Article
Ecology
Scott Lockwood, Chris Greening, Federico Baltar, Sergio E. Morales
Summary: Marine microbial communities rely on dissolved organic phosphorus (DOP) remineralisation to meet phosphorus (P) requirements. This study extensively surveyed the genomic and metagenomic distribution of phosphonate metabolism pathways in marine bacteria and archaea, revealing the prevalence of substrate-specific catabolism and the less widespread broad-specificity catabolism. The study also found that phosphonate cycling genes were abundant in marine metagenomes, especially in the mesopelagic zone and during winter sampling.
Article
Food Science & Technology
Ilaria Piccialli, Valentina Tedeschi, Francesca Boscia, Roselia Ciccone, Antonella Casamassa, Valeria de Rosa, Paolo Grieco, Agnese Secondo, Anna Pannaccione
Summary: The marine toxin BDS-I was found to improve [Ca2+](i) transients in rat primary cortical astrocytes exposed to A beta(1-42) oligomers by affecting K(V)3.4 channels, thereby preventing A beta(1-42)-induced ER stress and cell suffering.
Article
Environmental Sciences
Enrique Lozano-Bilbao, Jose Maria Espinosa, Thabatha Thorne-Bazarra, Arturo Hardisson, Soraya Paz, Dailos Gonzalez-Weller, Carmen Rubio, Angel J. Gutierrez
Summary: The objective of this study was to investigate the variations in concentrations of heavy metals and trace elements in the sea anemone Anemonia sulcata, and to determine their relationship with different sources of contamination. The results showed that the concentrations of metals and trace elements were significantly higher in the polluted areas compared to the control area, with the anemones from the harbour showing the highest number and concentration of metals.
MARINE POLLUTION BULLETIN
(2023)
Article
Chemistry, Medicinal
Dongchen An, Ernesto Lopes Pinheiro-Junior, Laszlo Beress, Irina Gladkikh, Elena Leychenko, Eivind A. B. Undheim, Steve Peigneur, Jan Tytgat
Summary: AsKC11, a Kunitz peptide found in the venom of A. sulcata, is the first peptide shown to directly activate neuronal GIRK1/2 channels independent from Gi/o protein activity, without affecting the inward-rectifier potassium channel (IRK1) and with only a minor effect on K(V)1.6 channels. Thus, AsKC11 is a novel activator of GIRK channels resulting in larger K+ currents because of an increased chord conductance.
Article
Biochemistry & Molecular Biology
Ana Maria Melendez-Perez, Almudena Escobar Nino, Rafael Carrasco-Reinado, Laura Martin Diaz, Francisco Javier Fernandez-Acero
Summary: Marine ecosystems are rich in biodiversity and remain largely unknown. Molecular biology analyses have been conducted to understand the biological processes in this ecosystem, providing biotechnological solutions for diseases and developing new tools for biomedicine and agri-food. Proteomics approaches have revealed the potential use of proteins for diagnostic tools and the identification of bioactive compounds.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Mercedes Pena, Cristina Mesas, Gloria Perazzoli, Rosario Martinez, Jesus M. Porres, Kevin Doello, Jose Prados, Consolacion Melguizo, Laura Cabeza
Summary: Anemonia sulcata has potential as a source of marine natural products with antioxidant and antitumor activity. A bioguided chromatographic fractionation assay revealed that the 20% and 40% fractions had antioxidant and antiproliferative activities in colon cancer cells, respectively. Further characterization and isolation of the bioactive compounds are required.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Environmental Sciences
Maria del Carmen Gomez-Regalado, Julia Martin, Felix Hidalgo, Juan Luis Santos, Irene Aparicio, Esteban Alonso, Alberto Zafra-Gomez
Summary: The bioconcentration kinetics of atenolol and carbamazepine in marine organisms were assessed under controlled laboratory conditions. Carbamazepine showed higher uptake and excretion rates, resulting in a higher bioconcentration factor (BCF), while both were below the limits set by the European Union. The measured BCF using kinetic data showed differences compared to those predicted using steady-state concentrations, possibly due to the steady state not being reached. Specific to the organisms, atenolol exhibited different bioconcentration patterns in different species, with Holothuria tubulosa having the highest BCF. The study also highlighted tissue differences within Holothuria tubulosa. This work is the first to model the bioconcentration of atenolol and carbamazepine in holothurians and anemones.
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
(2023)
Article
Chemistry, Physical
Saurav Das, Priyam Das, Payel Dowari, Basab Kanti Das, Debapratim Das
Summary: This article presents a transient assembly of a vesicular nanozyme mediated by a chemoenzymatic pH clock, which achieves efficient hydrolase-peroxidase tandem catalysis through distinct confinement effects. The assembly is controlled by a pH clock composed of alkaline TRIS buffer and glucose oxidase (GOx) catalyzed oxidation of glucose.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Biology
Laura Cabeza, Mercedes Pena, Rosario Martinez, Cristina Mesas, Milagros Galisteo, Gloria Perazzoli, Jose Prados, Jesus M. Porres, Consolacion Melguizo
Summary: Research on the invertebrate Anemonia sulcata has shown that its extracts exhibit significant antioxidant and antitumor activity against colorectal cancer, potentially serving as a source of bioactive compounds for future therapy and prevention. The extracts are rich in polyunsaturated fatty acids, and the absence of symbiont may enhance their antitumor properties. Further studies are needed to uncover the bioactive compounds and mechanisms of action in Anemonia sulcata.
Article
Agriculture, Dairy & Animal Science
Han Li, Yifeng Zhang, Rong Li, Yan Wu, Dingran Zhang, Hongrun Xu, Yangdong Zhang, Zhili Qi
Summary: This study found that climatic conditions under different temperature-humidity index levels may induce varying degrees of oxidative stress, inflammation response, and stress hormone imbalances in lactating dairy cows.
Article
Multidisciplinary Sciences
Jose O. Valdebenito, Naerhulan Halimubieke, Adam Z. Lendvai, Jordi Figuerola, Gotz Eichhorn, Tamas Szekely
Summary: The study found that immune system in birds exhibit both sex differences and seasonal variations, with males showing higher immune responses and abilities during the breeding season. The study also revealed that sex differences in immune status are more pronounced during the breeding period compared to the non-breeding period.
SCIENTIFIC REPORTS
(2021)
Article
Chemistry, Applied
Michele Woelk, Sanja Milkovska-Stamenova, Theres Schroeter, Ralf Hoffmann
Summary: Climate and feeding impact the composition of bovine milk, which is further altered by thermal treatment inducing oxidation and Maillard reactions. This study found similarities in protein modifications between regular and hay milk, as well as comparable effects of pasteurization and UHT treatment on both milk types. In particular, UHT treatment led to increased identification of modifications and relative quantities of lactosylated peptides.
Article
Thermodynamics
Xin Zhao, Wenyu Zheng, Zhihua Hou, Heng Chen, Gang Xu, Wenyi Liu, Honggang Chen
Summary: A modeling framework of a multi-energy system is established in this research, proposing a new operation strategy and selecting the most suitable hybrid operation strategy through comparative analysis. The study results indicate that the hybrid operation strategy has advantages in saving operation cost, reducing carbon dioxide emission, and primary energy consumption.
Article
Ecology
Vitor Carvalho-Rocha, Carlos A. Peres, Selvino Neckel-Oliveira
Summary: In this study, the researchers investigated the spatiotemporal diversity patterns of frogs along a subtropical elevational gradient and assessed the importance of temperature in explaining these patterns. The results showed that temperature was the main factor determining the observed spatial and spatiotemporal variation. Moreover, the authors suggested that other factors, such as species characteristics, may also regulate frog activity patterns throughout the year along the elevational gradient.
JOURNAL OF BIOGEOGRAPHY
(2023)
Article
Environmental Sciences
Rongxiang Wang, Jie Min, Yuechen Li, Yunyun Hu, Shiqi Yang
Summary: Rapid urbanization has led to the deterioration of the thermal environment in urban areas, impacting the sustainable development of cities and the health of residents. This study conducted quantitative and qualitative analyses of the interannual and seasonal variation of the thermal environment in Chongqing. The study also explored the mechanism by which various human and natural factors affect the urban thermal environment in different seasons.
Article
Physiology
Maria Giovanna Parisi, Jessica Pirrera, Claudia La Corte, Mariano Dara, Daniela Parrinello, Matteo Cammarata
Summary: Filter-feeding organisms can accumulate xenobiotics and other substances in their tissues, making them useful as sentinel organisms in marine biomonitoring. The cellular immunity of bivalves can be affected by chemical contaminants, such as methylmercury, resulting in altered hemocyte morphology and function. The Mediterranean mussel, Mytilus galloprovincialis, showed changes in phagocytosis, lysosomal membrane, cytotoxic molecule release, morphology, and cytoskeleton when exposed to sub-lethal concentrations of methylmercury, highlighting their sensitivity to environmental pollutants.
JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMS AND ENVIRONMENTAL PHYSIOLOGY
(2021)
Article
Environmental Sciences
M. G. Parisi, A. Giacoletti, C. Mandaglio, M. Cammarata, G. Sara
Summary: Anthropogenic pressure interacts with climate change effects and other stressors on marine biota, causing negative impacts on biodiversity and ecosystem functioning. Impairment of individual functional traits can lead to ecological consequences, and a multiscale approach is necessary to monitor the effects of anthropogenic disturbance on ecosystem functioning.
