Combined assessment of DYRK1A, BDNF and homocysteine levels as diagnostic marker for Alzheimer’s disease

Homocysteine induces PUMA-mediated mitochondrial apoptosis in SH-SY5Y cells

(2016) Yumi Jang et al.   AMINO ACIDS

Homocysteine, B Vitamins, and Cognitive Impairment

(2016) A. David Smith et al.   Annual Review of Nutrition

Altered regulation of the Spry2/Dyrk1A/PP2A triad by homocysteine impairs neural progenitor cell proliferation

(2016) Luis G. Rabaneda et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Overexpression of Dyrk1A , a Down Syndrome Candidate, Decreases Excitability and Impairs Gamma Oscillations in the Prefrontal Cortex

(2016) Marcel Ruiz-Mejias et al.   JOURNAL OF NEUROSCIENCE

Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants

(2016) Ronald S Duman et al.   NATURE MEDICINE

Phosphorylation of β-Tubulin by the Down Syndrome Kinase, Minibrain/DYRK1a, Regulates Microtubule Dynamics and Dendrite Morphogenesis

(2016) Kassandra M. Ori-McKenney et al.   NEURON

Regularized Linear Discriminant Analysis of EEG Features in Dementia Patients

(2016) Emanuel Neto et al.   Frontiers in Aging Neuroscience

Truncation and Activation of Dual Specificity Tyrosine Phosphorylation-regulated Kinase 1A by Calpain I

(2015) Nana Jin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells

(2015) Bernard Khor et al.   eLife

Excitation/inhibition balance and learning are modified by Dyrk1a gene dosage

(2014) Benoit Souchet et al.   NEUROBIOLOGY OF DISEASE

Plasma DYRK1A as a novel risk factor for Alzheimer’s disease

(2014) N Janel et al.   Translational Psychiatry

A high-performance liquid chromatography assay for Dyrk1a, a Down syndrome-associated kinase

(2013) Linh C. Bui et al.   ANALYTICAL BIOCHEMISTRY

GSK3β, CREB, and BDNF in peripheral blood of patients with Alzheimer's disease and depression

(2013) Jan Pláteník et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Time-of-flight secondary ion mass spectrometry (TOF-SIMS) imaging reveals cholesterol overload in the cerebral cortex of Alzheimer disease patients

(2012) Adina N. Lazar et al.   ACTA NEUROPATHOLOGICA

Mice Deficient in Cystathionine Beta Synthase Display Increased Dyrk1A and SAHH Activities in Brain

(2012) Chris Planque et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

BDNF and DYRK1A Are Variable and Inversely Correlated in Lymphoblastoid Cell Lines from Down Syndrome Patients

(2012) Asma Tlili et al.   MOLECULAR NEUROBIOLOGY

Dyrk1A, a Serine/Threonine Kinase, is Involved in ERK and Akt Activation in the Brain of Hyperhomocysteinemic Mice

(2012) Sabiha Abekhoukh et al.   MOLECULAR NEUROBIOLOGY

DYRK1A: A master regulatory protein controlling brain growth

(2012) Fayçal Guedj et al.   NEUROBIOLOGY OF DISEASE

Platelet protein kinase C and brain-derived neurotrophic factor levels in borderline personality disorder patients

(2012) Harold W. Koenigsberg et al.   PSYCHIATRY RESEARCH

Serum homocysteine and dementia: Meta-analysis of eight cohort studies including 8669 participants

(2011) David S. Wald et al.   Alzheimers & Dementia

Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Reisa A. Sperling et al.   Alzheimers & Dementia

The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Guy M. McKhann et al.   Alzheimers & Dementia

The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Marilyn S. Albert et al.   Alzheimers & Dementia

p53 downregulates Down syndrome-associated DYRK1A through miR-1246

(2011) Yu Zhang et al.   EMBO REPORTS

REST RegulatesDYRK1ATranscription in a Negative Feedback Loop

(2011) Mei Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alzheimer's disease

(2011) Clive Ballard et al.   LANCET

Brain-Derived Neurotrophic Factor and Alzheimer’s Disease: Physiopathology and Beyond

(2011) Breno Satler Diniz et al.   NEUROMOLECULAR MEDICINE

Anti-Aβ Therapeutics in Alzheimer's Disease: The Need for a Paradigm Shift

(2011) Todd E. Golde et al.   NEURON

Associations of serum brain-derived neurotrophic factor with cognitive impairments and negative symptoms in schizophrenia

(2011) Tomihisa Niitsu et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Genetic association of the Phosphoinositide-3 kinase in schizophrenia and bipolar disorder and interaction with a BDNF gene polymorphism

(2011) Anthony Carrard et al.   Brain and Behavior

Engineering DYRK1A overdosage yields Down syndrome-characteristic cortical splicing aberrations

(2010) Debra Toiber et al.   NEUROBIOLOGY OF DISEASE

Effect of brain-derived neurotrophic factor Val66Met polymorphism and serum levels on the progression of mild cognitive impairment

(2010) Orestes Vicente Forlenza et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

Negative Feedback Inhibition of NFATc1 by DYRK1A Regulates Bone Homeostasis

(2009) Youngkyun Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calpain activation is required for homocysteine-mediated hepatic degradation of inhibitor Ikappa B alpha

(2009) Julien Hamelet et al.   MOLECULAR GENETICS AND METABOLISM

Midlife homocysteine and late-life dementia in women. A prospective population study

(2009) Dimitri E. Zylberstein et al.   NEUROBIOLOGY OF AGING

Green Tea Polyphenols Rescue of Brain Defects Induced by Overexpression of DYRK1A

(2009) Fayçal Guedj et al.   PLoS One

DYRK1A, a Novel Determinant of the Methionine-Homocysteine Cycle in Different Mouse Models Overexpressing this Down-Syndrome-Associated Kinase

(2009) Christophe Noll et al.   PLoS One

Effect of hyperhomocysteinemia on the protein kinase DYRK1A in liver of mice

(2008) Julien Hamelet et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

BDNF is a novel marker of cognitive function in ageing women: The DR’s EXTRA Study

(2008) Pirjo Komulainen et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

BDNF: A key regulator for protein synthesis-dependent LTP and long-term memory?

(2007) Yuan Lu et al.   NEUROBIOLOGY OF LEARNING AND MEMORY