Article
Chemistry, Medicinal
Yaxin Chen, Niaoniao He, Ting Yang, Shuyun Cai, Yi Zhang, Jinjing Lin, Mingqing Huang, Weizhu Chen, Yiping Zhang, Zhuan Hong
Summary: In this study, a solid lipid nanoparticle-microcapsule delivery system was creatively constructed to encapsulate fucoxanthin (FX), aiming to improve its stability and bioavailability. The encapsulated FX showed higher storage stability, sustained release, and significantly improved bioavailability compared to free FX. The research results provide a theoretical basis for the development and application of FX in pharmaceuticals or functional foods.
Article
Agriculture, Multidisciplinary
Pimwalan Ornla-ied, Pawitchaya Podchong, Sopark Sonwai
Summary: Chemical interesterification is an important process for producing zero-trans fats, and in this study, trans-free cocoa butter alternatives were successfully produced from palm kernel stearin, coconut oil, and fully-hydrogenated palm stearin blends via this process. The structured lipids obtained from blends containing 60-70% palm kernel stearin showed properties most similar to commercial CBAs, making them a promising option for the confectionery industry.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2022)
Article
Chemistry, Applied
Liting Wan, Lin Li, Xia Zhang, Bing Li, Janette M. Harro, Mark E. Shirtliff
Summary: This study aimed to investigate the impacts of dietary lipid composition and content on the cecal and fecal microbiota in mice. The results showed that increasing the dietary palm stearin (PS) level promoted the growth of Firmicutes and resulted in higher lipid and bile acid content in feces. However, increasing palm olein (PO) intake did not affect the microbial structure. Only at a high-fat level, PS (compared to PO) induced the observed microbial shifts. These findings highlight the importance of both lipid quality and quantity on gut microbiota.
Article
Food Science & Technology
Ngatirah Ngatirah, Chusnul Hidayat, Endang S. Rahayu, Tyas Utami
Summary: This study prepared monolaurin through enzymatic glycerolysis and investigated the effects of various factors on the products of glycerolysis. The purified monolaurin showed good emulsion capacity and stability, as well as antibacterial properties.
Article
Chemistry, Applied
Pimwalan Ornla-ied, Chin Ping Tan, Yong Wang, Sopark Sonwai
Summary: Structured lipids produced from enzymatic interesterification of fat blends showed altered triglyceride compositions, resulting in changes in physical properties and crystallization behavior. The SFC and slip melting point of SL were lower compared to their physical blends, with some SL blends having potential to be used as trans-free cocoa butter alternatives.
JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY
(2021)
Article
Chemistry, Applied
Yuying Zhao, Jinglei Zhi, Shuyao Huang, Xin Zhang, Young-Rok Kim, Ying Xu, Dongfeng Wang, Ke Luo
Summary: In this study, an effective method for encapsulating the hydrophobic bioactive fucoxanthin within starch-based microparticles was developed. The use of short-chain glucans and zein nanoparticles as intermediate vectors contributed to higher encapsulation efficiency and improved stability of the fucoxanthin. The starch-based microparticles also exhibited controlled release, making them a potential carrier for delivering hydrophobic bioactives to different parts of the intestine.
Article
Chemistry, Applied
Sanying Wang, Xiaogang Xu, Chuan Sun, Jing Zhang, Xinyue He, Zhongshan Zhang, Hong Huang, Jing Yan, Weihua Jin, Genxiang Mao
Summary: The research demonstrated that the degree of sulphation and polymerization is crucial for anti-HCMV activity, with higher sulphated glucuronomannan tetramer and hexamer showing satisfactory results. Furthermore, sulphated glucuronomannan oligosaccharides can exert their anti-HCMV activity mainly in the early stage of infection through the negative charge of the sulphate groups and interaction with host cells.
CARBOHYDRATE POLYMERS
(2021)
Article
Multidisciplinary Sciences
Miftakhur Rohmah, Anton Rahmadi, Sri Raharjo
Summary: Beta-carotene is an essential nutrient with antioxidant, anticancer, and anti-inflammatory properties; however, its absorption level in the digestive tract is low due to its high hydrophobicity. This study evaluated the use of nanostructured lipid carriers to enhance the bioaccessibility and antioxidant activity of beta-carotene. The results suggested that the formulated nanostructured lipid carrier system can effectively deliver lipophilic bioactives like beta-carotene in beverage products.
