Structure and Functions of Blood Vessels and Vascular Niches in Bone

MC4R-dependent suppression of appetite by bone-derived lipocalin 2

(2017) Ioanna Mosialou et al.   NATURE

Human type H vessels are a sensitive biomarker of bone mass

(2017) Liang Wang et al.   Cell Death & Disease

Regulation of Hematopoiesis and Osteogenesis by Blood Vessel–Derived Signals

(2016) Saravana K. Ramasamy et al.   Annual Review of Cell and Developmental Biology

Leptin Receptor Promotes Adipogenesis and Reduces Osteogenesis by Regulating Mesenchymal Stromal Cells in Adult Bone Marrow

(2016) Rui Yue et al.   Cell Stem Cell

Distinct bone marrow blood vessels differentially regulate haematopoiesis

(2016) Tomer Itkin et al.   NATURE

Hoxb5 marks long-term haematopoietic stem cells and reveals a homogenous perivascular niche

(2016) James Y. Chen et al.   NATURE

Angiocrine functions of organ-specific endothelial cells

(2016) Shahin Rafii et al.   NATURE

Age-dependent modulation of vascular niches for haematopoietic stem cells

(2016) Anjali P. Kusumbe et al.   NATURE

Regulation of monocyte cell fate by blood vessels mediated by Notch signalling

(2016) Jaba Gamrekelashvili et al.   Nature Communications

Blood flow controls bone vascular function and osteogenesis

(2016) Saravana K. Ramasamy et al.   Nature Communications

Gremlin 1 Identifies a Skeletal Stem Cell with Bone, Cartilage, and Reticular Stromal Potential

(2015) Daniel L. Worthley et al.   CELL

Deep imaging of bone marrow shows non-dividing stem cells are mainly perisinusoidal

(2015) Melih Acar et al.   NATURE

Regulation of tissue morphogenesis by endothelial cell-derived signals

(2015) Saravana K. Ramasamy et al.   TRENDS IN CELL BIOLOGY

Leptin-Receptor-Expressing Mesenchymal Stromal Cells Represent the Main Source of Bone Formed by Adult Bone Marrow

(2014) Bo O. Zhou et al.   Cell Stem Cell

Vasculature-Associated Cells Expressing Nestin in Developing Bones Encompass Early Cells in the Osteoblast and Endothelial Lineage

(2014) Noriaki Ono et al.   DEVELOPMENTAL CELL

Osterix Marks Distinct Waves of Primitive and Definitive Stromal Progenitors during Bone Marrow Development

(2014) Toshihide Mizoguchi et al.   DEVELOPMENTAL CELL

Direct measurement of local oxygen concentration in the bone marrow of live animals

(2014) Joel A. Spencer et al.   NATURE

The bone marrow niche for haematopoietic stem cells

(2014) Sean J. Morrison et al.   NATURE

Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone

(2014) Anjali P. Kusumbe et al.   NATURE

Endothelial Notch activity promotes angiogenesis and osteogenesis in bone

(2014) Saravana K. Ramasamy et al.   NATURE

A subset of chondrogenic cells provides early mesenchymal progenitors in growing bones

(2014) Noriaki Ono et al.   NATURE CELL BIOLOGY

Osteoporosis, Fractures, and Diabetes

(2014) Peter Jackuliak et al.   International Journal of Endocrinology

The Key Role of the Blood Supply to Bone

(2014) Massimo Marenzana et al.   Bone Research

Skeletal Blood Flow in Bone Repair and Maintenance

(2014) Ryan E. Tomlinson et al.   Bone Research

Maternal and Offspring Pools of Osteocalcin Influence Brain Development and Functions

(2013) Franck Oury et al.   CELL

This Niche Is a Maze; An Amazing Niche

(2013) Maher Hanoun et al.   Cell Stem Cell

Molecular Signatures of Tissue-Specific Microvascular Endothelial Cell Heterogeneity in Organ Maintenance and Regeneration

(2013) Daniel J. Nolan et al.   DEVELOPMENTAL CELL

CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance

(2013) Adam Greenbaum et al.   NATURE

Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches

(2013) Lei Ding et al.   NATURE

Arteriolar niches maintain haematopoietic stem cell quiescence

(2013) Yuya Kunisaki et al.   NATURE

Quantitative imaging of haematopoietic stem and progenitor cell localization and hypoxic status in the bone marrow microenvironment

(2013) César Nombela-Arrieta et al.   NATURE CELL BIOLOGY

The HIF Signaling Pathway in Osteoblasts Directly Modulates Erythropoiesis through the Production of EPO

(2012) Erinn B. Rankin et al.   CELL

Endothelial and perivascular cells maintain haematopoietic stem cells

(2012) Lei Ding et al.   NATURE

Vascular niche E-selectin regulates hematopoietic stem cell dormancy, self renewal and chemoresistance

(2012) Ingrid G Winkler et al.   NATURE MEDICINE

Basic and Therapeutic Aspects of Angiogenesis

(2011) Michael Potente et al.   CELL

Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche

(2011) Toshio Suda et al.   Cell Stem Cell

Molecular mechanisms and clinical applications of angiogenesis

(2011) Peter Carmeliet et al.   NATURE

Positioning of bone marrow hematopoietic and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells reside in distinct nonperfused niches

(2010) I. G. Winkler et al.   BLOOD

Insulin Signaling in Osteoblasts Integrates Bone Remodeling and Energy Metabolism

(2010) Mathieu Ferron et al.   CELL

Regulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells

(2010) Keiyo Takubo et al.   Cell Stem Cell

Osteoblast Precursors, but Not Mature Osteoblasts, Move into Developing and Fractured Bones along with Invading Blood Vessels

(2010) Christa Maes et al.   DEVELOPMENTAL CELL

Bone mineral loss and recovery after 17 weeks of bed rest

(2010) Adrian D. Leblanc et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Functional Heterogeneity of the Bone Marrow Vascular Niche

(2009) Hans-Georg Kopp et al.   Annals of the New York Academy of Sciences

Hematopoietic Stem Cell Development Is Dependent on Blood Flow

(2009) Trista E. North et al.   CELL

Engraftment and Reconstitution of Hematopoiesis Is Dependent on VEGFR2-Mediated Regeneration of Sinusoidal Endothelial Cells

(2009) Andrea T. Hooper et al.   Cell Stem Cell

Prevalence and Progression of Osteoporosis in Patients With COPD

(2009) Gary T. Ferguson et al.   CHEST

Regulation of Osteogenesis-Angiogenesis Coupling by HIFs and VEGF

(2009) Ernestina Schipani et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Lrp5 Controls Bone Formation by Inhibiting Serotonin Synthesis in the Duodenum

(2008) Vijay K. Yadav et al.   CELL

A Perivascular Origin for Mesenchymal Stem Cells in Multiple Human Organs

(2008) Mihaela Crisan et al.   Cell Stem Cell

Role of platelet-derived growth factors in physiology and medicine

(2008) J. Andrae et al.   GENES & DEVELOPMENT

Compromised Bone Marrow Perfusion in Osteoporosis

(2008) James F Griffith et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Endocrine functions of bone in mineral metabolism regulation

(2008) L. Darryl Quarles   JOURNAL OF CLINICAL INVESTIGATION

The bone marrow niche: habitat to hematopoietic and mesenchymal stem cells and unwitting host to molecular parasites

(2008) Y Shiozawa et al.   LEUKEMIA

Osteocalcin differentially regulates β cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice

(2008) Mathieu Ferron et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of the hypoxia-inducible factor-1  pathway accelerates bone regeneration

(2008) C. Wan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA