Phosphorylated α-Synuclein-Copper Complex Formation in the Pathogenesis of Parkinson’s Disease
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Phosphorylated α-Synuclein-Copper Complex Formation in the Pathogenesis of Parkinson’s Disease
Authors
Keywords
-
Journal
Parkinsons Disease
Volume 2017, Issue -, Pages 1-9
Publisher
Hindawi Limited
Online
2017-11-24
DOI
10.1155/2017/9164754
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Oligomeric and phosphorylated alpha-synuclein as potential CSF biomarkers for Parkinson’s disease
- (2016) Nour K. Majbour et al. Molecular Neurodegeneration
- α-Synuclein–induced lysosomal dysfunction occurs through disruptions in protein trafficking in human midbrain synucleinopathy models
- (2016) Joseph R. Mazzulli et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- LK6/Mnk2a is a new kinase of alpha synuclein phosphorylation mediating neurodegeneration
- (2015) Shiqing Zhang et al. Scientific Reports
- Efficient Modification of Alpha-Synuclein Serine 129 by Protein Kinase CK1 Requires Phosphorylation of Tyrosine 125 as a Priming Event
- (2014) Jonas Kosten et al. ACS Chemical Neuroscience
- Linking alpha-synuclein phosphorylation to reactive oxygen species formation and mitochondrial dysfunction in SH-SY5Y cells
- (2014) Rita Perfeito et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Copper and Copper Proteins in Parkinson’s Disease
- (2014) Sergio Montes et al. Oxidative Medicine and Cellular Longevity
- Modelling Ser129 Phosphorylation Inhibits Membrane Binding of Pore-Forming Alpha-Synuclein Oligomers
- (2014) Georg Sebastian Nübling et al. PLoS One
- Crosstalk between the proteasome system and autophagy in the clearance of α-synuclein
- (2013) Fang Yang et al. ACTA PHARMACOLOGICA SINICA
- G51D α-synuclein mutation causes a novel Parkinsonian-pyramidal syndrome
- (2013) Suzanne Lesage et al. ANNALS OF NEUROLOGY
- The mammalian copper transporters CTR1 and CTR2 and their roles in development and disease
- (2013) Natalie K.Y. Wee et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Alpha-synuclein p.H50Q, a novel pathogenic mutation for Parkinson's disease
- (2013) Silke Appel-Cresswell et al. MOVEMENT DISORDERS
- Disruption of Protein Quality Control in Parkinson's Disease
- (2013) C. Cook et al. Cold Spring Harbor Perspectives in Medicine
- Protein degradation pathways in Parkinson’s disease: curse or blessing
- (2012) Darius Ebrahimi-Fakhari et al. ACTA NEUROPATHOLOGICA
- Bioinorganic chemistry of copper coordination to alpha-synuclein: Relevance to Parkinson's disease
- (2012) Andrés Binolfi et al. COORDINATION CHEMISTRY REVIEWS
- Biomarkers of Protein Oxidation in Human Disease
- (2012) A. Garcia-Garcia et al. CURRENT MOLECULAR MEDICINE
- Suppression of α-synuclein toxicity and vesicle trafficking defects by phosphorylation at S129 in yeast depends on genetic context
- (2012) Vicente Sancenon et al. HUMAN MOLECULAR GENETICS
- Phosphorylation of α-Synuclein Protein at Ser-129 Reduces Neuronal Dysfunction by Lowering Its Membrane Binding Property inCaenorhabditis elegans
- (2012) Tomoki Kuwahara et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phosphorylated -Synuclein in Parkinson's Disease
- (2012) Y. Wang et al. Science Translational Medicine
- Increased α-synuclein phosphorylation and nitration in the aging primate substantia nigra
- (2012) A L McCormack et al. Cell Death & Disease
- Phosphorylation of α-Synuclein at Y125 and S129 Alters Its Metal Binding Properties: Implications for Understanding the Role of α-Synuclein in the Pathogenesis of Parkinson’s Disease and Related Disorders
- (2011) Yu Lu et al. ACS Chemical Neuroscience
- Epidemiology and etiology of Parkinson’s disease: a review of the evidence
- (2011) Karin Wirdefeldt et al. EUROPEAN JOURNAL OF EPIDEMIOLOGY
