4.6 Article

Synergistic and targeted drug delivery based on nano-CeO2 capped with galactose functionalized pillar[5]arene via host-guest interactions

Journal

JOURNAL OF MATERIALS CHEMISTRY B
Volume 5, Issue 19, Pages 3483-3487

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c7tb00752c

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Funding

  1. National Natural Science Foundation of China [NSFC 21572181, NSFC 31270861]

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A smart drug delivery system based on porous CeO2 nano-rods (CeONRs) capped with galactose functionalized pillar[5] arene via host-guest interactions has been constructed, which showed GSH-responsiveness, synergism with anticancer drugs and cancer targeting ability resulting from its disulphide unit, ceria properties and galactose units, respectively.

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