Article
Cardiac & Cardiovascular Systems
Alexander R. van Rosendael, Jeff M. Smit, Mohammed El'Mahdiui, Philippe J. van Rosendael, Melissa Leung, Victoria Delgado, Jeroen J. Bax
Summary: This study evaluated the association between left atrial epicardial fat and left atrial volume in patients with different types of atrial fibrillation (AF). The results showed that left atrial epicardial fat was larger in patients with paroxysmal AF, while larger left atrial volumes were associated with persistent/permanent AF.
Article
Cardiac & Cardiovascular Systems
Olga Shaihov-Teper, Eilon Ram, Nimer Ballan, Rafael Y. Brzezinski, Nili Naftali-Shani, Rula Masoud, Tamar Ziv, Nir Lewis, Yeshai Schary, La-Paz Levin-Kotler, David Volvovitch, Elchanan M. Zuroff, Sergei Amunts, Neta Regev-Rudzki, Leonid Sternik, Ehud Raanani, Lior Gepstein, Jonathan Leor
Summary: This study revealed, for the first time, a distinctive proinflammatory, profibrotic, and proarrhythmic signature of epicardial fat-derived extracellular vesicles in patients with atrial fibrillation, uncovering another pathway by which epicardial fat promotes the development of atrial myopathy and fibrillation.
Article
Cardiac & Cardiovascular Systems
Jing Zhu, Kaimin Zhuo, Bo Zhang, Zhen Xie, Wenjia Li
Summary: Gender has a significant impact on the prevalence and prognosis of atrial fibrillation. Women have a higher ratio of epicardial adipose tissue and higher recurrence rate after catheter ablation for atrial fibrillation.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Gilberto J. Aquino, Jordan Chamberlin, Basel Yacoub, Madison R. Kocher, Ismail Kabakus, Selcuk Akkaya, Megan Mercer, Jeffrey Waltz, Matthew Fiegel, Nathan Leaphart, Athira Jacob, Mehmet Akif Gulsun, James Gilkes, Joe Stephenson, Puneet Sharma, Pooyan Sahbaee, Joseph Schoepf, Stefan Zimmerman, Michael E. Field, Ali M. Agha, Jeremy R. Burt
Summary: This study evaluated the effectiveness of a novel AI algorithm for automated measurement of left atrial volumes and function using cardiac CT in patients with atrial fibrillation. The results showed that the AI algorithm was significantly faster than manual measurement and had comparable accuracy. It can be used as a useful tool for diagnosing and assessing the cardiac function of atrial fibrillation patients.
EUROPEAN RADIOLOGY
(2022)
Review
Cardiac & Cardiovascular Systems
Andrea Lorenzo Poggi, Benedicte Gaborit, Thomas Hellmut Schindler, Luca Liberale, Fabrizio Montecucco, Federico Carbone
Summary: Obesity is a heterogeneous condition that may have a closer link with cardiovascular disease burden and atrial fibrillation. Dysfunction of epicardial adipose tissue (EAT) due to ectopic fat deposition is associated with atrial remodelling and may play a significant role in the development and recurrence of atrial fibrillation. This study provides an updated understanding of the relationship between dysfunctional EAT, LA remodelling, and atrial fibrillation onset and recurrence.
Article
Medicine, General & Internal
Reinhard Kaufmann, Richard Rezar, Bernhard Strohmer, Bernhard Wernly, Michael Lichtenauer, Wolfgang Hitzl, Matthias Meissnitzer, Klaus Hergan, Marcel Granitz
Summary: By calculating the left atrial and left atrial appendage ejection fractions, it is possible to predict AF recurrence more sensitively after PVI. The left atrial function parameters are independent of the type of AF, providing useful predictors for AF recurrence.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Jennifer Mancio, Fabio Sousa-Nunes, Rafael Martins, Mariana Fragao-Marques, Gloria Conceicao, Guilherme Pessoa-Amorim, Antonio S. Barros, Catia Santa, Wilson Ferreira, Monica Carvalho, Isabel M. Miranda, Rui Vitorino, Ines Falcao-Pires, Bruno Manadas, Vasco Gama Ribeiro, Adelino Leite-Moreira, Nuno Bettencourt, Ricardo Fontes-Carvalho
Summary: The study found a correlation between abnormal epicardial adipose tissue and heart issues, including left atrial remodeling and post-operative atrial fibrillation. This provides a new direction for early prevention and treatment.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Pietro Spagnolo, Manuela Giglio, Daniela Di Marco, Paola M. Cannao, Eustachio Agricola, Paolo E. Della Bella, Caterina B. Monti, Francesco Sardanelli
Summary: A CCT protocol incorporating a 6-min delayed phase in addition to the standard angiographic phase is considered optimized for diagnosing LAA thrombi, with low radiation exposure.
