Article
Plant Sciences
Long Lin, Zixiang Yang, Min Tao, Danyu Shen, Chuanbin Cui, Pingping Wang, Limin Wang, Maofeng Jing, Guoliang Qian, Xiaolong Shao
Summary: This study demonstrated that OH11 could prevent plant infection by Phytophthora pathogens through multiple mechanisms, making it a promising alternative resource for promoting plant resistance to multiple Phytophthora pathogens.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Agriculture, Multidisciplinary
Amanda Lynn Miller, Shanren Li, Catherine D. Eichhorn, Yongbiao Zheng, Liangcheng Du
Summary: In this study, the first siderophore, lysochelin, and its biosynthetic gene cluster were identified from Lysobacter enzymogenes. It was found that lysochelin, along with antifungal compounds HSAF and its analogues, are crucial for the disease control activity and survival of Lysobacter under oxidative stresses caused by excess iron. The production of these molecules is greatly affected by iron concentration.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Agriculture, Multidisciplinary
Rongxian Hou, Kaihuai Li, Baodian Guo, Yangyang Zhao, Chaohui Li, Bao Tang, Weibo Sun, Bo Wang, Wenchan Chen, Cong Sheng, Jialiang Kan, Yancun Zhao, Fengquan Liu
Summary: This study identified the potential target of heat-stable antifungal factor (HSAF) in fungi and found that HSAF binds to specific sites on VpVeb1, resulting in decreased virulence of V. pyri.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Chemistry, Organic
Huan Yue, Liangcheng Du
Summary: This study reveals the important role of hsaf-orf1 in the regulation and biosynthesis of HSAF and its analogs by controlling the import of sugars, which induce antifungal production.
Article
Plant Sciences
Kaihuai Li, Rongxian Hou, Xue Zhou, Chunlan Xiong, Cheng Li, Yong Wang, Fengquan Liu
Summary: In this study, a potential regulator of HSAF biosynthesis, RecX, was identified. Deletion of recX increased HSAF production, while overexpression of recX suppressed HSAF production. It was found that RecX directly binds to the promoter region of the lafB gene to inhibit its transcription and thus decrease HSAF production in L. enzymogenes.
PHYTOPATHOLOGY RESEARCH
(2023)
Article
Microbiology
Sonia Martinez-Servat, Lola Pinyol-Escala, Oriol Daura-Pich, Marta Almazan, Iker Hernandez, Belen Lopez-Garcia, Carolina Fernandez
Summary: This paper describes the efficacy of Lysobacter enzymogenes B25 as a biological control agent against root-knot nematodes in tomato plants. The study investigates the mode of action of B25, which involves motility, production of lytic enzymes and secondary metabolites, and induction of plant defenses. The findings suggest that L. enzymogenes B25 has potential as a sustainable biocontrol microorganism against nematode infestation.
Review
Biochemistry & Molecular Biology
Kangwen Xu, Long Lin, Danyu Shen, Shan-Ho Chou, Guoliang Qian
Summary: The review summarizes the mechanisms through which Clp, a CRP-like protein, initiates a mobile-attack strategy in Lysobacter enzymogenes against fungal pathogens, including binding to DNA in a unique pattern, interacting directly with small molecules or responding to them, and specific interactions with proteins adopting distinct structures.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL
(2021)
Article
Multidisciplinary Sciences
Ghadeer A. R. Y. Suaifan, Diana M. A. B. Abdel Rahman, Ala' M. M. Abu-Odeh, Fahid Abu Jbara, Mayadah Shehadeh, Rula Darwish
Summary: Combining Lysobacter enzymogenes bioactive proteases in the cell-free supernatant with cefixime, levofloxacin, and gentamicin has shown significant growth inhibition against MSSA and MRSA. Furthermore, combining L. enzymogenes CFS with cefixime can restore its antibacterial activity against MRSA at sub-minimal inhibitory concentration levels.
Article
Microbiology
Xi Shen, Bingxin Wang, Nianda Yang, Lulu Zhang, Danyu Shen, Huijun Wu, Ying Dong, Ben Niu, Shan-Ho Chou, Gerardo Puopolo, Jiaqin Fan, Guoliang Qian
Summary: The study revealed that the soilborne biocontrol bacterium Lysobacter enzymogenes OH11 uses T4SS as the main contact-dependent weapon against other soilborne bacteria, decreasing their activity while protecting carrots from infection. This highlights the crucial role of T4SS in the killing behavior of L. enzymogenes and its impact on interactions in the soil microbiome.
ENVIRONMENTAL MICROBIOLOGY
(2021)
Article
Agriculture, Multidisciplinary
Hongjun Yang, Liyuan Peng, Zhimo Li, Chunyang Huang, Jianguo Huang
Summary: A study found that the biocontrol bacterium Lysobacter enzymogenes (CQ18) and its metabolite L-pyroglutamate can effectively control tobacco powdery mildew, with advantages of safety, environmental friendliness, and low cost.
CHEMICAL AND BIOLOGICAL TECHNOLOGIES IN AGRICULTURE
(2023)
Article
Microbiology
Faranak Faraji Tabar, Vahideh Valizadeh, Malihe Keramati, Maryam Davoudi, Sara Molasalehi, Neda Shabani Fakhabi, Seyed Mohammad Atyabi, Reza Ahangari Cohan, Dariush Norouzian
Summary: In this study, cold atmospheric plasma (CAP) was used to induce mutagenesis in L. enzymogenes bacteria and mutant strains with enhanced proteolytic activity were obtained through screening. The purification process and gene sequences of the mutants were analyzed to understand the molecular aspects of CAP mutagenesis. The results highlight the significance of this method for obtaining industrial strains.
ARCHIVES OF MICROBIOLOGY
(2022)
Article
Physics, Multidisciplinary
O. J. Meacock, A. Doostmohammadi, K. R. Foster, J. M. Yeomans, W. M. Durham
Summary: The study demonstrates that slow movement of Pseudomonas aeruginosa is vital for its collective migration across surfaces, as it avoids being trapped by topological defects resulting from faster cell movements. In contrast, faster mutant cells are overtaken and outcompeted by slower wild-type cells at high cell densities, leading to faster collective behavior and migration. The physics of liquid crystals helps explain how bacteria can outcompete each other in the race for new territory by generating topological defects that trap fast-moving cells.
Article
Agricultural Engineering
Bao Tang, Xian Chen, Pedro Laborda, Fengquan Liu
Summary: The study successfully developed a method using macroporous adsorption resins to separate Alteramide B (ATB), resulting in a significant increase in ATB content in a short period of time with a high recovery yield. This method is simple, efficient, and economical.
BIORESOURCE TECHNOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Menghao Yu, Youfu Zhao
Summary: Deletion of the CsrA gene in Lysobacter enzymogenes strain C3 resulted in slow growth and reduced resistance to multiple antibiotics. The deletion also affected its ability to inhibit hypha growth and its extracellular enzyme activities. Additionally, two putative small noncoding regulatory RNAs (sRNAs), csrB and csrC, were identified in the genome of LeC3. Double deletion of csrB and csrC increased resistance to antibiotics but did not affect biocontrol activity.
JOURNAL OF APPLIED MICROBIOLOGY
(2023)
Article
Plant Sciences
Shaima M. N. Moustafa, Rania H. Taha
Summary: The study utilized a biosynthesis-green method to prepare a Zn(II) complex as an antifungal agent, evaluating its effectiveness for growth promotion of Vicia feba and inhibitory activity against Pythium aphanidermatum. The results showed significant inhibition of pathogenic fungus growth and improved biomass of Vicia faba, with positive effects on root and shoot weight and length, as well as germination percentage. Further research should focus on utilizing biogenic Zinc nano-complex as plant growth promoter agents to enhance seed germination and overall plant health.
Article
Chemistry, Multidisciplinary
Wei Liu, Shi-ou Zhu, Yu-lin Guo, Long-fang Tu, Yong-qi Zhen, Rong-yan Zhao, Liang Ou-Yang, Hiroshi Kurihara, Rong-Rong He, Bo Liu
Summary: Amyotrophic lateral sclerosis (ALS) is a common fatal neurodegenerative disease. The ULK1 activator BL-918 has shown therapeutic potential in treating ALS by inducing cytoprotective autophagy. This study provides further evidence of autophagic dysfunction in ALS pathogenesis.
ACTA PHARMACOLOGICA SINICA
(2023)
Article
Chemistry, Multidisciplinary
Jian Li, Jina Sun, Xianglei Zhang, Ruxue Zhang, Qian Wang, Lin Wang, Leike Zhang, Xiong Xie, Chunpu Li, Yu Zhou, Jiang Wang, Gengfu Xiao, Fang Bai, Hong Liu
Summary: This study reports a highly efficient and practical method for the functionalization and macrocyclization of Trp and Trp-containing peptides. The resulting macrocycles showed promising anti-SARS-CoV-2 activities through binding with the N protein of the virus, indicating their potential as antiviral agents.
CHEMICAL COMMUNICATIONS
(2023)
Article
Engineering, Environmental
Ying Ma, Hao Wang, Qiqi Wang, Xiaodong Cao, Huichang Gao
Summary: This study developed a multi-channel nerve guidance conduit (NGC) with dual electrical activity of piezoelectricity and conductivity to enhance peripheral nerve regeneration. In vitro and in vivo experiments demonstrated that the electroactive NGC promoted cell proliferation, differentiation, axonal regeneration, and functional recovery of peripheral nerves, indicating its great potential in repairing peripheral nerve injuries.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Computer Science, Software Engineering
Xiaoxiao Liu, Mohammad S. Alharbi, Jian Chen, Alexandra Diehl, Dylan Rees, Elif E. Firat, Qiru Wang, Robert S. Laramee
Summary: Visualization is a rapidly growing field that is important for researchers, practitioners, and higher educational institutions. This paper presents a survey of open visualization resources for those interested in interactive data visualization and visual analytics. The paper provides a classification of resource collections, allowing individuals from different backgrounds to find useful and detailed information.
INFORMATION VISUALIZATION
(2023)
Article
Chemistry, Physical
Shulin Dong, Yingdong Qu, Ruirun Chen, Guanglong Li, Wei Zhang, Qi Wang, Hongze Fang, Jingjie Guo, Bo Yu
Summary: By designing and preparing Ti-44Al-4Nb-0.5Fe-0.1B and Ti-44Al-2Nb-2Fe-0.1B alloys, the study focuses on whether and why the hot deformation processing capability of the new alloys is improved. The results show that the Ti-44Al-2Nb-2Fe-0.1B alloy has lower true stress, moderate diffusion activation energy, lower stress exponent, larger hot processing window, lower dislocation density, and more adequate dynamic recrystallization, demonstrating its good hot deformation processing capability and service properties.
Article
Ecology
Shuying Yu, Xuesong Kong, Qi Wang, Zhiwei Yang, Jian Peng
Summary: This study quantitatively assessed flood resilience in the Dongting Lake Basin using a process-based evaluation framework. The results showed that the overall resilience of the basin was high, but the flood resilience in the Dongting Lake Eco-economic Zone was poor. The synergy of robustness and resistance dominated flood resilience, providing a new process perspective for improving it.
LANDSCAPE AND URBAN PLANNING
(2023)
Article
Engineering, Chemical
Yuefa Jia, Hongru Han, Yi Luo, Qizhao Wang, Bo Wha Lee, Chunli Liu
Summary: In this study, Z-scheme ZnFe2O4-SrTiO3 nanocomposite was prepared and used for tetracycline hydrochloride (TCH) degradation and CO2 conversion. The nanocomposite showed significantly higher TCH degradation efficiency and CO2 photoreduction activity compared to pure ZnFe2O4 and SrTiO3. The enhanced activities were attributed to improved solar energy utilization and efficient electron-hole pair separation through a Z-scheme charge transfer model. The results suggest that ZnFe2O4-SrTiO3 nanocomposite has great potential for wastewater purification and CO2 reduction to renewable solar fuels.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Article
Nanoscience & Nanotechnology
Xuran Zhang, Mingjin Dai, Wenjie Deng, Yongzhe Zhang, Qi Jie Wang
Summary: A PdSe2 photodetector with asymmetric van der Waals contacts is reported, achieving a high responsivity, fast rise/decay times, and a high detectivity in the visible-near infrared range. The device also shows linear polarization-sensitive response and outstanding polarization imaging capabilities. This PdSe2-based photodetector has great potential for high-performance applications without external bias.
Article
Orthopedics
Fei Guo, Shuaiying Jia, Qiyan Wang, Qinyu Liu, Mingquan Hu, Wenzhang Wang, Shijian Liu, Qiang Li, Bin Lu, Yeying Zheng
Summary: Patients with hypertension undergoing prone spine surgery are at risk of developing POCD, and intraoperative SstO2 is associated with POCD, while SctO2 shows no association with POCD.
