PI3Kδ Inhibition Enhances the Antitumor Fitness of Adoptively Transferred CD8+ T Cells
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
PI3Kδ Inhibition Enhances the Antitumor Fitness of Adoptively Transferred CD8+ T Cells
Authors
Keywords
-
Journal
Frontiers in Immunology
Volume 8, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2017-09-29
DOI
10.3389/fimmu.2017.01221
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Phase 1 studies of central memory-derived CD19 CAR T-cell therapy following autologous HSCT in patients with B-cell NHL
- (2016) X. Wang et al. BLOOD
- Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming
- (2016) Michael D. Buck et al. CELL
- Clinical and immunologic phenotype associated with activated phosphoinositide 3-kinase δ syndrome 2: A cohort study
- (2016) Elodie Elkaim et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Phosphatidylinositol 3-Kinase p110δ Isoform Regulates CD8+T Cell Responses during Acute Viral and Intracellular Bacterial Infections
- (2016) Donald T. Gracias et al. JOURNAL OF IMMUNOLOGY
- Memory T cell–driven differentiation of naive cells impairs adoptive immunotherapy
- (2015) Christopher A. Klebanoff et al. JOURNAL OF CLINICAL INVESTIGATION
- PI3Kδ Regulates the Magnitude of CD8+T Cell Responses after Challenge withListeria monocytogenes
- (2015) Verity Q. Pearce et al. JOURNAL OF IMMUNOLOGY
- Chimeric antigen receptor-modified T cells derived from defined CD8+ and CD4+ subsets confer superior antitumor reactivity in vivo
- (2015) D Sommermeyer et al. LEUKEMIA
- Effector CD8+ T-cell Engraftment and Antitumor Immunity in Lymphodepleted Hosts Is IL7R Dependent
- (2015) C. B. Johnson et al. Cancer Immunology Research
- Inhibition of Akt signaling promotes the generation of superior tumor-reactive T cells for adoptive immunotherapy
- (2014) A. B. van der Waart et al. BLOOD
- Akt Inhibition Enhances Expansion of Potent Tumor-Specific Lymphocytes with Memory Cell Characteristics
- (2014) J. G. Crompton et al. CANCER RESEARCH
- Heterozygous splice mutation inPIK3R1causes human immunodeficiency with lymphoproliferation due to dominant activation of PI3K
- (2014) Carrie L. Lucas et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer
- (2014) Khaled Ali et al. NATURE
- voom: precision weights unlock linear model analysis tools for RNA-seq read counts
- (2014) Charity W Law et al. GENOME BIOLOGY
- Rules of engagement: distinct functions for the four class I PI3K catalytic isoforms in immunity
- (2013) Klaus Okkenhaug Annals of the New York Academy of Sciences
- Differential roles of KLF4 in the development and differentiation of CD8+ T cells
- (2013) Maksim Mamonkin et al. IMMUNOLOGY LETTERS
- Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function
- (2013) Madhusudhanan Sukumar et al. JOURNAL OF CLINICAL INVESTIGATION
- Selective Inhibition of Phosphoinositide 3-Kinase p110α Preserves Lymphocyte Function
- (2012) Lomon So et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PI3K inhibitor, GS-1101 (CAL-101), attenuates pathway signaling, induces apoptosis, and overcomes signals from the microenvironment in cellular models of Hodgkin lymphoma
- (2011) S. A. Meadows et al. BLOOD
- Th17 Cells Are Long Lived and Retain a Stem Cell-like Molecular Signature
- (2011) Pawel Muranski et al. IMMUNITY
- A human memory T cell subset with stem cell–like properties
- (2011) Luca Gattinoni et al. NATURE MEDICINE
- PI3K p110 regulates T-cell cytokine production during primary and secondary immune responses in mice and humans
- (2010) D. R. Soond et al. BLOOD
- Human effector CD8+ T cells derived from naive rather than memory subsets possess superior traits for adoptive immunotherapy
- (2010) C. S. Hinrichs et al. BLOOD
- CAL-101, a p110 selective phosphatidylinositol-3-kinase inhibitor for the treatment of B-cell malignancies, inhibits PI3K signaling and cellular viability
- (2010) B. J. Lannutti et al. BLOOD
- From Vaccines to Memory and Back
- (2010) Federica Sallusto et al. IMMUNITY
- The p110 Isoform of Phosphatidylinositol 3-Kinase Controls the Quality of Secondary Anti-Leishmania Immunity by Regulating Expansion and Effector Function of Memory T Cell Subsets
- (2010) D. Liu et al. JOURNAL OF IMMUNOLOGY
- Programming tumor-reactive effector memory CD8+ T cells in vitro obviates the requirement for in vivo vaccination
- (2009) C. A. Klebanoff et al. BLOOD
- In vivo Antitumor Activity of MEK and Phosphatidylinositol 3-Kinase Inhibitors in Basal-Like Breast Cancer Models
- (2009) K. P. Hoeflich et al. CLINICAL CANCER RESEARCH
- The p110 Isoform of Phosphatidylinositol 3-Kinase Controls Susceptibility to Leishmania major by Regulating Expansion and Tissue Homing of Regulatory T Cells
- (2009) D. Liu et al. JOURNAL OF IMMUNOLOGY
- Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells
- (2009) Luca Gattinoni et al. NATURE MEDICINE
- The nuts and bolts of AGC protein kinases
- (2009) Laura R. Pearce et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains
- (2009) C. Carpenito et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Adoptive transfer of effector CD8+ T cells derived from central memory cells establishes persistent T cell memory in primates
- (2008) Carolina Berger et al. JOURNAL OF CLINICAL INVESTIGATION
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search