Mechanisms and Regulation of Extracellular DNA Release and Its Biological Roles in Microbial Communities

Biofilm dispersion in Pseudomonas aeruginosa

(2016) Soo-Kyoung Kim et al.   JOURNAL OF MICROBIOLOGY

Chromosomal transformation inBacillus subtilisis a non-polar recombination reaction

(2016) Begoña Carrasco et al.   NUCLEIC ACIDS RESEARCH

Explosive cell lysis as a mechanism for the biogenesis of bacterial membrane vesicles and biofilms

(2016) Lynne Turnbull et al.   Nature Communications

Horizontal DNA Transfer Mechanisms of Bacteria as Weapons of Intragenomic Conflict

(2016) Nicholas J. Croucher et al.   PLOS BIOLOGY

Coordinated Bacteriocin Expression and Competence in Streptococcus pneumoniae Contributes to Genetic Adaptation through Neighbor Predation

(2016) Wei-Yun Wholey et al.   PLoS Pathogens

The Phenazine 2-Hydroxy-Phenazine-1-Carboxylic Acid Promotes Extracellular DNA Release and Has Broad Transcriptomic Consequences in Pseudomonas chlororaphis 30–84

(2016) Dongping Wang et al.   PLoS One

Presence of Extracellular DNA during Biofilm Formation by Xanthomonas citri subsp. citri Strains with Different Host Range

(2016) Marta Sena-Vélez et al.   PLoS One

The Quorum Sensing Inhibitor Hamamelitannin Increases Antibiotic Susceptibility of Staphylococcus aureus Biofilms by Affecting Peptidoglycan Biosynthesis and eDNA Release

(2016) Gilles Brackman et al.   Scientific Reports

Extracellular DNA Acidifies Biofilms and Induces Aminoglycoside Resistance in Pseudomonas aeruginosa

(2015) Mike Wilton et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Extracellular Vesicles of the Hyperthermophilic Archaeon “Thermococcus onnurineus” NA1T

(2015) Dong Hee Choi et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Uptake of extracellular DNA: Competence induced pili in natural transformation ofStreptococcus pneumoniae

(2015) Sandra Muschiol et al.   BIOESSAYS

Multifaceted roles of extracellular DNA in bacterial physiology

(2015) Dina Vorkapic et al.   CURRENT GENETICS

Important Contribution of the Novel LocuscomEBto Extracellular DNA-Dependent Staphylococcus lugdunensis Biofilm Formation

(2015) Nithya Babu Rajendran et al.   INFECTION AND IMMUNITY

Origin, dynamics, and implications of extracellular DNA pools in marine sediments

(2015) Andrea Torti et al.   Marine Genomics

Streptococcus gordonii comCDE (competence) operon modulates biofilm formation with Candida albicans

(2015) Alison A. Jack et al.   MICROBIOLOGY-SGM

Vibrio choleraephosphatases required for the utilization of nucleotides and extracellular DNA as phosphate sources

(2015) EmilyKate McDonough et al.   MOLECULAR MICROBIOLOGY

ComGA-RelA interaction and persistence in theBacillus subtilis K-state

(2015) Jeanette Hahn et al.   MOLECULAR MICROBIOLOGY

Pel is a cationic exopolysaccharide that cross-links extracellular DNA in thePseudomonas aeruginosabiofilm matrix

(2015) Laura K. Jennings et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Helicobacter pylori ATCC 43629/NCTC 11639 Outer Membrane Vesicles (OMVs) from Biofilm and Planktonic Phase Associated with Extracellular DNA (eDNA)

(2015) Rossella Grande et al.   Frontiers in Microbiology

Mycobacterium avium Possesses Extracellular DNA that Contributes to Biofilm Formation, Structural Integrity, and Tolerance to Antibiotics

(2015) Sasha J. Rose et al.   PLoS One

Iron Triggers λSo Prophage Induction and Release of Extracellular DNA in Shewanella oneidensis MR-1 Biofilms

(2014) Lucas Binnenkade et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Horizontal transfer of short and degraded DNA has evolutionary implications for microbes and eukaryotic sexual reproduction

(2014) Søren Overballe-Petersen et al.   BIOESSAYS

Biofilms formed by the archaeon Haloferax volcaniiexhibit cellular differentiation and social motility, and facilitate horizontal gene transfer

(2014) Scott Chimileski et al.   BMC BIOLOGY

Streptococcus mutans Extracellular DNA Is Upregulated during Growth in Biofilms, Actively Released via Membrane Vesicles, and Influenced by Components of the Protein Secretion Machinery

(2014) S. Liao et al.   JOURNAL OF BACTERIOLOGY

Extracellular vesicles produced by the Gram-positive bacteriumBacillus subtilisare disrupted by the lipopeptide surfactin

(2014) Lisa Brown et al.   MOLECULAR MICROBIOLOGY

Identification ofin vivoregulators of theVibrio cholerae xdsgene using a high-throughput genetic selection

(2014) EmilyKate McDonough et al.   MOLECULAR MICROBIOLOGY

DNA as a Phosphate Storage Polymer and the Alternative Advantages of Polyploidy for Growth or Survival

(2014) Karolin Zerulla et al.   PLoS One

Flagella-Mediated Adhesion and Extracellular DNA Release Contribute to Biofilm Formation and Stress Tolerance of Campylobacter jejuni

(2014) Sarah L. Svensson et al.   PLoS One

Extracellular DNA can preserve the genetic signatures of present and past viral infection events in deep hypersaline anoxic basins

(2014) C. Corinaldesi et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Extracellular DNA metabolism in Haloferax volcanii

(2014) Scott Chimileski et al.   Frontiers in Microbiology

The role of extracellular DNA in the establishment, maintenance and perpetuation of bacterial biofilms

(2013) Mira Okshevsky et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Recent insights into Candida albicans biofilm resistance mechanisms

(2013) Lotte Mathé et al.   CURRENT GENETICS

Secreted single-stranded DNA is involved in the initial phase of biofilm formation byNeisseria gonorrhoeae

(2013) Maria Zweig et al.   ENVIRONMENTAL MICROBIOLOGY

Extracellular DNA Release Acts as an Antifungal Resistance Mechanism in Mature Aspergillus fumigatus Biofilms

(2013) Ranjith Rajendran et al.   EUKARYOTIC CELL

Extracellular DNA in adhesion and biofilm formation of four environmental isolates: a quantitative study

(2013) Lone Tang et al.   FEMS MICROBIOLOGY ECOLOGY

Effects of extracellular DNA and DNA-binding protein on the development of aStreptococcus intermediusbiofilm

(2013) A. Nur et al.   JOURNAL OF APPLIED MICROBIOLOGY

Self-organization of bacterial biofilms is facilitated by extracellular DNA

(2013) E. S. Gloag et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial natural transformation by highly fragmented and damaged DNA

(2013) S. Overballe-Petersen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extracellular DNA-induced antimicrobial peptide resistance mechanisms in Pseudomonas aeruginosa

(2013) Shawn Lewenza   Frontiers in Microbiology

Functional Specificity of Extracellular Nucleases of Shewanella oneidensis MR-1

(2012) Magnus Heun et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Fratricide Is Essential for Efficient Gene Transfer between Pneumococci in Biofilms

(2012) Hua Wei et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Properties and Biological Role of Streptococcal Fratricins

(2012) Kari Helene Berg et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The cell pole: the site of cross talk between the DNA uptake and genetic recombination machinery

(2012) Dawit Kidane et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Insight into the composition of the intercellular matrix ofStreptococcus pneumoniaebiofilms

(2012) Mirian Domenech et al.   ENVIRONMENTAL MICROBIOLOGY

Biofilm formation by haloarchaea

(2012) Sabrina Fröls et al.   ENVIRONMENTAL MICROBIOLOGY

LytA, Major Autolysin ofStreptococcus pneumoniae, Requires Access to Nascent Peptidoglycan

(2012) Peter Mellroth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Environmental DNA

(2012) PIERRE TABERLET et al.   MOLECULAR ECOLOGY

Natural competence inVibrio choleraeis controlled by a nucleoside scavenging response that requires CytR-dependent anti-activation

(2012) Elena S. Antonova et al.   MOLECULAR MICROBIOLOGY

Extracellular DNA Release by Undomesticated Bacillus subtilis Is Regulated by Early Competence

(2012) Olga Zafra et al.   PLoS One

RecX Facilitates Homologous Recombination by Modulating RecA Activities

(2012) Paula P. Cárdenas et al.   PLoS Genetics

Roles of Two Shewanella oneidensis MR-1 Extracellular Endonucleases

(2011) Julia Gödeke et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

COMPETENCE INCREASES SURVIVAL DURING STRESS IN STREPTOCOCCUS PNEUMONIAE

(2011) Daniel J. P. Engelmoer et al.   EVOLUTION

TheNeisseria gonorrhoeaeBiofilm Matrix Contains DNA, and an Endogenous Nuclease Controls Its Incorporation

(2011) Christopher T. Steichen et al.   INFECTION AND IMMUNITY

LuxS Mediates Iron-Dependent Biofilm Formation, Competence, and Fratricide in Streptococcus pneumoniae

(2011) Claudia Trappetti et al.   INFECTION AND IMMUNITY

Cooperation and cheating in Pseudomonas aeruginosa: the roles of the las, rhl and pqs quorum-sensing systems

(2011) Cara N Wilder et al.   ISME Journal

Role of eDNA on the Adhesion Forces betweenStreptococcus mutansand Substratum Surfaces: Influence of Ionic Strength and Substratum Hydrophobicity

(2011) Theerthankar Das et al.   LANGMUIR

The secretion ATPase ComGA is required for the binding and transport of transforming DNA

(2011) Kenneth Briley Jr et al.   MOLECULAR MICROBIOLOGY

Extracellular nucleases and extracellular DNA play important roles in Vibrio cholerae biofilm formation

(2011) Andrea Seper et al.   MOLECULAR MICROBIOLOGY

Transformation of Natural Genetic Variation into Haemophilus Influenzae Genomes

(2011) Joshua Chang Mell et al.   PLoS Pathogens

The Gonococcal Genetic Island and Type IV Secretion in the Pathogenic Neisseria

(2011) Meghan E. Ramsey et al.   Frontiers in Microbiology

Biofilm formation in Streptococcus pneumoniae

(2011) Mirian Domenech et al.   Microbial Biotechnology

Adsorption of Extracellular Chromosomal DNA and Its Effects on Natural Transformation of Azotobacter vinelandii

(2010) N. Lu et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Role of Extracellular DNA in Initial Bacterial Adhesion and Surface Aggregation

(2010) T. Das et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Role of Extracellular DNA during Biofilm Formation by Listeria monocytogenes

(2010) M. Harmsen et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Pseudomonas aeruginosaproduces an extracellular deoxyribonuclease that is required for utilization of DNA as a nutrient source

(2010) Heidi Mulcahy et al.   ENVIRONMENTAL MICROBIOLOGY

Phage-induced lysis enhances biofilm formation in Shewanella oneidensis MR-1

(2010) Julia Gödeke et al.   ISME Journal

Extracellular DNA in Helicobacter pylori biofilm: a backstairs rumour

(2010) R. Grande et al.   JOURNAL OF APPLIED MICROBIOLOGY

Increased Expression of the Type IV Secretion System in Piliated Neisseria gonorrhoeae Variants

(2010) W. Salgado-Pabon et al.   JOURNAL OF BACTERIOLOGY

A dual role of extracellular DNA during biofilm formation ofNeisseria meningitidis

(2010) Martin Lappann et al.   MOLECULAR MICROBIOLOGY

Pneumococcal CbpD is a murein hydrolase that requires a dual cell envelope binding specificity to kill target cells during fratricide

(2010) Vegard Eldholm et al.   MOLECULAR MICROBIOLOGY

The biofilm matrix

(2010) Hans-Curt Flemming et al.   NATURE REVIEWS MICROBIOLOGY

Prophage Spontaneous Activation Promotes DNA Release Enhancing Biofilm Formation in Streptococcus pneumoniae

(2010) Margarida Carrolo et al.   PLoS One

Beta toxin catalyzes formation of nucleoprotein matrix in staphylococcal biofilms

(2010) M. J. Huseby et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optimal Strategy for Competence Differentiation in Bacteria

(2010) C. Scott Wylie et al.   PLoS Genetics

Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related species

(2010) Claudio Donati et al.   GENOME BIOLOGY

DNA as an Adhesin: Bacillus cereus Requires Extracellular DNA To Form Biofilms

(2009) S. Vilain et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Characterization of extracellular DNA production and flocculation of the marine photosynthetic bacterium Rhodovulum sulfidophilum

(2009) Hiromichi Suzuki et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Characterization of Hydrogen Peroxide-Induced DNA Release by Streptococcus sanguinis and Streptococcus gordonii

(2009) J. Kreth et al.   JOURNAL OF BACTERIOLOGY

Intercellular adhesion and biocide resistance in nontypeable Haemophilus influenzae biofilms

(2009) Era A. Izano et al.   MICROBIAL PATHOGENESIS

Biological Diversity of Prokaryotic Type IV Secretion Systems

(2009) C. E. Alvarez-Martinez et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Fratricide in Streptococcus pneumoniae: contributions and role of the cell wall hydrolases CbpD, LytA and LytC

(2009) V. Eldholm et al.   MICROBIOLOGY-SGM

McsA and B mediate the delocalization of competence proteins from the cell poles of Bacillus subtilis

(2009) Jeanette Hahn et al.   MOLECULAR MICROBIOLOGY

A fratricidal mechanism is responsible for eDNA release and contributes to biofilm development ofEnterococcus faecalis

(2009) Vinai Chittezham Thomas et al.   MOLECULAR MICROBIOLOGY

Cannibalism enhances biofilm development inBacillus subtilis

(2009) Daniel López et al.   MOLECULAR MICROBIOLOGY

Presence of Extracellular DNA in the Candida albicans Biofilm Matrix and its Contribution to Biofilms

(2009) Margarida Martins et al.   MYCOPATHOLOGIA

Modulation of eDNA Release and Degradation Affects Staphylococcus aureus Biofilm Maturation

(2009) Ethan E. Mann et al.   PLoS One

Evidence for Different Pathways during Horizontal Gene Transfer in Competent Bacillus subtilis Cells

(2009) Dawit Kidane et al.   PLoS Genetics

The Population and Evolutionary Dynamics of Homologous Gene Recombination in Bacteria

(2009) Bruce R. Levin et al.   PLoS Genetics

Role of DNA in Bacterial Aggregation

(2008) Hui-Hui Liu et al.   CURRENT MICROBIOLOGY

Roles of type IV pili, flagellum-mediated motility and extracellular DNA in the formation of mature multicellular structures inPseudomonas aeruginosabiofilms

(2008) Kim B. Barken et al.   ENVIRONMENTAL MICROBIOLOGY

Isolation of Streptococcus pneumoniae Biofilm Mutants and Their Characterization during Nasopharyngeal Colonization

(2008) E. J. Munoz-Elias et al.   INFECTION AND IMMUNITY

Regulation of Autolysis-Dependent Extracellular DNA Release by Enterococcus faecalis Extracellular Proteases Influences Biofilm Development

(2008) V. C. Thomas et al.   JOURNAL OF BACTERIOLOGY

Damage and degradation rates of extracellular DNA in marine sediments: implications for the preservation of gene sequences

(2008) C. CORINALDESI et al.   MOLECULAR ECOLOGY

Virus-like vesicles and extracellular DNA produced by hyperthermophilic archaea of the order Thermococcales

(2008) Nicolas Soler et al.   RESEARCH IN MICROBIOLOGY

Ecology and genomics of Bacillus subtilis

(2008) Ashlee M. Earl et al.   TRENDS IN MICROBIOLOGY

Extracellular DNA Chelates Cations and Induces Antibiotic Resistance in Pseudomonas aeruginosa Biofilms

(2008) Heidi Mulcahy et al.   PLoS Pathogens