Review
Urology & Nephrology
Xiaohu Zhao, Yuanli Wang, Chaozhao Liang
Summary: This meta-analysis confirms a positive non-linear dose-response relationship between smoking intensity, pack-years of smoking, smoking duration (years) and the risk of bladder cancer. However, the risk reaches a plateau only when smoking intensity reaches 20 cigarettes/day.
INTERNATIONAL UROLOGY AND NEPHROLOGY
(2022)
Review
Nutrition & Dietetics
Huilei Zhao, Kaibo Mei, Lun Yang, Xiao Liu, Lixia Xie
Summary: Results from 14 studies involving over 493,000 participants indicated that there was no clear association between green tea consumption and esophageal cancer risk with each additional cup of green tea. However, a potential protective effect of green tea was observed in women. Further large-scale studies are needed to confirm these findings and explore potential biases.
Review
Oncology
Yongfeng Lao, Xiaolong Li, Lijuan He, Xin Guan, Rongxin Li, Yanan Wang, Yanyou Li, Yunchang Wang, Xu Li, Shuai Liu, Zhilong Dong
Summary: The study found no significant association between alcohol consumption and bladder cancer risk in the entire population, but there was a linear dose-response relation in those who consume alcohol from liquor or spirits. Additionally, alcohol may elevate the risk of bladder cancer in males in a dose-independent way.
FRONTIERS IN ONCOLOGY
(2021)
Article
Nutrition & Dietetics
Fang Zheng, Kelie Chen, Jiamin Zhong, Song Tang, Sinan Xu, Weiguo Lu, Yihua Wu, Dajing Xia
Summary: Numerous studies have indicated that tea consumption may inhibit the development of gynecologic tumors; however, the association between tea intake and gynecologic cancers remains controversial. This study reviewed 19 cohort studies and found no significant association between tea intake and gynecologic tumor risk. Subgroup analyses suggested a preventive effect of non-herbal tea, particularly black tea, on ovarian cancer. Although not statistically significant, there was a decreasing trend in ovarian cancer risk with tea consumption of 1.40 to 3.12 cups per day. Further research is needed to validate the potential weak preventive effect of green tea on gynecologic cancers.
Review
Biochemistry & Molecular Biology
Lijun Yuan, Huifang Hu, Tianze Li, Jinli Zhang, Yifei Feng, Xingjin Yang, Yang Li, Yuying Wu, Xi Li, Hao Huang, Fulan Hu, Chuanqi Chen, Ming Zhang, Yang Zhao, Dongsheng Hu
Summary: This meta-analysis based on prospective cohort studies found a positive association between ultra-processed food (UPF) consumption and the risk of cardiovascular events (CVEs) and all-cause mortality. Each additional daily serving of UPF was associated with a 4% increased risk for CVEs and a 2% increased risk for all-cause mortality. The risk of CVEs showed a linear upward trend with increasing UPF intake, while the risk of all-cause mortality showed a nonlinear upward trend. These findings suggest the importance of controlling UPF intake in daily diet.
Review
Biochemistry & Molecular Biology
Chang Ma, Xuehui Zheng, Yi Yang, Peili Bu
Summary: This study clarified the effects of black tea supplementation on blood pressure through a systematic review and meta-analysis, suggesting a favorable impact on cardiovascular health. No significant influence of dose or duration of black tea flavonoid supplementation was found. Sensitivity analysis showed no individual study had a significant impact on the results.