EUROPEAN RADIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Stefano Grossi, Francesca Bianchi, Alessandro Blandino, Chiara Pintor, Antonino Tomasello, Barbara Mabritto, Giuseppe Musumeci
Summary: The combination of epicardial LAA occlusion and endo-epicardial ablation was found to be feasible and safe in the treatment of refractory AF, and may represent a new approach for patients who need LAA closure.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Medicine, General & Internal
Muktapha Sangsriwong, Gabriel Cismaru, Mihai Puiu, Gelu Simu, Sabina Istratoaie, Lucian Muresan, Gabriel Gusetu, Andrei Cismaru, Dana Pop, Dumitru Zdrenghea, Radu Rosu
Summary: There is a significant correlation between the left atrial AP diameter measured on echocardiography and the volume measured on CT, suggesting that the AP diameter may be sufficient in predicting cardiovascular outcomes associated with increased atrial volume.
Article
Cardiac & Cardiovascular Systems
Xiang-Nan Li, Jing-Xi Wang, Qing Wei, Xian-Bo Yu, Yu-Tao Zhou, Xiao-Yan Ma, Na Zhao, Bin Lu
Summary: Delayed enhancement cardiac CT scanning is reliable for the diagnosis of left atrial appendage thrombus but limited by scanning heterogeneity. In this study, we found that early contrast-enhanced CT scanning with 1 and 3-min delay phase significantly improved diagnostic efficiency and direct 3-min delayed scanning is suitable for high-risk patients.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Medicine, General & Internal
Zuolin Lu, Martijn J. Tilly, Elif Aribas, Daniel Bos, Sven Geurts, Bruno H. Stricker, Robert de Knegt, M. Arfan Ikram, Natasja M. S. de Groot, Trudy Voortman, Maryam Kavousi
Summary: The study found that different body fat depots were associated with the development of new-onset atrial fibrillation (AF). Total fat mass and abdominal fat mass were independently associated with AF, while the ratio of abdominal fat to hip fat showed an inverse association. These findings provide new insights into the pathogenesis and prevention of AF.
Article
Multidisciplinary Sciences
Yameng Shao, Lei Chen, Changjiang Xu, Beibei Gao, Dongdong Zhang, Chuanyi Sang, Chaoqun Zhang
Summary: This study explored the relationship between left atrial epicardial adipose tissue (LA-EAT) and left atrial appendage flow velocity (LAA-FV) in patients with nonvalvular atrial fibrillation (NV-AF). The results showed that left atrial low voltage zone, LA-EAT volume, left atrial appendage shape, left atrial volume index, and type of atrial fibrillation were independent predictors of LAA-FV in NV-AF patients.
SCIENTIFIC REPORTS
(2022)
Article
Cardiac & Cardiovascular Systems
Yaacoub Chahine, Fima Macheret, Karen Ordovas, Joonseok Kim, Patrick M. M. Boyle, Nazem Akoum
Summary: The volume of left atrial epicardial adipose tissue (EAT), assessed using cardiac magnetic resonance imaging, is independently associated with atrial fibrillation (AF) recurrence following catheter ablation. Integration of EAT with clinical risk factors improves prediction of AF recurrence.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Medicine, General & Internal
Tomasz Jadczyk, Jiri Wolf, Martin Pesl, Filip Soucek, Frantisek Lehar, Jiri Jez, Tomas Kulik, Bohdan Tyshchenko, Silvie Belaskova, Petr Ourednicek, Guido Caluori, Miroslav Novak, Zdenek Starek
Summary: This study developed and validated low-dose CT scanning protocols of the left atrium for radiofrequency catheter ablation (RFA) guidance. Optimized scanning protocols significantly reduced radiation dose without affecting contrast media and signal-to-noise ratio.
Article
Cardiac & Cardiovascular Systems
Ji Bak Kim, Byoung Geol Choi, Seung-Woon Rha
Summary: This study investigated the impact of nitrate therapy on the prognosis of patients with myocardial bridge and coexisting coronary artery spasm. The results showed that long-term nitrate administration did not reduce major adverse cardiovascular events but was associated with a higher incidence of recurrent angina requiring follow-up angiography.
Article
Cardiac & Cardiovascular Systems
Dong Geum Shin, Minwoo Lee, Jinhee Ahn, Sang-Jin Han, Hong Euy Lim
Summary: This study evaluated the procedural safety of a single bolus administration of heparin without ACT measurement during cryoballoon ablation in patients with uninterrupted NOAC intake.
JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Dong-Hyuk Cho, Yun Gi Kim, Jimi Choi, Hee-Dong Kim, Mi-Na Kim, Jaemin Shim, Jong-Il Choi, Young-Hoon Kim, Wan-Joo Shim, Seong-Mi Park
Summary: Impaired atrial functional reserve during exercise may indicate early-stage atrial cardiomyopathy in patients with paroxysmal atrial fibrillation (PAF) and is associated with AF recurrence. Atrial cardiomyopathy can occur independently of changes in LV function and even in patients with normal-sized left atria.
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
(2023)
Article
Cardiac & Cardiovascular Systems
Jeehoon Kang, Kyung Woo Park, Huijin Lee, Doyeon Hwang, Han-Mo Yang, Seung-Woon Rha, Jang-Whan Bae, Nam Ho Lee, Seung-Ho Hur, Jung-Kyu Han, Eun-Seok Shin, Bon-Kwon Koo, Hyo-Soo Kim
Summary: The HOST-EXAM Extended study investigated the long-term outcomes of antiplatelet monotherapy in patients who underwent percutaneous coronary intervention. It found that clopidogrel monotherapy was associated with lower rates of adverse clinical events compared to aspirin monotherapy in patients without clinical events for 12 ± 6 months after the procedure.
Article
Cardiac & Cardiovascular Systems
Chang-Hwan Yoon, Ju-Seung Kwun, Young Jin Choi, Jin Joo Park, Si-Hyuck Kang, Sun-Hwa Kim, Jung-Won Suh, Tae-Jin Youn, Myeong-Kon Kim, Kwang Soo Cha, Seung-Hwan Lee, Bum-Kee Hong, Seung-Woon Rha, Woong Chol Kang, Jae-Hwan Lee, Sang-Hyun Kim, In-Ho Chae
Summary: This study compared the long-term clinical outcomes of patients treated with ultrathin-strut biodegradable polymer sirolimus-eluting stents (BP-SES) and thick-strut biodegradable polymer biolimus-eluting stents (BP-BES). The results showed that the ultrathin-strut BP-SES had significantly lower target lesion failure rates and better outcomes compared to the thick-strut BP-BES.
CIRCULATION-CARDIOVASCULAR INTERVENTIONS
(2023)
Article
Cardiac & Cardiovascular Systems
Soohyung Park, Seung-Woon Rha, Byoung Geol Choi, Jang Hyun Cho, Sang Ho Park, Jin Bae Lee, Yong Hoon Kim, Sang Min Park, Jae Woong Choi, Ji Young Park, Eun-Seok Shin, Jae Beom Lee, Jon Suh, Jei Keon Chae, Young Jin Choi, Myung Ho Jeong, Kwang Soo Cha, Seung Wook Lee, Ung Kim, Gi Chang Kim, Woong-Gil Choi, Yun-Hyeong Cho, Deok-kyu Cho, Jihun Ahn, Soon-Yong Suh, Se Yeon Choi, Jae Kyeong Byun, Jin Ah Cha, Soo Jin Hyun, Ji Bak Kim, Cheol Ung Choi, Chang Gyu Park
Summary: This study compared the clinical outcomes of immediate and staged complete revascularization in patients with ST-segment elevation myocardial infarction and multivessel disease. The study found that the incidence of major adverse cardiovascular events was slightly higher in the immediate revascularization group compared to the staged revascularization group at 1-year follow-up. However, there were no significant differences in other clinical outcomes between the two groups. The study suggests that further large randomized clinical trials are needed to determine the optimal timing of complete revascularization for these patients.
AMERICAN HEART JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Yong Hoon Kim, Ae-Young Her, Seung-Woon Rha, Cheol Ung Choi, Byoung Geol Choi, Ji Bak Kim, Dong Oh Kang, Ji Young Park, Sang-Ho Park, Myung Ho Jeong
Summary: The clinical outcomes after NSTEMI were compared between patients with (SDT >= 24 h) and without (SDT < 24 h) delayed hospitalization, in both diabetic and non-diabetic patients. In the diabetic group, there was no significant difference in primary and secondary clinical outcomes between the SDT < 24 h and SDT >= 24 h groups. However, in the non-diabetic group, the rates of all-cause and cardiac death were significantly higher in the SDT >= 24 h group than in the SDT < 24 h group.
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
(2023)
Article
Cardiac & Cardiovascular Systems
Jinhee Ahn, Dong Geum Shin, Sang-Jin Han, Hong Euy Lim
Summary: The aim of this study was to investigate the safety and efficacy of fluoroless cryoballoon ablation for atrial fibrillation under intracardiac echocardiography guidance. The study showed that all patients underwent successful cryoballoon ablation, and the fluoroscopy time and radiation exposure were significantly lower in the fluoroless group. The follow-up results showed similar recurrence rates between the two groups. Therefore, intracardiac echocardiography-guided fluoroless cryoballoon ablation is a feasible strategy for treating atrial fibrillation.
