Interleukin-6 Deficiency Attenuates Retinal Ganglion Cell Axonopathy and Glaucoma-Related Vision Loss

The Fluctuation of Intraocular Pressure Measured by a Contact Lens Sensor in Normal-Tension Glaucoma Patients and Nonglaucoma Subjects

(2017) Naoki Tojo et al.   JOURNAL OF GLAUCOMA

Comparison of self-measured diurnal intraocular pressure profiles using rebound tonometry between primary angle closure glaucoma and primary open angle glaucoma patients

(2017) Shaoying Tan et al.   PLoS One

Mice Homozygous for a Deletion in the Glaucoma Susceptibility Locus INK4 Show Increased Vulnerability of Retinal Ganglion Cells to Elevated Intraocular Pressure

(2016) Shan Gao et al.   AMERICAN JOURNAL OF PATHOLOGY

Virus-mediated EpoR76E gene therapy preserves vision in a glaucoma model by modulating neuroinflammation and decreasing oxidative stress

(2016) Jessica Hines-Beard et al.   Journal of Neuroinflammation

Boosting Central Nervous System Axon Regeneration by Circumventing Limitations of Natural Cytokine Signaling

(2016) Marco Leibinger et al.   MOLECULAR THERAPY

Virus-mediated EpoR76E Therapy Slows Optic Nerve Axonopathy in Experimental Glaucoma

(2016) Wesley S Bond et al.   MOLECULAR THERAPY

Multiplex cytokine levels of aqueous humor in acute primary angle-closure patients: fellow eye comparison

(2016) Shaolin Du et al.   BMC Ophthalmology

Early pro-inflammatory cytokine elevations in the DBA/2J mouse model of glaucoma

(2015) Gina N. Wilson et al.   Journal of Neuroinflammation

Microglia-induced IL-6 protects against neuronal loss following HSV-1 infection of neural progenitor cells

(2014) Ana J. Chucair-Elliott et al.   GLIA

The effect of previous surgery and topical eye drops for primary open-angle glaucoma on cytokine expression in aqueous humor

(2014) Lisa A. Engel et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Microglia in mouse retina contralateral to experimental glaucoma exhibit multiple signs of activation in all retinal layers

(2014) Blanca Rojas et al.   Journal of Neuroinflammation

Absence of Transient Receptor Potential Vanilloid-1 Accelerates Stress-Induced Axonopathy in the Optic Projection

(2014) N. J. Ward et al.   JOURNAL OF NEUROSCIENCE

Central inhibition of interleukin-6 trans-signaling during peripheral infection reduced neuroinflammation and sickness in aged mice

(2013) Michael D. Burton et al.   BRAIN BEHAVIOR AND IMMUNITY

Interleukin-6 contributes to CNS axon regeneration upon inflammatory stimulation

(2013) M Leibinger et al.   Cell Death & Disease

Neuroprotection of Interleukin-6 Against NMDA-induced Neurotoxicity is Mediated by JAK/STAT3, MAPK/ERK, and PI3K/AKT Signaling Pathways

(2012) Xiao-Xia Fang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

The effects of anesthesia, mouse strain and age on intraocular pressure and an improved murine model of experimental glaucoma

(2012) Frances E. Cone et al.   EXPERIMENTAL EYE RESEARCH

Interleukin-6, a Major Cytokine in the Central Nervous System

(2012) María Erta et al.   International Journal of Biological Sciences

IOP induces upregulation of GFAP and MHC-II and microglia reactivity in mice retina contralateral to experimental glaucoma

(2012) Beatriz I Gallego et al.   Journal of Neuroinflammation

Interleukin-6 is an efficacious marker of axonal transport disruption during experimental glaucoma and stimulates neuritogenesis in cultured retinal ganglion cells

(2012) Glyn Chidlow et al.   NEUROBIOLOGY OF DISEASE

IL6 Protects MN9D Cells and Midbrain Dopaminergic Neurons from MPP+-Induced Neurodegeneration

(2012) Björn Spittau et al.   NEUROMOLECULAR MEDICINE

Failure of axonal transport induces a spatially coincident increase in astrocyte BDNF prior to synapse loss in a central target

(2012) S.D. Crish et al.   NEUROSCIENCE

Critical pathogenic events underlying progression of neurodegeneration in glaucoma

(2012) David J. Calkins   PROGRESS IN RETINAL AND EYE RESEARCH

Risk Factors for Visual Field Progression in Treated Glaucoma

(2011) Carlos Gustavo V. De Moraes   ARCHIVES OF OPHTHALMOLOGY

Interleukin-6 trans-signaling in the senescent mouse brain is involved in infection-related deficits in contextual fear conditioning

(2011) Michael D. Burton et al.   BRAIN BEHAVIOR AND IMMUNITY

Inhibition of interleukin-6 trans-signaling in the brain facilitates recovery from lipopolysaccharide-induced sickness behavior

(2011) Michael D Burton et al.   Journal of Neuroinflammation

Brimonidine prevents axonal and somatic degeneration of retinal ganglion cell neurons

(2011) Wendi S Lambert et al.   Molecular Neurodegeneration

Differential susceptibility to experimental glaucoma among 3 mouse strains using bead and viscoelastic injection

(2010) Frances E. Cone et al.   EXPERIMENTAL EYE RESEARCH

Anti-IL-6-receptor antibody promotes repair of spinal cord injury by inducing microglia-dominant inflammation

(2010) Masahiko Mukaino et al.   EXPERIMENTAL NEUROLOGY

Early microglia activation in a mouse model of chronic glaucoma

(2010) Alejandra Bosco et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Differences in Wound Healing in Mice with Deficiency of IL-6 versus IL-6 Receptor

(2010) M. M. McFarland-Mancini et al.   JOURNAL OF IMMUNOLOGY

Distal axonopathy with structural persistence in glaucomatous neurodegeneration

(2010) S. D. Crish et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Friend or Foe? Resolving the Impact of Glial Responses in Glaucoma

(2009) Elaine C. Johnson et al.   JOURNAL OF GLAUCOMA

IL-6 Promotes compensatory liver regeneration in cirrhotic rat after partial hepatectomy

(2008) Guido A.M. Tiberio et al.   CYTOKINE