Article
Surgery
Nadia Russolillo, Alessandro Borello, Serena Langella, Michele Casella, Roberto Lo Tesoriere, Alessandro Ferrero
Summary: The study showed that preoperative MRI in CRLMs patients undergoing LLR can predict liver metastases, while LUS can additionally detect new nodules, helping adjust surgical strategy and improve accuracy.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Oncology
Huapyong Kang, Seung-seob Kim, Min Je Sung, Jung Hyun Jo, Hee Seung Lee, Moon Jae Chung, Jeong Youp Park, Seung Woo Park, Si Young Song, Mi-Suk Park, Seungmin Bang
Summary: The suitability of the 8th edition AJCC staging system for clinical staging of pancreatic cancer remains uncertain. This study validated the prognostic performance and suitability of the current staging system and found that it is not validated for clinical staging. Separate criteria more suitable for clinical staging should be considered.
Article
Oncology
Alexander B. J. Borgstein, Kammy Keywani, Wietse J. Eshuis, Mark I. van Berge Henegouwen, Suzanne S. Gisbertz
Summary: This study determined the value of staging laparoscopy in patients with advanced gastric cancer in a Western population, showing high accuracy in detecting non-curable disease and avoiding futile treatment.
Article
Radiology, Nuclear Medicine & Medical Imaging
Yan Zhang, Xia Zhang, Jie Li, Qian Cai, Zhi Qiao, Yu kun Luo
Summary: CEUS is a more valuable and non-invasive imaging modality compared to conventional US in detecting extracapsular extension in papillary thyroid carcinoma. Single capsular invasion was a poor predictor of cervical lymph node metastasis, while extracapsular extension assessments were clinically significant for predicting cervical lymph node metastasis. Among the thyroid papillary carcinoma nodules with differential enhancement, hyper-enhanced nodules had the highest incidence of single capsule invasion (41.9%), while hypo-enhanced ones had a higher incidence of ECE (47.4%).
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Lucia Manganaro, Yulia Lakhman, Nishat Bharwani, Benedetta Gui, Silvia Gigli, Valeria Vinci, Stefania Rizzo, Aki Kido, Teresa Margarida Cunha, Evis Sala, Andrea Rockall, Rosemarie Forstner, Stephanie Nougaret
Summary: The ESUR female pelvic imaging working group updated their recommendations in 2019 based on >= 80% consensus among experts, highlighting the main role of MRI in initial staging, response monitoring, and evaluation of disease recurrence, while emphasizing the importance of whole-body FDG-PET in detecting lymph nodes and distant metastases.
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Lifang Jin, Ruitao Wang, Lingling Zhuang, Yubiao Jin, Xing Sun, Chao Jia, Lizhou Lin, Qiusheng Shi, Weituo Zhang, Lianfang Du
Summary: This study evaluated the whole axillary status of breast cancer patients using lymphatic contrast-enhanced ultrasound (LCEUS), and found LCEUS to be an accurate method for observing the entire axilla. Compared to conventional ultrasound and SLNs evaluation, LCEUS had higher diagnostic sensitivity, specificity, and accuracy when used for assessing the whole axilla.
EUROPEAN RADIOLOGY
(2022)
Article
Acoustics
K. Palsdottir, S. Fridsten, L. Blomqvist, Z. Alagic, D. Fischerova, A. Gaurilcikas, K. Hasselrot, F. Jaderling, A. C. Testa, A. Sundin, E. Epstein
Summary: Experienced and less experienced observers showed moderate interobserver agreement for assessing local tumor extension in cervical cancer patients using transvaginal ultrasound (TVS) while MRI observers had moderate-to-good agreement. The level of interobserver agreement was associated with experience among TVS observers only for parametrial invasion.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2021)
Article
Oncology
Alexander B. J. Borgstein, Mark I. van Berge Henegouwen, Wytze Lameris, Wietse J. Eshuis, Suzanne S. Gisbertz
Summary: This study found that staging laparoscopy in gastric cancer patients does not completely avoid surgery, indicating a low sensitivity for detecting metastases or locoregional non-resectability.
Article
Radiology, Nuclear Medicine & Medical Imaging
Najim El Khababi, Regina G. H. Beets-Tan, Renaud Tissier, Max J. Lahaye, Monique Maas, Luis Curvo-Semedo, Raphaela C. Dresen, Joost J. M. van Griethuysen, Stephanie Nougaret, Geerard L. Beets, Baukelien van Triest, Stuart A. Taylor, Doenja M. J. Lambregts
Summary: This study aims to explore the potential impact of a dedicated virtual training course on MRI staging confidence and performance in rectal cancer. The results show that although most of the findings are not statistically significant, there is a mild increase in diagnostic accuracy for most staging variables after completing the course, ranging from +2% to +17%. There is also an improvement in interobserver agreement for almost all variables when comparing the pre- and post-course. The perceived difficulty level decreases significantly after completion of the course, indicating an improved diagnostic confidence.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Zihan Niu, Yuanjing Gao, Mengsu Xiao, Feng Mao, Yidong Zhou, Qingli Zhu, Yuxin Jiang
Summary: This study evaluated the preoperative diagnostic value of contrast-enhanced lymphatic ultrasound (CEUS) for the sentinel lymph node (SLN) status in early breast cancer. The results showed that CEUS demonstrated better diagnostic performance and greater clinical benefits than conventional ultrasound, and had the potential to select candidates for axillary surgery.
EUROPEAN RADIOLOGY
(2023)
Article
Cell Biology
Hui Wang, Shanshan Zhao, Chunyang Xu, Jincao Yao, Xiuhua Yu, Dong Xu
Summary: This study aimed to determine the factors influencing lymph node metastasis (LNM) and develop a more effective method for preoperative N staging assessment. Retrospective analysis of 2130 patients with thyroid cancer who underwent thyroidectomy between 2018 and 2021 was conducted. The study found that serum thyroglobulin was an independent predictor of LNM, and the combined method had a higher diagnostic value for LNM compared to ultrasound alone.
Article
Oncology
Ilaria Capasso, Simone Garzon, Sanjeev Kumar, Amy L. Weaver, Michaela Mc Gree, Luigi Antonio De Vitis, Stefano Uccella, Ivy Petersen, Gretchen Glaser, Carrie Langstraat, Giovanni Scambia, Francesco Fanfani, Andrea Mariani
Summary: This study analyzes the clinicopathological features and outcomes in patients with endometrial cancer with isolated lymphatic recurrence after lymphadenectomy. The results show that low-grade histology and absence of lymphovascular space invasion in the primary tumor are predictors of improved prognosis in these patients. In addition, it is found that patients with isolated lymphatic recurrence who undergo surgical treatment have improved cause-specific survival.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
(2023)
Article
Gastroenterology & Hepatology
Najim El Khababi, Regina G. H. Beets-Tan, Renaud J. Tissier, Max Lahaye, Monique Maas, Luis Curvo-Semedo, Raphaela C. Dresen, Stephanie L. Nougaret, Geerard Beets, Doenja M. J. Lambregts, Rectal MRI Study Grp
Summary: The study aimed to investigate the value of rectal cancer T-staging on MRI in relation to fibrotic transformation of the tumour bed. The results showed that ymrT-staging has moderate accuracy, with higher accuracy in patients with predominant fibrosis. Therefore, radiologists should focus on detecting residual disease and identifying potential candidates for organ preservation.
COLORECTAL DISEASE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Li-Heng Liu, Guo-Feng Zhou, Jian-Jun Zhou, Sheng-Xiang Rao, Meng-Su Zeng
Summary: A lower VAT level is associated with an increased probability of inaccurate clinical T-staging in colon cancer. Lower VAT and proximal tumor location are independent factors contributing to mis-staging.
EUROPEAN JOURNAL OF RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Cui Feng, Yanchun Wang, Guangyu Dan, Zheng Zhong, M. Muge Karaman, Zhen Li, Daoyu Hu, Xiaohong Joe Zhou
Summary: The combination of high b-value DWI with a FROC model is effective in distinguishing between NMIBC and MIBC, as well as in grading bladder tumors.
EUROPEAN RADIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Senay Yilmaz, Nilgun Yilmaz Demirci, Selma Metintas, Adil Zamani, Mehmet Karadag, Ozge A. Guclu, Pinar Akin Kabalak, Ulku Yilmaz, Guntulu Ak, Derya Kizilgoz, Akin Ozturk, Ufuk Yilmaz, Ozgur Batum, Murat Kavas, Irem Serifoglu, Meftun Unsal, Berna E. Komurcuoglu, Tuba Inal Cengiz, Gaye Ulubay, Tugce S. Ozdemirel, Berna A. Ozyurek, Suna Kavurgaci, Dursun Alizoroglu, Pinar Celik, Yurdanur Erdogan, Erdal In, Asude Aksoy, Sedat Altin, Gulsah Gunluoglu, Muzaffer Metintas
Summary: The study found that in asbestos-exposed non-smokers, the rates of EGFR mutations and ALK rearrangements were higher. EGFR mutation was associated with female gender and non-smoking, while ALK rearrangement was associated with younger age, non-smoking, and a history of asbestos exposure.
JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2021)
Article
Surgery
Efsun Gonca Ugur Chousein, Demet Turan, Mehmet Akif Ozgul, Erdogan Cetinkaya
Summary: Interventional bronchoscopic procedures show good outcomes for patients with secondary pulmonary malignancies, significantly alleviating symptoms and improving survival rates. Laser application, in particular, demonstrates a significant effect on enhancing survival rates.
TURK GOGUS KALP DAMAR CERRAHISI DERGISI-TURKISH JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2021)
Article
Respiratory System
Efsun G. Ugur Chousein, Demet Turan, Elif Tanriverdi, Binnaz Yildirim, Mustafa Cortuk, Halit Cinarka, Mehmet A. Ozgul, Erdogan Cetinkaya
Summary: ACC mainly affects central airways, particularly the trachea. IBPs can be repeatedly used in the treatment of ACC due to low early complication rates. Patients treated with airway stents should be closely monitored for late complications.
Article
Medicine, General & Internal
Onur Turan, Nilgun Yilmaz Demirci, Guntulu Ak, Sule Akcay, Ulku Aka Akturk, Semra Bilaceroglu, Funda Coskun, Oguz Kokturk, Arzu Mirici, Cengiz Ozdemir, Nazan Sen, Ulku Yilmaz
Summary: This study investigated the mental health of healthcare workers during the COVID-19 outbreak in Turkey. The results showed that 44.6% of participants experienced anxiety and 68.2% experienced depression. Being younger than 50 and taking care of COVID-19 patients in hospitals were associated with a higher risk of anxiety. Female gender, young age (less than 50), and...
AFRICAN HEALTH SCIENCES
(2022)
Review
Respiratory System
Cemal Bes, Erdogan Cetinkaya
Summary: Systemic sclerosis (SSc) is a connective tissue disease characterized by immune irregularity, vasculopathy, and excessive collagen production, leading to fibrosis of skin and internal organs. Lung involvement, particularly interstitial lung disease (ILD), is the leading cause of death in SSc. The emergence of different treatment options in recent years has brought hope to clinicians in managing this disease.
TUBERKULOZ VE TORAKS-TUBERCULOSIS AND THORAX
(2022)
Article
Respiratory System
Guntulu Ak, Selma Metintas, Ayse Naz Taskin, Melahat Uzel Sener, Yasemin Soyler, Meltem Yilmaz, Akif Turna, Pinar Akin Kabalak, Semra Bilaceroglu, Deniz Koksal, Nilgun Yilmaz Demirci, Ozlem Sogukpinar, Sibel Boga, Merve Ercelik, Gulistan Karadeniz, Gulru Polat, Filiz Guldaval, Ulku Aka Akturk, Senay Yilmaz, Nalan Ogan, Saliha Yilmaz, Dorina Esendagli, Benan Caglayan, Arife Zeybek, Nagihan Durmus Kocak, Pinar Mutlu, Cansel Atinkaya Baytemir, Ismail Sarbay, Ulku Yilmaz, Muzaffer Metintas
Summary: The aim of this study was to evaluate the diagnostic performance of pleural procedures in undiagnosed exudative pleural effusions and identify factors suggestive of benign or malignant effusions. The study found that combining cytology with image-guided pleural biopsy significantly improved diagnostic sensitivity.
Article
Respiratory System
Fatma Merve Tepetam, Ravza Bayraktar, Erdogan Cetinkaya, Elif Tanriverdi, Baris Demirkol
Summary: Glucocorticoids are the main treatment for sarcoidosis, but some patients are resistant or have side effects. Infliximab, a monoclonal antibody, plays a critical role in the inflammation. This study presents a patient who improved with infliximab treatment due to side effects of corticosteroids, but experienced an early hypersensitivity reaction after relapse.
TUBERKULOZ VE TORAKS-TUBERCULOSIS AND THORAX
(2022)
Article
Respiratory System
Aykut Cilli, Nesrin Ocal, Fatih Uzer, Funda Coskun, Can Sevinc, Ahmet Ursavas, Pinar Yildiz, Pelin Pinar Deniz, Nilgun Yilmaz Demirci, Gamze Ozbey, Ahmet Yurttas, Ismail Hanta
Summary: This study examined the tolerability and safety of antifibrotics in elderly patients with IPF and found that elderly patients experienced significantly increased adverse events and dose reductions compared to non-elderly patients. Additionally, elderly patients had higher disease severity, hospitalization rates, exacerbation rates, and mortality rates.
RESPIRATORY INVESTIGATION
(2023)
Article
Respiratory System
Yesim Yildiz, Burcu Ozturk Sahin, Mert Can Tasdemir, Serife Demir, Beyza Cifci, Nurdan Kokturk, Tansu Ulukavak Ciftci, Ahmet Selim Yurdakul, Nilguen Yilmaz Demirci, Muege Aydogdu, Murat Dizbay, Ipek Kivilcim Oguzulgen
Summary: This study investigates the symptoms and risk factors of post-acute sequelae of COVID-19 in survivors. The prevalence of persistent symptoms was found to be 24.3%, with dyspnea, fatigue, arthralgia-myalgia, cough, and back pain being the most common sequelae. Having lung diseases, a history of intensive care support, the requirement for long-term oxygen therapy, and a history of cytokine storm were identified as risk factors for the persistence of dyspnea.
TUBERKULOZ VE TORAKS-TUBERCULOSIS AND THORAX
(2023)
Article
Medicine, General & Internal
Esra Ertan Yazar, Burcu Arpinar Yigitbas, Can Ozturk, Mukadder Calikoglu, Gazi Gulbas, Muzaffer Onur Turan, Hulya Sahin, Nurhan Sarioglu, Nevin Taci Hoca, Fulsen Bozkus, Seda Tural Onur, Nihal Arzu Mirici, Nalan Ogan, Nilgun Yilmaz Demirci, Burcu Yormaz, Ayperi Ozturk, Filiz Kosar, Evrim Eylem Akpinar, Gulsah Gunluoglu, Burak Mete, Mecit Suerdem
Summary: This study investigated the distribution, characteristics, and treatment preference of COPD phenotypes in Turkey. The results showed that some COPD patients had two or more phenotypes, and identifying the phenotypic traits may enable more effective and individualized treatment.
TURKISH JOURNAL OF MEDICAL SCIENCES
(2022)
Meeting Abstract
Respiratory System
Muzaffer Onur Turan, Nilgun Yilmaz Demirci, Guntulu Ak, Sule Akcay, Ulku Aka Akturk, Semra Bilaceroglu, Funda Coskun, Oguz Kokturk, Arzu Mirici, Ozdemi. R. Cengiz, Nazan Sen, Ulku Yilmaz
EUROPEAN RESPIRATORY JOURNAL
(2021)
Meeting Abstract
Respiratory System
Nilgun Yilmaz Demirci, Asiye Ugras Dikmen, Canturk Tasci, Deniz Dogan, Yakup Arslan, Nesrin Ocal, Mustafa Tasar, Ugur Bozlar, Cumhur Artuk, Gulden Gulden, Zehra Karacaer, Ismail Yasar Avci, Gunay Tuncer Ertem, Fatma Sebnem Erdinc, Sami Kinikli, Serife Altun Demircan, Elif Ergun, Pinar Nercis Kosar, Ayse Esra Karakoc, Atila Gokcek, Melike Aloglu, Sevtap Gulgosteren, Sukran Atikcan, Sule Akcay, Cigdem Erol, Koray Hekimoglu, Mahi Nur Cerit, Gonca Erbas, Selcuk Ozger, Gulendam Bozdayi, Esin Senol, Ahmet Selim Yurdakul, Aydin Yilmaz
EUROPEAN RESPIRATORY JOURNAL
(2021)
Article
Pharmacology & Pharmacy
Semih Bulut, Burcu Ozturk Sahin, Nilgun Yilmaz Demirci, Didem Deliorman Orhan
Summary: The study found that during the COVID-19 pandemic, approximately 32% of patients used herbal products, primarily to boost their immune systems. Most participants first consulted spice sellers about the use of medicinal plants against COVID-19, indicating a widespread demand for herbal products in society.
JOURNAL OF RESEARCH IN PHARMACY
(2021)
Article
Respiratory System
Tarkan Ozdemir, Hatice Kilic, Nilgun Yilmaz Demirci, Cigdem Ozdilekcan, Guven Bektemur, Mustafa Hamidullah Turkkani, Simten Malhan, H. Canan Hasanoglu, Orhan Koc, Can Ozturk
Summary: The study revealed that the direct costs of COPD patients treated in different healthcare centers increased by 41% between 2012 and 2016, with a total direct cost of 1003TL per patient in 2016. In 2016, the average number and cost of specialist consultations per patient were 1.7 visits and 42TL, while the average number and cost of emergency visits per patient were 0.4 visits and 71TL. For the inpatient group, the mean number of hospitalizations per patient, mean number of hospitalization days, and mean cost per hospitalization were 0.4 visits, 6.5 days, and 1926TL, respectively.
TURKISH THORACIC JOURNAL
(2021)
Article
Medicine, General & Internal
Elif Tanriverdi, Mustafa Cortuk, Binnaz Zeynep Yildirim, Efsun Gonca Ugur Chousein, Demet Turan, Halit Cinarka, Mehmet Akif Ozgul, Erdogan Cetinkaya
Summary: The study evaluated 83 patients with COVID-19 pneumonia and found that older age and more comorbidities were associated with poorer outcomes; in patients receiving azithromycin plus hydroxychloroquine and other antibiotics plus hydroxychloroquine, the duration of hospitalization was shorter in the azithromycin group. Early treatment and admission to hospital may be crucial for better treatment outcomes.
TURKISH JOURNAL OF MEDICAL SCIENCES
(2021)