Review
Cardiac & Cardiovascular Systems
Heng-Zhi Zhang, Bo Shao, Qi-Yu Wang, Yi-Han Wang, Ze-Zhong Cao, Lu-Lu Chen, Jin-Yu Sun, Mu-Feng Gu
Summary: This study aimed to investigate the dose-response association between alcohol consumption and atrial fibrillation (AF) risk. The findings showed that moderate alcohol intake significantly increased the risk of AF in males but not in females. The cubic spline regression analysis indicated a significant positive association between daily alcohol intake and AF risk. Therefore, alcohol consumption should be restricted to reduce the risk of AF.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Review
Oncology
Liqi Zhang, Junyan Ma, Kaiqing Lin, Yifei Lv, Huihua Wang, Jun Lin
Summary: A meta-analysis on the relationship between tea consumption and endometrial cancer risk found no significant association between the two. While significant heterogeneity was detected among the studies, no publication bias was found. Further research and cohort studies are recommended to confirm these results.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
(2021)
Article
Nutrition & Dietetics
Yali Wang, Peng Du, Qi Xiao, Jianfeng Li, Xiao Liu, Jinfeng Tan, Xingjian Zhang
Summary: This study found that patients with high serum albumin levels had a lower risk of atrial fibrillation compared to those with low albumin levels, and for every 10 g/L increase in serum albumin level, the risk of atrial fibrillation decreased by 36%.
FRONTIERS IN NUTRITION
(2021)
Review
Nutrition & Dietetics
Ying Zhu, Chun-Xiang Hu, Xu Liu, Rui-Xia Zhu, Ben-Qiao Wang
Summary: This meta-analysis confirms that coffee and tea consumption is associated with a reduced risk of cognitive disorders, with 2.5 cups of coffee per day minimizing the risk of AD and 1 cup of tea per day leading to an 11% reduction in cognitive deficits.
Article
Medicine, General & Internal
Qing Su, Xiaohui Sun, Liwen Zhu, Qin Yan, Peiwen Zheng, Yingying Mao, Ding Ye
Summary: This study found that breastfeeding has a significant protective effect on reducing the risk of childhood leukemia, with evidence suggesting a non-linear dose-response relationship. Further research is needed to confirm the association between breastfeeding and the risk of childhood neuroblastoma.
Review
Cardiac & Cardiovascular Systems
Yalin Cao, Xiao Liu, Zhengbiao Xue, Kang Yin, Jianyong Ma, Wengen Zhu, Fuwei Liu, Jun Luo, Junyi Sun
Summary: This meta-analysis suggests that coffee consumption is associated with a trend towards reducing the risk of atrial fibrillation in a dose-response manner, although the results were not statistically significant. An increase in daily coffee consumption of one cup was associated with a 2% reduced risk of atrial fibrillation.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Psychiatry
L. S. Ran, W. H. Liu, Y. Y. Fang, S. B. Xu, J. Li, X. Luo, D. J. Pan, M. H. Wang, W. Wang
Summary: The study found that low alcohol and coffee consumption can reduce the risk of cognitive deficits, while green tea consumption is a significant protective factor for cognitive health.
EPIDEMIOLOGY AND PSYCHIATRIC SCIENCES
(2021)
Review
Nutrition & Dietetics
Farzaneh Asoudeh, Fatemeh Dashti, Ahmad Jayedi, Amirhossein Hemmati, Abdulmannan Fadel, Hamed Mohammadi
Summary: This meta-analysis examined the association between dietary caffeine, different types of coffee and tea consumption, and the risk of rheumatoid arthritis (RA). The results showed that higher intake of coffee and decaffeinated coffee was associated with an increased risk of RA, while there was no significant association between caffeinated coffee, tea, or caffeine intake and RA risk.
FRONTIERS IN NUTRITION
(2022)
Article
Geriatrics & Gerontology
S-L Xia, Z-Y Ma, B. Wang, S-Y Guo, X-X Zhou, Feng Gao
Summary: Increased tea consumption may provide a protective role in the risk of fracture, especially in the categories of high and mild tea consumption. Further exploration of the benefits of tea consumption should be based on individual characteristics.
JOURNAL OF NUTRITION HEALTH & AGING
(2021)
Editorial Material
Immunology
Yejinpeng Wang, Lingao Ju, Zicheng Guo, Kaiyu Qian, Hongbo Chen, Yi Zhang, Yu Xiao, Xinghuan Wang
CELLULAR & MOLECULAR IMMUNOLOGY
(2021)
Letter
Virology
Yufeng Shang, Tao Liu, Jingfeng Li, Xinghuan Wang, Fuling Zhou
JOURNAL OF MEDICAL VIROLOGY
(2021)
Review
Chemistry, Medicinal
Cheng Fang, Lan Wu, Cong Zhu, Wen-Zhong Xie, Hailiang Hu, Xian-Tao Zeng
Summary: Human microbiome research has shown the critical role of oral microbiome in health and disease, with dysbiosis being a contributory cause for diseases in multiple body systems, including a possible link between periodontal disease and prostatic disease. Research is progressing towards oral microbiome-based diagnosis and therapy for potential drug targets in systemic diseases.
