Altered CYP19A1 and CYP3A4 Activities Due to Mutations A115V, T142A, Q153R and P284L in the Human P450 Oxidoreductase

Impact on CYP19A1 activity by mutations in NADPH cytochrome P450 oxidoreductase

(2017) Christa E. Flück et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

P450 Oxidoreductase deficiency: Analysis of mutations and polymorphisms

(2017) Fabian Z. Burkhard et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Vitamin D-Dependent Rickets Type 1 Caused by Mutations in CYP27B1 Affecting Protein Interactions With Adrenodoxin

(2016) Adam Zalewski et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

P450 Oxidoreductase Deficiency: Loss of Activity Caused by Protein Instability From a Novel L374H Mutation

(2016) Shaheena Parween et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Steroidogenesis of the testis – new genes and pathways

(2014) Christa E. Flück et al.   ANNALES D ENDOCRINOLOGIE

Pharmacogenomics of human P450 oxidoreductase

(2014) Amit V. Pandey et al.   Frontiers in Pharmacology

NADPH P450 oxidoreductase: Structure, function, and pathology of diseases

(2013) Amit V. Pandey et al.   PHARMACOLOGY & THERAPEUTICS

Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation

(2013) Ulrich M. Zanger et al.   PHARMACOLOGY & THERAPEUTICS

Deletion of P399_E401 in NADPH cytochrome P450 oxidoreductase results in partial mixed oxidase deficiency

(2011) Christa E. Flück et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Altered heme catabolism by heme oxygenase-1 caused by mutations in human NADPH cytochrome P450 reductase

(2010) Amit V. Pandey et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Reduction in hepatic drug metabolizing CYP3A4 activities caused by P450 oxidoreductase mutations identified in patients with disordered steroid metabolism

(2010) Christa E. Flück et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Structural diversity of cytochrome P450 enzyme system

(2010) Tsuneo Omura   JOURNAL OF BIOCHEMISTRY

Restoration of mutant cytochrome P450 reductase activity by external flavin

(2010) Catherine Nicolo et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Pharmacogenetics of P450 oxidoreductase: effect of sequence variants on activities of CYP1A2 and CYP2C19

(2010) Vishal Agrawal et al.   Pharmacogenetics and Genomics

Substrate-specific modulation of CYP3A4 activity by genetic variants of cytochrome P450 oxidoreductase

(2010) Vishal Agrawal et al.   Pharmacogenetics and Genomics

Crystal structure of the FMN-binding domain of human cytochrome P450 reductase at 1.93 Å resolution

(2010) Qiang Zhao et al.   PROTEIN SCIENCE

Human Cytochrome P450 Oxidoreductase Deficiency Caused by the Y181D Mutation: Molecular Consequences and Rescue of Defect

(2009) C. C. Marohnic et al.   DRUG METABOLISM AND DISPOSITION

Structure of the open conformation of a functional chimeric NADPH cytochrome P450 reductase

(2009) Louise Aigrain et al.   EMBO REPORTS

Measurement of cytochrome P450 and NADPH–cytochrome P450 reductase

(2009) F Peter Guengerich et al.   Nature Protocols

Nomenclature for alleles of the cytochrome P450 oxidoreductase gene

(2009) Sarah C. Sim et al.   Pharmacogenetics and Genomics

Pharmacogenomics of human liver cytochrome P450 oxidoreductase: multifactorial analysis and impact on microsomal drug oxidation

(2009) Ana M Gomes et al.   PHARMACOGENOMICS

The Common P450 Oxidoreductase Variant A503V Is Not a Modifier Gene for 21-Hydroxylase Deficiency

(2008) Larissa G. Gomes et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Genetics of P450 oxidoreductase: Sequence variation in 842 individuals of four ethnicities and activities of 15 missense mutations

(2008) N. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA