiple runs of ECMO remain poor. Survival decreases with each additional run. Patients requiring additional runs for pulmonary indications should be considered prime candidates. Renal complications on the first run significantly increase the risk of mortality on subsequent runs.
JOURNAL OF INTENSIVE CARE MEDICINE
(2022)
Article
Pediatrics
Stephanie Y. Tseng, Zhiqian Gao, Theodosia A. Kalfa, Nicholas J. Ollberding, Sammy Tabbah, Regina Keller, James F. Cnota
Summary: Term newborns with congenital heart disease demonstrated altered erythropoiesis at birth, characterized by decreased hemoglobin levels despite red blood cell indices consistent with stress erythropoiesis. These alterations were not associated with outcomes of fetal growth or Doppler patterns.
PEDIATRIC RESEARCH
(2022)
Article
Cardiac & Cardiovascular Systems
Chet Villa, Scott R. Auerbach, Neha Bansal, Brian F. Birnbaum, Jennifer Conway, Paul Esteso, Katheryn Gambetta, E. Kevin Hall, Beth D. Kaufman, Sonya Kirmani, Ashwin K. Lal, Hugo R. Martinez, Deipanjan Nandi, Matthew J. O'Connor, John J. Parent, Frank J. Raucci, Renata Shih, Svetlana Shugh, Jonathan H. Soslow, Hari Tunuguntla, Carol A. Wittlieb-Weber, Kathi Kinnett, Linda Cripe
Summary: This survey reveals significant variations in the diagnostic and therapeutic approaches to cardiac care in Duchenne muscular dystrophy, particularly in using advanced therapies.
PEDIATRIC CARDIOLOGY
(2022)
Article
Pediatrics
Nara S. Higano, Alister J. Bates, Chamindu C. Gunatilaka, Erik B. Hysinger, Paul J. Critser, Russel Hirsch, Jason C. Woods, Robert J. Fleck
Summary: Bronchopulmonary dysplasia (BPD) is a common long-term complication of preterm birth. Over the years, the appearance and survivability indicated by chest radiograph have evolved due to advancements in ventilation and clinical strategies. CT and MRI techniques can noninvasively evaluate comorbidities of tracheobronchomalacia and pulmonary hypertension, providing a detailed assessment of the lungs, trachea, and to some extent the heart.
PEDIATRIC RADIOLOGY
(2022)
Editorial Material
Critical Care Medicine
Nara S. Higano, Deep B. Gandhi, Qiwei Xiao, Chamindu C. Gunatilaka, Erik B. Hysinger, Robert J. Fleck, Jason C. Woods, Alister J. Bates
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Faizeen Zafar, Adam M. Lubert, Andrew T. Trout, David A. Katz, Joseph J. Palermo, Alexander R. Opotowsky, Angela Lorts, Clifford Chin, Adam W. Powell, Chet R. Villa, Nadeem Anwar, David L. Morales, Jonathan R. Dillman, Tarek Alsaied
Summary: This study aimed to determine the prevalence of radiologic evidence of portal hypertension in children and adults with Fontan circulation and its association with hemodynamics and adverse outcomes. The study found that portal hypertension was associated with an increased risk for Fontan deterioration.
Article
Cardiac & Cardiovascular Systems
Nicholas A. Szugye, Ryan A. Moore, Alia Dani, Nicholas J. Ollberding, Chet Villa, Angela Lorts, Jonathan D. Plasencia, Michael D. Taylor, David L. S. Morales, Farhan Zafar
Summary: In pediatric heart transplantation, the size matching between donor and recipient has traditionally been based on the donor:recipient weight ratio (DRWR). However, a new method based on total cardiac volume (TCV) has emerged to more precisely determine the upper limit of donor organ size while minimizing risks from oversizing. This study aims to investigate the relationship between DRWR, donor:recipient volume ratio (DRVR), and the risk of postoperative complications from allograft oversizing.
JOURNAL OF HEART AND LUNG TRANSPLANTATION
(2022)
Article
Cardiac & Cardiovascular Systems
Waldemar F. Carlo, Luz A. Padilla, Wenyuan Xu, Michael P. Carboni, Jake A. Kleinmahon, Joshua P. Sparks, Rama Rudraraju, Chet R. Villa, Tajinder P. Singh
Summary: Black race and socioeconomic disadvantage are associated with late HC rejection and graft loss in children receiving ATG induction.
JOURNAL OF HEART AND LUNG TRANSPLANTATION
(2022)
Correction
Pediatrics
Nara S. Higano, Alister J. Bates, Chamindu C. Gunatilaka, Erik B. Hysinger, Paul J. Critser, Russel Hirsch, Jason C. Woods, Robert J. Fleck
PEDIATRIC RADIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Jennifer Conway, Sandar Min, Chet Villa, Robert G. Weintraub, Stephanie Nakano, Justin Godown, Mark Tatangelo, Kathryn Armstrong, Marc Richmond, Beth Kaufman, Ashwin K. Lal, Seshadri Balaji, Alyssa Power, Nathanya Baez Hernandez, Letizia Gardin, Paul F. Kantor, John J. Parent, Peter F. Aziz, John L. Jefferies, Andreea Dragulescu, Aamir Jeewa, Lee Benson, Mark W. Russell, Robert Whitehill, Joseph Rossano, Taylor Howard, Seema Mital
Summary: This study found that abnormal exercise response in pediatric patients with hypertrophic cardiomyopathy (HCM) is associated with adverse outcomes. It suggests that exercise testing in childhood HCM can be helpful for risk assessment.
Article
Cardiac & Cardiovascular Systems
Jason W. Greenberg, Roosevelt Bryant, Chet Villa, Katrina Fields, Francis Fynn-Thompson, Farhan Zafar, David L. S. Morales
Summary: Children of minority race and ethnicity experience inferior outcomes postheart transplantation (HTx). Studies have associated ventricular assist device (VAD) bridge-to-transplant (BTT) with similar-to-superior post-transplant-survival (PTS) compared to no mechanical circulatory support. It is unclear whether racial and ethnic discrepancies exist in VAD utilization and outcomes.
JOURNAL OF HEART AND LUNG TRANSPLANTATION
(2023)
Article
Engineering, Biomedical
Sarah E. Fahnhorst, Katie Brandewie, Tanya Perry, Alexander R. Opotowsky, Adam M. Lubert, Angela Lorts, David L. S. Morales, Chet R. Villa
Summary: This study retrospectively reviewed the use of durable, continuous flow single ventricular assist device (SVAD) therapy in Fontan circulatory failure patients. The findings suggest that continuous flow SVAD therapy can be effective for patients with Fontan circulatory failure and systolic dysfunction, serving as a bridge to candidacy or temporary support before transplantation.
Article
Cardiac & Cardiovascular Systems
David A. Katz, Zhiqian Gao, Joshua Freytag, Arjun Mahendran, Cassandra Szugye, Shalayna Woodly, T. Christine E. Alvarez, Adam M. Lubert, Tarek Alsaied, Stuart L. Goldstein, Alexander R. Opotowsky
Summary: In this study, it was found that using Cystatin C-estimated glomerular filtration rate (eGFR) can more frequently detect chronic kidney disease, and urine kidney injury biomarkers also increase with declining Fontan physiological features.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Jose E. Exaire, Timothy A. Mixon
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Giuseppe Di Gioia, Federica Coletti, Lorenzo Buzzelli, Viviana Maestrini, Sara Monosilio, Andrea Segreti, Maria Rosaria Squeo, Erika Lemme, Antonio Nenna, Antonio Pelliccia
Summary: Dyslipidemia is common in Paralympic athletes, with lipid levels influenced by the type of disability and sporting discipline.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Esra Donmez, Sevgi Ozcan, Irfan Sahin, Murat Ziyrek, Ertugrul Okuyan
Summary: This study aimed to evaluate the predictive value of the GRACE risk score in acute pulmonary embolism (PE) patients for 30-day mortality and the need for thrombolytic treatment. The study found that the GRACE risk score, along with the PESI score, were independent risk factors associated with 30-day mortality and the need for thrombolytic treatment. The GRACE risk score showed high sensitivity and specificity in predicting mortality, and its combination with the PESI score helped define high-risk PE patients and predict poor prognosis.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Tom Kai Ming Wang, Reza Reyaldeen, Kevser Akyuz, Zoran B. Popovic, A. Marc Gillinov, Bo Xu, Brian P. Griffin, Milind Y. Desai
Summary: Transthoracic echocardiography (TTE) is commonly used to evaluate isolated tricuspid regurgitation (TR), but there is limited research comparing its quantification with magnetic resonance imaging (MRI). In this study, a novel TTE algorithm was developed to identify severe TR based on TTE parameters. The algorithm had a higher accuracy than the current guidelines' criteria in detecting severe TR by MRI.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Editorial Material
Cardiac & Cardiovascular Systems
Enkhtsogt Sainbayar, Ramzi Ibrahim, Hoang Nhat Pham, Wisam Beauti, Mahek Shahid, Natalie Hickerson, Mohammed Salih, Joao Paulo Ferreira, Mamas A. Mamas
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Richard E. Casazza, Hymie Chera, Carlos Adolfo Rodriguez, Sergey Ayzenberg
Summary: This article presents a case of a patient with known situs inversus who underwent cardiac catheterization and was found to have chronic total occlusion in the right coronary artery. Situs inversus is a rare congenital abnormality characterized by the inverted position of chest and abdominal organs. Cardiac catheterization is uncommon in patients with this particular abnormality, highlighting the importance of customizing techniques to engage coronary arteries and optimize guide support for percutaneous coronary intervention if needed.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Editorial Material
Cardiac & Cardiovascular Systems
Georgiana Pintea Bentea, Brahim Berdaoui, Sophie Samyn, Marielle Morissens, Philippe van de Borne, Jose Castro Rodriguez
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Bulbul Ahmed, Melissa G. Farb, Shakun Karki, Sophia D'Alessandro, Niloo M. Edwards, Noyan Gokce
Summary: This study evaluated the angiogenic capacity of adipose tissue in patients undergoing cardiac surgeries and found that patients with coronary artery disease (CAD) had reduced angiogenic capacity in their pericardial adipose tissue. Gene expression analysis revealed upregulated expression of the anti-angiogenic gene TSP-1 in CAD patients, with no significant differences in other angiogenic factors. Additionally, inhibiting TSP-1 expression significantly improved angiogenic deficiency in CAD patients.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Moshe Rav-Acha, Orli Wube, Oholi Tovia Brodie, Yoav Michowitz, Michael Ilan, Tal Ovdat, Robert Klempfner, Mahmud Suleiman, Ilan Goldenberg, Michael Glikson
Summary: The current guidelines recommend prophylactic implantable cardioverter-defibrillator (ICD) for patients with symptomatic heart failure (HF) and low left ventricular ejection fraction. However, not all patients will benefit from ICD treatment. This study evaluated the feasibility of using the MADIT-II-based Risk Stratification Score (MRSS) to predict the survival benefit of prophylactic ICDs in patients with HF. The results showed that different risk subgroups had varying levels of ICD survival benefit.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Ariel Banai, Rachel Retsky, Lior Lupu, Erez Levi, David Zahler, Omri Feder, Roei Merin, Yan Topilsky, Raphael Rosso, Shmuel Banai, Sami Viskin, Ehud Chorin
Summary: This study aims to evaluate the association between electromechanical window (EMW) and ventricular tachyarrhythmias in patients with Takotsubo syndrome (TTS). The study found that TTS patients had a lower EMW value, which was associated with an increased risk of ventricular tachyarrhythmias.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Harun Kundi, Kobina Hagan, Tamer Yahya, Garima Sharma, Sadeer Al-Kindi, Zulqarnain Javed, Khurram Nasir
Summary: Using latent class analysis (LCA), the study identified clinical, demographic, and social subphenotypes in ASCVD population and assessed the risk of all-cause and cardiovascular mortality across different socioclinical classes. The results showed that the younger, female, non-Hispanic Black or Hispanic individuals with a high burden of co-morbidities and unfavorable social determinants of health had the highest risk of mortality in the identified latent classes.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Moises A. Vasquez, Mina Iskander, Mohammed Mustafa, Juan A. Quintero-Martinez, Antonio Luna, Joel Mintz, Jose Noy, Juan Uribe, Ivan Mijares, Eduardo de Marchena, Yiannis S. Chatzizisis
Summary: The benefits of pericardiocentesis (PC) in patients with pulmonary hypertension (PH) and pericardial effusions are unclear. The study found that PC in PH patients is associated with higher in-hospital mortality and rates of cardiovascular complications.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Ken Kuwajima, Mana Ogawa, Irving Ruiz, Hiroko Hasegawa, Nobuichiro Yagi, Florian Rader, Robert J. Siegel, Takahiro Shiota
Summary: After cardiac surgery, the longitudinal function of the right ventricle and left ventricle is reduced, despite preserved global functions. In particular, tricuspid annular plane systolic excursion (TAPSE) remains decreased after surgery.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Min -Jung Kim, Robert H. Aseltine Jr, Sara R. Tabtabai
Summary: This study evaluated the rates and causes of 30-day readmissions after discharge for heart failure (HF) as a primary and secondary diagnosis. The findings indicate that efforts to reduce readmission rates should include patients with secondary HF diagnosis, and surveillance should extend to 2 weeks postdischarge to identify at-risk patients.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Ya He, Jianzhong Zhou
Summary: This study aimed to examine the relation between reverse septal curvature (RSC) and nonsustained ventricular tachycardia (NSVT) in patients with hypertrophic cardiomyopathy (HCM). The study found that patients with RSC were younger and had a higher incidence of NSVT, and RSC was identified as a strong independent risk factor for NSVT.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)