Neutralization of Zika virus by germline-like human monoclonal antibodies targeting cryptic epitopes on envelope domain III

Zika Virus Vaccines — A Full Field and Looking for the Closers

(2017) Stephen J. Thomas   NEW ENGLAND JOURNAL OF MEDICINE

A peptide-based viral inactivator inhibits Zika virus infection in pregnant mice and fetuses

(2017) Yufeng Yu et al.   Nature Communications

Visual and Motor Deficits in Grown-up Mice with Congenital Zika Virus Infection

(2017) Liyuan Cui et al.   EBioMedicine

The development of therapeutic antibodies against dengue virus

(2016) Guntur Fibriansah et al.   ANTIVIRAL RESEARCH

Structural Basis of Zika Virus-Specific Antibody Protection

(2016) Haiyan Zhao et al.   CELL

Structures of the Zika Virus Envelope Protein and Its Complex with a Flavivirus Broadly Protective Antibody

(2016) Lianpan Dai et al.   Cell Host & Microbe

A Mouse Model of Zika Virus Pathogenesis

(2016) Helen M. Lazear et al.   Cell Host & Microbe

The Emerging Zika Virus Epidemic in the Americas

(2016) Helen M. Lazear et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Zika Virus: New Clinical Syndromes and Its Emergence in the Western Hemisphere

(2016) Helen M. Lazear et al.   JOURNAL OF VIROLOGY

Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study

(2016) Van-Mai Cao-Lormeau et al.   LANCET

Differential killing of CD56-expressing cells by drug-conjugated human antibodies targeting membrane-distal and membrane-proximal non-overlapping epitopes

(2016) Yang Feng et al.   mAbs

Structural diversity in a human antibody germline library

(2016) Alexey Teplyakov et al.   mAbs

Structural basis of potent Zika–dengue virus antibody cross-neutralization

(2016) Giovanna Barba-Spaeth et al.   NATURE

Vaccine protection against Zika virus from Brazil

(2016) Rafael A. Larocca et al.   NATURE

Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice

(2016) Gopal Sapparapu et al.   NATURE

Dengue virus sero-cross-reactivity drives antibody-dependent enhancement of infection with zika virus

(2016) Wanwisa Dejnirattisai et al.   NATURE IMMUNOLOGY

Considerations for Developing a Zika Virus Vaccine

(2016) Hilary D. Marston et al.   NEW ENGLAND JOURNAL OF MEDICINE

Zika Virus Associated with Microcephaly

(2016) Jernej Mlakar et al.   NEW ENGLAND JOURNAL OF MEDICINE

Human antibody responses after dengue virus infection are highly cross-reactive to Zika virus

(2016) Lalita Priyamvada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diagnostics for Zika virus on the horizon

(2016) S. D. Speer et al.   SCIENCE

The 3.8 A resolution cryo-EM structure of Zika virus

(2016) D. Sirohi et al.   SCIENCE

Isolation, identification and genomic characterization of the Asian lineage Zika virus imported to China

(2016) Yong-Qiang Deng et al.   Science China-Life Sciences

Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus

(2016) Q. Wang et al.   Science Translational Medicine

Potent neutralizing monoclonal antibodies against Ebola virus infection

(2016) Qi Zhang et al.   Scientific Reports

Passive Transfer of A Germline-like Neutralizing Human Monoclonal Antibody Protects Transgenic Mice Against Lethal Middle East Respiratory Syndrome Coronavirus Infection

(2016) Anurodh Shankar Agrawal et al.   Scientific Reports

Characterization of Lethal Zika Virus Infection in AG129 Mice

(2016) Matthew T. Aliota et al.   PLoS Neglected Tropical Diseases

Flavivirus NS1 protein in infected host sera enhances viral acquisition by mosquitoes

(2016) Jianying Liu et al.   Nature Microbiology

Pharmacodynamics of long-acting folic acid-receptor targeted ritonavir-boosted atazanavir nanoformulations

(2015) Pavan Puligujja et al.   BIOMATERIALS

Broad and strong: the ultimate antibody to dengue virus

(2015) Josefina Coloma et al.   NATURE IMMUNOLOGY

A New Quaternary Structure Epitope on Dengue Virus Serotype 2 Is the Target of Durable Type-Specific Neutralizing Antibodies

(2015) E. N. Gallichotte et al.   mBio

Junctional and allele-specific residues are critical for MERS-CoV neutralization by an exceptionally potent germline-like antibody

(2015) Tianlei Ying et al.   Nature Communications

Dengue E Protein Domain III-Based DNA Immunisation Induces Strong Antibody Responses to All Four Viral Serotypes

(2015) Monica Poggianella et al.   PLoS Neglected Tropical Diseases

Exceptionally Potent Neutralization of Middle East Respiratory Syndrome Coronavirus by Human Monoclonal Antibodies

(2014) Tianlei Ying et al.   JOURNAL OF VIROLOGY

A new class of highly potent, broadly neutralizing antibodies isolated from viremic patients infected with dengue virus

(2014) Wanwisa Dejnirattisai et al.   NATURE IMMUNOLOGY

Dengue virus envelope domain III immunization elicits predominantly cross-reactive, poorly neutralizing antibodies localized to the AB loop: implications for dengue vaccine design

(2013) X.-Q. Li et al.   JOURNAL OF GENERAL VIROLOGY

High-Avidity and Potently Neutralizing Cross-Reactive Human Monoclonal Antibodies Derived from Secondary Dengue Virus Infection

(2013) Wen-Yang Tsai et al.   JOURNAL OF VIROLOGY

Dissection of Antibody Specificities Induced by Yellow Fever Vaccination

(2013) Oksana Vratskikh et al.   PLoS Pathogens

Identification of human neutralizing antibodies that bind to complex epitopes on dengue virions

(2012) R. de Alwis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis of Differential Neutralization of DENV-1 Genotypes by an Antibody that Recognizes a Cryptic Epitope

(2012) S. Kyle Austin et al.   PLoS Pathogens

A Dynamic Landscape for Antibody Binding Modulates Antibody-Mediated Neutralization of West Nile Virus

(2011) Kimberly A. Dowd et al.   PLoS Pathogens

The Human Immune Response to Dengue Virus Is Dominated by Highly Cross-Reactive Antibodies Endowed with Neutralizing and Enhancing Activity

(2010) Martina Beltramello et al.   Cell Host & Microbe

Therapeutic antibodies, vaccines and antibodyomes

(2010) Dimiter S. Dimitrov   mAbs

The Development of Therapeutic Antibodies That Neutralize Homologous and Heterologous Genotypes of Dengue Virus Type 1

(2010) Bimmi Shrestha et al.   PLoS Pathogens

Zika Virus Outbreak on Yap Island, Federated States of Micronesia

(2009) Mark R. Duffy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dengue virus neutralization by human immune sera: Role of envelope protein domain III-reactive antibody

(2009) W.M.P.B. Wahala et al.   VIROLOGY

Structural Insights into the Mechanisms of Antibody-Mediated Neutralization of Flavivirus Infection: Implications for Vaccine Development

(2008) Theodore C. Pierson et al.   Cell Host & Microbe

Antibodies to Envelope Glycoprotein of Dengue Virus during the Natural Course of Infection Are Predominantly Cross-Reactive and Recognize Epitopes Containing Highly Conserved Residues at the Fusion Loop of Domain II

(2008) C.-Y. Lai et al.   JOURNAL OF VIROLOGY

Structure of the Immature Dengue Virus at Low pH Primes Proteolytic Maturation

(2008) I-M. Yu et al.   SCIENCE