ORTHOPAEDIC SURGERY
(2023)
Article
Chemistry, Physical
Qibin Wang, Qi Wang, Ruirun Chen, Xiaowei Wang, Yanqing Su, Hengzhi Fu
Summary: The effects of Fe and C on the microstructural evolution, properties, and hot deformation behavior of Nb-24Ti-16Si-2Al-3V-xFe-yC alloys were investigated. The results show that the microstructure of the alloys changes with the Fe and C content, and Fe and C have synergistic effects on the properties and hot deformation behavior of the alloys.
JOURNAL OF ALLOYS AND COMPOUNDS
(2023)
Article
Biochemical Research Methods
Dongfang Li, Manli Zhao, Chao Tao, Xiaoqin Qian, Xiaojun Liu
Summary: Microcirculation imaging plays a significant role in the early diagnosis and assessment of various diseases. In this study, an optical-resolution photoacoustic microscopy (OR-PAM) was used to image the microvasculature of the nailbed. The sensitivity of imaging was significantly improved by hydrating the nail. In vivo experiments further demonstrated the enhanced sensitivity and practicality of OR-PAM, while the quantitative analysis of capillary loops provided valuable indicators for clinical microcirculation detection using OR-PAM.
JOURNAL OF BIOPHOTONICS
(2023)
Article
Integrative & Complementary Medicine
ShiJie Su, Gongcan Chen, Minghuang Gao, Guangcheng Zhong, Zerong Zhang, Dongyun Wei, Xue Luo, Qi Wang
Summary: The study aimed to investigate the effects of Kai-Xin-San (KXS) on cognitive deficits in APP/PS1 mice and its neuroprotective mechanism. The results showed that KXS protected APP/PS1 mice from cognitive impairments, suppressed neuronal apoptosis and oxidative stress, and improved mitochondrial dysfunction and synaptic and neurotrophic factors. Additionally, KXS enhanced mitochondrial SIRT3 expression and reduced NLRP3 inflammasome expression in APP/PS1 mice. These findings suggest that KXS could be a potential neuroprotective agent for Alzheimer's disease progression.
Article
Oncology
Qijun Wang, Zhewei Shen, Mengxi Ge, Jie Xu, Xin Zhang, Wei Zhu, Jie Liu, Wei Hua, Ying Mao
Summary: This case report describes a 46-year-old male patient with PD-L1 negative brain metastases (BrMs) 12 years after gastric cancer resection and chemotherapy. Treatment with the immune checkpoint inhibitor pembrolizumab resulted in a complete response of all metastatic tumors. A durable remission of the tumors was observed after 4 years of follow-up. The need for a therapeutic protocol for late-stage gastric cancer with BrMs and the exploration of biomarkers other than PD-L1 expression to predict the efficacy of immune checkpoint inhibitors were emphasized.
FRONTIERS IN ONCOLOGY
(2023)
Article
Plant Sciences
Kaihuai Li, Rongxian Hou, Xue Zhou, Chunlan Xiong, Cheng Li, Yong Wang, Fengquan Liu
Summary: In this study, a potential regulator of HSAF biosynthesis, RecX, was identified. Deletion of recX increased HSAF production, while overexpression of recX suppressed HSAF production. It was found that RecX directly binds to the promoter region of the lafB gene to inhibit its transcription and thus decrease HSAF production in L. enzymogenes.
PHYTOPATHOLOGY RESEARCH
(2023)
Article
Chemistry, Physical
Ziqiang Wang, Guanghui Yang, Pengjun Tian, Kai Deng, Hongjie Yu, You Xu, Xiaonian Li, Hongjing Wang, Liang Wang
Summary: In this study, we propose a method to encapsulate rhodium nanoparticles (NPs) on a palladium metallene film using a bromine initiator for catalyzing both the oxidation and reduction reactions. The Rh/Pd film exhibits excellent hydrogen evolution and hydrazine catalytic activities due to its abundant active sites and rapid charge transfer rate. In the hydrazine-assisted water splitting system, the Rh/Pd film only requires a low overpotential to produce hydrogen.
JOURNAL OF MATERIALS CHEMISTRY A
(2023)