Design and pharmacodynamics of recombinant NZ2114 histidine mutants with improved activity against methicillin-resistant Staphylococcus aureus

The Central Hinge Link Truncation of the Antimicrobial Peptide Fowlicidin-3 Enhances Its Cell Selectivity without Antibacterial Activity Loss

(2016) Pei Qu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

pH-Dependent membrane lysis by using melittin-inspired designed peptides

(2016) A. Kashiwada et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Modification and characterization of a new recombinant marine antimicrobial peptide N2

(2016) Na Yang et al.   PROCESS BIOCHEMISTRY

Antimicrobial Peptides and Peptidomimetics - Potent Therapeutic Allies for Staphylococcal Infections

(2015) Haroon Mohammad et al.   CURRENT PHARMACEUTICAL DESIGN

Antimicrobial Activity of Plectasin NZ2114 in Combination with Cell Wall Targeting Antibiotics Against VanA-TypeEnterococcus faecalis

(2015) Elena B.M. Breidenstein et al.   Microbial Drug Resistance

GAP-initiated constitutive expression of a novel plectasin-derived peptide MP1106 by Pichia pastoris and its activity against Streptococcus suis

(2015) Jian Jiao et al.   PROCESS BIOCHEMISTRY

Killing of Mycobacterium avium by Lactoferricin Peptides: Improved Activity of Arginine- and d-Amino-Acid-Containing Molecules

(2014) Tânia Silva et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Design and recombination expression of a novel plectasin-derived peptide MP1106 and its properties against Staphylococcus aureus

(2014) Xintao Cao et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

High expression of a plectasin-derived peptide NZ2114 in Pichia pastoris and its pharmacodynamics, postantibiotic and synergy against Staphylococcus aureus

(2013) Yong Zhang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Effect of substituting arginine and lysine with alanine on antimicrobial activity and the mechanism of action of a cationic dodecapeptide (CL(14-25)), a partial sequence of cyanate lyase from rice

(2013) Masayuki Taniguchi et al.   BIOPOLYMERS

Synergism between Medihoney and Rifampicin against Methicillin-Resistant Staphylococcus aureus (MRSA)

(2013) Patrick Müller et al.   PLoS One

Design, expression, and characterization of a novel targeted plectasin against methicillin-resistant Staphylococcus aureus

(2012) Ruoyu Mao et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Arginine-rich self-assembling peptides as potent antibacterial gels

(2012) Ana Salomé Veiga et al.   BIOMATERIALS

Meticillin-resistant Staphylococcus aureus (MRSA): global epidemiology and harmonisation of typing methods

(2012) Stefania Stefani et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

In vitro synergy, pharmacodynamics, and postantibiotic effect of 11 antimicrobial agents against Rhodococcus equi

(2012) Steeve Giguère et al.   VETERINARY MICROBIOLOGY

Efficacy of NZ2114, a Novel Plectasin-Derived Cationic Antimicrobial Peptide Antibiotic, in Experimental Endocarditis Due to Methicillin-Resistant Staphylococcus aureus

(2011) Yan Q. Xiong et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Clinical Practice Guidelines by the Infectious Diseases Society of America for the Treatment of Methicillin-Resistant Staphylococcus aureus Infections in Adults and Children

(2011) Catherine Liu et al.   CLINICAL INFECTIOUS DISEASES

Rising incidence of Staphylococcus aureus with reduced susceptibility to vancomycin and susceptibility to antibiotics: a global analysis 2004–2009

(2011) Stephen P. Hawser et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

New insights into meticillin-resistant Staphylococcus aureus (MRSA) pathogenesis, treatment and resistance

(2011) Ian M. Gould et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Characterization of recombinant plectasin: Solubility, antimicrobial activity and factors that affect its activity

(2011) Yalin Yang et al.   PROCESS BIOCHEMISTRY

Cationic Amphiphiles, a New Generation of Antimicrobials Inspired by the Natural Antimicrobial Peptide Scaffold

(2010) B. Findlay et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Contribution of bovine lactoferrin inter-lobe region to iron binding stability and antimicrobial activity against Staphylococcus aureus

(2010) Xuejing Bai et al.   BIOMETALS

Balancing the benefits and costs of antibiotic drugs: the TREAT model

(2010) L. Leibovici et al.   CLINICAL MICROBIOLOGY AND INFECTION

Intracellular activity of the peptide antibiotic NZ2114: studies with Staphylococcus aureus and human THP-1 monocytes, and comparison with daptomycin and vancomycin

(2010) K. S. Brinch et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Plectasin, a Fungal Defensin, Targets the Bacterial Cell Wall Precursor Lipid II

(2010) T. Schneider et al.   SCIENCE

Role of lysine in interaction between surface protein peptides of Streptococcus gordonii and agglutinin peptide

(2010) H. Koba et al.   Oral microbiology and immunology

Geographic Distribution of Staphylococcus aureus Causing Invasive Infections in Europe: A Molecular-Epidemiological Analysis

(2010) Hajo Grundmann et al.   PLOS MEDICINE

In Vivo Pharmacodynamic Characterization of a Novel Plectasin Antibiotic, NZ2114, in a Murine Infection Model

(2009) D. Andes et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

High Cerebrospinal Fluid (CSF) Penetration and Potent Bactericidal Activity in CSF of NZ2114, a Novel Plectasin Variant, during Experimental Pneumococcal Meningitis

(2009) C. Ostergaard et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Expression of antimicrobial peptide LH multimers in Escherichia coli C43(DE3)

(2009) Zi-gang Tian et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The pH sensitivity of histidine-contain- ing lytic peptides

(2009) Zhigang Tu et al.   JOURNAL OF PEPTIDE SCIENCE

Effect of Leucine and Lysine substitution on the antimicrobial activity and evaluation of the mechanism of the HPA3NT3 analog peptide

(2009) Ramamourthy Gopal et al.   JOURNAL OF PEPTIDE SCIENCE

Postantibiotic Effect of Tigecycline against 14 Gram-Positive Organisms

(2008) G. A. Pankuch et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Plectasin has antibacterial activity and no affect on cell viability or IL-8 production

(2008) Shintaro Hara et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Expression and characterization of antimicrobial peptide CecropinAD in the methylotrophic yeast Pichia pastoris

(2008) Feng-liang Jin et al.   PROCESS BIOCHEMISTRY

Predicting cell-penetrating peptides

(2007) Mats Hansen et al.   ADVANCED DRUG DELIVERY REVIEWS