Population-Specific Resequencing Associates the ATP-Binding Cassette Subfamily C Member 4 Gene With Gout in New Zealand Māori and Pacific Men

Polymorphic variants of MRP4/ABCC4 differentially modulate the transport of methylated arsenic metabolites and physiological organic anions

(2016) Mayukh Banerjee et al.   BIOCHEMICAL PHARMACOLOGY

Gout

(2016) Nicola Dalbeth et al.   LANCET

Analysis of protein-coding genetic variation in 60,706 humans

(2016) Monkol Lek et al.   NATURE

The Molecular Physiology of Uric Acid Homeostasis

(2015) Asim K. Mandal et al.   Annual Review of Physiology

Twenty-eight loci that influence serum urate levels: analysis of association with gout

(2014) A J Phipps-Green et al.   ANNALS OF THE RHEUMATIC DISEASES

A general framework for estimating the relative pathogenicity of human genetic variants

(2014) Martin Kircher et al.   NATURE GENETICS

Emerging Therapies for Gout

(2014) N. Lawrence Edwards et al.   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

The Genetic Basis of Gout

(2014) Tony R. Merriman et al.   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

Population-specific influence ofSLC2A9genotype on the acute hyperuricaemic response to a fructose load

(2013) Nicola Dalbeth et al.   ANNALS OF THE RHEUMATIC DISEASES

Gout-causing Q141K mutation in ABCG2 leads to instability of the nucleotide-binding domain and can be corrected with small molecules

(2013) O. M. Woodward et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hyperuricaemia in the Pacific: why the elevated serum urate levels?

(2013) Anna L. Gosling et al.   RHEUMATOLOGY INTERNATIONAL

GEMINI: Integrative Exploration of Genetic Variation and Genome Annotations

(2013) Umadevi Paila et al.   PLoS Computational Biology

Systematic review of the prevalence of gout and hyperuricaemia in Australia

(2012) P. C. Robinson et al.   INTERNAL MEDICINE JOURNAL

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

(2012) Anna Köttgen et al.   NATURE GENETICS

National prevalence of gout derived from administrative health data in Aotearoa New Zealand

(2012) D. Winnard et al.   RHEUMATOLOGY

A framework for variation discovery and genotyping using next-generation DNA sequencing data

(2011) Mark A DePristo et al.   NATURE GENETICS

Population Heterogeneity in the Genetic Control of Serum Urate

(2011) Tony R. Merriman   SEMINARS IN NEPHROLOGY

Renal Secretion of Uric Acid by Organic Anion Transporter 2 (OAT2/SLC22A7) in Human

(2010) Masanobu Sato et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

A strong role for the ABCG2 gene in susceptibility to gout in New Zealand Pacific Island and Caucasian, but not Māori, case and control sample sets

(2010) Amanda J. Phipps-Green et al.   HUMAN MOLECULAR GENETICS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout

(2009) O. M. Woodward et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of hypouricaemic and hyperuricaemic drugs on the renal urate efflux transporter, multidrug resistance protein 4

(2008) A A K El-Sheikh et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Human Multidrug Resistance Protein 4 (MRP4, ABCC4): Functional Analysis of a Highly Polymorphic Gene

(2008) N. Abla et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study

(2008) Abbas Dehghan et al.   LANCET