Targeting Multiple Tumors Using T-Cells Engineered to Express a Natural Cytotoxicity Receptor 2-Based Chimeric Receptor

Tricking the balance: NK cells in anti-cancer immunity

(2017) Jens Pahl et al.   IMMUNOBIOLOGY

Novel T cells with improved in vivo anti-tumor activity generated by RNA electroporation

(2017) Xiaojun Liu et al.   Protein & Cell

The mutational status of p53 can influence its recognition by human T-cells

(2017) Katerina Shamalov et al.   OncoImmunology

Therapeutic Potential of T Cell Chimeric Antigen Receptors (CARs) in Cancer Treatment: Counteracting Off-Tumor Toxicities for Safe CAR T Cell Therapy

(2016) Gideon Gross et al.   Annual Review of Pharmacology and Toxicology

Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells

(2016) Omkar U. Kawalekar et al.   IMMUNITY

Chimeric antigen receptor-redirected T cells return to the bench

(2016) Claudia Geldres et al.   SEMINARS IN IMMUNOLOGY

Regulation of natural cytotoxicity receptors by heparan sulfate proteoglycans in -cis : A lesson from NKp44

(2015) Michael Brusilovsky et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mutant MHC class II epitopes drive therapeutic immune responses to cancer

(2015) Sebastian Kreiter et al.   NATURE

Adoptive Cell Therapy—Tumor-Infiltrating Lymphocytes, T-Cell Receptors, and Chimeric Antigen Receptors

(2015) Steven A. Feldman et al.   SEMINARS IN ONCOLOGY

NKp44 and Natural Cytotoxicity Receptors as Damage-Associated Molecular Pattern Recognition Receptors

(2015) Nathan C. Horton et al.   Frontiers in Immunology

An NCR1-based chimeric receptor endows T-cells with multiple anti-tumor specificities

(2015) Yair Tal et al.   Oncotarget

Classification of current anticancer immunotherapies

(2015) Lorenzo Galluzzi et al.   Oncotarget

Cancer Immunotherapy Based on Mutation-Specific CD4+ T Cells in a Patient with Epithelial Cancer

(2014) E. Tran et al.   SCIENCE

CD4+ T Lymphocyte Ablation Prevents Pancreatic Carcinogenesis in Mice

(2014) Y. Zhang et al.   Cancer Immunology Research

How Do CD4+ T Cells Detect and Eliminate Tumor Cells That Either Lack or Express MHC Class II Molecules?

(2014) Ole Audun Werner Haabeth et al.   Frontiers in Immunology

Does the Immune System Naturally Protect Against Cancer?

(2014) Alexandre Corthay   Frontiers in Immunology

Out of the bitter came forth sweet

(2014) Chen Ankri et al.   OncoImmunology

Identification of a cellular ligand for the natural cytotoxicity receptor NKp44

(2013) F. Baychelier et al.   BLOOD

NK cell-based immunotherapy for malignant diseases

(2013) Min Cheng et al.   Cellular & Molecular Immunology

Of CARs and TRUCKs: chimeric antigen receptor (CAR) T cells engineered with an inducible cytokine to modulate the tumor stroma

(2013) Markus Chmielewski et al.   IMMUNOLOGICAL REVIEWS

Enhanced antitumor activity mediated by human 4-1BB-engineered T cells

(2013) Inbal Daniel-Meshulam et al.   INTERNATIONAL JOURNAL OF CANCER

Activating natural cytotoxicity receptors of natural killer cells in cancer and infection

(2013) Joachim Koch et al.   TRENDS IN IMMUNOLOGY

Natural Cytotoxicity Receptors: Broader Expression Patterns and Functions in Innate and Adaptive Immune Cells

(2013) Kelly Hudspeth et al.   Frontiers in Immunology

Toward the next generation of NK cell-based adoptive cancer immunotherapy

(2013) Jing Ni et al.   OncoImmunology

An NKp30-Based Chimeric Antigen Receptor Promotes T Cell Effector Functions and Antitumor Efficacy In Vivo

(2012) T. Zhang et al.   JOURNAL OF IMMUNOLOGY

Human Antitumor CD8+ T Cells Producing Th1 Polycytokines Show Superior Antigen Sensitivity and Tumor Recognition

(2012) S. Wilde et al.   JOURNAL OF IMMUNOLOGY

Recognition and Prevention of Tumor Metastasis by the NK Receptor NKp46/NCR1

(2012) A. Glasner et al.   JOURNAL OF IMMUNOLOGY

Live and Let Die: A New Suicide Gene Therapy Moves to the Clinic

(2012) Richard A Morgan   MOLECULAR THERAPY

CAR–T cells and solid tumors: tuning T cells to challenge an inveterate foe

(2012) David E. Gilham et al.   TRENDS IN MOLECULAR MEDICINE

How (specific) would like your T-cells today? Generating T-cell therapeutic function through TCR-gene transfer

(2012) Inbal Daniel-Meshulam et al.   Frontiers in Immunology

A novel mechanism for cancer cells to evade immune attack by NK cells

(2012) Benyamin Rosental et al.   OncoImmunology

OX40 costimulation by a chimeric antigen receptor abrogates CD28 and IL-2 induced IL-10 secretion by redirected CD4+T cells

(2012) Andreas A. Hombach et al.   OncoImmunology

Redirecting   T cells against cancer cells by transfer of a broadly tumor-reactive   T-cell receptor

(2011) V. Marcu-Malina et al.   BLOOD

CD27 costimulation augments the survival and antitumor activity of redirected human T cells in vivo

(2011) D.-G. Song et al.   BLOOD

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Adoptive Transfer of Autologous Natural Killer Cells Leads to High Levels of Circulating Natural Killer Cells but Does Not Mediate Tumor Regression

(2011) M. R. Parkhurst et al.   CLINICAL CANCER RESEARCH

Treatment of multiple myeloma with adoptively transferred chimeric NKG2D receptor-expressing T cells

(2011) A Barber et al.   GENE THERAPY

Proliferating Cell Nuclear Antigen Is a Novel Inhibitory Ligand for the Natural Cytotoxicity Receptor NKp44

(2011) B. Rosental et al.   JOURNAL OF IMMUNOLOGY

Genetically modulating T-cell function to target cancer

(2011) Efrat Merhavi-Shoham et al.   SEMINARS IN CANCER BIOLOGY

Natural killer cells and cancer: Regulation by the killer cell Ig-like receptors (KIR)

(2010) Amanda K. Purdy et al.   CANCER BIOLOGY & THERAPY

Chimeric Antigen Receptor-Engineered T Cells for Immunotherapy of Cancer

(2010) Marc Cartellieri et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Distinct Roles for the NK Cell-Activating Receptors in Mediating Interactions with Dendritic Cells and Tumor Cells

(2010) L.-E. Wai et al.   JOURNAL OF IMMUNOLOGY

Tumor Immunoediting by NKp46

(2010) M. Elboim et al.   JOURNAL OF IMMUNOLOGY

Adoptive immunotherapy of cancer using CD4+ T cells

(2009) Pawel Muranski et al.   CURRENT OPINION IN IMMUNOLOGY

NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo

(2009) Tadepally Lakshmikanth et al.   JOURNAL OF CLINICAL INVESTIGATION

Chimeric NKG2D Expressing T Cells Eliminate Immunosuppression and Activate Immunity within the Ovarian Tumor Microenvironment

(2009) A. Barber et al.   JOURNAL OF IMMUNOLOGY

Recognition of NY-ESO-1+ tumor cells by engineered lymphocytes is enhanced by improved vector design and epigenetic modulation of tumor antigen expression

(2008) Jennifer A. Wargo et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Direct Binding of Human NK Cell Natural Cytotoxicity Receptor NKp44 to the Surfaces of Mycobacteria and Other Bacteria

(2008) S. Esin et al.   INFECTION AND IMMUNITY

Functions of natural killer cells

(2008) Eric Vivier et al.   NATURE IMMUNOLOGY