Extracts of Immature Orange (Aurantii fructus immaturus) and Citrus Unshiu Peel (Citri unshiu pericarpium) Induce P-Glycoprotein and Cytochrome P450 3A4 Expression via Upregulation of Pregnane X Receptor

An Extract of Chinpi, the Dried Peel of the Citrus Fruit Unshiu, Enhances Axonal Remyelination via Promoting the Proliferation of Oligodendrocyte Progenitor Cells

(2016) Hideaki Tokunaga et al.   Evidence-based Complementary and Alternative Medicine

Simultaneous evaluation of human CYP3A4 and ABCB1 induction by reporter assay in LS174T cells, stably expressing their reporter genes

(2015) Keita Inami et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Downregulation of CYP3A and P-Glycoprotein in the Secondary Inflammatory Response of Mice With Dextran Sulfate Sodium–Induced Colitis and Its Contribution to Cyclosporine A Blood Concentrations

(2014) Shoji Kawauchi et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Da-Chaihu-Tang alters the pharmacokinetics of nifedipine in rats and a treatment regimen to avoid this

(2014) Ju-Xiu He et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Analysis of flavonoids regulating the expression of UGT1A1viaxenobiotic receptors in intestinal epithelial cells

(2013) Yuto Hiura et al.   BIOFACTORS

Considerations regarding use of solvents in in vitro cell based assays

(2013) Michael Timm et al.   CYTOTECHNOLOGY

Effect of Chinese herbs on CYP3A4 activity and expression in vitro

(2013) C. Lau et al.   JOURNAL OF ETHNOPHARMACOLOGY

PXR/CYP3A4-Humanized Mice for Studying Drug–Drug Interactions Involving Intestinal P-Glycoprotein

(2013) Nico Holmstock et al.   MOLECULAR PHARMACEUTICS

Evaluation of First-Pass Cytochrome P4503A (CYP3A) and P-glycoprotein Activities Using Felodipine and Hesperetin in Combination in Wistar Rats and Everted Rat Gut Sacsin Vitro

(2013) V. Sridhar et al.   PHYTOTHERAPY RESEARCH

Expression of the PXR gene in various types of cancer and drug resistance

(2013) ENQI QIAO et al.   Oncology Letters

Byakangelicin induces cytochrome P450 3A4 expression via transactivation of pregnane X receptors in human hepatocytes

(2010) Jian Yang et al.   BRITISH JOURNAL OF PHARMACOLOGY

PXR-mediated induction of P-glycoprotein by anticancer drugs in a human colon adenocarcinoma-derived cell line

(2009) Stefan Harmsen et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Experimental Adjustment on Drug Interactions through Intestinal CYP3A Activity in Rat: Impacts of Kampo Medicines Repeat Administered

(2009) Natsumi Kinoshita et al.   Evidence-based Complementary and Alternative Medicine

Association of Pregnane X Receptor with Multidrug Resistance-Related Protein 3 and its Role in Human Colon Cancer Chemoresistance

(2009) Heng Jiang et al.   JOURNAL OF GASTROINTESTINAL SURGERY

Intestinal Human Colon Adenocarcinoma Cell Line LS180 Is an Excellent Model to Study Pregnane X Receptor, but Not Constitutive Androstane Receptor, Mediated CYP3A4 and Multidrug Resistance Transporter 1 Induction: Studies with Anti-Human Immunodeficiency Virus Protease Inhibitors

(2008) A. Gupta et al.   DRUG METABOLISM AND DISPOSITION

Activation of Pregnane X Receptor and Induction of MDR1 by Dietary Phytochemicals

(2008) Hideo Satsu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY