The Histamine H3 Receptor Antagonist E159 Reverses Memory Deficits Induced by Dizocilpine in Passive Avoidance and Novel Object Recognition Paradigm in Rats

Thujone inhibits the function of α 7 -nicotinic acetylcholine receptors and impairs nicotine-induced memory enhancement in one-trial passive avoidance paradigm

(2017) Ahmed Sultan et al.   TOXICOLOGY

Histamine H3 receptor as a potential target for cognitive symptoms in neuropsychiatric diseases

(2016) Bassem Sadek et al.   BEHAVIOURAL BRAIN RESEARCH

The dual-acting H3 receptor antagonist and AChE inhibitor UW-MD-71 dose-dependently enhances memory retrieval and reverses dizocilpine-induced memory impairment in rats

(2016) Nadia Khan et al.   BEHAVIOURAL BRAIN RESEARCH

Effects of Xiaoyaosan on Stress-Induced Anxiety-Like Behavior in Rats: Involvement of CRF1 Receptor

(2016) You-Ming Jiang et al.   Evidence-based Complementary and Alternative Medicine

Anticonvulsant and procognitive properties of the non-imidazole histamine H3 receptor antagonist DL77 in male adult rats

(2016) Bassem Sadek et al.   NEUROPHARMACOLOGY

Cherry-picked ligands at histamine receptor subtypes

(2016) Bassem Sadek et al.   NEUROPHARMACOLOGY

Donepezil, an acetylcholine esterase inhibitor, and ABT-239, a histamine H 3 receptor antagonist/inverse agonist, require the integrity of brain histamine system to exert biochemical and procognitive effects in the mouse

(2016) Gustavo Provensi et al.   NEUROPHARMACOLOGY

The dual-acting AChE inhibitor and H 3 receptor antagonist UW-MD-72 reverses amnesia induced by scopolamine or dizocilpine in passive avoidance paradigm in rats

(2016) Bassem Sadek et al.   PHYSIOLOGY & BEHAVIOR

Anticonvulsant effects of isomeric nonimidazole histamine H3 receptor antagonists

(2016) Bassem Sadek et al.   Drug Design Development and Therapy

Non-imidazole-based histamine H3 receptor antagonists with anticonvulsant activity in different seizure models in male adult rats

(2016) Bassem Shaban Sadek et al.   Drug Design Development and Therapy

Interaction between anti-Alzheimer and antipsychotic drugs in modulating extrapyramidal motor disorders in mice

(2015) Saki Shimizu et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Alzheimer's disease, enzyme targets and drug discovery struggles: From natural products to drug prototypes

(2014) Tiago Silva et al.   AGEING RESEARCH REVIEWS

Histaminergic system in brain disorders: lessons from the translational approach and future perspectives

(2014) Diego Baronio et al.   Annals of General Psychiatry

The prototypical histamine H3 receptor inverse agonist thioperamide improves multiple aspects of memory processing in an inhibitory avoidance task

(2013) Yana Charlier et al.   BEHAVIOURAL BRAIN RESEARCH

The histamine H3-receptor inverse agonist Pitolisant improves fear memory in mice

(2013) Christian Brabant et al.   BEHAVIOURAL BRAIN RESEARCH

Histamine infused into basolateral amygdala enhances memory consolidation of inhibitory avoidance

(2013) Fernando Benetti et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

The effect of ghrelin on MK-801 induced memory impairment in rats

(2013) Fatemeh Goshadrou et al.   PEPTIDES

Histamine H3receptor antagonists in relation to epilepsy and neurodegeneration: a systemic consideration of recent progress and perspectives

(2012) M Bhowmik et al.   BRITISH JOURNAL OF PHARMACOLOGY

Histaminergic ligands injected into the nucleus basalis magnocellularis differentially affect fear conditioning consolidation

(2012) Fernando Benetti et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Preclinical evaluation of non-imidazole histamine H3 receptor antagonists in comparison to atypical antipsychotics for the treatment of cognitive deficits associated with schizophrenia

(2012) Jordan W. Brown et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

SAR110894, a potent histamine H3-receptor antagonist, displays procognitive effects in rodents

(2012) Guy Griebel et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Bodilisant—A Novel Fluorescent, Highly Affine Histamine H3 Receptor Ligand

(2012) Miriam Tomasch et al.   ACS Medicinal Chemistry Letters

Putative cognitive enhancers in preclinical models related to schizophrenia: The search for an elusive target

(2011) Segev Barak et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Histamine receptors in the CNS as targets for therapeutic intervention

(2011) Maria Beatrice Passani et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Beneficial interaction between clobenpropit and pyridoxine in prevention of electroshock-induced seizures in mice: Lack of histaminergic mechanisms

(2010) P. Uma Devi et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Discovery of Histamine H3 Antagonists for the Treatment of Cognitive Disorders and Alzheimer's Disease

(2010) J. D. Brioni et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Ciproxifan, an H3 receptor antagonist, alleviates hyperactivity and cognitive deficits in the APPTg2576 mouse model of Alzheimer’s disease

(2010) Mark E. Bardgett et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Once-monthly paliperidone injection for the treatment of schizophrenia

(2010) Delia Bishara   Neuropsychiatric Disease and Treatment

Fluorinated non-imidazole histamine H3 receptor antagonists

(2009) K. Isensee et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Characterization of histamine H3 receptors in Alzheimer's Disease brain and amyloid over-expressing TASTPM mice

(2009) AD Medhurst et al.   BRITISH JOURNAL OF PHARMACOLOGY

Regional Differential Effects of the Novel Histamine H3 Receptor Antagonist 6-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-N-methyl-3-pyridinecarboxamide hydrochloride (GSK189254) on Histamine Release in the Central Nervous System of Freely Moving Rats

(2009) P. Giannoni et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The neonatal ventral hippocampal lesion as a heuristic neurodevelopmental model of schizophrenia

(2008) Kuei Y. Tseng et al.   BEHAVIOURAL BRAIN RESEARCH

Potential utility of histamine H3 receptor antagonist pharmacophore in antipsychotics

(2008) Y. von Coburg et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The histamine H3receptor: an attractive target for the treatment of cognitive disorders

(2008) T A Esbenshade et al.   BRITISH JOURNAL OF PHARMACOLOGY

Multi-target-Directed Ligands To Combat Neurodegenerative Diseases

(2008) Andrea Cavalli et al.   JOURNAL OF MEDICINAL CHEMISTRY

MK801- and scopolamine-induced amnesias are reversed by an Amazonian herbal locally used as a “brain tonic”

(2008) Adriana Lourenço da Silva et al.   PSYCHOPHARMACOLOGY

Effects of the H3 receptor inverse agonist thioperamide on cocaine-induced locomotion in mice: role of the histaminergic system and potential pharmacokinetic interactions

(2008) Christian Brabant et al.   PSYCHOPHARMACOLOGY

Drug enhancement of memory consolidation: historical perspective and neurobiological implications

(2008) James L. McGaugh et al.   PSYCHOPHARMACOLOGY

H3 receptor antagonists reverse delay-dependent deficits in novel object discrimination by enhancing retrieval

(2008) Vincent Pascoli et al.   PSYCHOPHARMACOLOGY

d-Serine and a glycine transporter inhibitor improve MK-801-induced cognitive deficits in a novel object recognition test in rats

(2007) Jun-ichi Karasawa et al.   BEHAVIOURAL BRAIN RESEARCH