Review
Integrative & Complementary Medicine
Chenyang Ai, Yi Zou, Hao Liu, Zheqiong Yang, Jinlei Xi
Summary: The prevalence of allergic disorders has increased, leading to a lower quality of life for patients and a higher demand for drugs to treat these diseases. Traditional Chinese medicine offers distinct benefits in treating allergic illnesses, such as long-term treatment maintenance, prevention of disease recurrence, and fewer adverse reactions. Recent developments in Chinese herbal formula, Chinese patent medicine, and active ingredients of traditional Chinese medicine have been analyzed, discussing their components, efficacy, and mechanisms of action. The importance of improving traditional Chinese herbal formulas and developing safe and effective Chinese patent medicines is emphasized in the field of traditional Chinese medicine research.
AMERICAN JOURNAL OF CHINESE MEDICINE
(2023)
Article
Pharmacology & Pharmacy
Jianan Wang, Bo Zhou, Xiangdong Hu, Shuang Dong, Ming Hong, Jun Wang, Jian Chen, Jiuliang Zhang, Qiyun Zhang, Xiaohua Li, Alexander N. Shikov, Sheng Hu, Xuebo Hu
Summary: Herbal teas or drinks are traditional beverages used in many cultures, especially in Traditional Chinese Medicine. Studies have shown that certain herbs in these drinks can reduce inflammation and excessive body heat, with some combinations exhibiting detoxifying and synergistic effects. The integration of old traditional oriental methods with Western science has led to the development of herbal concoctions for detoxification and synergy.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Integrative & Complementary Medicine
Jillian L. Capodice, Barbara M. Chubak
Summary: Traditional Chinese Medicine (TCM) is a comprehensive medical system that has been developed over thousands of years and is utilized in the treatment of COVID-19. This paper highlights the use of TCM in treating COVID-19, discussing concepts and challenges of integrating TCM into medical settings.
Review
Pharmacology & Pharmacy
Liu Liu, Lei Zhang, Ming Li
Summary: Lupus nephritis is a renal disease caused by systemic lupus erythematosus and has serious implications for patients. Traditional Chinese medicine has shown promising effects in alleviating the symptoms and improving the prognosis of LN patients. This review provides supplementary evidence for the development of TCM treatment for LN and serves as a reference for future research and clinical practice.
FRONTIERS IN PHARMACOLOGY
(2022)
Review
Plant Sciences
Liangshuai Liu, Heping Li, Guosheng Tan, Zhenjiang Ma
Summary: This study reviewed the use of traditional Chinese herbal medicine in treating amenorrhea caused by antipsychotic drugs and conducted a meta-analysis. The results showed that Chinese herbal medicine can effectively treat this condition, although it may take a long time to achieve satisfactory effectiveness.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Review
Pharmacology & Pharmacy
Shan Wu, Chuanchi Wang, Dong Bai, Nanjie Chen, Jingqing Hu, Junhua Zhang
Summary: With the introduction of clinical epidemiology and evidence-based medicine, Traditional Chinese Herbal Medicine (TCHM) in China has improved and internationalization of Traditional Chinese Medicine (TCM) has accelerated. Many Chinese drug products have been approved for marketing in other countries, and several Chinese herbal preparations have been investigated in phase III clinical trials. However, international multi-center clinical trials of TCHM are rare and improvement in evaluation techniques and methods that meet international standards and TCHM characteristics is required.
FRONTIERS IN PHARMACOLOGY
(2023)
Review
Integrative & Complementary Medicine
Purumea Jun, Endang Rahmat, Chang-Hyun Han, Changsop Yang, Youngmin Kang
Summary: The decline in birth rates is a serious issue globally, with many countries implementing national programs to increase birth rates using traditional medicines. This review analyzed and compared herbal medicines from traditional Chinese medicine (TCM) and traditional Indonesian medicine (TIM) that pregnant women should avoid for preventing miscarriage and maintaining safety. Despite their differences, TCM and TIM share similarities in concept and treatment, especially regarding herbal medicines, making this review a useful reference for pregnant women to consume herbal medicines safely.
CHINESE JOURNAL OF INTEGRATIVE MEDICINE
(2021)
Article
Neurosciences
Qin Ru, Qi Xiong, Xiang Tian, Congyue Xu, Can Li, Lin Chen, Yuxiang Wu
Summary: This study investigated the therapeutic effect and mechanism of a candidate Chinese herbal medicine (CCHM) on methamphetamine (METH) addiction using network pharmacology and molecular docking methods. The results showed that CCHM effectively inhibited METH-induced conditioned place preference (CPP) behaviors in mice and identified several key targets and active ingredients.
FRONTIERS IN MOLECULAR NEUROSCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Muhammad Harith Zulkifli, Zafirah Liyana Abdullah, Nur Intan Saidaah Mohamed Yusof, Fazlin Mohd Fauzi
Summary: This article summarizes three in silico approaches for toxicity studies of Traditional Chinese medicine (TCM) herbal medicine, including machine learning, network toxicology, and molecular docking. Although these methods can provide data-driven toxicity prediction validated in vitro and/or in vivo, they are limited to single compound analysis and specific types of toxicity. Future studies should involve testing combinations of compounds to improve in silico toxicity modeling of TCM compounds.
