The Role of Brain-Reactive Autoantibodies in Brain Pathology and Cognitive Impairment

Long-term neurodevelopmental outcome of children born to prospectively followed pregnancies of women with systemic lupus erythematosus and/or antiphospholipid syndrome

(2017) C Nalli et al.   LUPUS

Autoantibody-induced internalization of CNS AQP4 water channel and EAAT2 glutamate transporter requires astrocytic Fc receptor

(2017) Shannon R. Hinson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glucose-regulated protein 78 autoantibody associates with blood-brain barrier disruption in neuromyelitis optica

(2017) Fumitaka Shimizu et al.   Science Translational Medicine

Mechanisms of Autoantibody-Induced Pathology

(2017) Ralf J. Ludwig et al.   Frontiers in Immunology

The Diagnosis and Treatment of Autoimmune Encephalitis

(2016) Eric Lancaster   Journal of Clinical Neurology

Cognitive dysfunction in adult patients with neuromyelitis optica: a systematic review and meta-analysis

(2016) Hao Meng et al.   JOURNAL OF NEUROLOGY

Multicentre comparison of a diagnostic assay: aquaporin-4 antibodies in neuromyelitis optica

(2016) Patrick Waters et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

The search for the target antigens of multiple sclerosis, part 2: CD8+ T cells, B cells, and antibodies in the focus of reverse-translational research

(2016) Reinhard Hohlfeld et al.   LANCET NEUROLOGY

Caspr2-reactive antibody cloned from a mother of an ASD child mediates an ASD-like phenotype in mice

(2016) L Brimberg et al.   MOLECULAR PSYCHIATRY

Distinct oligoclonal band antibodies in multiple sclerosis recognize ubiquitous self-proteins

(2016) Simone M. Brändle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly encephalitogenic aquaporin 4-specific T cells and NMO-IgG jointly orchestrate lesion location and tissue damage in the CNS

(2015) Bleranda Zeka et al.   ACTA NEUROPATHOLOGICA

Maternal antibodies and developing blood–brain barrier

(2015) Czeslawa Kowal et al.   IMMUNOLOGIC RESEARCH

Cognitive impairment in Chinese neuromyelitis optica

(2015) N Zhang et al.   Multiple Sclerosis Journal

Pregnancy outcomes in aquaporin-4–positive neuromyelitis optica spectrum disorder

(2015) Matthew M. Nour et al.   NEUROLOGY

International consensus diagnostic criteria for neuromyelitis optica spectrum disorders

(2015) Dean M. Wingerchuk et al.   NEUROLOGY

Antibodies to influenza nucleoprotein cross-react with human hypocretin receptor 2

(2015) Syed Sohail Ahmed et al.   Science Translational Medicine

Antibodies as Mediators of Brain Pathology

(2015) Lior Brimberg et al.   TRENDS IN IMMUNOLOGY

Cognitive impairment in Chinese neuromyelitis optica

(2015) N Zhang et al.   Multiple Sclerosis Journal

Pathogenicity of Lupus Anti-Ribosomal P Antibodies: Role of Cross-Reacting Neuronal Surface P Antigen in Glutamatergic Transmission and Plasticity in a Mouse Model

(2015) Fabián Segovia-Miranda et al.   Arthritis & Rheumatology

Selective Impairment of Spatial Cognition Caused by Autoantibodies to the N-Methyl-d-Aspartate Receptor

(2015) Eric H. Chang et al.   EBioMedicine

Treatment of neuromyelitis optica: state-of-the-art and emerging therapies

(2014) Marios C. Papadopoulos et al.   Nature Reviews Neurology

Diagnosis and management of neuropsychiatric SLE

(2014) John G. Hanly   Nature Reviews Rheumatology

Narcolepsy patients have antibodies that stain distinct cell populations in rat brain and influence sleep patterns

(2014) P. Bergman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes

(2014) J. N. H. Stern et al.   Science Translational Medicine

The gut microbiota influences blood-brain barrier permeability in mice

(2014) V. Braniste et al.   Science Translational Medicine

Association of cerebrospinal fluid anti-Sm antibodies with acute confusional state in systemic lupus erythematosus

(2014) Shunsei Hirohata et al.   ARTHRITIS RESEARCH & THERAPY

Anti-Ribosomal P Protein Autoantibodies From Patients With Neuropsychiatric Lupus Impair Memory in Mice

(2014) Marcela Bravo-Zehnder et al.   Arthritis & Rheumatology

Presence of six different lesion types suggests diverse mechanisms of tissue injury in neuromyelitis optica

(2013) Tatsuro Misu et al.   ACTA NEUROPATHOLOGICA

Brain-Reactive Antibodies and Disease

(2013) B. Diamond et al.   Annual Review of Immunology

Cognitive performance of neuromyelitis optica patients: comparison with multiple sclerosis

(2013) Sandra Vanotti et al.   ARQUIVOS DE NEURO-PSIQUIATRIA

Experimental Models of Neuromyelitis Optica

(2013) Monika Bradl et al.   BRAIN PATHOLOGY

The Pathology of an Autoimmune Astrocytopathy: Lessons Learned from Neuromyelitis Optica

(2013) Claudia F. Lucchinetti et al.   BRAIN PATHOLOGY

Distinction and Temporal Stability of Conformational Epitopes on Myelin Oligodendrocyte Glycoprotein Recognized by Patients with Different Inflammatory Central Nervous System Diseases

