Pravastatin Chronic Treatment Sensitizes Hypercholesterolemic Mice Muscle to Mitochondrial Permeability Transition: Protection by Creatine or Coenzyme Q10

Chronic use of pravastatin reduces insulin exocytosis and increases β-cell death in hypercholesterolemic mice

(2016) Estela Lorza-Gil et al.   TOXICOLOGY

Underestimation of the Maximal Capacity of the Mitochondrial Electron Transport System in Oligomycin-Treated Cells

(2016) Juliana S. Ruas et al.   PLoS One

The mechanistic and ergogenic effects of phosphatidic acid in skeletal muscle

(2015) Brandon James Shad et al.   Applied Physiology Nutrition and Metabolism

Statin-Induced Myopathy Is Associated with Mitochondrial Complex III Inhibition

(2015) Tom J.J. Schirris et al.   Cell Metabolism

Rapid Mitogenic Regulation of the mTORC1 Inhibitor, DEPTOR, by Phosphatidic Acid

(2015) Mee-Sup Yoon et al.   MOLECULAR CELL

MetaboAnalyst 3.0—making metabolomics more meaningful

(2015) Jianguo Xia et al.   NUCLEIC ACIDS RESEARCH

Statins and Cancer

(2014) Natalia Vallianou et al.   Anti-Cancer Agents in Medicinal Chemistry

Phospholipase D and the Maintenance of Phosphatidic Acid Levels for Regulation of Mammalian Target of Rapamycin (mTOR)

(2014) David A. Foster et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unraveling the Truth About Antioxidants: Mitohormesis explains ROS-induced health benefits

(2014) Michael Ristow   NATURE MEDICINE

The skeletal muscle arachidonic acid cascade in health and inflammatory disease

(2014) Marina Korotkova et al.   Nature Reviews Rheumatology

Statins role in the prevention and treatment of sepsis

(2014) Paul P. Dobesh et al.   PHARMACOLOGICAL RESEARCH

Statins in neurological disorders: An overview and update

(2014) Anna Maria Malfitano et al.   PHARMACOLOGICAL RESEARCH

Creatine, L-Carnitine, andω3 Polyunsaturated Fatty Acid Supplementation from Healthy to Diseased Skeletal Muscle

(2014) Giuseppe D’Antona et al.   Biomed Research International

Protective effects of l-carnitine and piracetam against mitochondrial permeability transition and PC3 cell necrosis induced by simvastatin

(2013) Rute A.P. Costa et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Ubiquinol rescues simvastatin-suppression of mitochondrial content, function and metabolism: Implications for statin-induced rhabdomyolysis

(2013) Roger A. Vaughan et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Mechanisms of the Statins Cytotoxicity in Freshly Isolated Rat Hepatocytes

(2013) Narges Abdoli et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Simvastatin Effects on Skeletal Muscle

(2013) Steen Larsen et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Comparative benefits of statins in the primary and secondary prevention of major coronary events and all-cause mortality: a network meta-analysis of placebo-controlled and active-comparator trials

(2013) Huseyin Naci et al.   European Journal of Preventive Cardiology

Protection of rat skeletal muscle fibers by either L-carnitine or coenzyme Q10 against statins toxicity mediated by mitochondrial reactive oxygen generation

(2013) P. G. La Guardia et al.   Frontiers in Physiology

Mitochondrial Permeability Transition and Cell Death: The Role of Cyclophilin D

(2013) Sabzali Javadov et al.   Frontiers in Physiology

Effect of Coenzyme Q10 Supplementation on Statin-Induced Myalgias

(2012) David A. Bookstaver et al.   AMERICAN JOURNAL OF CARDIOLOGY

Mitochondria as a Source of Reactive Oxygen and Nitrogen Species: From Molecular Mechanisms to Human Health

(2012) Tiago R. Figueira et al.   ANTIOXIDANTS & REDOX SIGNALING

Impaired Insulin/IGF1 Signaling Extends Life Span by Promoting Mitochondrial L-Proline Catabolism to Induce a Transient ROS Signal

(2012) Kim Zarse et al.   Cell Metabolism

Muscle mitochondrial metabolism and calcium signaling impairment in patients treated with statins

(2012) P. Sirvent et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Characterization of Fiber Types in Different Muscles of the Hindlimb in Female Weanling and Adult Wistar Rats

(2011) Anabelle Silva Cornachione et al.   ACTA HISTOCHEMICA ET CYTOCHEMICA

Mitochondrial permeability transition in Ca2+-dependent apoptosis and necrosis

(2011) Andrea Rasola et al.   CELL CALCIUM

Cross talk between mitochondria and NADPH oxidases

(2011) Sergey Dikalov   FREE RADICAL BIOLOGY AND MEDICINE

Simvastatin impairs ADP-stimulated respiration and increases mitochondrial oxidative stress in primary human skeletal myotubes

(2011) Hyo-Bum Kwak et al.   FREE RADICAL BIOLOGY AND MEDICINE

Age-related changes in skeletal muscle reactive oxygen species generation and adaptive responses to reactive oxygen species

(2011) Malcolm J. Jackson et al.   JOURNAL OF PHYSIOLOGY-LONDON

Simvastatin treatment prevents oxidative damage to DNA in whole blood leukocytes of dyslipidemic type 2 diabetic patients

(2010) Vanusa Manfredini et al.   CELL BIOCHEMISTRY AND FUNCTION

Pleiotropic Effects of Statins

(2010) Qian Zhou et al.   CIRCULATION JOURNAL

Calcium Signalling: Fishing Out Molecules of Mitochondrial Calcium Transport

(2010) György Hajnóczky et al.   CURRENT BIOLOGY

New insights into mechanisms of statin-associated myotoxicity

(2008) P SIRVENT et al.   CURRENT OPINION IN PHARMACOLOGY

Simvastatin inducing PC3 prostate cancer cell necrosis mediated by calcineurin and mitochondrial dysfunction

(2008) Kívia A. P. Oliveira et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Analysis of mitochondrial function in situ in permeabilized muscle fibers, tissues and cells

(2008) Andrey V Kuznetsov et al.   Nature Protocols