Article
Cardiac & Cardiovascular Systems
Woo Jin Ahn, Seung-Woon Rha, Byoung Geol Choi, Myung Ho Jeong, KAMIR, NIH Investigators
Summary: This study aimed to investigate the impact of ACEI and ARB on 3-year clinical outcomes in elderly AMI patients without a history of hypertension who underwent successful PCI with DES. A total of 13,104 patients were included and divided into ACEI group and ARB group. The use of ACEI was associated with lower incidences of stroke and re-hospitalization due to HF compared to the use of ARB.
Article
Cardiac & Cardiovascular Systems
Moonki Jung, Kyeongmin Byeon, Ki-Woon Kang, Wang-Soo Lee, Sang Wook Kim, Yae Min Park, You Mi Hwang, Sung Ho Lee, Eun-Sun Jin, Seung-Young Roh, Jin Seok Kim, Jinhee Ahn, So-Ryoung Lee, Eue-Keun Choi, Min-Soo Ahn, Eun Mi Lee, Hwan-Cheol Park, Ki Hong Lee, Min Kim, Joon Hyouk Choi, Jum Suk Ko, Jin Bae Kim, Changsoo Kim, Gregory Y. H. Lip, Seung Yong Shin
Summary: This multicenter cohort study evaluated the clinical outcomes of different antithrombotic treatments in atrial fibrillation patients with non-gender CHA(2)DS(2)-VASc score 0-1. The study found that among patients with ABCD score ≥1, non-VKA oral anticoagulants showed significant net clinical benefits compared to other treatments.
JOURNAL OF ARRHYTHMIA
(2023)
Article
Cardiac & Cardiovascular Systems
Jeongduk Seo, Yae Min Park, Yong Hoon Shin, Albert Youngwoo Jang, Woong Chol Kang, Wook-Jin Chung, Young-Hoon Kim, In Suck Choi
Summary: Atrial fibrosis in the right atrium may be the mechanism behind atrial fibrillation and intra-atrial conduction delay. Scar homogenization in the right atrium can improve intra-atrial conduction delay.
ANNALS OF NONINVASIVE ELECTROCARDIOLOGY
(2023)
Article
Medicine, General & Internal
Soohyung Park, Byambakhand Battumur, Seo Yeon Yoon, Yohan Lee, Se Hyun Park, Kyuho Lee, Seungmin Back, Jieun Lee, Dong Oh Kang, Jah Yeon Choi, Seung-Young Roh, Jin Oh Na, Cheol Ung Choi, Jin Won Kim, Seung-Woon Rha, Chang Gyu Park, Eung Ju Kim
Summary: Exercise capacity is an independent predictor of cardiovascular events and mortality. This study compared the prognostic values of Korean and Western nomograms for exercise capacity in Korean patients with cardiovascular disease (CVD) and found that lower exercise capacity in Korean patients is associated with a higher risk of major adverse cardiovascular events.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2023)
Article
Medicine, Research & Experimental
Mohammad Iqbal, Iwan Cahyo Santosa Putra, Rizki Bunawan, Hanna Goenawan, Mohammad Rizki Akbar, Arief Sjamsulaksan Kartasasmita, Young Hoon Kim
Summary: This study shows that early cardiac remodeling may occur within 1 month after pacemaker implantation, as indicated by an increase in soluble suppression of tumorigenicity 2 (sST2) level. The sST2 level was significantly higher 1 month after implantation compared to before. Early detection of cardiac remodeling is important to prevent pacing induced cardiomyopathy.
Article
Medicine, General & Internal
Seung-Young Roh, Dae-In Lee, Kwang-No Lee, Jinhee Ahn, Yong-Soo Baek, Dong-Hyeok Kim, Jaemin Shim, Jong-Il Choi, Young-Hoon Kim
Summary: This study found that patients with atrial fibrillation (AF) have a higher left atrial pressure response (LAPR) to incremental pacing, which can predict left ventricular diastolic dysfunction. High E/e' values and body mass index were independent predictors of pacing-induced left atrial hypertension.
MEDICINA-LITHUANIA
(2023)
Article
Cardiac & Cardiovascular Systems
Hyo-Jeong Ahn, Myung-Jin Cha, Euijae Lee, So-Ryoung Lee, Eue-Keun Choi, Seongwook Han, Gi-Byung Nam, Jong-Il Choi, Hui-Nam Pak, Il-Young Oh, Dong-Gu Shin, Young Keun On, Sang Weon Park, Young-Hoon Kim, Seil Oh
Summary: This study investigated the recurrence of atrial fibrillation (AF) after radiofrequency catheter ablation (RFCA) in young patients. The results showed that patients under 60 years old had a higher rate of AF recurrence within 1 year after the procedure. These young patients may have distinct pathophysiology of AF and require more comprehensive management.
JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY
(2023)