MeCP2, a target of miR-638, facilitates gastric cancer cell proliferation through activation of the MEK1/2–ERK1/2 signaling pathway by upregulating GIT1

MeCP2 Promotes Gastric Cancer Progression Through Regulating FOXF1/Wnt5a/β-Catenin and MYOD1/Caspase-3 Signaling Pathways

(2017) Lingyu Zhao et al.   EBioMedicine

M-COPA, a Golgi Disruptor, Inhibits Cell Surface Expression of MET Protein and Exhibits Antitumor Activity against MET-Addicted Gastric Cancers

(2016) Yoshimi Ohashi et al.   CANCER RESEARCH

The promotion of the transformation of quiescent gastric cancer stem cells by IL-17 and the underlying mechanisms

(2016) Y-X Jiang et al.   ONCOGENE

Methionine Adenosyltransferase 2B–GIT1 Complex Serves as a Scaffold to Regulate Ras/Raf/MEK1/2 Activity in Human Liver and Colon Cancer Cells

(2015) Hui Peng et al.   AMERICAN JOURNAL OF PATHOLOGY

KIAA1324 Suppresses Gastric Cancer Progression by Inhibiting the Oncoprotein GRP78

(2015) J. M. Kang et al.   CANCER RESEARCH

MicroRNA 29 Targets Nuclear Factor-κB–Repressing Factor and Claudin 1 to Increase Intestinal Permeability

(2015) QiQi Zhou et al.   GASTROENTEROLOGY

MiR-138 inhibits cell proliferation and reverses epithelial-mesenchymal transition in non-small cell lung cancer cells by targeting GIT1 and SEMA4C

(2015) Jiefang Li et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Disruption of DNA-methylation-dependent long gene repression in Rett syndrome

(2015) Harrison W. Gabel et al.   NATURE

MECP2 Is a Frequently Amplified Oncogene with a Novel Epigenetic Mechanism That Mimics the Role of Activated RAS in Malignancy

(2015) M. Neupane et al.   Cancer Discovery

miR-638 promotes melanoma metastasis and protects melanoma cells from apoptosis and autophagy

(2015) Animesh Bhattacharya et al.   Oncotarget

MicroRNA-638 inhibits cell proliferation by targeting phospholipase D1 in human gastric carcinoma

(2015) Jiwei Zhang et al.   Protein & Cell

MicroRNA-638 inhibits cell proliferation, invasion and regulates cell cycle by targeting tetraspanin 1 in human colorectal carcinoma

(2015) Jiwei Zhang et al.   Oncotarget

IGF-1R, a target of let-7b, mediates crosstalk between IRS-2/Akt and MAPK pathways to promote proliferation of oral squamous cell carcinoma

(2015) Ling Gao et al.   Oncotarget

miR-638 Suppresses Cell Proliferation in Gastric Cancer by Targeting Sp2

(2014) Ling Yu Zhao et al.   DIGESTIVE DISEASES AND SCIENCES

Increased Helicobacter pylori-associated gastric cancer risk in the Andean region of Colombia is mediated by spermine oxidase

(2014) R Chaturvedi et al.   ONCOGENE

MicroRNA-149 targets GIT1 to suppress integrin signaling and breast cancer metastasis

(2014) S-H Chan et al.   ONCOGENE

MicroRNAs in Cancer

(2013) Gianpiero Di Leva et al.   Annual Review of Pathology-Mechanisms of Disease

miRNA-491-5p and GIT1 Serve as Modulators and Biomarkers for Oral Squamous Cell Carcinoma Invasion and Metastasis

(2013) W.-C. Huang et al.   CANCER RESEARCH

By Hook or by Crook: Multifaceted DNA-Binding Properties of MeCP2

(2013) Jaehoon Shin et al.   CELL

An AT-Hook Domain in MeCP2 Determines the Clinical Course of Rett Syndrome and Related Disorders

(2013) Steven Andrew Baker et al.   CELL

MicroRNA-627 Mediates the Epigenetic Mechanisms of Vitamin D to Suppress Proliferation of Human Colorectal Cancer Cells and Growth of Xenograft Tumors in Mice

(2013) Sathish K.R. Padi et al.   GASTROENTEROLOGY

MAT2B-GIT1 interplay activates MEK1/ERK 1 and 2 to induce growth in human liver and colon cancer

(2013) Hui Peng et al.   HEPATOLOGY

MeCP2 Binds to 5hmC Enriched within Active Genes and Accessible Chromatin in the Nervous System

(2012) Marian Mellén et al.   CELL

Alterations in Cell Proliferation Related Gene Expressions in Gastric Cancer

(2012) Kyungtae Kim et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

Strand-Specific miR-28-5p and miR-28-3p Have Distinct Effects in Colorectal Cancer Cells

(2012) Maria I. Almeida et al.   GASTROENTEROLOGY

The Adaptor Protein and Arf GTPase-activating Protein Cat-1/Git-1 Is Required for Cellular Transformation

(2012) Sungsoo M. Yoo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of GIT1 tyrosine 321 is required for association with FAK at focal adhesions and for PDGF-activated migration of osteoblasts

(2012) Yongxin Ren et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Linking Epigenetics to Human Disease and Rett Syndrome: The Emerging Novel and Challenging Concepts in MeCP2 Research

(2012) Robby Mathew Zachariah et al.   NEURAL PLASTICITY

MeCP2 and Rett syndrome: reversibility and potential avenues for therapy

(2011) Kamal K.E. Gadalla et al.   BIOCHEMICAL JOURNAL

How epigenetics can explain human metastasis: A new role for microRNAs

(2011) Amaia Lujambio et al.   CELL CYCLE

microRNAs as novel epigenetic biomarkers for human cancer

(2011) María Cortés-Sempere et al.   Clinical & Translational Oncology

Adult Neural Function Requires MeCP2

(2011) C. M. McGraw et al.   SCIENCE

CDKL5 is a brain MeCP2 target gene regulated by DNA methylation

(2010) Delphine Carouge et al.   NEUROBIOLOGY OF DISEASE

Variation in Transcription Factor Binding Among Humans

(2010) M. Kasowski et al.   SCIENCE

Recent advances in MeCP2 structure and functionThis paper is one of a selection of papers published in this Special Issue, entitled 29th Annual International Asilomar Chromatin and Chromosomes Conference, and has undergone the Journal’s usual peer review process.

(2009) Kristopher C. Hite et al.   Biochemistry and Cell Biology

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Identification of MYO18A as a Novel Interacting Partner of the PAK2/βPIX/GIT1 Complex and Its Potential Function in Modulating Epithelial Cell Migration

(2009) Rae-Mann Hsu et al.   MOLECULAR BIOLOGY OF THE CELL

GIT1 Mediates VEGF-Induced Podosome Formation in Endothelial Cells

(2008) Jing Wang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

MicroRNA-27a functions as an oncogene in gastric adenocarcinoma by targeting prohibitin

(2008) Tao Liu et al.   CANCER LETTERS

Structures of Dimeric GIT1 and Trimeric β-PIX and Implications for GIT–PIX Complex Assembly

(2008) Oliver Schlenker et al.   JOURNAL OF MOLECULAR BIOLOGY

MeCP2, a Key Contributor to Neurological Disease, Activates and Represses Transcription

(2008) M. Chahrour et al.   SCIENCE