MEDICINAL RESEARCH REVIEWS
(2021)
Article
Cell Biology
Hong Weng, Shuai Yuan, Qiao Huang, Xian-Tao Zeng, Xing-Huan Wang
Summary: This study utilized multi-omics data analysis to uncover the molecular basis of different immune phenotypes in bladder cancer, revealing distinct subclusters associated with PD-L1 and IFNG expression, as well as features related to DNA mutations and differentially expressed genes.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
(2021)
Article
Endocrinology & Metabolism
Li-Sha Luo, Jun-Feng Jiang, Hang-Hang Luan, Hao Zi, Cong Zhu, Bing-Hui Li, Xian-Tao Zeng
Summary: The incidence and prevalence of prostate cancer increased in almost all countries in Asia, with mortality and DALY also increasing in over half of the countries. Significant regional disparities were found, with hot spots located in Western Asia for incidence, prevalence, mortality, and DALY. Additionally, Socio-Demographic Index had a positive association with mortality and negative association with DALY and MIR.
Article
Medicine, General & Internal
Xuhui Li, Hua Fan, Hao Zi, Hankun Hu, Binghui Li, Jiao Huang, Pengcheng Luo, Xiantao Zeng
Summary: This study aimed to estimate the global and regional burden of bacterial antimicrobial resistance (AMR) in urinary tract infections (UTI) in 2019. The results showed that globally, there were approximately 64.89 thousand deaths attributed to and 0.26 million deaths associated with bacterial AMR in UTI. Escherichia coli and Klebsiella pneumoniae had the highest resistance rates, including resistance to fluoroquinolones, carbapenems, and third-generation cephalosporins. Tailored strategies, such as enhanced surveillance and rational use of antibiotics, should be developed for different regions based on their specific pathogen-antibiotic situations and resources.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Computer Science, Artificial Intelligence
Yaqian Liang, Fazhi He, Xiantao Zeng, Baosheng Yu
Summary: In this paper, a new convolutional neural network method for 3D mesh recognition is proposed, which introduces an effective feature-preserved mesh pooling mechanism. Experimental results demonstrate that the proposed method outperforms previous methods in terms of classification/segmentation accuracy and feature preservation performance.
APPLIED SOFT COMPUTING
(2022)
Article
Medicine, General & Internal
Bing Zhao, Kaiyan Hu, Xiantao Zeng, J. S. W. Kwong, Bo Li, Hao Chen, Guoxiang Tian, Jun Xiong, Zhaoxia Li, Junqiang Niu, Mingyue Jiao, Jinwei Yang, Fengxing Ding, Chen Liu, Liang Du, Junhua Zhang, Bin Ma
Summary: The PRISMA-ATCM reporting guidelines were developed to address the deficiencies in the quality of SRs/MAs of animal experiments in the field of TCM. Through analysis of published SRs/MAs and consultation with experts, the guidelines were extensively revised and expanded to specifically include details about TCM intervention and animal characteristics, with illustrative examples and explanations provided for each item. PRISMA-ATCM has the potential to significantly improve the quality of SRs/MAs in the field of TCM.
JOURNAL OF EVIDENCE BASED MEDICINE
(2022)
Article
Medicine, Research & Experimental
Yong-Bo Wang, Lan Yang, Yu-Qing Deng, Si-Yu Yan, Li-Sha Luo, Ping Chen, Xian-Tao Zeng
Summary: This study found independent causal relationships between high waist circumference, BMI, and sedentary behavior with BPH using Mendelian randomization study design.
