Article
Cell Biology
Hui Liu, Chen Bai, Fuyang Xian, Shaoyang Liu, Chaojun Long, Li Hu, Tiegang Liu, Xiaohong Gu
Summary: This study found that a high-calorie diet and LPS atomization synergistically aggravated lung inflammation injury in juvenile rats. The high-calorie diet disrupted the balance of Th17/Treg cells and changed the composition and abundance of the gut microbiome. These findings provide a new perspective on the pathogenesis of lung inflammation injury and suggest a potential microbiota-targeting therapy for inflammatory lung diseases.
JOURNAL OF LEUKOCYTE BIOLOGY
(2022)
Article
Nutrition & Dietetics
Siqi Yao, Yiming Zhao, Hao Chen, Ruizheng Sun, Liyu Chen, Jing Huang, Zheng Yu, Shuijiao Chen
Summary: Dietary habits can alter the composition of gut microbiota, and exploring the impact of nutritional patterns on gut microbiota changes can help protect gut health.
Article
Nutrition & Dietetics
Liuqiao Sun, Xuying Tan, Xiaoping Liang, Hangjun Chen, Qian Ou, Qiongmei Wu, Xinxue Yu, Hanqing Zhao, Qiaoli Huang, Zehua Yi, Jun Wei, Feng Wu, Huilian Zhu, Lijun Wang
Summary: Maternal betaine supplementation alleviates NAFLD in offspring through regulating gut microbiota and SCFAs.
Review
Food Science & Technology
Jie Cai, Zhongxu Chen, Wei Wu, Qinlu Lin, Ying Liang
Summary: The role of intestinal flora in health and disease is a hot research topic. High-protein diets (HPDs) may increase the risk of certain diseases, particularly with long-term consumption. Short-term HPDs have minimal impact on healthy individuals under 65 but may be more challenging for those over 65 to meet protein needs.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Agriculture, Multidisciplinary
Jianhui Liu, Huafang Ding, Chi Yan, Zouyan He, Hanyue Zhu, Ka Ying Ma
Summary: The aim of this study was to explore the underlying mechanisms linking the intestinal microbiota and anti-obesity benefits of green tea, oolong tea, and black tea catechins. The results showed that the three tea catechins significantly alleviated obesity and low-grade inflammation, prevented hepatic steatosis, and upregulated the expression of hepatic peroxisome proliferator-activated receptor alpha (PPAR alpha). Metagenomic analysis indicated that the three tea catechins similarly changed the microbiota in terms of overall structure, composition, and protein functions by regulating metabolites and repressing lipopolysaccharides. Therefore, the anti-obese properties of tea catechins were partially mediated by their effects on gut microbiota, hepatic steatosis alleviation, and anti-inflammatory activity.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Food Science & Technology
Bo Qiao, Jing Liu, Xinxin Peng, Ying Cai, Maijiao Peng, Xiaoya Li, Zhoujin Tan, Na Deng
Summary: Preliminary research suggests that a high-fat diet in a fatigued state can trigger diarrhea, but the exact mechanism is unclear. This study investigates the composition and metabolomics of the gut microbiota to understand the pathogenesis of diarrhea. The results show that an HFD in a fatigued state causes changes in gut microbiota, deprivation of short-chain fatty acids, increased inflammation, and dysregulated lipid metabolism, all of which may contribute to the development of diarrhea.
MOLECULAR NUTRITION & FOOD RESEARCH
(2023)
Article
Microbiology
Gang He, Tangcong Chen, Lifen Huang, Yiyuan Zhang, Yanjiao Feng, Shaokui Qu, Xiaojing Yin, Li Liang, Jun Yan, Wei Liu
Summary: This study found that Tremella fuciformis polysaccharide (TP) can inhibit high-fat diet-induced obesity by modulating inflammation and the microbe-gut-brain axis, improving gut microbiota disorders and reducing fat accumulation and abnormal blood glucose and lipid levels.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Yu Li, Daiyang Xia, Jianying Chen, Xiufen Zhang, Heng Wang, Liang Huang, Jiajia Shen, Shunxiang Wang, Yan Feng, Danyan He, Jiaqing Wang, Hui Ye, Yongwen Zhu, Lin Yang, Wence Wang
Summary: Dietary fiber plays a crucial role in gastrointestinal health and its effect on goose growth and lipid levels varies with different viscosities. High viscosity fiber has a better lipid-lowering effect, while medium viscosity fiber provides better intestinal mucosal protection.
Article
Food Science & Technology
Ting Wu, Mingyue Shen, Qiang Yu, Yi Chen, Xianxiang Chen, Jun Yang, Lixin Huang, Xiaomei Guo, Jianhua Xie
Summary: The study revealed that Cyclocarya paliurus polysaccharide has an impact on the gut microbiota of healthy mice, increasing the release of short-chain fatty acids, enhancing microbial diversity, and affecting the relative abundance of specific bacteria.
FOOD RESEARCH INTERNATIONAL
(2021)
Article
Microbiology
Jin Jin, Jiani Wang, Ruyue Cheng, Yan Ren, Zhonghua Miao, Yating Luo, Qingqing Zhou, Yigui Xue, Xi Shen, Fang He, Haoming Tian
Summary: This study aimed to evaluate the possible anti-obesity effects of orlistat and ezetimibe and determine the mechanism by which they alter the composition of gut microbiota and short-chain fatty acids (SCFAs) in mice with a high-fat diet (HFD)-induced obesity. The administration of orlistat and ezetimibe can characteristically influence the body weight and serum lipid metabolism, and glucolipid levels in diet-induced obese mice and is accompanied by significant changes in the gut microbiota and SCFAs.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Immunology
Na Wu, Jingwei Zhou, Heng Mo, Qing Mu, Huiting Su, Mei Li, Yimeng Yu, Aiyu Liu, Qi Zhang, Jun Xu, Weidong Yu, Peng Liu, Guoli Liu
Summary: This study analyzed the gut microbiota composition of 27 GDM and 30 healthy subjects, identifying specific bacteria associated with GDM, blood glucose levels, and obesity. The study also found that short-term diet management in GDM is associated with changes in specific bacteria, rather than an alternative gut microbial pattern. These findings have important implications for understanding the effects of diet intervention on the gut microbiota and metabolism in pregnant women with GDM.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Nutrition & Dietetics
Yapeng Li, Lei Ren, Yunyi Wang, Jinxing Li, Qingqing Zhou, Chenrui Peng, Yuchen Li, Ruyue Cheng, Fang He, Xi Shen
Summary: Evidence suggests a relationship between breast milk microbiota and infant gut microbiota. This study aimed to compare the effects of breast milk microbiota on the construction and colonization of gut microbiota in newborns. It was found that breast milk microbiota partially influences the construction of infant gut microbiota, with key strains such as Lactobacillus, Bifidobacterium, and Enterobacter having a crucial influence. However, this influence is not through direct strain transmission but may be mediated by the cross-feeding effect of short-chain fatty acids.
Article
Endocrinology & Metabolism
Li Wang, Hao Xu, Bin Tan, Qin Yi, Huiwen Liu, Hongrong Deng, Yunxia Chen, Rui Wang, Jie Tian, Jing Zhu
Summary: The gut microbiota and its derived short-chain fatty acids (SCFAs) can reverse obesity-induced precocious puberty by regulating the hypothalamic-pituitary-gonadal axis (HPGA) through the Kiss1-GPR54-PKC-ERK1/2 pathway.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Review
Immunology
Xiaokang Jia, Wen Xu, Lei Zhang, Xiaoyan Li, Ruirui Wang, Shuisheng Wu
Summary: Hyperlipidemia, characterized by excess fat or lipids in the bloodstream, is a high-risk factor for metabolic diseases. The gut microbiota and microbiota-related metabolites play crucial roles in the development and progression of hyperlipidemia. Various interventions targeted at the gut microbiota, such as prebiotics, probiotics, and fecal microbiota transplantation, have shown efficacy in treating hyperlipidemia.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Nutrition & Dietetics
Joanna Szurkowska, Jakub Wiacek, Konstantinos Laparidis, Joanna Karolkiewicz
Summary: Bodybuilders consume more protein but show no significant difference in selected intestinal bacteria counts compared to sedentary individuals; this may be due to both groups having appropriate fiber intake.