- Authentically Phosphorylated -Synuclein at Ser129 Accelerates Neurodegeneration in a Rat Model of Familial Parkinson's Disease
- (2011) H. Sato et al. JOURNAL OF NEUROSCIENCE
- Role of metal ions in aggregation of intrinsically disordered proteins in neurodegenerative diseases
- (2011) Leonid Breydo et al. Metallomics
- Copper(ii) enhances membrane-bound α-synuclein helix formation
- (2011) Heather R. Lucas et al. Metallomics
- Bioinorganic Chemistry of Parkinson’s Disease: Structural Determinants for the Copper-Mediated Amyloid Formation of Alpha-Synuclein
- (2010) Andrés Binolfi et al. INORGANIC CHEMISTRY
- Lysosomal Degradation of α-Synucleinin Vivo
- (2010) Sally K. Mak et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phosphorylated α-Synuclein at Ser-129 Is Targeted to the Proteasome Pathway in a Ubiquitin-independent Manner
- (2010) Youhei Machiya et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Pathologic Cascade Leading to Synaptic Dysfunction in -Synuclein-Induced Neurodegeneration
- (2010) D. A. Scott et al. JOURNAL OF NEUROSCIENCE
- Phosphorylation at S87 Is Enhanced in Synucleinopathies, Inhibits -Synuclein Oligomerization, and Influences Synuclein-Membrane Interactions
- (2010) K. E. Paleologou et al. JOURNAL OF NEUROSCIENCE
- Metalloproteomics and metal toxicology of α-synuclein
- (2010) Aaron Santner et al. Metallomics
- -Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro
- (2010) J. Burre et al. SCIENCE
- Phosphorylation of α-synuclein upregulates tyrosine hydroxylase activity in MN9D cells
- (2009) Bo Wu et al. ACTA HISTOCHEMICA
- Metal binding to alpha-synuclein peptides and its contribution to toxicity
- (2009) David R. Brown BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Parkinson's disease: from monogenic forms to genetic susceptibility factors
- (2009) S. Lesage et al. HUMAN MOLECULAR GENETICS
- Relationship between alpha synuclein phosphorylation, proteasomal inhibition and cell death: relevance to Parkinson’s disease pathogenesis
- (2009) Kai-Yin Chau et al. JOURNAL OF NEUROCHEMISTRY
- α-Synuclein S129 Phosphorylation Mutants Do Not Alter Nigrostriatal Toxicity in a Rat Model of Parkinson Disease
- (2009) Nikolaus R. McFarland et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Products of Cu(ii)-catalyzed oxidation of α-synuclein fragments containing M1-D2and H50residues in the presence of hydrogen peroxide
- (2008) Teresa Kowalik-Jankowska et al. DALTON TRANSACTIONS
- Serine 129 Phosphorylation of α-Synuclein Induces Unfolded Protein Response-mediated Cell Death
- (2008) Naoto Sugeno et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Wild Type α-Synuclein Is Degraded by Chaperone-mediated Autophagy and Macroautophagy in Neuronal Cells
- (2008) Tereza Vogiatzi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phosphorylation at Ser-129 but Not the Phosphomimics S129E/D Inhibits the Fibrillation of α-Synuclein
- (2008) Katerina E. Paleologou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Polo-like Kinase 2 (PLK2) Phosphorylates α-Synuclein at Serine 129 in Central Nervous System
- (2008) Kelly J. Inglis et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dopamine-modified α-synuclein blocks chaperone-mediated autophagy
- (2008) Marta Martinez-Vicente et al. JOURNAL OF CLINICAL INVESTIGATION
- Specificity and Regulation of Casein Kinase-Mediated Phosphorylation of α-Synuclein
- (2008) Elisa A. Waxman et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Site-Specific Interactions of Cu(II) with α and β-Synuclein: Bridging the Molecular Gap between Metal Binding and Aggregation
- (2008) Andrés Binolfi et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The phosphorylation state of Ser-129 in human -synuclein determines neurodegeneration in a rat model of Parkinson disease
- (2008) O. S. Gorbatyuk et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search