The Maternal Diet, Gut Bacteria, and Bacterial Metabolites during Pregnancy Influence Offspring Asthma

Omega-3 long-chain PUFA intake during pregnancy and allergic disease outcomes in the offspring: a systematic review and meta-analysis of observational studies and randomized controlled trials

(2016) Karen P Best et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Modulation of the human gut microbiota by dietary fibres occurs at the species level

(2016) Wing Sun Faith Chung et al.   BMC BIOLOGY

Effect of Prenatal Supplementation With Vitamin D on Asthma or Recurrent Wheezing in Offspring by Age 3 Years

(2016) Augusto A. Litonjua et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Effect of Vitamin D3Supplementation During Pregnancy on Risk of Persistent Wheeze in the Offspring

(2016) Bo L. Chawes et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Diet–microbiota interactions as moderators of human metabolism

(2016) Justin L. Sonnenburg et al.   NATURE

Diet-induced extinctions in the gut microbiota compound over generations

(2016) Erica D. Sonnenburg et al.   NATURE

Breathing Easier with Fish Oil — A New Approach to Preventing Asthma?

(2016) Christopher E. Ramsden   NEW ENGLAND JOURNAL OF MEDICINE

Patterns of Growth and Decline in Lung Function in Persistent Childhood Asthma

(2016) Michael J. McGeachie et al.   NEW ENGLAND JOURNAL OF MEDICINE

Fish Oil–Derived Fatty Acids in Pregnancy and Wheeze and Asthma in Offspring

(2016) Hans Bisgaard et al.   NEW ENGLAND JOURNAL OF MEDICINE

Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children

(2016) Michelle M. Stein et al.   NEW ENGLAND JOURNAL OF MEDICINE

The maternal microbiota drives early postnatal innate immune development

(2016) M. Gomez de Aguero et al.   SCIENCE

Natural history of the infant gut microbiome and impact of antibiotic treatment on bacterial strain diversity and stability

(2016) Moran Yassour et al.   Science Translational Medicine

Intestinal microbiome is related to lifetime antibiotic use in Finnish pre-school children

(2016) Katri Korpela et al.   Nature Communications

The Probiotics in Pregnancy Study (PiP Study): rationale and design of a double-blind randomised controlled trial to improve maternal health during pregnancy and prevent infant eczema and allergy

(2016) Christine Barthow et al.   BMC Pregnancy and Childbirth

Alterations in fecal microbiota composition by probiotic supplementation in healthy adults: a systematic review of randomized controlled trials

(2016) Nadja B. Kristensen et al.   Genome Medicine

Comparison of placenta samples with contamination controls does not provide evidence for a distinct placenta microbiota

(2016) Abigail P. Lauder et al.   Microbiome

World Allergy Organization-McMaster University Guidelines for Allergic Disease Prevention (GLAD-P): Prebiotics

(2016) Carlos A. Cuello-Garcia et al.   World Allergy Organization Journal

Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites

(2015) Alison N. Thorburn et al.   Nature Communications

Diversity in gut bacterial community of school-age children in Asia

(2015) Jiro Nakayama et al.   Scientific Reports

The Gut Microbiota of Rural Papua New Guineans: Composition, Diversity Patterns, and Ecological Processes

(2015) Inés Martínez et al.   Cell Reports

Starving our Microbial Self: The Deleterious Consequences of a Diet Deficient in Microbiota-Accessible Carbohydrates

(2014) Erica D. Sonnenburg et al.   Cell Metabolism

Omega-3 Fatty Acid Supplementation During Pregnancy and Respiratory Symptoms in Children

(2014) María Consuelo Escamilla-Nuñez et al.   CHEST

Preventive effects of selected probiotic strains on the development of asthma and allergic rhinitis in childhood. The Panda study

(2014) D. M. W. Gorissen et al.   CLINICAL AND EXPERIMENTAL ALLERGY

The evolution of the hygiene hypothesis

(2014) Denise Daley   Current Opinion in Allergy and Clinical Immunology

Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis

(2014) Nagendra Singh et al.   IMMUNITY

Supplementing Pregnant Mice with a Specific Mixture of Nondigestible Oligosaccharides Reduces Symptoms of Allergic Asthma in Male Offspring

(2014) Astrid Hogenkamp et al.   JOURNAL OF NUTRITION

Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis

(2014) Aurélien Trompette et al.   NATURE MEDICINE

The Placenta Harbors a Unique Microbiome

(2014) K. Aagaard et al.   Science Translational Medicine

Gut microbiome of the Hadza hunter-gatherers

(2014) Stephanie L. Schnorr et al.   Nature Communications

Maternal propensity for infections and risk of childhood asthma: a registry-based cohort study

(2014) Jakob Stokholm et al.   Lancet Respiratory Medicine

Randomized controlled trial of fish oil supplementation in pregnancy on childhood allergies

(2013) D. J. Palmer et al.   ALLERGY

Early supplementation withLactobacillus rhamnosus HN001 reduces eczema prevalence to 6 years: does it also reduce atopic sensitization?

