Advantages of the Silkworm As an Animal Model for Developing Novel Antimicrobial Agents

Synergistic effects of vancomycin and β-lactams against vancomycin highly resistant Staphylococcus aureus

(2017) Fumiaki Tabuchi et al.   JOURNAL OF ANTIBIOTICS

Lysobacter species: a potential source of novel antibiotics

(2016) Suresh Panthee et al.   ARCHIVES OF MICROBIOLOGY

Precise genome editing in the silkworm Bombyx mori using TALENs and ds- and ssDNA donors – A practical approach

(2016) Yoko Takasu et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

ASP2397: a novel antifungal agent produced by Acremonium persicinum MF-347833

(2016) Ikuko Nakamura et al.   JOURNAL OF ANTIBIOTICS

Discovery of a new antifungal agent ASP2397 using a silkworm model of Aspergillus fumigatus infection

(2016) Ikuko Nakamura et al.   JOURNAL OF ANTIBIOTICS

In silico identification of lysocin biosynthetic gene cluster from Lysobacter sp. RH2180-5

(2016) Suresh Panthee et al.   JOURNAL OF ANTIBIOTICS

A silkworm infection model to investigate Vibrio vulnificus virulence genes

(2016) Mai Yamamoto et al.   Molecular Medicine Reports

In VitroActivity of ASP2397 against Aspergillus Isolates with or without Acquired Azole Resistance Mechanisms

(2015) Maiken Cavling Arendrup et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Advanced technologies for genetically manipulating the silkwormBombyx mori, a model Lepidopteran insect

(2015) Hanfu Xu et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Phenotypic and genomic comparisons of highly vancomycin-resistant Staphylococcus aureus strains developed from multiple clinical MRSA strains by in vitro mutagenesis

(2015) Kenichi Ishii et al.   Scientific Reports

Fluorescence imaging for a noninvasive in vivo toxicity-test using a transgenic silkworm expressing green fluorescent protein

(2015) Yoshinori Inagaki et al.   Scientific Reports

Targeted disruption of a single sex pheromone receptor gene completely abolishes in vivo pheromone response in the silkmoth

(2015) Takeshi Sakurai et al.   Scientific Reports

PARALYTIC PEPTIDE: AN INSECT CYTOKINE THAT MEDIATES INNATE IMMUNITY

(2014) Kenichi Ishii et al.   ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY

Lysocin E is a new antibiotic that targets menaquinone in the bacterial membrane

(2014) Hiroshi Hamamoto et al.   Nature Chemical Biology

Structure–activity relationship study of novel iminothiadiazolo-pyrimidinone antimicrobial agents

(2013) Atmika Paudel et al.   JOURNAL OF ANTIBIOTICS

Insect cytokine paralytic peptide activates innate immunity via nitric oxide production in the silkworm Bombyx mori

(2012) Kenichi Ishii et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Evaluation of Staphylococcus aureus virulence factors using a silkworm model

(2011) Shinya Miyazaki et al.   FEMS MICROBIOLOGY LETTERS

Identification of novel deoxyribofuranosyl indole antimicrobial agents

(2011) Atmika Paudel et al.   JOURNAL OF ANTIBIOTICS

Quantitative evaluation of cryptococcal pathogenesis and antifungal drugs using a silkworm infection model with Cryptococcus neoformans

(2011) Y. Matsumoto et al.   JOURNAL OF APPLIED MICROBIOLOGY

Nosokomycins, new antibiotics discovered in an in vivo-mimic infection model using silkworm larvae. I: Fermentation, isolation and biological properties

(2010) Ryuji Uchida et al.   JOURNAL OF ANTIBIOTICS

Evaluation of Target Specificity of Antibacterial Agents Using Staphylococcus aureus ddlA Mutants and D-Cycloserine in a Silkworm Infection Model

(2009) K. Kurokawa et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Silkworm expression system as a platform technology in life science

(2009) Tatsuya Kato et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Silkworm as a model animal to evaluate drug candidate toxicity and metabolism

(2008) Hiroshi Hamamoto et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

The genome of a lepidopteran model insect, the silkworm Bombyx mori

(2008) The International Silkworm Genome   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY