Redox/pH dual-sensitive hybrid micelles for targeting delivery and overcoming multidrug resistance of cancer

Smart Superstructures with Ultrahigh pH-Sensitivity for Targeting Acidic Tumor Microenvironment: Instantaneous Size Switching and Improved Tumor Penetration

(2016) Hong-Jun Li et al.   ACS Nano

Dopamine-assisted deposition of poly (ethylene imine) for efficient heparinization

(2016) Rifang Luo et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Reconstituted high density lipoprotein mediated targeted co-delivery of HZ08 and paclitaxel enhances the efficacy of paclitaxel in multidrug-resistant MCF-7 breast cancer cells

(2016) Fangrong Zhang et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Reversal of multidrug resistance in breast cancer MCF-7/ADR cells by h-R3-siMDR1-PAMAM complexes

(2016) Jun Li et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

A safe, simple and efficient doxorubicin prodrug hybrid micelle for overcoming tumor multidrug resistance and targeting delivery

(2016) Yuling Bao et al.   JOURNAL OF CONTROLLED RELEASE

10-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Localized Prostate Cancer

(2016) Freddie C. Hamdy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Reversal of doxorubicin resistance in breast cancer by mitochondria-targeted pH-responsive micelles

(2015) Pengcheng Yu et al.   Acta Biomaterialia

Enzymatically and Reductively Degradable α-Amino Acid-Based Poly(ester amide)s: Synthesis, Cell Compatibility, and Intracellular Anticancer Drug Delivery

(2015) Huanli Sun et al.   BIOMACROMOLECULES

Reversion of multidrug resistance by a pH-responsive cyclodextrin-derived nanomedicine in drug resistant cancer cells

(2015) Qing Shi et al.   BIOMATERIALS

Roles of ligand and TPGS of micelles in regulating internalization, penetration and accumulation against sensitive or resistant tumor and therapy for multidrug resistant tumors

(2015) Ai-ting Wang et al.   BIOMATERIALS

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Dual Stimuli-Responsive Poly(β-amino ester) Nanoparticles for On-Demand Burst Release

(2015) Jung Seok Lee et al.   MACROMOLECULAR BIOSCIENCE

Redox- and pH-Sensitive Polymeric Micelles Based on Poly(β-amino ester)-Grafted Disulfide Methylene Oxide Poly(ethylene glycol) for Anticancer Drug Delivery

(2015) Quang Nam Bui et al.   MACROMOLECULES

Enhance Cancer Cell Recognition and Overcome Drug Resistance Using Hyaluronic Acid and α-Tocopheryl Succinate Based Multifunctional Nanoparticles

(2015) Desheng Liang et al.   MOLECULAR PHARMACEUTICS

Nanostructure controlled sustained delivery of human growth hormone using injectable, biodegradable, pH/temperature responsive nanobiohybrid hydrogel

(2015) Narendra K. Singh et al.   Nanoscale

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

Anticancer drug nanomicelles formed by self-assembling amphiphilic dendrimer to combat cancer drug resistance

(2015) Tuo Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MDR1 siRNA loaded hyaluronic acid-based CD44 targeted nanoparticle systems circumvent paclitaxel resistance in ovarian cancer

(2015) Xiaoqian Yang et al.   Scientific Reports

Role of the Breast Cancer Resistance Protein (BCRP/ABCG2) in Drug Transport—an Update

(2014) Qingcheng Mao et al.   AAPS Journal

Trigger-responsive, fast-degradable poly(β-amino ester)s for enhanced DNA unpackaging and reduced toxicity

(2014) Xiaojian Deng et al.   BIOMATERIALS

A TPGS-incorporating nanoemulsion of paclitaxel circumvents drug resistance in breast cancer

(2014) Huihui Bu et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Stimuli-sensitive nanopreparations for combination cancer therapy

(2014) Aditi Jhaveri et al.   JOURNAL OF CONTROLLED RELEASE

d-α-Tocopherol Polyethylene Glycol Succinate-Based Redox-Sensitive Paclitaxel Prodrug for Overcoming Multidrug Resistance in Cancer Cells

(2014) Yuling Bao et al.   MOLECULAR PHARMACEUTICS

Folic acid-conjugated hollow mesoporous silica/CuS nanocomposites as a difunctional nanoplatform for targeted chemo-photothermal therapy of cancer cells

(2014) Xijian Liu et al.   Journal of Materials Chemistry B

pH-Sensitive Docetaxel-Loaded d-α-Tocopheryl Polyethylene Glycol Succinate–Poly(β-amino ester) Copolymer Nanoparticles for Overcoming Multidrug Resistance

(2013) Shuang Zhao et al.   BIOMACROMOLECULES

Ligand-Directed Reduction-Sensitive Shell-Sheddable Biodegradable Micelles Actively Deliver Doxorubicin into the Nuclei of Target Cancer Cells

(2013) Yinan Zhong et al.   BIOMACROMOLECULES

Chitosan-g-TPGS Nanoparticles for Anticancer Drug Delivery and Overcoming Multidrug Resistance

(2013) Yuanyuan Guo et al.   MOLECULAR PHARMACEUTICS

Dextran-based redox-responsive doxorubicin prodrug micelles for overcoming multidrug resistance

(2013) Peng Liu et al.   Polymer Chemistry

Redox/pH dual stimuli-responsive biodegradable nanohydrogels with varying responses to dithiothreitol and glutathione for controlled drug release

(2012) Yuan-Jia Pan et al.   BIOMATERIALS

Vitamin E TPGS as a molecular biomaterial for drug delivery

(2012) Zhiping Zhang et al.   BIOMATERIALS

Vitamin E D-α-tocopheryl polyethylene glycol 1000 succinate-based nanomedicine

(2012) Zhiping Zhang et al.   Nanomedicine

Precise control of intracellular drug release and anti-tumor activity of biodegradable micellar drugs via reduction-sensitive shell-shedding

(2012) Wei Wang et al.   Soft Matter

Multifunctional nanoassemblies for vincristine sulfate delivery to overcome multidrug resistance by escaping P-glycoprotein mediated efflux

(2011) Peng Zhang et al.   BIOMATERIALS

Multifunctional Pluronic P123/F127 mixed polymeric micelles loaded with paclitaxel for the treatment of multidrug resistant tumors

(2011) Wei Zhang et al.   BIOMATERIALS

Multiple Drug Resistance Mechanisms in Cancer

(2010) Bruce C. Baguley   MOLECULAR BIOTECHNOLOGY