(2013) K. Wickens et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Fetal-Maternal Alignment of Regulatory T Cells Correlates with IL-10 and Bcl-2 Upregulation in Pregnancy

(2013) B. Santner-Nanan et al.   JOURNAL OF IMMUNOLOGY

Intestinal Epithelium-Derived Galectin-9 Is Involved in the Immunomodulating Effects of Nondigestible Oligosaccharides

(2013) Sander de Kivit et al.   Journal of Innate Immunity

The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism

(2013) Gijs den Besten et al.   JOURNAL OF LIPID RESEARCH

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

(2013) Yukihiro Furusawa et al.   NATURE

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

(2013) Nicholas Arpaia et al.   NATURE

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

No effect of probiotics on respiratory allergies: a seven-year follow-up of a randomized controlled trial in infancy

(2013) Thomas R. Abrahamsson et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis

(2013) P. M. Smith et al.   SCIENCE

Probiotic supplementation during pregnancy or infancy for the prevention of asthma and wheeze: systematic review and meta-analysis

(2013) M. B. Azad et al.   BMJ-British Medical Journal

Maternal dietary fat and fatty acid intake during lactation and the risk of asthma in the offspring

(2012) M Lumia et al.   ACTA PAEDIATRICA

Increased intake of oily fish in pregnancy: effects on neonatal immune responses and on clinical outcomes in infants at 6 mo

(2012) Paul S Noakes et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Gut Microbiota Composition and Activity in Relation to Host Metabolic Phenotype and Disease Risk

(2012) Elaine Holmes et al.   Cell Metabolism

Prenatal and postnatal probiotics reduces maternal but not childhood allergic diseases: a randomized, double-blind, placebo-controlled trial

(2012) C.-Y. Ou et al.   CLINICAL AND EXPERIMENTAL ALLERGY

The farm effect, or

(2012) Gabriela Wlasiuk et al.   Current Opinion in Allergy and Clinical Immunology

Vitamin D deficiency as a risk factor for childhood allergic disease and asthma

(2012) Augusto A. Litonjua   Current Opinion in Allergy and Clinical Immunology

Passive immunization with allergen-specific IgG antibodies for treatment and prevention of allergy

(2012) Sabine Flicker et al.   IMMUNOBIOLOGY

Early life exposure to farm animals and symptoms of asthma, rhinoconjunctivitis and eczema: an ISAAC Phase Three Study

(2012) Bert Brunekreef et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Protection from childhood asthma and allergy in Alpine farm environments—the GABRIEL Advanced Studies

(2012) Sabina Illi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Asthma as a chronic disease of the innate and adaptive immune systems responding to viruses and allergens

(2012) Michael J. Holtzman   JOURNAL OF CLINICAL INVESTIGATION

Use of Antibiotics during Pregnancy Increases the Risk of Asthma in Early Childhood

(2012) Lone Graff Stensballe et al.   JOURNAL OF PEDIATRICS

Structure, function and diversity of the healthy human microbiome

(2012)   NATURE

Human gut microbiome viewed across age and geography

(2012) Tanya Yatsunenko et al.   NATURE

Innate and adaptive immune responses in asthma

(2012) Stephen T Holgate   NATURE MEDICINE

Exposure to farming environments in childhood and asthma and wheeze in rural populations: a systematic review with meta-analysis

(2012) Jon Genuneit   PEDIATRIC ALLERGY AND IMMUNOLOGY

Host-Gut Microbiota Metabolic Interactions

(2012) J. K. Nicholson et al.   SCIENCE

Maternal intake of fatty acids during pregnancy and allergies in the offspring

(2011) Bright I. Nwaru et al.   BRITISH JOURNAL OF NUTRITION

Umbilical cord plasma 25-hydroxyvitamin D concentration and immune function at birth: the Urban Environment and Childhood Asthma study

(2011) A. Chi et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Maternal fatty acid status in pregnancy and childhood atopic manifestations: KOALA Birth Cohort Study

(2011) M. L. Notenboom et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Maternal intestinal flora and wheeze in early childhood

(2011) N. E. Lange et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Early life exposures

(2011) Anita L. Kozyrskyj et al.   Current Opinion in Allergy and Clinical Immunology

Glycan recognition at the interface of the intestinal immune system: Target for immune modulation via dietary components

(2011) Sander de Kivit et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Exposure to Environmental Microorganisms and Childhood Asthma

(2011) Markus J. Ege et al.   NEW ENGLAND JOURNAL OF MEDICINE

The GABRIEL Advanced Surveys: study design, participation and evaluation of bias

(2011) Jon Genuneit et al.   PAEDIATRIC AND PERINATAL EPIDEMIOLOGY

Allergic disease in infants up to 2 years of age in relation to plasma omega-3 fatty acids and maternal fish oil supplementation in pregnancy and lactation

