Article
Psychology, Biological
Igor Grossmann, Amanda A. Rotella, Cendri Hutcherson, Konstantyn Sharpinskyi, Michael E. W. Varnum, Sebastian K. Achter, Mandeep Dhami, Xinqi Evie Guo, Mane R. Kara-Yakoubian, David Mandel, Louis Raes, Louis Tay, Aymeric Vie, Lisa Wagner, Matus Adamkovic, Arash Arami, Patricia Arriaga, Kasun Bandara, Gabriel Banik, Frantisek Bartos, Ernest Baskin, Christoph Bergmeir, Michal K. Bialek, Caroline T. Borsting, Dillon M. Browne, Eugene Caruso, Rong Chen, Bin-Tzong J. Chie, William N. Chopik, Robert Collins, Chin Wen G. Cong, Lucian Conway, Matthew V. Davis, Martin A. Day, Nathan D. Dhaliwal, Justin Durham, Martyna T. Dziekan, Christian Elbaek, Eric Shuman, Marharyta Fabrykant, Mustafa T. Firat, Geoffrey A. Fong, Jeremy M. Frimer, Jonathan B. Gallegos, Simon Goldberg, Anton Gollwitzer, Julia Goyal, Lorenz D. Graf-Vlachy, Scott Gronlund, Sebastian Hafenbraedl, Andree J. Hartanto, Matthew J. Hirshberg, Matthew Hornsey, Piers D. L. Howe, Anoosha Izadi, Bastian Jaeger, Pavol Kacmar, Yeun Joon Kim, Ruslan G. Krenzler, Daniel Lannin, Hung-Wen Lin, Nigel Mantou Lou, Verity Y. Q. W. Lua, Aaron L. Lukaszewski, Albert R. Ly, Christopher Madan, Maximilian M. Maier, Nadyanna S. Majeed, David A. March, Abigail Marsh, Michal Misiak, Kristian Ove R. M. Myrseth, Jaime Napan, Jonathan Nicholas, Konstantinos Nikolopoulos, Tobias Otterbring, Mariola Paruzel-Czachura, Shiva Pauer, John Protzko, Quentin Raffaelli, Ivan Ropovik, Robert M. Ross, Yefim Roth, Espen Roysamb, Landon Schnabel, Astrid Schuetz, Matthias Seifert, A. T. Sevincer, Garrick T. Sherman, Otto Simonsson, Ming-Chien Sung, Chung-Ching Tai, Thomas Talhelm, Bethany A. Teachman, Philip E. Tetlock, Dimitrios Thomakos, Dwight C. K. Tse, Oliver J. Twardus, Joshua M. Tybur, Lyle Ungar, Daan Vandermeulen, Leighton Vaughan Williams, Hrag A. Vosgerichian, Qi Wang, Ke Wang, Mark E. Whiting, Conny E. Wollbrant, Tao Yang, Kumar Yogeeswaran, Sangsuk Yoon, Ventura R. Alves, Jessica R. Andrews-Hanna, Paul A. Bloom, Anthony Boyles, Loo Charis, Mingyeong Choi, Sean Darling-Hammond, Z. E. Ferguson, Cheryl R. Kaiser, Simon T. Karg, Alberto Lopez Ortega, Lori Mahoney, Melvin S. Marsh, Marcellin F. R. C. Martinie, Eli K. Michaels, Philip Millroth, Jeanean B. Naqvi, Weiting Ng, Robb B. Rutledge, Peter Slattery, Adam H. Smiley, Oliver Strijbis, Daniel Sznycer, Eli Tsukayama, Austin van Loon, Jan G. Voelkel, Margaux N. A. Wienk, Tom Wilkening
Summary: Social scientists' predictions of societal change are no more accurate than simple statistical models.
NATURE HUMAN BEHAVIOUR
(2023)
Review
Medicine, General & Internal
Emanuele Bozzalla-Cassione, Silvia Grignaschi, Blerina Xoxi, Terenzj Luvaro, Maria Immacolata Greco, Iolanda Mazzucchelli, Serena Bugatti, Carlomaurizio Montecucco, Antonio Manzo
Summary: Identifying pathological changes in chronic immune-inflammatory diseases is crucial for effective treatment strategies. However, the concept of flare, particularly in diseases like rheumatoid arthritis, is complex and lacks a comprehensive definition due to incomplete understanding of its underlying mechanisms. This review explores the pathophysiological processes of disease recrudescence in rheumatoid arthritis and the various definitions used to capture flare in clinical practice. Overall, the understanding of flare remains challenging and requires further investigation.
FRONTIERS IN MEDICINE
(2022)
Article
Engineering, Environmental
Yin Zhang, Fangxia Shen, Yi Yang, Mutong Niu, Da Chen, Longfei Chen, Shengqi Wang, Yunhao Zheng, Ye Sun, Feng Zhou, Hua Qian, Yan Wu, Tianle Zhu
Summary: This study analyzed the relationships between expiratory microbiotas and indoor microbiotas, and found a potential microbial exchange between the respiratory tract and indoor environment.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Agricultural Engineering
Wenya Zhao, Jie Gu, Xiaojuan Wang, Zilin Song, Ting Hu, Xiaoxia Dai, Jia Wang
Summary: The application of shrimp shell powder inhibits nitrification and denitrification, and reduces the abundances of metal resistance genes and nitrogen functional genes. The study also reveals complex relationships between heavy metals and nitrogen.
BIORESOURCE TECHNOLOGY
(2022)
Article
Anesthesiology
Lotte Sorensen, Johanna Maria van Dongen, Maurits van Tulder, Lisa Gregersen Oestergaard
Summary: The study aimed to identify prognostic factors for high societal costs and high costs of sick leave, and to assess the validity of the model across different diagnostic categories. The strongest prognostic factor for high societal costs was sick leave at the time of diagnosis. Other factors such as high age, comorbidity, and hospital admission the year before diagnosis were associated with high healthcare costs. The model showed good discriminative ability and explained a significant proportion of the outcome variation.
Article
Urban Studies
Leila Cornips, William Voorberg, Ingmar van Meerkerk, Roos Kramer
Summary: Co-production can potentially enhance urban vitality by establishing relationships between government institutions and local communities, allowing citizens and active residents to participate in the production of public services. However, there is limited empirical evidence to support the claims that co-production empowers citizens and promotes equality in service delivery. This article evaluates the extent to which co-production includes a representative portion of the population and contributes to enhanced inclusiveness, based on both quantitative and qualitative data from the Municipality of Rotterdam. The findings suggest that citizens with higher socioeconomic status are more likely to participate in co-production, indicating limited inclusiveness.
Article
Biochemistry & Molecular Biology
Yong Shao, Xiao-Bo Wang, Mei-Ling Zhang, Yan Liu, Sheng Wang, Bao-Lin Zhang, Min-Min Yang, Ming-Hai Yang, Ting Jia, Tian-Chun Pu, Yan Lu, He Liu, Zhe Xu, Bo Li, Ning Liu, Violet Magoma Onsongo, Dong-Dong Wu, Cheng-Lin Zhang, Jue Ruan, Yan Li
Summary: The spotted hyena is a large and unique terrestrial carnivore with complex social structure and scavenging lifestyle. Genomic analyses provide insights into the adaptive divergence in immune tolerance and potential genetic basis of social complexity in spotted hyenas.
MOLECULAR BIOLOGY AND EVOLUTION
(2022)
Article
Oncology
Roxanne Garaszczuk, Jean H. E. Yong, Zhuolu Sun, Claire de Oliveira
Summary: This study estimated the economic burden of cancer in Canada from a societal perspective. The findings revealed that cancer-related costs in Canada amounted to CAD 26.2 billion in 2021, with 30% of costs being borne by patients and their families. The study also highlighted that the highest costs were incurred in the first year after cancer diagnosis, reaching almost CAD 4.8 billion in 2021.
Article
Neurosciences
Brian M. M. Schilder, Elisa Navarro, Towfique Raj
Summary: This review provides an overview of the methods to prioritize potential causal variants and genes in Parkinson's Disease (PD) and summarizes the primary findings of previous studies. Additionally, recent efforts to integrate multiomics data for identifying likely pathogenic cell types and biological pathways implicated in PD pathogenesis are discussed.
NEUROBIOLOGY OF DISEASE
(2022)
Review
Multidisciplinary Sciences
M. McCauley, T. L. Goulet, C. R. Jackson, S. Loesgen
Summary: Microorganisms are crucial for the health and resilience of cnidarians. However, comparing cnidarian microbiomes across studies is challenging due to the variety of protocols used. In this study, researchers analyzed 12,010 cnidarian microbiome samples, along with samples from other organisms, to identify the factors influencing cnidarian microbiomes. They found a wide diversity of archaeal and bacterial phyla associated with cnidarians and identified key bacteria influenced by host characteristics, sampling depth, and ocean location. This systematic review provides a framework for understanding cnidarian microbiomes and their response to stress.
NATURE COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Abraham Castro Garcia, Shuo Cheng, Shawn E. Mcglynn, Jeffrey S. Cross
Summary: Machine learning methods were used to develop predictive models for bio-oil and solid residue yields in the depolymerization of lignin. The results showed that temperature and reaction time were the strongest predictors of experimental outcomes.
Article
Chemistry, Multidisciplinary
Abraham Castro Garcia, Shuo Cheng, Shawn E. McGlynn, Jeffrey S. Cross
Summary: In this study, machine learning methods were used to develop predictive models for bio-oil and solid residue yields in lignin depolymerization. The models achieved high accuracy and indicated that temperature and reaction time are the strongest predictors of experimental outcomes.
Article
Immunology
Franziska Darzentas, Monika Szczepanowski, Michaela Kotrova, Alina Hartmann, Thomas Beder, Nicola Goekbuget, Stefan Schwartz, Lorenz Bastian, Claudia Dorothea Baldus, Karol Pal, Nikos Darzentas, Monika Brueggemann
Summary: This study identified the clonal evolution of B-cell precursor acute lymphoblastic leukemia (BCP-ALL) using high-throughput sequencing and bespoke bioinformatics. The study found that IGH clonal evolution was present at diagnosis of BCP-ALL, which was linked to aberrant ongoing D-H/V-H-DJ(H) recombination and V-H replacement. Longitudinal follow-up analysis showed significant changes in the clonotypic composition. The study recommends following the marker DNJ-stem as the target for minimal residual disease (MRD) monitoring and tracking both VDJ(H) and DJ(H) family members.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Allergy
Laure M. Fijen, Philip C. G. Klein, Danny M. Cohn, Tim A. Kanters
Summary: This study aims to establish the entire burden of hereditary angioedema (HAE) which includes disease control, treatment satisfaction, reductions in quality of life, and societal costs. A cross-sectional survey was conducted on adult patients with HAE under treatment at the Dutch national center of reference, and the results provide valuable information for reimbursement decisions for HAE treatments.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
(2023)
Article
Energy & Fuels
M. Battashi, R. Farajzadeh, A. Bimani, M. Al Abri, R. Mjeni, V. Karpan, A. Fadili, J. van Wunnik
Summary: This paper introduces new mechanisms for oil recovery in heavy oil reservoirs with strong bottom aquifers using polymer injection. The cyclic injection strategy and intentional well shut-in improve polymer utilization and reduce polymer loss, leading to a favorable economic outcome.
JOURNAL OF PETROLEUM SCIENCE AND ENGINEERING
(2022)
Article
Health Care Sciences & Services
A. N. Varga, A. E. Guevara Morel, J. M. van Dongen, J. Lokkerbol, M. Lindeboom, M. W. van Tulder, L. M. Bouter, J. E. Bosmans
Summary: This paper discusses the collaboration challenges faced by epidemiologists and economists in health intervention research due to differences in terminology, and illustrates these differences with examples. The study aims to improve the quality of multidisciplinary collaboration between the two fields and assist researchers in selecting the most suitable analytical techniques for their research problems.
HEALTH SERVICES AND OUTCOMES RESEARCH METHODOLOGY
(2023)
Article
Orthopedics
Jesper Knoop, Jonas Esser, Joost Dekker, J. Willemijn de Joode, Raymond W. J. G. Ostelo, Johanna M. van Dongen
Summary: This study found that traditional Chinese medicine intervention can improve fasting blood glucose, glycated hemoglobin, and insulin resistance indices in patients with type 2 diabetes, compared to a control group. This provides more evidence supporting the use of traditional Chinese medicine for diabetes treatment.
BRAZILIAN JOURNAL OF PHYSICAL THERAPY
(2023)
Review
Mathematical & Computational Biology
Anita Natalia Varga, Alejandra Elizabeth Guevara Morel, Joran Lokkerbol, Johanna Maria van Dongen, Maurits Willem van Tulder, Judith Ekkina Bosmans
Summary: The aim of this article is to review the methods available for dealing with confounding in analyzing the effect of health care treatments with single-point exposure in observational data. The results show that there are significant differences in performance between different methods, and the performance of a specific method is highly dependent on the estimator used.
STATISTICS IN MEDICINE
(2023)
Article
Medicine, General & Internal
Rinske M. Bults, Johanna M. van Dongen, Raymond W. J. G. Ostelo, Jo Nijs, Doeke Keizer, C. Paul van Wilgen
Summary: This study examined the effectiveness of a primary care multidisciplinary treatment for chronic pain and found no significant differences compared to treatment as usual. However, there were statistically significant effects on patients' illness perceptions in favor of the intervention group.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Economics
Angela Jornada Ben, Johanna M. van Dongen, Aureliano Paolo Finch, Mohamed El Alili, Judith E. Bosmans
Summary: Inconsistent results have been found on the impact of using crosswalks versus EQ-5D value sets on reimbursement decisions. This simulation study further investigates the issue and finds that the use of crosswalks can significantly influence the cost-utility outcomes, potentially affecting reimbursement decisions.
EUROPEAN JOURNAL OF HEALTH ECONOMICS
(2023)
Article
Anesthesiology
Lotte Sorensen, Johanna Maria van Dongen, Maurits van Tulder, Lisa Gregersen Oestergaard
Summary: The study aimed to identify prognostic factors for high societal costs and high costs of sick leave, and to assess the validity of the model across different diagnostic categories. The strongest prognostic factor for high societal costs was sick leave at the time of diagnosis. Other factors such as high age, comorbidity, and hospital admission the year before diagnosis were associated with high healthcare costs. The model showed good discriminative ability and explained a significant proportion of the outcome variation.
Article
Medicine, Research & Experimental
Marlinde L. van Dijk, Leonie M. te Loo, Joyce Vrijsen, Inge van den Akker-scheek, Sanne Westerveld, Marjan Annema, Andre van Beek, Jip van den Berg, Alexander L. Boerboom, Adrie Bouma, Martine de Bruijne, Jeroen Crasborn, Johanna M. van Dongen, Anouk Driessen, Karin Eijkelenkamp, Nies Goelema, Jasmijn Holla, Johan de Jong, Anoek de Joode, Arthur Kievit, Josine van't Klooster, Hinke Kruizenga, Marike van der Leeden, Lilian Linders, Jenny Marks-Vieveen, Douwe Johannes Mulder, Femmy Muller, Femke van Nassau, Joske Nauta, Suzanne Oostvogels, Jessica Oude Sogtoen, Hidde P. van der Ploeg, Patrick Rijnbeek, Linda Schouten, Rhoda Schuling, Erik H. Serne, Simone Smuling, Maarten R. Soeters, Evert A. L. M. Verhagen, Johannes Zwerver, Rienk Dekker, Willem van Mechelen, Judith G. M. Jelsma
Summary: This study aims to assess the effectiveness and cost-effectiveness of a dedicated lifestyle front office (LFO) in promoting patient-centered lifestyle care and connecting with community-based lifestyle initiatives. Two parallel pragmatic randomized controlled trials will be conducted for cardiovascular disorders and musculoskeletal disorders.
Article
Economics
Angela Jornada Ben, Sylvia Pellekooren, Judith E. Bosmans, Raymond W. J. G. Ostelo, Esther T. Maas, Mohamed El Alili, Maurits W. van Tulder, Frank J. P. M. Huygen, Teddy Oosterhuis, Adri T. Apeldoorn, Miranda L. van Hooff, Johanna M. van Dongen
Summary: The study aimed to develop and validate approaches for mapping Oswestry Disability Index responses to 3-level version of EQ-5D utility values and evaluate their impact on cost-utility results compared with published regression models. Three response mapping approaches were developed and their performance was assessed. The results suggest that the developed approaches are not valid for estimating individual patients' utility values and may significantly affect cost-utility results.
Review
Rehabilitation
J. C. J. Huijbers, P. Coenen, G. L. B. Burchell, M. W. Coppieters, I. H. M. Steenhuis, J. H. Van Dieen, B. W. Koes, D. H. R. Kempen, J. R. Anema, I. Kingma, L. Voogt, C. M. Williams, J. M. Van Dongen, H. P. van der Ploeg, R. W. J. G. Ostelo, G. G. M. Scholten-Peeters
Summary: This systematic review found that combined lifestyle interventions are not superior to usual care for improving physical functioning, relieving pain, and improving lifestyle outcomes in overweight or obese individuals with persistent low-back pain. However, these interventions are likely to be more cost-effective in terms of healthcare, medication, and absenteeism costs compared to usual care.
