Soluble Tau has devastating effects on the structural plasticity of hippocampal granule neurons

Amplifying mitochondrial function rescues adult neurogenesis in a mouse model of Alzheimer's disease

(2017) Kevin Richetin et al.   NEUROBIOLOGY OF DISEASE

GSK-3β Overexpression Alters the Dendritic Spines of Developmentally Generated Granule Neurons in the Mouse Hippocampal Dentate Gyrus

(2017) Noemí Pallas-Bazarra et al.   Frontiers in Neuroanatomy

Tau Aggregates: Toxic, Inert, or Protective Species?

(2017) Alexis Bretteville et al.   JOURNAL OF ALZHEIMERS DISEASE

Molecular mechanism of prion-like tau-induced neurodegeneration

(2016) Alejandra D. Alonso et al.   Alzheimers & Dementia

Novel function of Tau in regulating the effects of external stimuli on adult hippocampal neurogenesis

(2016) Noemí Pallas‐Bazarra et al.   EMBO JOURNAL

The Tau/A152T mutation, a risk factor for frontotemporal‐spectrum disorders, leads to NR2B receptor‐mediated excitotoxicity

(2016) Jochen Martin Decker et al.   EMBO REPORTS

Running rewires the neuronal network of adult-born dentate granule cells

(2016) Carmen Vivar et al.   NEUROIMAGE

Alzheimer's Disease and Hippocampal Adult Neurogenesis; Exploring Shared Mechanisms

(2016) Carolyn Hollands et al.   Frontiers in Neuroscience

Tau Trimers Are the Minimal Propagation Unit Spontaneously Internalized to Seed Intracellular Aggregation

(2015) Hilda Mirbaha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer’s disease brain

(2015) Shuko Takeda et al.   Nature Communications

Temporal dynamics of hippocampal neurogenesis in chronic neurodegeneration

(2014) Diego Gomez-Nicola et al.   BRAIN

Activity-Dependent Tau Protein Translocation to Excitatory Synapse Is Disrupted by Exposure to Amyloid-Beta Oligomers

(2014) M. L. Frandemiche et al.   JOURNAL OF NEUROSCIENCE

Tau Propagation, Different Tau Phenotypes, and Prion-like Properties of Tau

(2014) Bradley T. Hyman   NEURON

Performance on a pattern separation task by Alzheimer’s patients shows possible links between disrupted dentate gyrus activity and apolipoprotein E ∈4 status and cerebrospinal fluid amyloid-β42 levels

(2014) Keith A Wesnes et al.   Alzheimers Research & Therapy

Peripherally triggered and GSK-3β-driven brain inflammation differentially skew adult hippocampal neurogenesis, behavioral pattern separation and microglial activation in response to ibuprofen

(2014) M Llorens-Martín et al.   Translational Psychiatry

Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer’s disease model

(2013) Manuela Polydoro et al.   ACTA NEUROPATHOLOGICA

Pattern separation and pattern completion in Alzheimer's disease: Evidence of rapid forgetting in amnestic mild cognitive impairment

(2013) Brandon A. Ally et al.   HIPPOCAMPUS

An analysis of entorhinal cortex projections to the dentate gyrus, hippocampus, and subiculum of the neonatal macaque monkey

(2013) David G. Amaral et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Tau Accumulation Activates the Unfolded Protein Response by Impairing Endoplasmic Reticulum-Associated Degradation

(2013) J. F. Abisambra et al.   JOURNAL OF NEUROSCIENCE

GSK-3β overexpression causes reversible alterations on postsynaptic densities and dendritic morphology of hippocampal granule neurons in vivo

(2013) M Llorens-Martín et al.   MOLECULAR PSYCHIATRY

Microtubule-associated protein tau is essential for long-term depression in the hippocampus

(2013) T. Kimura et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Retrograde monosynaptic tracing reveals the temporal evolution of inputs onto new neurons in the adult dentate gyrus and olfactory bulb

(2013) A. Deshpande et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Involvement of Cholinergic Neurons in the Spreading of Tau Pathology

(2013) Diana Simón et al.   Frontiers in Neurology

Young Dentate Granule Cells Mediate Pattern Separation, whereas Old Granule Cells Facilitate Pattern Completion

(2012) Toshiaki Nakashiba et al.   CELL

Unique Processing During a Period of High Excitation/Inhibition Balance in Adult-Born Neurons

(2012) Antonia Marín-Burgin et al.   SCIENCE

Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation

(2011) Amar Sahay et al.   NATURE

Resolving New Memories: A Critical Look at the Dentate Gyrus, Adult Neurogenesis, and Pattern Separation

(2011) James B. Aimone et al.   NEURON

GSK3β Is Involved in the Relief of Mitochondria Pausing in a Tau-Dependent Manner

(2011) María Llorens-Martín et al.   PLoS One

Mifepristone Prevents Stress-Induced Apoptosis in Newborn Neurons and Increases AMPA Receptor Expression in the Dentate Gyrus of C57/BL6 Mice

(2011) María Llorens-Martín et al.   PLoS One

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

(2010) Lars M. Ittner et al.   CELL

Quiescent and Active Hippocampal Neural Stem Cells with Distinct Morphologies Respond Selectively to Physiological and Pathological Stimuli and Aging

(2010) Sebastian Lugert et al.   Cell Stem Cell

Intra and Extracellular Protein Interactions with Tau

(2010) F. Hernandez et al.   Current Alzheimer Research

Synaptic degeneration in Alzheimer’s disease

(2009) Thomas Arendt   ACTA NEUROPATHOLOGICA

Characteristics and consequences of muscarinic receptor activation by tau protein

(2009) Alberto Gómez-Ramos et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Essential role of tau phosphorylation in adult hippocampal neurogenesis

(2009) Xiao-Ping Hong et al.   HIPPOCAMPUS

Neural Correlates of Novel Object and Novel Location Recognition Behavior in the Mouse Anterior Cingulate Cortex

(2009) Aldis P. Weible et al.   JOURNAL OF NEUROPHYSIOLOGY

Microtubule assembly, organization and dynamics in axons and dendrites

(2009) Cecilia Conde et al.   NATURE REVIEWS NEUROSCIENCE

Tau-knockout mice show reduced GSK3-induced hippocampal degeneration and learning deficits

(2009) Elena Gómez de Barreda et al.   NEUROBIOLOGY OF DISEASE

Tau phosphorylation: the therapeutic challenge for neurodegenerative disease

(2009) Diane P. Hanger et al.   TRENDS IN MOLECULAR MEDICINE

Extracellular tau promotes intracellular calcium increase through M1 and M3 muscarinic receptors in neuronal cells

(2008) A. Gómez-Ramos et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Neurons born in the adult dentate gyrus form functional synapses with target cells

(2008) Nicolas Toni et al.   NATURE NEUROSCIENCE

Automated Three-Dimensional Detection and Shape Classification of Dendritic Spines from Fluorescence Microscopy Images

(2008) Alfredo Rodriguez et al.   PLoS One

Differential Regulation of Dynein and Kinesin Motor Proteins by Tau

(2008) R. Dixit et al.   SCIENCE