Cholesterol-Containing Nuclease-Resistant siRNA Accumulates in Tumors in a Carrier-free Mode and Silences MDR1 Gene

Published 2017 View Full Article

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Title
Cholesterol-Containing Nuclease-Resistant siRNA Accumulates in Tumors in a Carrier-free Mode and Silences MDR1 Gene
Authors
Keywords
cholesterol-containing siRNA, MDR1, 2’-O-methyl modification, tumor xenograft in SCID mice, multiple drug resistance, biodistribution of siRNA
Journal
Molecular Therapy-Nucleic Acids
Volume 6, Issue -, Pages 209-220
Publisher
Elsevier BV
Online
2017-01-06
DOI
10.1016/j.omtn.2016.12.011

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