JOURNAL OF TRANSLATIONAL MEDICINE
(2022)
Article
Oncology
Yu Xiao, Xiaodong Wang, Hong Weng, Zhao Ding, Kaiyu Qian, Wan Jin, Sen Lu, Lingao Ju, Zhiwen He, Gang Wang, Xiaoyu Xie, Dongmei Liu, Zhou Fan, Kai Wu, Sheng Li, Huanhuan Guo, Guofeng Qian, Wei Jiang, Yunji Leng, Junpeng Zhao, Xinyue Cao, Minsheng Peng, Congqing Jiang, Li Li, Yi Zhang, Xinghuan Wang
CLINICAL AND TRANSLATIONAL MEDICINE
(2022)
Article
Cell Biology
Shuai Yuan, Shao-Hua He, Lu-Yao Li, Shu Xi, Hong Weng, Jin-Hui Zhang, Dan-Qi Wang, Meng-Meng Guo, Haozhe Zhang, Shuang-Ying Wang, Dao-Jing Ming, Meng-Yang Liu, Hailiang Hu, Xian-Tao Zeng
Summary: SLC12A5 functions as an oncogene to promote tumor progression and castration resistance of prostate cancer through the N6-methyladenosine (m(6)A) reader YTHDC1 and the transcription factor HOXB13. The enhanced expression of SLC12A5 mRNA is associated with neuroendocrine prostate cancer (NEPC) progression and poor survival. SLC12A5 promotes castration resistance, cell proliferation, and migration of prostate cancer by forming a complex with nuclear m(6)A reader YTHDC1 to upregulate HOXB13.
CELL DEATH & DISEASE
(2023)
Review
Nursing
Zhi Cheng, Shanzhen Yu, Wen Zhang, Xinxin Liu, Yijin Shen, Hong Weng
Summary: The use of virtual reality technology can significantly improve pain, anxiety, and fear symptoms of pediatric cancer patients, helping to improve the patients' psychological state.
ASIA-PACIFIC JOURNAL OF ONCOLOGY NURSING
(2022)
Article
Computer Science, Information Systems
Shixiao Wu, Xinghuan Wang, Chengcheng Guo
Summary: During feature propagation, the low-level convolution layers in the forward feature propagation network lack semantic information, leading to information loss when transferring fine-grained information to higher-level convolution layers. To address this, a multi-stage feature fusion network is introduced to handle the interaction between low-level and high-level convolution layers. By incorporating a two-way feature feedback network and feature fusion mechanism, a new object detection network called Feature Pyramid Network (FPN)-based Feature Fusion Single Shot Multibox Detector (FFSSD) is developed. The proposed network achieves a mAP of 83.58% for prostate capsule image detection, demonstrating real-time detection capability. The context interaction mechanism effectively transfers high-level semantic information to low-level convolution layers, resulting in convolution with richer location and semantic information.
Article
Medicine, General & Internal
Hong Weng, Kang-Ping Xiong, Wang Wang, Kai-Yu Qian, Shuai Yuan, Gang Wang, Fang Yu, Jun Luo, Meng-Xin Lu, Zhong-Hua Yang, Tao Liu, Xing Huang, Hang Zheng, Xing-Huan Wang
Summary: The study identified aspartoacylase (ASPA) as a novel inhibitor of prostate cancer (PCa) progression. ASPA was down-regulated in PCa tissue samples and its decreased expression was associated with patients' prognosis. ASPA was found to interact with and inhibit the phosphorylation of the LYN protein and its downstream targets, playing an important role in PCa development. These findings provide new insights into the tumor-suppressive function of ASPA in PCa and suggest its potential as a prognostic biomarker and therapeutic target.
MILITARY MEDICAL RESEARCH
(2023)
Article
Medicine, General & Internal
Lu-Yao Li, Jie Han, Lan Wu, Cheng Fang, Wei-Guang Li, Jia-Min Gu, Tong Deng, Chang-Jiang Qin, Jia-Yan Nie, Xian-Tao Zeng
Summary: The study investigates the regulation of benign prostatic hyperplasia (BPH) on gut microbiota composition and metabonomics. The results show an association between gut microbiota and BPH, but the causal relationship between the two is unclear. Further studies are needed to elucidate the potential mechanisms and causal relationships between BPH and gut microbiota.
MILITARY MEDICAL RESEARCH
(2022)
