Novel GLP-1 Analog Supaglutide Reduces HFD-Induced Obesity Associated with Increased Ucp-1 in White Adipose Tissue in Mice

A novel glucagon-like peptide 1/glucagon receptor dual agonist improves steatohepatitis and liver regeneration in mice

(2017) M. Pilar Valdecantos et al.   HEPATOLOGY

Cardiovascular Benefits of Native GLP-1 and its Metabolites: An Indicator for GLP-1-Therapy Strategies

(2017) Junfeng Li et al.   Frontiers in Physiology

Role of glucagon-like peptide 1 receptor agonists in management of obesity

(2016) D. Isaacs et al.   AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY

GLP-1 analogue improves hepatic lipid accumulation by inducing autophagy via AMPK/mTOR pathway

(2016) Qin He et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Antiobesity efficacy of GLP-1 receptor agonist liraglutide is associated with peripheral tissue-specific modulation of lipid metabolic regulators

(2016) Juan Decara et al.   BIOFACTORS

GLP-1 as a target for therapeutic intervention

(2016) Surya Panicker Rajeev et al.   CURRENT OPINION IN PHARMACOLOGY

GLP-1 receptor agonist promotes brown remodelling in mouse white adipose tissue through SIRT1

(2016) Fen Xu et al.   DIABETOLOGIA

Browning of White Fat: Novel Insight Into Factors, Mechanisms, and Therapeutics

(2016) Nevena Jeremic et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Glucagon-like peptide 1 decreases lipotoxicity in non-alcoholic steatohepatitis

(2016) Matthew J. Armstrong et al.   JOURNAL OF HEPATOLOGY

Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 study

(2016) Matthew James Armstrong et al.   LANCET

Twenty-four-week effects of liraglutide on body composition, adherence to appetite, and lipid profile in overweight and obese patients with type 2 diabetes mellitus

(2016) Simone Perna et al.   Patient Preference and Adherence

Pathogenesis of Nonalcoholic Steatohepatitis: Interactions between Liver Parenchymal and Nonparenchymal Cells

(2016) Nancy Magee et al.   Biomed Research International

Dulaglutide

(2015) Angela M. Thompson et al.   ANNALS OF PHARMACOTHERAPY

Glucagon-Like Peptide-1 Formulation - the Present and Future Development in Diabetes Treatment

(2015) Chooi Yeng Lee   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Emerging New Therapies for the Treatment of Type 2 Diabetes Mellitus: Glucagon-like Peptide-1 Receptor Agonists

(2015) Christopher A. Lindamood et al.   CLINICAL THERAPEUTICS

Central GLP-1 receptor signalling accelerates plasma clearance of triacylglycerol and glucose by activating brown adipose tissue in mice

(2015) Sander Kooijman et al.   DIABETOLOGIA

Contribution of brown adipose tissue activity to the control of energy balance by GLP-1 receptor signalling in mice

(2015) Kristy M. Heppner et al.   DIABETOLOGIA

A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management

(2015) Xavier Pi-Sunyer et al.   NEW ENGLAND JOURNAL OF MEDICINE

The effect of neuropeptide Y on brown-like adipocyte's differentiation and activation

(2015) Yun Wan et al.   PEPTIDES

Formation and activation of thermogenic fat

(2015) Jun Wu et al.   TRENDS IN GENETICS

Liraglutide and obesity: a review of the data so far

(2015) Ellen Ladenheim   Drug Design Development and Therapy

Brown and white adipose tissues: intrinsic differences in gene expression and response to cold exposure in mice

(2014) Meritxell Rosell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Toll-like receptor-4 signalling in the progression of non-alcoholic fatty liver disease induced by high-fat and high-fructose diet in mice

(2014) Jing Liu et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

GLP-1 Agonism Stimulates Brown Adipose Tissue Thermogenesis and Browning Through Hypothalamic AMPK

(2014) D. Beiroa et al.   DIABETES

Effects of GLP-1 on appetite and weight

(2014) Meera Shah et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Once-weekly albiglutide in the management of type 2 diabetes: patient considerations

(2014) Sarah Anderson et al.   Patient Preference and Adherence

Adiposity and Insulin Resistance in Humans: The Role of the Different Tissue and Cellular Lipid Depots

(2013) Samantha Hocking et al.   ENDOCRINE REVIEWS

The novel dipeptidyl peptidase-4 inhibitor teneligliptin prevents high-fat diet-induced obesity accompanied with increased energy expenditure in mice

(2013) Sayaka Fukuda-Tsuru et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

(2012) Jun Wu et al.   CELL

Direct Control of Brown Adipose Tissue Thermogenesis by Central Nervous System Glucagon-Like Peptide-1 Receptor Signaling

(2012) S. H. Lockie et al.   DIABETES

Brown adipose tissue regulates glucose homeostasis and insulin sensitivity

(2012) Kristin I. Stanford et al.   JOURNAL OF CLINICAL INVESTIGATION

Relative shrinkage of adipocytes by paraffin in proportion to plastic embedding in human adipose tissue before and after weight loss

(2012) Sanne P.M. Verhoef et al.   Obesity Research & Clinical Practice

Peripheral and Central GLP-1 Receptor Populations Mediate the Anorectic Effects of Peripherally Administered GLP-1 Receptor Agonists, Liraglutide and Exendin-4

(2011) Scott E. Kanoski et al.   ENDOCRINOLOGY

The Safety of Incretin-Based Therapies—Review of the Scientific Evidence

(2011) Daniel J. Drucker et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Toward a More Complete (and Less Controversial) Understanding of Energy Expenditure and Its Role in Obesity Pathogenesis

(2010) K. J. Kaiyala et al.   DIABETES

A Recurring Problem With the Analysis of Energy Expenditure in Genetic Models Expressing Lean and Obese Phenotypes

(2010) A. A. Butler et al.   DIABETES

Liraglutide

(2010) Daniel J. Drucker et al.   NATURE REVIEWS DRUG DISCOVERY

Novel GLP-1 Fusion Chimera as Potent Long Acting GLP-1 Receptor Agonist

(2010) Qinghua Wang et al.   PLoS One

Chronic Peroxisome Proliferator-activated Receptor γ (PPARγ) Activation of Epididymally Derived White Adipocyte Cultures Reveals a Population of Thermogenically Competent, UCP1-containing Adipocytes Molecularly Distinct from Classic Brown Adipocytes

(2009) Natasa Petrovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Saturated fatty acid-induced insulin resistance is associated with mitochondrial dysfunction in skeletal muscle cells

(2009) Sandro M. Hirabara et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study

(2009) Arne Astrup et al.   LANCET

New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure

(2008) Yu-Hua Tseng et al.   NATURE