A muscle-specific MuRF1-E2 network requires stabilization of MuRF1-E2 complexes by telethonin, a newly identified substrate

Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C

(2016) Nicholas G. Brown et al.   CELL

E2 enzymes: more than just middle men

(2016) Mikaela D Stewart et al.   CELL RESEARCH

UBE2D2 is not involved in MuRF1-dependent muscle wasting during hindlimb suspension

(2016) Cécile Polge et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Novel mutation in TCAP manifesting with asymmetric calves and early-onset joint retractions

(2016) Carlos Pablo de Fuenmayor-Fernández de la Hoz et al.   NEUROMUSCULAR DISORDERS

Prevalence and clinical impact of cachexia in chronic illness in Europe, USA, and Japan: facts and numbers update 2016

(2016) Stephan von Haehling et al.   Journal of Cachexia Sarcopenia and Muscle

Ethical guidelines for publishing in the Journal of Cachexia, Sarcopenia and Muscle: update 2015

(2015) Stephan von Haehling et al.   Journal of Cachexia Sarcopenia and Muscle

UBE2B is implicated in myofibrillar protein loss in catabolic C2C12 myotubes

(2015) Cécile Polge et al.   Journal of Cachexia Sarcopenia and Muscle

Factors associated with skeletal muscle mass, sarcopenia, and sarcopenic obesity in older adults: a multi-continent study

(2015) Stefanos Tyrovolas et al.   Journal of Cachexia Sarcopenia and Muscle

Role of E2-Ub-conjugating enzymes during skeletal muscle atrophy

(2015) Cecile Polge et al.   Frontiers in Physiology

The Ubiquitin-Conjugating Enzyme, UbcM2, Is Restricted to Monoubiquitylation by a Two-Fold Mechanism That Involves Backside Residues of E2 and Lys48 of Ubiquitin

(2014) Linda Nguyen et al.   BIOCHEMISTRY

Crystal structure of the PRC1 ubiquitylation module bound to the nucleosome

(2014) Robert K. McGinty et al.   NATURE

Molecular basis for the fold organization and sarcomeric targeting of the muscle atrogin MuRF1

(2014) B. Franke et al.   Open Biology

Comprehensive Ubiquitin E2 Profiling of Ten Ubiquitin E3 Ligases

(2013) Jeffrey G. Marblestone et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Deciphering the ubiquitin proteome: Limits and advantages of high throughput global affinity purification-mass spectrometry approaches

(2013) Cécile Polge et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Phosphoregulation of the Titin-cap Protein Telethonin in Cardiac Myocytes

(2013) Alexandra J. Candasamy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A New Protein-Protein Interaction Sensor Based on Tripartite Split-GFP Association

(2013) Stéphanie Cabantous et al.   Scientific Reports

A Human Ubiquitin Conjugating Enzyme (E2)-HECT E3 Ligase Structure-function Screen

(2012) Yi Sheng et al.   MOLECULAR & CELLULAR PROTEOMICS

Functional interactions between ubiquitin E2 enzymes and TRIM proteins

(2011) Luisa M. Napolitano et al.   BIOCHEMICAL JOURNAL

Telethonin Deficiency Is Associated With Maladaptation to Biomechanical Stress in the Mammalian Heart

(2011) Ralph Knöll et al.   CIRCULATION RESEARCH

Muscle actin is polyubiquitinylated in vitro and in vivo and targeted for breakdown by the E3 ligase MuRF1

(2011) Cécile Polge et al.   FASEB JOURNAL

E2s: structurally economical and functionally replete

(2010) Dawn M. Wenzel et al.   BIOCHEMICAL JOURNAL

What Determines the Specificity and Outcomes of Ubiquitin Signaling?

(2010) Fumiyo Ikeda et al.   CELL

The E2 Ubiquitin-conjugating Enzymes Direct Polyubiquitination to Preferred Lysines

(2010) Yael David et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic interactions of proteins in complex networks: identifying the complete set of interacting E2s for functional investigation of E3-dependent protein ubiquitination

(2009) Devin E. Christensen et al.   FEBS Journal

Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network

(2009) G. Markson et al.   GENOME RESEARCH

Depletion of zebrafish Tcap leads to muscular dystrophy via disrupting sarcomere–membrane interaction, not sarcomere assembly

(2009) Ruilin Zhang et al.   HUMAN MOLECULAR GENETICS

During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation

(2009) Shenhav Cohen et al.   JOURNAL OF CELL BIOLOGY

Gene expression and muscle fiber function in a porcine ICU model

(2009) Varuna C. Banduseela et al.   PHYSIOLOGICAL GENOMICS

Structural Analysis of B-Box 2 from MuRF1: Identification of a Novel Self-Association Pattern in a RING-like Fold†‡

(2008) Michael Mrosek et al.   BIOCHEMISTRY

Atypical ubiquitin chains: new molecular signals. ‘Protein Modifications: Beyond the Usual Suspects’ Review Series

(2008) Fumiyo Ikeda et al.   EMBO REPORTS

Coordinate expression of the 19S regulatory complex and evidence for ubiquitin-dependent telethonin degradation in the unloaded soleus muscle

(2008) A.E. Heng et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

A Mutation in Telethonin Alters Nav1.5 Function

(2008) Amelia Mazzone et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MuRF1-dependent Regulation of Systemic Carbohydrate Metabolism as Revealed from Transgenic Mouse Studies

(2008) Stephanie Hirner et al.   JOURNAL OF MOLECULAR BIOLOGY

Muscle RING-Finger Protein-1 (MuRF1) as a Connector of Muscle Energy Metabolism and Protein Synthesis

(2007) Suguru Koyama et al.   JOURNAL OF MOLECULAR BIOLOGY