4.3 Article

Cytoprotective effects of essential oil of Pinus halepensis L. against aspirin-induced toxicity in IEC-6 cells

Journal

ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY
Volume 123, Issue 5, Pages 364-370

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/13813455.2017.1347689

Keywords

IEC-6 cells; aspirin; oxidative damage; Pinus halepensis L; antioxidant enzymes

Ask authors/readers for more resources

Context: Essential oils from Pinus species have been reported to have various therapeutic properties. Objective: This study was undertaken to identify the chemical composition and cytoprotective effects of the essential oil of Pinus halepensis L. against aspirin-induced damage in cells in vitro. Material and methods: The cytoprotection of the oil against toxicity of aspirin on the small intestine epithelial cells IEC-6 was tested. Results: The obtained results have shown that 35 different compounds were identified. Aspirin induced a decrease in cell viability, and exhibited significant damage to their morphology and an increase in superoxide dismutase (SOD) and catalase (CAT) activities. However, the co-treatment of aspirin with the essential oil of Pinus induced a significant increase in cell viability and a decrease in SOD and CAT activities. Conclusion: Overall, these finding suggest that the essential oil of Pinus halepensis L. has potent cytoprotective effect against aspirin-induced toxicity in IEC-6 cells.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.3
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available