Article
Food Science & Technology
Dahee Kim, Jing Yan, Jinwoo Bak, Jumin Park, Heeseob Lee, Hyemee Kim
Summary: The ethanol extract from Sargassum thunbergii showed anti-obesity effects by regulating AMPK activation and gut microbiota composition, preventing weight gain and improving metabolic health in high-fat diet-fed mice.
Article
Environmental Sciences
Guo-Ning Nan, Xiao-Qun Zhou, Xiu-Mei Zhang, Quan-Sheng Zhang, Zi-Min Hu, Rui-Ping Huang, Di Zhang
Summary: This study demonstrates that xanthophyll cycle-induced non-photochemical quenching (NPQ) can effectively protect Sargassum thunbergii from light fluctuations in the intertidal zone.
FRONTIERS IN MARINE SCIENCE
(2022)
Article
Agriculture, Multidisciplinary
Chao Lu, Shuang Qiu, Xueping Wang, Xinyi He, Leping Dang, Zhanzhong Wang
Summary: Novel layer melt crystallization was successfully applied and optimized for fractionating palm oil, with the composition and property changes of obtained fractions being analyzed and explained at both macroscopic and microscopic levels.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2021)
Article
Biodiversity Conservation
Zhibo Yang, Tao Sun, Jun Chen, Jing Wang, Xinlong Yu, Yayun Zhao, Yang Li, Xuexi Tang, Hui Xiao
Summary: This study investigated the epiphytic bacterial communities on different tissues (tip, receptacle, and holdfast) of male and female Sargassum thunbergii. The results showed tissue and sex specificity of the epiphytic bacteria, with significant differences from seawater bacterial samples. The study revealed that algal tissue location contributed more than host sex to the assembly of epiphytic bacterial communities, and the contributions of these two factors varied among tissues.
ECOLOGICAL INDICATORS
(2023)
Article
Biotechnology & Applied Microbiology
Jing Wang, Zhibo Yang, Gaoge Wang, Shuai Shang, Xuexi Tang, Hui Xiao
Summary: This study investigated the composition and diversity of epiphytic bacterial communities on male and female Sargassum thunbergii using traditional culture-based method and 16S rDNA high-throughput sequencing. The results showed that the dominant bacterial phyla and genera were the same on both male and female S. thunbergii, but there were significant differences in the relative abundance of epiphytic bacteria at the genus level. Moreover, each sex had their own indicative species and specific bacteria, and the predicted functions of the epiphytic bacteria differed between the sexes.
Article
Environmental Sciences
Zhi-Fang Zhao, Zhong-Jian Huang, Zuo-Deng Sun, Zheng-Yi Liu, Song Qin, Tong Han, Xin-Yu Qi, Xi-Yan Sun, Zhi-Hai Zhong
Summary: Few studies have investigated the dynamics of dissolved organic carbon (DOC) release in macroalgae. This study examined the short-term changes in temperature, light, and salinity on DOC release in Sargassum thunbergii. The results showed that different levels of photosynthetically active radiation, salinity, and temperature all influenced the rate of DOC release in S. thunbergii.
MARINE POLLUTION BULLETIN
(2023)
Article
Engineering, Environmental
Hao Chen, Yi Zhang, Kai Gao, Yilong Ren, Jianguo Jiao, Lin Zhang, Dan Guo, Guoxin Xie
Summary: In this study, heat-resisting solid-liquid compound microcapsules were prepared using thermostable SiO2 as the shell and WS2 silicone oil dispersion as the core. The microcapsule composites exhibited excellent tribological properties and low wear rates at high temperatures due to the combination of SiO2's mechanical properties and WS2's lubricating function. The proposed strategy is expected to be a general solution for enhancing high-temperature lubrication properties in polymer composites by incorporating microcapsules with different solid-liquid cores.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Applied
Chang Su, Xiaojie Sun, Yuzhi Mu, Piwu Li, Jing Li, Pengsheng Fan, Mengxue Zhang, Mengyang Wang, Xiguang Chen, Chao Feng
Summary: A multilayer calcium alginate beads were designed for sewage treatment, combining organic matter degradation and metal ions absorption, which significantly improves the efficiency of wastewater treatment.
