Genome-Wide Association Meta-Analysis Reveals Novel Juvenile Idiopathic Arthritis Susceptibility Loci

A combined large-scale meta-analysis identifiesCOG6as a novel shared risklocusfor rheumatoid arthritis and systemic lupus erythematosus

(2016) Ana Márquez et al.   ANNALS OF THE RHEUMATIC DISEASES

Fine-mapping the MHC locus in juvenile idiopathic arthritis (JIA) reveals genetic heterogeneity corresponding to distinct adult inflammatory arthritic diseases

(2016) A Hinks et al.   ANNALS OF THE RHEUMATIC DISEASES

A Synonymous Variant in IL10RA Affects RNA Splicing in Paediatric Patients with Refractory Inflammatory Bowel Disease

(2016) Seak Hee Oh et al.   Journal of Crohns & Colitis

Single synonymous mutation in factor IX alters protein properties and underlies haemophilia B

(2016) Vijaya L Simhadri et al.   JOURNAL OF MEDICAL GENETICS

A Case of IL-7R Deficiency Caused by a Novel Synonymous Mutation and Implications for Mutation Screening in SCID Diagnosis

(2016) Fernando Gallego-Bustos et al.   Frontiers in Immunology

Recent progress and perspective in JAK inhibitors for rheumatoid arthritis: from bench to bedside

(2015) Yoshiya Tanaka   JOURNAL OF BIOCHEMISTRY

Association analysis of GWAS and candidate gene loci in a Pakistani population with psoriasis

(2015) Saeeda Munir et al.   MOLECULAR IMMUNOLOGY

Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers

(2015) Suna Onengut-Gumuscu et al.   NATURE GENETICS

Capture Hi-C reveals novel candidate genes and complex long-range interactions with related autoimmune risk loci

(2015) Paul Martin et al.   Nature Communications

Transcriptional enhancers: from properties to genome-wide predictions

(2014) Daria Shlyueva et al.   NATURE REVIEWS GENETICS

Advances in CTLA-4-Ig-mediated modulation of inflammatory cell and immune response activation in rheumatoid arthritis

(2013) Maurizio Cutolo et al.   AUTOIMMUNITY REVIEWS

Genetics of rheumatoid arthritis contributes to biology and drug discovery

(2013) Yukinori Okada et al.   NATURE

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

(2013) Ashley H Beecham et al.   NATURE GENETICS

Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis

(2013) Anne Hinks et al.   NATURE GENETICS

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Systematic identification of trans eQTLs as putative drivers of known disease associations

(2013) Harm-Jan Westra et al.   NATURE GENETICS

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

(2013) Danielle Welter et al.   NUCLEIC ACIDS RESEARCH

Meta-analysis Followed by Replication Identifies Loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as Associated with Systemic Lupus Erythematosus in Asians

(2012) Wanling Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13

(2012) Susan D. Thompson et al.   ARTHRITIS AND RHEUMATISM

An intronic variant associated with systemic lupus erythematosus changes the binding affinity of Yinyang1 to downregulate WDFY4

(2012) H Zhao et al.   GENES AND IMMUNITY

Annotation of functional variation in personal genomes using RegulomeDB

(2012) A. P. Boyle et al.   GENOME RESEARCH

Seven newly identified loci for autoimmune thyroid disease

(2012) Jason D. Cooper et al.   HUMAN MOLECULAR GENETICS

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

(2011) Gosia Trynka et al.   NATURE GENETICS

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

(2011) L. D. Ward et al.   NUCLEIC ACIDS RESEARCH

A functional RANKL polymorphism associated with younger age at onset of rheumatoid arthritis

(2010) Wenfeng Tan et al.   ARTHRITIS AND RHEUMATISM

Quantification of the familial contribution to juvenile idiopathic arthritis

(2010) Sampath Prahalad et al.   ARTHRITIS AND RHEUMATISM

The susceptibility loci juvenile idiopathic arthritis shares with other autoimmune diseases extend to PTPN2, COG6, and ANGPT1

(2010) Susan D. Thompson et al.   ARTHRITIS AND RHEUMATISM

Juvenile idiopathic arthritis and HLA Class I and Class II interactions and age-at-onset effects

(2010) Jill A. Hollenbach et al.   ARTHRITIS AND RHEUMATISM

Robust relationship inference in genome-wide association studies

(2010) Ani Manichaikul et al.   BIOINFORMATICS

Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus

(2010) Wanling Yang et al.   PLoS Genetics

Identification of a novel susceptibility locus for juvenile idiopathic arthritis by genome-wide association analysis

(2009) Anne Hinks et al.   ARTHRITIS AND RHEUMATISM

Fast model-based estimation of ancestry in unrelated individuals

(2009) D. H. Alexander et al.   GENOME RESEARCH

B7-1/2 (CD80/CD86) Direct Signaling to B Cells Enhances IgG Secretion

(2009) F. C. Rau et al.   JOURNAL OF IMMUNOLOGY

Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus

(2009) Jian-Wen Han et al.   NATURE GENETICS

CTLA4-Ig interacts with cultured synovial macrophages from rheumatoid arthritis patients and downregulates cytokine production

(2009) Maurizio Cutolo et al.   ARTHRITIS RESEARCH & THERAPY

Association of the TRAF1–C5 locus on chromosome 9 with juvenile idiopathic arthritis

(2008) Edward M. Behrens et al.   ARTHRITIS AND RHEUMATISM

Role of the conserved oligomeric Golgi (COG) complex in protein glycosylation

(2008) Richard D. Smith et al.   CARBOHYDRATE RESEARCH

Association of Skin Barrier Genes within the PSORS4 Locus Is Enriched in Singaporean Chinese with Early-Onset Psoriasis

(2008) Huijia Chen et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY