Journal
SAUDI JOURNAL OF BIOLOGICAL SCIENCES
Volume 25, Issue 7, Pages 1509-1513Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.sjbs.2017.08.005
Keywords
Total polyphenols; Onion; Antioxidant; Xanthine oxidase; Inhibitory activities
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Funding
- National Natural Science Foundation of China [31560192, 31100421]
- Natural Science Foundation of Hunan Province [1311B011]
- Science and Technology Project of the Key Laboratory for Ecotourism of Hunan Province [JSSTLY1516]
- JSPS Invitation Fellowships for Research in Japan of the Japan Society for the Promotion of Science [L15711]
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Onions (Allium cepa L.) comprise a valuable vegetable crop in many countries. Modern scientific research has shown that onions possess many biological activities, including antibacterial, anticancer, hypoglycemic, hypolipidemic, antiplatelet aggregation, and antioxidant activities. The goal of this study was to investigate the impact of total onion polyphenols on antioxidant and xanthine oxidase (XO) inhibitory activities. Total onion polyphenols showed significant antioxidant activity in DPPH, FRAP, and OH-assays (IC50 [mg/mL]), 43.24, 560.61, and 12.97, respectively). In a X/XO system, antioxidant properties of these polyphenols significantly inhibited XO activity (IC50 [mu g/mL], 17.36). These results indicated that total onion polyphenols showed promising antioxidant and anti-gout properties and might be used as potential, natural drugs against oxidative diseases after successful studies in vivo as well as clinical trials. (C) 2018 Production and hosting by Elsevier B.V. on behalf of King Saud University. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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