Rheumatoid Arthritis Naive T Cells Share Hypermethylation Sites With Synoviocytes

Sparse PCA corrects for cell type heterogeneity in epigenome-wide association studies

(2016) Elior Rahmani et al.   NATURE METHODS

Genome-wide profiling in treatment-naive early rheumatoid arthritis reveals DNA methylome changes in T and B lymphocytes

(2016) John R Glossop et al.   Epigenomics

Omics for prediction of environmental health effects: Blood leukocyte-based cross-omic profiling reliably predicts diseases associated with tobacco smoking

(2016) Panagiotis Georgiadis et al.   Scientific Reports

Power and sample size estimation for epigenome-wide association scans to detect differential DNA methylation

(2015) Pei-Chien Tsai et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

DNA methylation profiling of synovial fluid FLS in rheumatoid arthritis reveals changes common with tissue-derived FLS

(2015) John R Glossop et al.   Epigenomics

A DNA methylation-based definition of biologically distinct breast cancer subtypes

(2014) Olafur A. Stefansson et al.   Molecular Oncology

Epigenome-wide association studies without the need for cell-type composition

(2014) James Zou et al.   NATURE METHODS

Genetic and epigenetic predictors of responsiveness to treatment in RA

(2014) Darren Plant et al.   Nature Reviews Rheumatology

A weighted genetic risk score using all known susceptibility variants to estimate rheumatoid arthritis risk

(2013) Annie Yarwood et al.   ANNALS OF THE RHEUMATIC DISEASES

Considerations for normalization of DNA methylation data by Illumina 450K BeadChip assay in population studies

(2013) Paul Yousefi et al.   Epigenetics

Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray

(2013) Yi-an Chen et al.   Epigenetics

Development and Maintenance of Regulatory T cells

(2013) Naganari Ohkura et al.   IMMUNITY

Phosphofructokinase deficiency impairs ATP generation, autophagy, and redox balance in rheumatoid arthritis T cells

(2013) Zhen Yang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genetics of rheumatoid arthritis contributes to biology and drug discovery

(2013) Yukinori Okada et al.   NATURE

Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis

(2013) Yun Liu et al.   NATURE BIOTECHNOLOGY

Genetic insights into common pathways and complex relationships among immune-mediated diseases

(2013) Miles Parkes et al.   NATURE REVIEWS GENETICS

An imprinted rheumatoid arthritis methylome signature reflects pathogenic phenotype

(2013) John W Whitaker et al.   Genome Medicine

A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data

(2012) Andrew E. Teschendorff et al.   BIOINFORMATICS

High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis

(2012) Steve Eyre et al.   NATURE GENETICS

Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis

(2012) Soumya Raychaudhuri et al.   NATURE GENETICS

Differential DNA Methylation in Purified Human Blood Cells: Implications for Cell Lineage and Studies on Disease Susceptibility

(2012) Lovisa E. Reinius et al.   PLoS One

pROC: an open-source package for R and S+ to analyze and compare ROC curves

(2011) Xavier Robin et al.   BMC BIOINFORMATICS

Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome

(2011) Juan Sandoval et al.   Epigenetics

High density DNA methylation array with single CpG site resolution

(2011) Marina Bibikova et al.   GENOMICS

Racial and ethnic disparities in disease activity and function among persons with rheumatoid arthritis from university-affiliated clinics

(2011) J. L. Barton et al.   ARTHRITIS CARE & RESEARCH

Smoking is a major preventable risk factor for rheumatoid arthritis: estimations of risks after various exposures to cigarette smoke

(2010) H. Kallberg et al.   ANNALS OF THE RHEUMATIC DISEASES

The rheumatoid arthritis HLA–DRB1 shared epitope

(2010) Joseph Holoshitz   CURRENT OPINION IN RHEUMATOLOGY

Global DNA methylation, DNMT1, and MBD2 in patients with rheumatoid arthritis

(2010) Ching-Ching Liu et al.   IMMUNOLOGY LETTERS

Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis

(2009) Beatrix Bartok et al.   IMMUNOLOGICAL REVIEWS

Deficiency of the DNA repair enzyme ATM in rheumatoid arthritis

(2009) Lan Shao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Telomerase insufficiency in rheumatoid arthritis

(2009) H. Fujii et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epidemiological studies in incidence, prevalence, mortality, and comorbidity of the rheumatic diseases

(2009) Sherine E Gabriel et al.   ARTHRITIS RESEARCH & THERAPY

Methylation status of a single CpG site in theIL6promoter is related toIL6messenger RNA levels and rheumatoid arthritis

(2008) Christoper J. Nile et al.   ARTHRITIS AND RHEUMATISM