CURRENT OPINION IN STRUCTURAL BIOLOGY
(2023)
Review
Plant Sciences
Ya-Ting Wang, Xiao-Le Wang, Zhen-Zhen Wang, Lan Lei, Die Hu, Yi Zhang
Summary: This review summarizes the antidepressant mechanisms of Xiao-Yao-San (XYS) and its active ingredients, which are reportedly correlated with monoamine neurotransmitter regulation, synaptic plasticity, and hypothalamic-pituitary-adrenal axis. XYS plays a critical role in the treatment of depression by regulating several factors and pathways. However, more clinical and animal studies are needed to further investigate the antidepressant function of XYS and provide more evidence and recommendations for its clinical application.
Review
Pharmacology & Pharmacy
Yiwen Li, Yanfei Liu, Jing Cui, Hui Zhao, Yue Liu, Luqi Huang
Summary: In recent years, there has been a significant increase in cohort studies focusing on the treatment of chronic non-communicable diseases with traditional Chinese medicine, particularly in the areas of tumor, cardiovascular, and cerebrovascular diseases. While the overall quality of cohort studies needs improvement, there has been a noticeable growth in the number of studies in the past 5 years.
FRONTIERS IN PHARMACOLOGY
(2021)
Review
Biochemistry & Molecular Biology
Jose M. Prieto, Guillermo R. Schinella
Summary: This experimental review explores the relationship between Traditional Chinese Medicine (TCM) herbal drugs and lipid peroxidation in the context of topical inflammation. The study finds that certain herbal drugs with bitter and cold properties inhibit both lipid peroxidation and eicosanoids production, while sweet drugs specifically inhibit eicosanoids production. The therapeutic value of other drugs may be based on their actions on the Qi. The study suggests potential translation between the two medical systems and provides insights for the treatment of skin conditions.
Review
Biochemistry & Molecular Biology
Blanca Ibanez, Ana Melero, Alegria Montoro, Juan F. Merino-Torres, Jose M. Soriano, Nadia San Onofre
Summary: In recent years, there has been increasing interest in finding natural radioprotectors to mitigate the harmful effects of radiation. This review examines herbal preparations from Ayurvedic, Traditional Chinese, and Kampo Medicines that have demonstrated potential radioprotective effects. Ten herbal preparations, including Abana, Amalakyadi Churna, Amritaprasham, Brahma, Bu-zhong-yi-qi-tang (BZYQT), Chyavanaprasha, Cystone, Geriforte, Mentat, and Triphala, are highlighted for their potential radioprotective properties. Exploring the ethnobotany of traditional Asian medicine may lead to the discovery of new active compounds with radioprotective properties.
Review
Plant Sciences
Myong Hak Ri, Yue Xing, Hong Xiang Zuo, Ming Yue Li, Hong Lan Jin, Juan Ma, Xuejun Jin
Summary: This review summarizes the regulatory mechanisms of natural compounds derived from traditional Chinese herbal medicines on the microglial response in animal models of ischemic stroke. The findings suggest that these compounds attenuate the M1 phenotype of microglia, which is involved in detrimental inflammatory response, while enhancing the neuroprotective M2 phenotype. Clinical trials also show significant and safe therapeutic effects, but further well-designed studies are needed.
Article
Environmental Sciences
Yi Wang, Yuan Li, Shuai Yang, Qi-Hao Wang, Shao-Cheng Si, Han-Yi Mei, Guo-Ming Liu, Xiang-Liang Pan, Yong-Ming Luo
Summary: Soil washing is an effective method for removing heavy metals from farmland soil, and the choice of washing agents is crucial for the efficiency of the removal. This study tested the potential of three residues of traditional Chinese herbal medicine extracts for Cd removal and identified the optimal conditions. The results showed that the extract from Prunus mume residues was a more feasible and environmentally friendly washing agent.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Clinical Neurology
Yihui Xu, Wei Lin, Shuifen Ye, Huajin Wang, Tingting Wang, Youyan Su, Liangning Wu, Yuanwang Wang, Qian Xu, Chuanshan Xu, Jing Cai
PARKINSONS DISEASE
(2017)
Article
Environmental Sciences
Ze Liu, Seyedahmad Hosseinzadeh, Niels Wardenier, Yannick Verheust, Michael Chys, Stijn Van Hulle
ENVIRONMENTAL TECHNOLOGY
(2019)
Article
Environmental Sciences
Ze Liu, Li Li, Ningning Shao, Tao Hu, Le Han, Dongmin Wang
ENVIRONMENTAL TECHNOLOGY
(2020)
Article
Integrative & Complementary Medicine
Yao Lin, Lanfang Tang, Peizhen Huang, Ting Liu, Jianan Zhong, Qian Xu, Xiyu Li, Youning Lin, Shaojian Xiao, Jing Cai
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
(2020)
Article
Integrative & Complementary Medicine
Qian Xu, Shasha Yang, Fangzhen Wu, Yao Lin, Jianan Zhong, Lanfang Tang, Xuefeng Hu, Jing Cai
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
(2020)