CARBOHYDRATE POLYMERS
(2021)
Article
Biochemistry & Molecular Biology
Xiaojie Sun, Jing Li, Kai Shao, Chang Su, Shichao Bi, Yuzhi Mu, Kaichao Zhang, Zheng Cao, Xiaoye Wang, Xiguang Chen, Chao Feng
Summary: The AC-DB sponge demonstrated rapid hemostatic ability and good biocompatibility, activating intrinsic coagulation pathway to accelerate clotting process, with shortest clotting time and minimal blood loss in vivo assessments.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Multidisciplinary
Xin Cong, Yuzhi Mu, Di Qin, Xiaojie Sun, Chang Su, Tongtong Chen, Xiaoye Wang, Xiguang Chen, Chao Feng
Summary: A new Cu-DBs developed for infected wound therapy showed enhanced photothermal and photodynamic performance, achieving high antibacterial efficiency and promoting wound healing effectively.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Biotechnology & Applied Microbiology
Tongtong Chen, Feifei Wu, Yang Li, Hussein E. Rozan, Xiguang Chen, Chao Feng
Summary: A label-free photoluminescence immune-detection platform based on functionalized diatom frustules was developed, showing high sensitivity and a wide detection range. The platform has the potential for sensitive quantitative analysis.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Chemistry, Applied
Zheng Cao, Chang Su, Xiaojie Sun, Kai Shao, Xiaoye Wang, Yuzhi Mu, Xiguang Chen, Chao Feng
Summary: The temperature-sensitive hydrogel composed of diatom biosilica and hydroxybutyl chitosan shows significantly enhanced mechanical strength and favorable blood compatibility and biocompatibility. By adjusting the ratio of diatom biosilica and hydroxybutyl chitosan, the properties of the hydrogel can be flexibly controlled.
CARBOHYDRATE POLYMERS
(2022)
Article
Nanoscience & Nanotechnology
Xiaoye Wang, Yuzhi Mu, Kuikun Yang, Kai Shao, Xin Cong, Zheng Cao, Xiaojie Sun, Chang Su, Xiguang Chen, Chao Feng
Summary: In this study, we proposed a novel solution for reversible regulation of reactive oxygen species (ROS) levels using a semiconductor heterojunction. By integrating two metal-based ROS scavengers, a n-type CeO2 nanoparticles and a n-type Cu-doped diatom biosilica, a cascade catalytic reaction was activated to quickly eliminate ROS, while a near-infrared (NIR)-triggered photocatalytic effect switched to ROS generation. This reversible ROS regulation system provided a noninvasive strategy for controlling ROS levels both in vitro and in vivo, which can relieve cellular oxidative stress and inhibit bacterial growth.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Biophysics
Chang Su, Changqing Jiang, Xiaojie Sun, Zheng Cao, Yuzhi Mu, Xin Cong, Kaijin Qiu, Jiawen Lin, Xiguang Chen, Chao Feng
Summary: This study developed diatomite hemostatic granules through rotating granulation method, which showed rapid hemostatic ability and good biocompatibility. The granules retained the porous structure of diatomite, exhibited strong clotting ability, and had no side effects.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Engineering, Multidisciplinary
Di Qin, Xinguo You, Haonan Wang, Yixuan Liu, Yan Shi, Na Wang, Xin Zhang, Chao Feng, Ya Liu, Ming Kong, Xiaojie Cheng, Shichao Bi, Xiguang Chen
Summary: Surface topography of fish scales promotes bone regeneration by directing cell behavior and modulating the osteoimmune microenvironment. The anisotropic ridged micropatterns and mineralized collagen on the scales induce macrophage polarization and stimulate anti-inflammatory cytokine secretion. In addition, they enhance osteogenic differentiation of mesenchymal stem cells and increase bone formation. The findings suggest that fish scales can be a potential implant material for bone repair.
COMPOSITES PART B-ENGINEERING
(2023)
Article
Engineering, Biomedical
Xu Qiu, Chao Feng, Wenxuan Wang, Guangsheng Wu, Yingzhe Hu, Shuhan Li, Xiangru Gao, Xiguang Chen, Qiuxia Ji
Summary: This study demonstrated that copper-deposited Diatom-biosilica (Cu-DBs) have the potential to repair bone defects caused by inflammation. Cu-DBs promoted osteogenesis and angiogenesis, as well as inhibited inflammatory responses and reduced immune cell infiltration. In vitro and in vivo experiments confirmed the osteogenic properties of Cu-DBs. The unique chemical characteristics of Cu2+ and Si4+ ions enhanced the osteogenic differentiation of periodontal ligament stem cells and stimulated osteogenesis in rats.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
(2023)
Article
Biotechnology & Applied Microbiology
Chenfei Yang, Chao Feng, Yuhang Li, Zheng Cao, Yan Sun, Xiaohui Li, Lin Zhang, Chengxu Zhou, Jichang Han
Summary: Diatoms, with their silicified cell wall known as frustule, are crucial to marine primary production. The frustule provides various benefits to diatoms, including nutrient uptake, UV protection, predator deterrent, parasite resistance, light harvesting, CO2 capture, and position control. Moreover, as an exquisite biosilica, the frustule holds great potential as bionanomaterials in the biomedical field. This review explores the morphological and physicochemical characteristics of the frustule, as well as its biological functions and biomedical applications.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
(2023)
Article
Chemistry, Multidisciplinary
Xiaojie Sun, Na Li, Chang Su, Yuzhi Mu, Xin Cong, Zheng Cao, Xiaoye Wang, Xiaoyan Yang, Xiguang Chen, Chao Feng
Summary: In this study, a diatom-inspired bionic hydrophilic polysaccharide adhesive was developed for rapid hemostasis. The adhesive exhibited strong mechanical strength and viscosity, and maintained adhesion ability in wet environments. The dry adhesive prepared by lyophilization also showed excellent clotting ability for anticoagulant whole blood.
Article
Chemistry, Physical
Chang Su, Zheng Cao, Jiahao Liu, Xiaojie Sun, Kaijin Qiu, Yuzhi Mu, Xin Cong, Xiaoye Wang, Xiguang Chen, Nan Jia, Chao Feng
Summary: We developed a Ca2+ modified diatom biosilica-based hemostat (DBp-Ca2+) with a hierarchical porous structure. The unique porous size arrangement of DBp-Ca2+ allows for selective adsorption during coagulation process, resulting in rapid hemorrhage control. In vitro and in vivo studies confirmed that DBp-Ca2+ has high porosity, water absorption, protein absorption, and can accelerate blood exchange and reduce thrombosis time.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Marine & Freshwater Biology
Qinfeng Li, Zheng He, Hussein. E. Rozan, Chao Feng, Xiaojie Cheng, Xiguang Chen
Summary: The influence of Ca2+ biomineralization on diatom biosilica (DBs) was explored to develop fast hemostatic materials with a low hemolysis rate. Ca-DBs-3 exhibited good biocompatibility, rapid hemostatic effect, and non-hemolysis, making it a potential candidate for diatom biosilica hemostatic materials.
MARINE LIFE SCIENCE & TECHNOLOGY
(2023)
Review
Chemistry, Multidisciplinary
Xiaojie Sun, Mengxue Zhang, Jinfeng Liu, Guangyan Hui, Xiguang Chen, Chao Feng
Summary: Diatom biosilica is a natural inorganic material with a micro-nanoporous structure and has great application potential in drug delivery, hemostat materials, and biosensors. Manipulating the micro-nanostructure of diatom biosilica through biological regulation methods can transform the screening mode of its structural features and maximize its possibility as a biological material.
Article
Materials Science, Biomaterials
Xiaojie Sun, Na Li, Xiaolei Wang, Yuzhi Mu, Chang Su, Xin Cong, Xiaoye Wang, Feifei Wu, Guangsheng Wu, Xiguang Chen, Chao Feng
Summary: In this study, a hybrid hemostatic gauze (MG-PEG) was prepared by template method for hemorrhage control. It exhibited superior hemostatic performance and wider indications range for practical application.
BIOMATERIALS ADVANCES
(2022)