(2013) M. C. Mayer et al.   JOURNAL OF IMMUNOLOGY

Neuromyelitis Optica IgG Causes Placental Inflammation and Fetal Death

(2013) S. Saadoun et al.   JOURNAL OF IMMUNOLOGY

Aquaporin 4 molecular mimicry and implications for neuromyelitis optica

(2013) Radhika A. Vaishnav et al.   JOURNAL OF NEUROIMMUNOLOGY

Update on the diagnosis and treatment of neuromyelitis optica: Recommendations of the Neuromyelitis Optica Study Group (NEMOS)

(2013) Corinna Trebst et al.   JOURNAL OF NEUROLOGY

Eculizumab in AQP4-IgG-positive relapsing neuromyelitis optica spectrum disorders: an open-label pilot study

(2013) Sean J Pittock et al.   LANCET NEUROLOGY

Brain-reactive IgG correlates with autoimmunity in mothers of a child with an autism spectrum disorder

(2013) L Brimberg et al.   MOLECULAR PSYCHIATRY

Aquaporin water channels in the nervous system

(2013) Marios C. Papadopoulos et al.   NATURE REVIEWS NEUROSCIENCE

Intrastriatal injection of interleukin-1 beta triggers the formation of neuromyelitis optica-like lesions in NMO-IgG seropositive rats

(2013) Maja Kitic et al.   Acta Neuropathologica Communications

T cell-activation in neuromyelitis optica lesions plays a role in their formation

(2013) Maria Pohl et al.   Acta Neuropathologica Communications

IgG anti-NR2 glutamate receptor autoantibodies from patients with systemic lupus erythematosus activate endothelial cells

(2012) Taku Yoshio et al.   ARTHRITIS AND RHEUMATISM

A model for lupus brain disease

(2012) Betty Diamond et al.   IMMUNOLOGICAL REVIEWS

Female mouse fetal loss mediated by maternal autoantibody

(2012) Li Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pathogenic T cell responses against aquaporin 4

(2011) Maria Pohl et al.   ACTA NEUROPATHOLOGICA

Related B cell clones that populate the CSF and CNS of patients with multiple sclerosis produce CSF immunoglobulin

(2011) Birgit Obermeier et al.   JOURNAL OF NEUROIMMUNOLOGY

Temporal dynamics of cerebrospinal fluid anti-aquaporin-4 antibodies in patients with neuromyelitis optica spectrum disorders

(2011) Irena Dujmovic et al.   JOURNAL OF NEUROIMMUNOLOGY

Neuromyelitis optica unique area postrema lesions: Nausea, vomiting, and pathogenic implications

(2011) B. F. G. Popescu et al.   NEUROLOGY

Blood-Brain Barrier Differentiation

(2011) B. Engelhardt   SCIENCE

Intra-cerebral injection of neuromyelitis optica immunoglobulin G and human complement produces neuromyelitis optica lesions in mice

(2010) Samira Saadoun et al.   BRAIN

Cerebrospinal fluid antibodies to aquaporin-4 in neuromyelitis optica and related disorders: frequency, origin, and diagnostic relevance

(2010) Sven Jarius et al.   Journal of Neuroinflammation

Cellular and Synaptic Mechanisms of Anti-NMDA Receptor Encephalitis

(2010) E. G. Hughes et al.   JOURNAL OF NEUROSCIENCE

Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis

(2010) Josep Dalmau et al.   LANCET NEUROLOGY

AQP4 antibodies in neuromyelitis optica: diagnostic and pathogenetic relevance

(2010) Sven Jarius et al.   Nature Reviews Neurology

Patterns of Antibody Binding to Aquaporin-4 Isoforms in Neuromyelitis Optica

(2010) Simone Mader et al.   PLoS One

Neurotoxic lupus autoantibodies alter brain function through two distinct mechanisms

(2010) T. W. Faust et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuromyelitis optica: Pathogenicity of patient immunoglobulin in vivo

(2009) Monika Bradl et al.   ANNALS OF NEUROLOGY

Intrathecal pathogenic anti–aquaporin-4 antibodies in early neuromyelitis optica

(2009) Jeffrey L. Bennett et al.   ANNALS OF NEUROLOGY

Prospective analysis of neuropsychiatric events in an international disease inception cohort of patients with systemic lupus erythematosus

(2009) J. G. Hanly et al.   ANNALS OF THE RHEUMATIC DISEASES

Neuromyelitis optica: Passive transfer to rats by human immunoglobulin

(2009) Makoto Kinoshita et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Neurocognitive impairment in children and adolescents with systemic lupus erythematosus

(2009) Deborah M Levy et al.   Nature clinical practice. Rheumatology

Cognitive Functions in Neuromyelitis Optica

(2008) Frédéric Blanc et al.   ARCHIVES OF NEUROLOGY

Association of cerebrospinal fluid anti-NR2 glutamate receptor antibodies with diffuse neuropsychiatric systemic lupus erythematosus

(2008) Yoshiyuki Arinuma et al.   ARTHRITIS AND RHEUMATISM

Aquaporin-4–binding autoantibodies in patients with neuromyelitis optica impair glutamate transport by down-regulating EAAT2

(2008) Shannon R. Hinson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Paraneoplastic syndromes of the CNS

(2008) Josep Dalmau et al.   LANCET NEUROLOGY

Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies

(2008) Josep Dalmau et al.   LANCET NEUROLOGY

Neurocognitive abnormalities in offspring of mothers with systemic lupus erythematosus

(2008) MB Urowitz et al.   LUPUS

Neurotoxic autoantibodies mediate congenital cortical impairment of offspring in maternal lupus

(2008) Ji Y Lee et al.   NATURE MEDICINE