MUSCULOSKELETAL SCIENCE AND PRACTICE
(2023)
Article
Psychiatry
S. A. J. Toonders, P. E. van Westrienen, N. J. de Wit, J. M. van Dongen, M. Gerrits, M. F. Pisters, C. Veenhof
Summary: It is important to provide appropriate treatment for individuals with an increased risk for developing chronic Persistent Somatic Symptoms (PSS) at an early stage to improve their quality of life and prevent high costs for society. In this study, an integrated blended care intervention was evaluated for its cost-effectiveness compared to usual care for patients with moderate PSS. The results showed no significant difference in total societal costs, but the intervention was found to be less costly and more effective in terms of subjective symptom impact and physical health.
JOURNAL OF PSYCHOSOMATIC RESEARCH
(2023)
Article
Economics
Angela Jornada Ben, Johanna M. van Dongen, Mohamed El Alili, Jonas L. Esser, Hana Marie Broulikova, Judith E. Bosmans
Summary: Trial-based economic evaluations face methodological challenges such as missing data, correlated costs and effects, baseline imbalances, and skewed costs and effects. Inappropriate methods can bias results and hinder healthcare decision-making. This tutorial provides step-by-step guidance on combining appropriate statistical methods to address these challenges using an R script, with theoretical background and illustration using a simulated trial-based economic evaluation.
Article
Public, Environmental & Occupational Health
Anne Slotegraaf, Marissa H. G. Gerards, Arie C. Verburg, Marian A. E. de van der Schueren, Hinke M. Kruizenga, Maud J. L. Graff, Edith H. C. Cup, Johanna G. Kalf, Antoine F. Lenssen, Willemijn M. Meijer, Renee A. Kool, Rob A. de Bie, Philip J. van der Wees, Thomas J. Hoogeboom
Summary: Patients recovering from COVID-19 who receive primary allied health care show progress in recovery but still face limitations in daily activities after 6 months. Baseline scores, hospital admission, and gender are associated with improvement between baseline and 6-month follow-up.
JMIR PUBLIC HEALTH AND SURVEILLANCE
(2023)
Article
Obstetrics & Gynecology
Tatiane Oliveira de Souza, Angela Jornada Ben, Johanna M. van Dongen, Judith E. Bosmans, Joao Sabino Lahorgue da Cunha-Filho
Summary: The study aimed to investigate the effectiveness and cost-effectiveness of two assisted reproduction technologies (ARTs), minimal ovarian stimulation IVF (MS-IVF) and conventional ovarian stimulation IVF (C-IVF), from the payer's perspective. Although there were no positive effect differences between the two groups, MS-IVF may be cost-effective compared to C-IVF due to its relatively large cost savings.
JORNAL BRASILEIRO DE REPRODUCAO ASSISTIDA
(2023)
Article
Health Care Sciences & Services
Tjarco Koppenaal, Johanna M. van Dongen, Corelien J. J. Kloek, Remco M. Arensman, Cindy Veenhof, Martijn F. Pisters, Raymond W. J. G. Ostelo
Summary: This study aimed to evaluate the long-term effectiveness and cost-effectiveness of stratified blended physiotherapy (e-Exercise LBP) compared with face-to-face physiotherapy in patients with nonspecific low back pain (LBP). The study found no significant differences between the two treatment methods in terms of physical functioning and quality-adjusted life years (QALYs). However, stratified blended physiotherapy showed significant improvements in fear avoidance beliefs. Although the costs were higher for stratified blended physiotherapy, there were no significant differences compared to face-to-face physiotherapy.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Article
Anesthesiology
Bastiaan C. Ter Meulen, Johanna M. van Dongen, Esther Maas, Marinus H. van de Vegt, Johan Haumann, Henry C. Weinstein, Raymond Ostelo
Summary: The objective of this study was to evaluate the effectiveness of transforaminal epidural steroid injections (TESIs) in patients with acute sciatica. The study found that TESIs had a statistically significant effect in improving leg pain compared to usual care. However, there were no differences in other co-primary outcomes. Interestingly, it was discovered that transforaminal epidural injections were associated with less opioid use.
CLINICAL JOURNAL OF PAIN
(2023)