MARINE ENVIRONMENTAL RESEARCH
(2021)
Article
Fisheries
Emanuele Conforto, Luciano Vilchez-Gomez, Daniela Parrinello, Maria Giovanna Parisi, Maria Angeles Esteban, Matteo Cammarata, Francisco A. Guardiola
Summary: The study focused on characterizing immune defense parameters in the skin mucus of European eels following bacterial challenges. Results showed increased peroxidase and lysozyme activity in the skin mucus of eels challenged with Vibrio anguillarum, while antiprotease activity increased at 24 hours but was undetected at 48 and 72 hours post-challenge. Conversely, protease activity decreased at 48 and 72 hours post-challenge.
FISH & SHELLFISH IMMUNOLOGY
(2021)
Editorial Material
Biology
Loriano Ballarin, Matteo Cammarata, Pierangelo Luporini
Article
Biochemistry & Molecular Biology
Maria Giovanna Parisi, Annalisa Grimaldi, Nicolo Baranzini, Claudia La Corte, Mariano Dara, Daniela Parrinello, Matteo Cammarata
Summary: Cnidaria are excellent models for studying regenerative processes due to their anatomical simplicity and ability to regenerate missing body parts, particularly highlighting the importance of mesoglea in the process, acting as a scaffold for tissue regeneration.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Environmental Sciences
Angela Cuttitta, Bernardo Patti, Marianna Musco, Tiziana Masullo, Francesco Placenti, Enza Maria Quinci, Francesca Falco, Carmelo Daniele Bennici, Marilena Di Natale, Vito Pipitone, Matteo Cammarata, Isabel Maneiro, Stefania Russo, Marco Torri
Summary: The European anchovy is an important fishing resource in the Sicilian Channel, with two spawning areas and different larval subpopulations. Morphological and growth differences, as well as biochemical composition differences, suggest variations in parental reproduction efforts and nutritional conditions between the two spawning regions.
Article
Fisheries
M. G. Parisi, N. Baranzini, M. Dara, C. La Corte, J. Vizioli, M. Cammarata
Summary: This study evaluated the immunological parameters of Mediterranean mussels in response to Vibrio splendidus infection. The results showed that TLR4 was activated before bacterial infection and recruited the MyD88 adapter. Challenging with Gram-negative bacteria caused a massive migration of AIF-1(+) hemocytes, and the ribonuclease RNASET2 may play a key role in this recruitment. This research contributes to a better understanding of the complex molecular defense mechanisms in bivalve molluscs and can guide the development of immunological response assessment methods in aquaculture.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Editorial Material
Biochemistry & Molecular Biology
Claudia La Corte, Nicolo Baranzini, Annalisa Grimaldi, Maria Giovanna Parisi
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Environmental Sciences
M. Dara, M. G. Parisi, C. La Corte, G. Benenati, D. Parrinello, D. Piazzese, M. Cammarata
Summary: We report the mucus bacterial agglutination response of Sabella spallanzanii after exposure to inorganic arsenic (As). High concentrations of As inhibit pathogen recognition, but the response to As concentrations remains similar across seasons. This suggests that Sabella spallanzanii may adapt to high As concentrations and it is related to predation defense.
MARINE POLLUTION BULLETIN
(2022)
Article
Biochemistry & Molecular Biology
Claudia La Corte, Mariano Dara, Federica Bertini, Daniela Parrinello, Daniela Piazzese, Maria Giovanna Parisi
Summary: This study aimed to investigate the immune responses of the polychaete Sabella spallanzanii after exposure to copper sulphate and Escherichia coli infection, in order to validate its use as a model organism in marine-coastal biomonitoring programmes. The results demonstrate the immunomodulating effect of copper sulphate on S. spallanzanii, which is associated with oxidative stress and inflammatory markers.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Claudia La Corte, Nicolo Baranzini, Mariano Dara, Camilla Bon, Annalisa Grimaldi, Maria Giovanna Parisi, Maria Grazia Zizzo, Matteo Cammarata
Summary: This study investigates the differences and characteristics in injured and healthy tissues of the soft coral Anemonia viridis through histological investigation. In addition, positron emission tomography is used for the first time in invertebrates to study regeneration over a longer time period. The results indicate that Mediterranean anthozoan is a valuable model for studying regeneration and many events observed are highly conserved across different phyla.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Fisheries
Mariano Dara, Maria Dioguardi, Mirella Vazzana, Irene Vazzana, Pierluigi Carbonara, Sebastien Alfonso, Matteo Cammarata
Summary: This study investigated the role of spatial exploration and territoriality in gilthead seabream, and found that time is important in forming social organization while territoriality is related to immune response.
Article
Fisheries
Mariano Dara, Maria Dioguardi, Mirella Vazzana, Irene Vazzana, Davide Accardi, Pierluigi Carbonara, Sebastien Alfonso, Matteo Cammarata
Summary: This paper investigates the effects of social stress on gilt-head bream and finds that social stress can affect the physiological state and immune response of fish. The study provides insights into the relationship between behavior and physiology in fish.