(2011) Catrin Furuhjelm et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Prenatal or Early-Life Exposure to Antibiotics and Risk of Childhood Asthma: A Systematic Review

(2011) W. Murk et al.   PEDIATRICS

Perinatal programming of murine immune responses by polyunsaturated fatty acids

(2011) N. van Vlies et al.   Journal of Developmental Origins of Health and Disease

Consumption of vegetables, fruit, and antioxidants during pregnancy and wheeze and eczema in infants

(2010) Y. Miyake et al.   ALLERGY

Harnessing Regulatory T cells to Suppress Asthma

(2010) Alison N. Thorburn et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Prenatal Exposures to Persistent and Non-Persistent Organic Compounds and Effects on Immune System Development

(2010) Irva Hertz-Picciotto et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Probiotics in pregnant women to prevent allergic disease: a randomized, double-blind trial

(2010) C.K. Dotterud et al.   BRITISH JOURNAL OF DERMATOLOGY

Galectin-9 regulates T helper cell function independently of Tim-3

(2010) E. W. Su et al.   GLYCOBIOLOGY

Dominant and diet-responsive groups of bacteria within the human colonic microbiota

(2010) Alan W Walker et al.   ISME Journal

Blockade of Dendritic Cell Development by Bacterial Fermentation Products Butyrate and Propionate through a Transporter (Slc5a8)-dependent Inhibition of Histone Deacetylases

(2010) Nagendra Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Detection of ureaplasmas by the polymerase chain reaction in the amniotic fluid of patients with cervical insufficiency

(2010) Kyung Joon Oh et al.   JOURNAL OF PERINATAL MEDICINE

Long-term impacts of antibiotic exposure on the human intestinal microbiota

(2010) C. Jernberg et al.   MICROBIOLOGY-SGM

Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa

(2010) C. De Filippo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Maternal vitamin D intake during pregnancy is inversely associated with asthma and allergic rhinitis in 5-year-old children

(2009) M. Erkkola et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Regulatory T cells and asthma

(2009) D. S. Robinson   CLINICAL AND EXPERIMENTAL ALLERGY

Dairy food, calcium and vitamin D intake in pregnancy, and wheeze and eczema in infants

(2009) Y. Miyake et al.   EUROPEAN RESPIRATORY JOURNAL

Maternal farm exposure modulates neonatal immune mechanisms through regulatory T cells

(2009) Bianca Schaub et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Antibiotic use in infancy and symptoms of asthma, rhinoconjunctivitis, and eczema in children 6 and 7 years old: International Study of Asthma and Allergies in Childhood Phase III

(2009) Sunia Foliaki et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Probiotics prevent IgE-associated allergy until age 5 years in cesarean-delivered children but not in the total cohort

(2009) Mikael Kuitunen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Cord blood cytokines are modulated by maternal farming activities and consumption of farm dairy products during pregnancy: The PASTURE Study

(2009) Petra Ina Pfefferle et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

(2009) Kendle M. Maslowski et al.   NATURE

Butyrate and propionate induced activated or non-activated neutrophil apoptosis via HDAC inhibitor activity but without activating GPR-41/GPR-43 pathways

(2009) Michiko Aoyama et al.   NUTRITION

T-cell activation during exacerbations: a longitudinal study in refractory asthma

(2008) E. Mamessier et al.   ALLERGY

Determinants of the Incidence of Childhood Asthma: A Two-Stage Case-Control Study

(2008) M.-J. Martel et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Immunomodulatory effects of the intake of fermented milk with Lactobacillus casei DN114001 in lactating mothers and their children

(2008) Adriana Ortiz-Andrellucchi et al.   BRITISH JOURNAL OF NUTRITION

Impact of PUFA on early immune and fetal development

(2008) Uta Enke et al.   BRITISH JOURNAL OF NUTRITION

Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis

(2008) Masako Seki et al.   CLINICAL IMMUNOLOGY

Probiotics: Definition, Sources, Selection, and Uses

(2008) Mary Ellen Sanders   CLINICAL INFECTIOUS DISEASES

Farm exposure in utero may protect against asthma, hay fever and eczema

(2008) J. Douwes et al.   EUROPEAN RESPIRATORY JOURNAL

BifidobacteriumandLactobacillusDNA in the human placenta

(2008) R. Satokari et al.   LETTERS IN APPLIED MICROBIOLOGY

Randomized, Double-Blind, Placebo-Controlled Trial of Probiotics for Primary Prevention: No Clinical Effects of Lactobacillus GG Supplementation

(2008) M. V. Kopp et al.   PEDIATRICS

Is meconium from healthy newborns actually sterile?

(2008) Esther Jiménez et al.   RESEARCH IN MICROBIOLOGY

Allergy Takes Its Toll

(2008) Susan L. Prescott   World Allergy Organization Journal