Calreticulin Release at an Early Stage of Death Modulates the Clearance by Macrophages of Apoptotic Cells

The C-Terminal Acidic Region of Calreticulin Mediates Phosphatidylserine Binding and Apoptotic Cell Phagocytosis

(2016) Sanjeeva Joseph Wijeyesakere et al.   JOURNAL OF IMMUNOLOGY

Agarose gel shift assay reveals that calreticulin favors substrates with a quaternary structure in solution

(2015) Sanne Grundvad Boelt et al.   ANALYTICAL BIOCHEMISTRY

Phagocytosis of apoptotic cells in homeostasis

(2015) Sanja Arandjelovic et al.   NATURE IMMUNOLOGY

Macrophages eat cancer cells using their own calreticulin as a guide: Roles of TLR and Btk

(2015) Mingye Feng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resistance to anticancer vaccination effect is controlled by a cancer cell-autonomous phenotype that disrupts immunogenic phagocytic removal

(2015) Abhishek D. Garg et al.   Oncotarget

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Murine Low-Density Lipoprotein Receptor-Related Protein 1 (LRP) Is Required for Phagocytosis of Targets Bearing LRP Ligands but Is Not Required for C1q-Triggered Enhancement of Phagocytosis

(2014) A. P. Lillis et al.   JOURNAL OF IMMUNOLOGY

Relative Contribution of C1q and Apoptotic Cell-Surface Calreticulin to Macrophage Phagocytosis

(2014) Mélanie Verneret et al.   Journal of Innate Immunity

An optimized Protocol for Human M2 Macrophages using M-CSF and IL-4/IL-10/TGF-βYields a Dominant Immunosuppressive Phenotype

(2014) S. Mia et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

The scavenger receptor SCARF1 mediates the clearance of apoptotic cells and prevents autoimmunity

(2013) Zaida G Ramirez-Ortiz et al.   NATURE IMMUNOLOGY

Clearing the Dead: Apoptotic Cell Sensing, Recognition, Engulfment, and Digestion

(2013) A. Hochreiter-Hufford et al.   Cold Spring Harbor Perspectives in Biology

Dissecting the roles of Rac1 activation and deactivation in macropinocytosis using microscopic photo-manipulation

(2013) Makoto Fujii et al.   Scientific Reports

Efficient Clearance of Early Apoptotic Cells by Human Macrophages Requires M2c Polarization and MerTK Induction

(2012) G. Zizzo et al.   JOURNAL OF IMMUNOLOGY

Complement Protein C1q Directs Macrophage Polarization and Limits Inflammasome Activity during the Uptake of Apoptotic Cells

(2012) M. E. Benoit et al.   JOURNAL OF IMMUNOLOGY

The use of THP-1 cells as a model for mimicking the function and regulation of monocytes and macrophages in the vasculature

(2011) Zhenyu Qin   ATHEROSCLEROSIS

Modulatory role of calreticulin as chaperokine for dendritic cell-based immunotherapy

(2011) A. Bajor et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Investigations on the C1q–Calreticulin–Phosphatidylserine Interactions Yield New Insights into Apoptotic Cell Recognition

(2011) Helena Païdassi et al.   JOURNAL OF MOLECULAR BIOLOGY

X-Ray Structure of the Human Calreticulin Globular Domain Reveals a Peptide-Binding Area and Suggests a Multi-Molecular Mechanism

(2011) Anne Chouquet et al.   PLoS One

Surface-exposed calreticulin in the interaction between dying cells and phagocytes

(2010) Isabelle Martins et al.   Annals of the New York Academy of Sciences

A Mechanism of Release of Calreticulin from Cells During Apoptosis

(2010) Joanna M. Tarr et al.   JOURNAL OF MOLECULAR BIOLOGY

The Identification of Markers of Macrophage Differentiation in PMA-Stimulated THP-1 Cells and Monocyte-Derived Macrophages

(2010) Marc Daigneault et al.   PLoS One

Immunogenic cell death modalities and their impact on cancer treatment

(2009) Oliver Kepp et al.   APOPTOSIS

Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death

(2009) Theocharis Panaretakis et al.   EMBO JOURNAL

C1q Differentially Modulates Phagocytosis and Cytokine Responses during Ingestion of Apoptotic Cells by Human Monocytes, Macrophages, and Dendritic Cells

(2009) D. A. Fraser et al.   JOURNAL OF IMMUNOLOGY

Murine ovarian cancer vascular leukocytes require arginase-1 activity for T cell suppression

(2008) S. Peter Bak et al.   MOLECULAR IMMUNOLOGY