Dietary Heme Induces Gut Dysbiosis, Aggravates Colitis, and Potentiates the Development of Adenomas in Mice

Iron Supplements Modulate Colon Microbiota Composition and Potentiate the Protective Effects of Probiotics in Dextran Sodium Sulfate-induced Colitis

(2017) Marco Constante et al.   INFLAMMATORY BOWEL DISEASES

Fecal neutrophil gelatinase-associated lipocalin as a biomarker for inflammatory bowel disease

(2017) Silje Thorsvik et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Microbiome and colorectal cancer: Unraveling host-microbiota interactions in colitis-associated colorectal cancer development

(2017) Mingsong Kang et al.   SEMINARS IN IMMUNOLOGY

Sodium Butyrate Reduces Colitogenic Immunoglobulin A-Coated Bacteria and Modifies the Composition of Microbiota in IL-10 Deficient Mice

(2016) Tenghui Zhang et al.   Nutrients

High Fat Diets Induce Colonic Epithelial Cell Stress and Inflammation that is Reversed by IL-22

(2016) Max Gulhane et al.   Scientific Reports

The gut microbiota in conventional and serrated precursors of colorectal cancer

(2016) Brandilyn A. Peters et al.   Microbiome

An isotope-labeled chemical derivatization method for the quantitation of short-chain fatty acids in human feces by liquid chromatography–tandem mass spectrometry

(2015) Jun Han et al.   ANALYTICA CHIMICA ACTA

Diet Dominates Host Genotype in Shaping the Murine Gut Microbiota

(2015) Rachel N. Carmody et al.   Cell Host & Microbe

Gut microbiota facilitates dietary heme-induced epithelial hyperproliferation by opening the mucus barrier in colon

(2015) Noortje Ijssennagger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Meta-analyses of human gut microbes associated with obesity and IBD

(2014) William A. Walters et al.   FEBS LETTERS

Heme Oxygenase-1 Ameliorates Dextran Sulfate Sodium-induced Acute Murine Colitis by Regulating Th17/Treg Cell Balance

(2014) Liya Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Colorectal cancer in inflammatory bowel disease: The risk, pathogenesis, prevention and diagnosis

(2014) Eun Ran Kim   WORLD JOURNAL OF GASTROENTEROLOGY

Transition metal ions at the crossroads of mucosal immunity and microbial pathogenesis

(2014) Vladimir E. Diaz-Ochoa et al.   Frontiers in Cellular and Infection Microbiology

PEAR: a fast and accurate Illumina Paired-End reAd mergeR

(2013) J. Zhang et al.   BIOINFORMATICS

Gut Microbiota Protects against Gastrointestinal Tumorigenesis Caused by Epithelial Injury

(2013) Y. Zhan et al.   CANCER RESEARCH

Dietary heme induces acute oxidative stress, but delayed cytotoxicity and compensatory hyperproliferation in mouse colon

(2013) N. Ijssennagger et al.   CARCINOGENESIS

Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences

(2013) Morgan G I Langille et al.   NATURE BIOTECHNOLOGY

Control of pathogens and pathobionts by the gut microbiota

(2013) Nobuhiko Kamada et al.   NATURE IMMUNOLOGY

Review of the association between meat consumption and risk of colorectal cancer

(2013) Eunjung Kim et al.   NUTRITION RESEARCH

Processed meat consumption and risk of cancer: a multisite case–control study in Uruguay

(2012) E De Stefani et al.   BRITISH JOURNAL OF CANCER

Bacterial Cell Wall Constituents Induce Hepcidin Expression in Macrophages Through MyD88 Signaling

(2012) Antonio Layoun et al.   INFLAMMATION

Westernized high-fat diet accelerates weight loss in dextran sulfate sodium-induced colitis in mice, which is further aggravated by supplementation of heme

(2012) Elise M.J. van der Logt et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10 −/− mice

(2012) Suzanne Devkota et al.   NATURE

The gut microbiota in IBD

(2012) Chaysavanh Manichanh et al.   Nature Reviews Gastroenterology & Hepatology

High Fat Diet-Induced Gut Microbiota Exacerbates Inflammation and Obesity in Mice via the TLR4 Signaling Pathway

(2012) Kyung-Ah Kim et al.   PLoS One

Dietary Heme Alters Microbiota and Mucosa of Mouse Colon without Functional Changes in Host-Microbe Cross-Talk

(2012) Noortje IJssennagger et al.   PLoS One

Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota

(2012) J. C. Arthur et al.   SCIENCE

Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment

(2012) Xochitl C Morgan et al.   GENOME BIOLOGY

Effects of diet-induced obesity on colitis-associated colon tumor formation in A/J mice

(2011) S-Y Park et al.   INTERNATIONAL JOURNAL OF OBESITY

Inflammation and Colon Cancer

(2010) Janoš Terzić et al.   GASTROENTEROLOGY

Overcoming the Heme Paradox: Heme Toxicity and Tolerance in Bacterial Pathogens

(2010) L. L. Anzaldi et al.   INFECTION AND IMMUNITY

Heme induces DNA damage and hyperproliferation of colonic epithelial cellsviahydrogen peroxide produced by heme oxygenase: A possible mechanism of heme-induced colon cancer

(2010) Shin-ichi Ishikawa et al.   MOLECULAR NUTRITION & FOOD RESEARCH

QIIME allows analysis of high-throughput community sequencing data

(2010) J Gregory Caporaso et al.   NATURE METHODS

Dietary heme adversely affects experimental colitis in rats, despite heat-shock protein induction

(2010) Marloes A.A. Schepens et al.   NUTRITION

Meat Intake and Mortality

(2009) Rashmi Sinha et al.   ARCHIVES OF INTERNAL MEDICINE

Contribution of STAT3 and SMAD4 pathways to the regulation of hepcidin by opposing stimuli

(2009) H. Huang et al.   BLOOD

Association of Inflammation-Related and microRNA Gene Expression with Cancer-Specific Mortality of Colon Adenocarcinoma

(2009) A. J. Schetter et al.   CLINICAL CANCER RESEARCH

Bacterial heme-transport proteins and their heme-coordination modes

(2008) Yong Tong et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Iron availability and infection

(2008) Eugene D. Weinberg   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Reduced Colitis-Associated Colon Cancer in Fat-1 (n-3 Fatty Acid Desaturase) Transgenic Mice

(2008) Q. Jia et al.   CANCER RESEARCH

Metagenomic Approaches for Defining the Pathogenesis of Inflammatory Bowel Diseases

(2008) Daniel A. Peterson et al.   Cell Host & Microbe

Microbial Influences in Inflammatory Bowel Diseases

(2008) R. Balfour Sartor   GASTROENTEROLOGY