Article
Microbiology
Fan Xiong, Sijia Chen, Ivan Jakovlic, Wenxiang Li, Ming Li, Hong Zou, Guitang Wang, Shangong Wu
Summary: This study found that the bile acid profile, especially secondary bile acids, underwent significant changes when grass carp and mice were fed with Citrobacter freundii. Additionally, lipid metabolism was significantly affected by C. freundii. Analysis of liver transcriptome sequencing data revealed that the CYP7A1 gene was significantly up-regulated in both grass carp and mice. Overexpression of HNF4B in grass carp resulted in a significant increase in the expression level of CYP7A1. These findings suggest that intestinal microbiota play a conserved role in bile acid metabolism in vertebrates, and HNF4B may be an important regulator of bile acid metabolism in fish.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Biotechnology & Applied Microbiology
Hong Zou, Fang-Lin Chen, Wen-Xiang Li, Ming Li, Hong-Peng Lei, Dong Zhang, Ivan Jakovlic, Gui-Tang Wang
Summary: The mitochondrial genome structure of the earliest-branching Enoplea lineages in the phylum Nematoda, such as Trichinellida, is relatively conserved, while lineages like Dorylaimida and Mermithida exhibit rapidly evolving architecture. In Enoplea, Pseudocapillaria tomentosa displayed unique base composition and highly reduced noncoding regions. Lineages with reduced/inverted skews, such as Mermithidae, suggest inversions in the strand replication order or disrupted replication mechanism.
Article
Environmental Sciences
Xiaoqin Xiong, Qingchao Shi, Hao Liu, Qian Zhou, Huatao Li, Peng Hu, Zhengyong Wen, Jianwei Wang, Yuanchao Zou, Yu Zeng, Yaotong Hao
Summary: This study investigated the toxic effects of mercury on different life stages of rare minnow and determined the safe level of exposure. The findings showed that newly hatched larvae were the most sensitive to mercury toxicity, while embryos were the most resistant.
Article
Environmental Sciences
Yaotong Hao, Yanfeng Sun, Mo Li, Xuedan Fang, Zhikui Wang, Jiulong Zuo, Cuiyun Zhang
Summary: This study investigates the potential toxic effects of different sizes and concentrations of polystyrene microplastics on grass carp, and finds that the toxic effects are dependent on the size and concentration of microplastics. Exposure to microplastics leads to decreased growth rate, increased intestinal damage, and oxidative stress in the fish. Microplastics also significantly alter the composition of the fish's intestinal microbiome. Furthermore, a 7-day depuration period is not sufficient for complete normalization.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Biochemistry & Molecular Biology
Md. Akibul Hasan Bakky, Ngoc Tuan Tran, Ming Zhang, Yongsheng Zhang, Huifen Liang, Yilei Wang, Yueling Zhang, Hongyu Ma, Huaiping Zheng, Shengkang Li
Summary: This study characterized the polysaccharide from Gracilaria lemaneiformis and investigated its fermentation by rabbitfish intestinal microbes. The study found that the polysaccharide was mainly composed of galactose and anhydrogalactose, and it enhanced the production of short-chain fatty acids and altered the gut microbiota. The findings suggest that the polysaccharide has prebiotic potential and could be used as a functional feed additive in aquaculture.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Microbiology
Yaotong Hao, Yaxian Zhao, Yitong Zhang, Yufeng Liu, Guixing Wang, Zhongwei He, Wei Cao, Tian Han, Xun Zhang, Ziying Zhang, Yufen Wang, Chunguang Gong, Jilun Hou
Summary: This study investigated the intestinal microbial response to different doses of Vibrio alginolyticus infection in half-smooth tongue sole. The results showed that high-dose infection significantly altered the intestinal microbiota, decreased microbial diversity, and increased the number of potential pathogens such as Vibrio and Shewanella.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Environmental Sciences
Ming Zhang, Huifen Liang, Yifan Lei, Yiwen Zhang, Zhigang Tan, Wenzhen Chen, Shengkang Li, Xianfeng Peng, Ngoc Tuan Tran
Summary: This study evaluated the effects of Aspergillus niger on the growth, antioxidative activity, immune response, and gut microbiota of Pacific white shrimps under farming conditions. The results showed that the addition of 1.5 g/kg A. niger significantly promoted the weight gain, specific growth rate, and length gain of shrimps. A. niger supplementation increased the diversity and changed the composition of gut microbiota in shrimps.
FRONTIERS IN MARINE SCIENCE
(2023)
Article
Fisheries
Ming Zhang, Ngoc Tuan Tran, Yongsheng Zhang, Qiuhua Yang, Yong Tang, Yueling Zhang, Shengkang Li
Summary: This study investigates the role of SpNox in regulating the microbiota in the hemolymph and midgut of mud crab. The results show that SpNox generates ROS to modulate the composition of microbiota in these tissues.
Article
Fisheries
Ngoc Tuan Tran, Lianjie Chen, Yanlian Zhou, Ming Zhang, Yilei Wang, Shengkang Li
Summary: In this study, SpTNF was cloned and characterized from mud crab (Scylla paramamosain) for the first time. It was found that SpTNF inhibits WSSV infection through activating apoptosis, NF-κB pathway, and AMP synthesis. The expression and regulation of SpTNF were found to be mediated by SpLITAF, which is induced by WSSV infection.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Fisheries
Ngoc Tuan Tran, Huifen Liang, Jinkun Li, Taoqiu Deng, Md Akibul Hasan Bakky, Ming Zhang, Shengkang Li
Summary: Innate immunity is crucial for protecting crustaceans against pathogens, especially the serious white spot syndrome virus (WSSV). Understanding how hosts respond to WSSV infection is essential for prevention and control. This review summarizes the involvement of signaling pathways and cellular activities in the immune response of crustaceans during WSSV infection, providing important insights into host-pathogen interaction and potential strategies for enhancing immune defense.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Fisheries
Md. Akibul Hasan Bakky, Ngoc Tuan Tran, Yongsheng Zhang, Hang Hu, Haitian Lin, Ming Zhang, Huifen Liang, Yueling Zhang, Shengkang Li
Summary: The dietary supplementation of red seaweed-derived polysaccharides (GLP) has positive effects on the growth, antioxidant activity, and immunity of rabbitfish. It can be used as an immunostimulant and growth promoter in rabbitfish aquaculture.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Food Science & Technology
Ming Zhang, Ngoc Tuan Tran, Peina Ji, Yongsheng Zhang, Daimeng Zhang, Huaiping Zheng, Shengkang Li
Summary: Yellow oil mud crab (YOC) is a new variant of mud crab with high nutrition value. This study aimed to investigate the nutrient compositions, gene differences, and fatty acid synthesis ability of YOC compared to normal mud crabs. The results showed that YOC has higher nutritional value and better fatty acid synthesis ability.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Agriculture, Dairy & Animal Science
Tongtong Kong, Xinyue Fan, Ngoc Tuan Tran
Summary: The composition and function of the hemolymph microbiota in Chinese mitten crab infected with Staphylococcus aureus or Aeromonas hydrophila were studied. Specific phyla and genera were affected, and different functional pathways were enriched.
Article
Microbiology
Huifen Liang, Ngoc Tuan Tran, Tiaoqiu Deng, Jinkun Li, Yifan Lei, Mohammad Akibul Hasan Bakky, Ming Zhang, Rui Li, Wenxuan Chen, Yueling Zhang, Xiuli Chen, Shengkang Li
Summary: This study isolated the butyrate-producing bacterium Clostridium butyricum G13 from the gut of mud crab for the first time. The bacterium showed potential as a probiotic in mud crab aquaculture, improving growth and health benefits, increasing butyric acid production, and maintaining normal gut morphology after Vibrio parahaemolyticus infection.
MICROBIOLOGY SPECTRUM
(2023)
Article
Fisheries
Ngoc Tuan Tran, Huifen Liang, Jinkun Li, Taoqiu Deng, Ming Zhang, Shengkang Li
Summary: Aquaculture plays a crucial role in global food security and nutrition, but disease outbreaks pose significant economic losses. This review explores the potential use of feed additives, such as butyrate and Clostridium butyricum, in improving aquaculture productivity and reducing disease impact in aquatic animals. The study highlights the health benefits of the dietary supplementation of butyrate and C. butyricum, including improved growth, feed utilization, intestinal health, immune response, antioxidant activity, stress tolerance, and infection resistance. The findings suggest that C. butyricum may offer greater benefits compared to butyrate alone.
FISH AND SHELLFISH IMMUNOLOGY REPORTS
(2023)