Cerebral organoids reveal early cortical maldevelopment in schizophrenia—computational anatomy and genomics, role of FGFR1

Common developmental genome deprogramming in schizophrenia — Role of Integrative Nuclear FGFR1 Signaling (INFS)

(2017) S.T. Narla et al.   SCHIZOPHRENIA RESEARCH

Evidence-Based Theory for Integrated Genome Regulation of Ontogeny-An Unprecedented Role of Nuclear FGFR1 Signaling

(2016) Michal K. Stachowiak et al.   JOURNAL OF CELLULAR PHYSIOLOGY

T-Brain-1 - A Potential Master Regulator in Autism Spectrum Disorders

(2015) Hsiu-Chun Chuang et al.   Autism Research

FOXG1-Dependent Dysregulation of GABA/Glutamate Neuron Differentiation in Autism Spectrum Disorders

(2015) Jessica Mariani et al.   CELL

Multikinase activity of fibroblast growth factor receptor (FGFR) inhibitors SU5402, PD173074, AZD1480, AZD4547 and BGJ398 compromises the use of small chemicals targeting FGFR catalytic activity for therapy of short-stature syndromes

(2015) Iva Gudernova et al.   HUMAN MOLECULAR GENETICS

“Nuclear FGF Receptor-1 and CREB Binding Protein: An Integrative Signaling Module”

(2015) Michal K. Stachowiak et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Global Developmental Gene Programing Involves a Nuclear Form of Fibroblast Growth Factor Receptor-1 (FGFR1)

(2015) Christopher Terranova et al.   PLoS One

Calretinin and parvalbumin in schizophrenia and affective disorders: a mini-review, a perspective on the evolutionary role of calretinin in schizophrenia, and a preliminary post-mortem study of calretinin in the septal nuclei

(2015) Ralf Brisch et al.   Frontiers in Cellular Neuroscience

Modeling a Genetic Risk for Schizophrenia in iPSCs and Mice Reveals Neural Stem Cell Deficits Associated with Adherens Junctions and Polarity

(2014) Ki-Jun Yoon et al.   Cell Stem Cell

Nuclear translocation of FGFR1 and FGF2 in pancreatic stellate cells facilitates pancreatic cancer cell invasion

(2014) S. J. Coleman et al.   EMBO Molecular Medicine

Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia

(2014) K Brennand et al.   MOLECULAR PSYCHIATRY

Synaptic dysregulation in a human iPS cell model of mental disorders

(2014) Zhexing Wen et al.   NATURE

Generation of cerebral organoids from human pluripotent stem cells

(2014) Madeline A Lancaster et al.   Nature Protocols

Three-dimensional organotypic culture: experimental models of mammalian biology and disease

(2014) Eliah R. Shamir et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Modeling Hippocampal Neurogenesis Using Human Pluripotent Stem Cells

(2014) Diana Xuan Yu et al.   Stem Cell Reports

Abnormal neuronal differentiation and mitochondrial dysfunction in hair follicle-derived induced pluripotent stem cells of schizophrenia patients

(2013) O Robicsek et al.   MOLECULAR PSYCHIATRY

Cerebral organoids model human brain development and microcephaly

(2013) Madeline A. Lancaster et al.   NATURE

NGF-Induced Cell Differentiation and Gene Activation Is Mediated by Integrative Nuclear FGFR1 Signaling (INFS)

(2013) Yu-Wei Lee et al.   PLoS One

Activation of Developmental Nuclear Fibroblast Growth Factor Receptor 1 Signaling and Neurogenesis in Adult Brain by α7 Nicotinic Receptor Agonist

(2013) Sridhar T. Narla et al.   Stem Cells Translational Medicine

Cooperation of Nuclear Fibroblast Growth Factor Receptor 1 and Nurr1 Offers New Interactive Mechanism in Postmitotic Development of Mesencephalic Dopaminergic Neurons

(2012) Olga Baron et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fibroblast Growth Factor (FGF) Signaling during Gastrulation Negatively Modulates the Abundance of MicroRNAs That Regulate Proteins Required for Cell Migration and Embryo Patterning

(2012) Alexander S. Bobbs et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel nuclear FGF Receptor-1 partnership with retinoid and Nur receptors during developmental gene programming of embryonic stem cells

(2012) Yu-Wei Lee et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Viral infection, inflammation and schizophrenia

(2012) Rachel E. Kneeland et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Schizophrenia: A neurodevelopmental disorder — Integrative genomic hypothesis and therapeutic implications from a transgenic mouse model

(2012) M.K. Stachowiak et al.   SCHIZOPHRENIA RESEARCH

FGF/MAPK signaling is required in the gastrula epiblast for avian neural crest induction

(2011) T. J. Stuhlmiller et al.   DEVELOPMENT

Modelling schizophrenia using human induced pluripotent stem cells

(2011) Kristen J. Brennand et al.   NATURE

Prediction of longitudinal functional outcomes in schizophrenia: The impact of baseline motivational deficits

(2011) G. Foussias et al.   SCHIZOPHRENIA RESEARCH

Toward the Next Generation of Negative Symptom Assessments: The Collaboration to Advance Negative Symptom Assessment in Schizophrenia

(2010) J. J. Blanchard et al.   SCHIZOPHRENIA BULLETIN

Calretinin immunoreactivity in focal cortical dysplasias and in non-malformed epileptic cortex

(2009) Filip Barinka et al.   EPILEPSY RESEARCH

Targeting novel integrative nuclear FGFR1 signaling by nanoparticle-mediated gene transfer stimulates neurogenesis in the adult brain

(2009) Ewa K. Stachowiak et al.   Integrative Biology

The Neurodevelopmental Hypothesis of Schizophrenia, Revisited

(2009) S. H. Fatemi et al.   SCHIZOPHRENIA BULLETIN

Segmental patterning of the vertebrate embryonic axis

(2008) Mary-Lee Dequéant et al.   NATURE REVIEWS GENETICS